Compile Data Set for Download or QSAR

Found 284 hits with Last Name = 'yoo' and Initial = 'js'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368342 (US10227338, Example 129) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(Cl)s1 Show InChI InChI=1S/C19H20Cl2FN5O2S2/c1-23-7-8-27(2)16-6-4-3-5-14(16)25-15-10-13(22)17(9-12(15)20)31(28,29)26-19-24-11-18(21)30-19/h3-6,9-11,23,25H,7-8H2,1-2H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368343 (US10227338, Example 130) Show SMILES CNCCN(C)c1cc(OC)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(Cl)s1 Show InChI InChI=1S/C20H22Cl2FN5O3S2/c1-24-6-7-28(2)17-8-12(31-3)4-5-15(17)26-16-10-14(23)18(9-13(16)21)33(29,30)27-20-25-11-19(22)32-20/h4-5,8-11,24,26H,6-7H2,1-3H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368340 (US10227338, Example 127) Show SMILES CNCCN(C)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(Cl)s1 Show InChI InChI=1S/C19H19Cl2F2N5O2S2/c1-24-5-6-28(2)16-7-11(22)3-4-14(16)26-15-9-13(23)17(8-12(15)20)32(29,30)27-19-25-10-18(21)31-19/h3-4,7-10,24,26H,5-6H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368341 (US10227338, Example 128) Show SMILES CNCCN(C)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(F)s1 Show InChI InChI=1S/C19H19ClF3N5O2S2/c1-24-5-6-28(2)16-7-11(21)3-4-14(16)26-15-9-13(22)17(8-12(15)20)32(29,30)27-19-25-10-18(23)31-19/h3-4,7-10,24,26H,5-6H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368324 (US10227338, Example 111) Show SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)C(F)(F)F Show InChI InChI=1S/C20H20ClF4N5O2S2/c1-26-5-7-30(2)17-9-12(20(23,24)25)3-4-15(17)28-16-11-14(22)18(10-13(16)21)34(31,32)29-19-27-6-8-33-19/h3-4,6,8-11,26,28H,5,7H2,1-2H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368272 (US10227338, Example 55) Show SMILES CNC1CCN(C1)c1cc(OC)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C21H23ClFN5O3S2/c1-24-13-5-6-28(10-13)19-7-14(31-2)3-4-17(19)26-18-9-16(23)20(8-15(18)22)33(29,30)27-21-11-32-12-25-21/h3-4,7-9,11-13,24,26-27H,5-6,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368258 (US10227338, Example 40 | US10227338, Example 50) Show SMILES CNC1CCN(C1)c1ccccc1Nc1ccc(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C20H22ClN5O2S2/c1-22-14-8-9-26(11-14)19-5-3-2-4-18(19)24-17-7-6-15(10-16(17)21)30(27,28)25-20-12-29-13-23-20/h2-7,10,12-14,22,24-25H,8-9,11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368220 (US10227338, Example 1 | US10227338, Example 32) Show SMILES CNC1CCN(C1)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C20H20ClF2N5O2S2/c1-24-13-4-5-28(9-13)18-6-12(22)2-3-16(18)26-17-8-15(23)19(7-14(17)21)32(29,30)27-20-10-31-11-25-20/h2-3,6-8,10-11,13,24,26-27H,4-5,9H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368318 (US10227338, Example 105) Show SMILES CNCCN(C)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C19H20ClF2N5O2S2/c1-23-5-7-27(2)17-9-12(21)3-4-15(17)25-16-11-14(22)18(10-13(16)20)31(28,29)26-19-24-6-8-30-19/h3-4,6,8-11,23,25H,5,7H2,1-2H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368339 (US10227338, Example 126) Show SMILES CNCCN(C)c1cc(Cl)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C19H20Cl2FN5O2S2/c1-23-5-7-27(2)17-9-12(20)3-4-15(17)25-16-11-14(22)18(10-13(16)21)31(28,29)26-19-24-6-8-30-19/h3-4,6,8-11,23,25H,5,7H2,1-2H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368347 (US10227338, Example 134) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cc(C)on1 Show InChI InChI=1S/C20H23ClFN5O3S/c1-13-10-20(25-30-13)26-31(28,29)19-11-14(21)17(12-15(19)22)24-16-6-4-5-7-18(16)27(3)9-8-23-2/h4-7,10-12,23-24H,8-9H2,1-3H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368332 (US10227338, Example 119) Show SMILES CNCCN(C)c1cc(OC)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C20H23ClFN5O3S2/c1-23-6-8-27(2)18-10-13(30-3)4-5-16(18)25-17-12-15(22)19(11-14(17)21)32(28,29)26-20-24-7-9-31-20/h4-5,7,9-12,23,25H,6,8H2,1-3H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368327 (US10227338, Example 114 | US10227338, Example 116) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C19H21ClFN5O2S2/c1-22-7-9-26(2)17-6-4-3-5-15(17)24-16-12-14(21)18(11-13(16)20)30(27,28)25-19-23-8-10-29-19/h3-6,8,10-12,22,24H,7,9H2,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368321 (US10227338, Example 108) Show SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1)C#N Show InChI InChI=1S/C20H20ClFN6O2S2/c1-24-5-7-28(2)18-9-13(12-23)3-4-16(18)26-17-11-15(22)19(10-14(17)21)32(29,30)27-20-25-6-8-31-20/h3-4,6,8-11,24,26H,5,7H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368239 (US10227338, Example 20) Show SMILES CNC1CCN(C1)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F Show InChI InChI=1S/C21H20ClF4N5O2S2/c1-27-13-4-5-31(9-13)18-6-12(21(24,25)26)2-3-16(18)29-17-8-15(23)19(7-14(17)22)35(32,33)30-20-10-34-11-28-20/h2-3,6-8,10-11,13,27,29-30H,4-5,9H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368298 (US10227338, Example 81) Show SMILES CN[C@H]1CCN(C1)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F |r| Show InChI InChI=1S/C21H20ClF4N5O2S2/c1-27-13-4-5-31(9-13)18-6-12(21(24,25)26)2-3-16(18)29-17-8-15(23)19(7-14(17)22)35(32,33)30-20-10-34-11-28-20/h2-3,6-8,10-11,13,27,29-30H,4-5,9H2,1H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368221 (US10227338, Example 2) Show SMILES CNC1CCN(C1)c1cc(Cl)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C20H20Cl2FN5O2S2/c1-24-13-4-5-28(9-13)18-6-12(21)2-3-16(18)26-17-8-15(23)19(7-14(17)22)32(29,30)27-20-10-31-11-25-20/h2-3,6-8,10-11,13,24,26-27H,4-5,9H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368344 (US10227338, Example 131) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(F)s1 Show InChI InChI=1S/C19H20ClF2N5O2S2/c1-23-7-8-27(2)16-6-4-3-5-14(16)25-15-10-13(21)17(9-12(15)20)31(28,29)26-19-24-11-18(22)30-19/h3-6,9-11,23,25H,7-8H2,1-2H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368256 (US10227338, Example 38) Show SMILES CNC1CCN(C1)c1cc(ccc1Nc1ccc(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F Show InChI InChI=1S/C21H21ClF3N5O2S2/c1-26-14-6-7-30(10-14)19-8-13(21(23,24)25)2-4-18(19)28-17-5-3-15(9-16(17)22)34(31,32)29-20-11-33-12-27-20/h2-5,8-9,11-12,14,26,28-29H,6-7,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368297 (US10227338, Example 80) Show SMILES CN[C@H]1CCN(C1)c1cc(ccc1Nc1ccc(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F |r| Show InChI InChI=1S/C21H21ClF3N5O2S2/c1-26-14-6-7-30(10-14)19-8-13(21(23,24)25)2-4-18(19)28-17-5-3-15(9-16(17)22)34(31,32)29-20-11-33-12-27-20/h2-5,8-9,11-12,14,26,28-29H,6-7,10H2,1H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368284 (US10227338, Example 67) Show SMILES CN1CCN(CC1)c1cc(OC(F)(F)F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C21H20ClF4N5O3S2/c1-30-4-6-31(7-5-30)18-8-13(34-21(24,25)26)2-3-16(18)28-17-10-15(23)19(9-14(17)22)36(32,33)29-20-11-35-12-27-20/h2-3,8-12,28-29H,4-7H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368308 (US10227338, Example 95) Show SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1)C(F)(F)F Show InChI InChI=1S/C20H20ClF4N5O2S2/c1-26-5-6-30(2)17-7-12(20(23,24)25)3-4-15(17)28-16-9-14(22)18(8-13(16)21)34(31,32)29-19-10-33-11-27-19/h3-4,7-11,26,28-29H,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368294 (US10227338, Example 77) Show SMILES CNC1CCN(C1)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1)C#N Show InChI InChI=1S/C21H20ClFN6O2S2/c1-25-14-4-5-29(10-14)19-6-13(9-24)2-3-17(19)27-18-8-16(23)20(7-15(18)22)33(30,31)28-21-11-32-12-26-21/h2-3,6-8,11-12,14,25,27-28H,4-5,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368220 (US10227338, Example 1 | US10227338, Example 32) Show SMILES CNC1CCN(C1)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C20H20ClF2N5O2S2/c1-24-13-4-5-28(9-13)18-6-12(22)2-3-16(18)26-17-8-15(23)19(7-14(17)21)32(29,30)27-20-10-31-11-25-20/h2-3,6-8,10-11,13,24,26-27H,4-5,9H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368305 (US10227338, Example 92) Show SMILES CN(CCN(C)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)N(C(=O)OC(C)(C)C)c1cscn1)C(=O)OC(C)(C)C Show InChI InChI=1S/C29H36ClF2N5O6S2/c1-28(2,3)42-26(38)36(8)12-11-35(7)23-13-18(31)9-10-21(23)34-22-15-20(32)24(14-19(22)30)45(40,41)37(25-16-44-17-33-25)27(39)43-29(4,5)6/h9-10,13-17,34H,11-12H2,1-8H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368316 (US10227338, Example 103) Show SMILES CN(CCN(C)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)N(C(=O)OC(C)(C)C)c1ccc(F)cn1)C(=O)OC(C)(C)C Show InChI InChI=1S/C31H37ClF3N5O6S/c1-30(2,3)45-28(41)39(8)14-13-38(7)25-15-19(33)9-11-23(25)37-24-17-22(35)26(16-21(24)32)47(43,44)40(29(42)46-31(4,5)6)27-12-10-20(34)18-36-27/h9-12,15-18,37H,13-14H2,1-8H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368311 (US10227338, Example 121 | US10227338, Example 98) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C19H21ClFN5O2S2/c1-22-7-8-26(2)17-6-4-3-5-15(17)24-16-10-14(21)18(9-13(16)20)30(27,28)25-19-11-29-12-23-19/h3-6,9-12,22,24-25H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368249 (US10227338, Example 31) Show SMILES CN[C@@H]1CCN(C1)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 |r| Show InChI InChI=1S/C20H20ClF2N5O2S2/c1-24-13-4-5-28(9-13)18-6-12(22)2-3-16(18)26-17-8-15(23)19(7-14(17)21)32(29,30)27-20-10-31-11-25-20/h2-3,6-8,10-11,13,24,26-27H,4-5,9H2,1H3/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368223 (US10227338, Example 4) Show SMILES CN[C@@H]1CCCN(C1)c1cc(Cl)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 |r| Show InChI InChI=1S/C21H22Cl2FN5O2S2/c1-25-14-3-2-6-29(10-14)19-7-13(22)4-5-17(19)27-18-9-16(24)20(8-15(18)23)33(30,31)28-21-11-32-12-26-21/h4-5,7-9,11-12,14,25,27-28H,2-3,6,10H2,1H3/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368289 (US10227338, Example 72) Show SMILES CN(C)[C@H]1CCN(C1)c1cc(OC(F)F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 |r| Show InChI InChI=1S/C22H23ClF3N5O3S2/c1-30(2)13-5-6-31(10-13)19-7-14(34-22(25)26)3-4-17(19)28-18-9-16(24)20(8-15(18)23)36(32,33)29-21-11-35-12-27-21/h3-4,7-9,11-13,22,28-29H,5-6,10H2,1-2H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368243 (US10227338, Example 24) Show SMILES CN[C@@H]1CCCN(C1)c1cc(F)ccc1Nc1ccc(cc1Cl)S(=O)(=O)Nc1cscn1 |r| Show InChI InChI=1S/C21H23ClFN5O2S2/c1-24-15-3-2-8-28(11-15)20-9-14(23)4-6-19(20)26-18-7-5-16(10-17(18)22)32(29,30)27-21-12-31-13-25-21/h4-7,9-10,12-13,15,24,26-27H,2-3,8,11H2,1H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368322 (US10227338, Example 109) Show SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccc(F)cn1)C(F)(F)F Show InChI InChI=1S/C22H21ClF5N5O2S/c1-29-7-8-33(2)19-9-13(22(26,27)28)3-5-17(19)31-18-11-16(25)20(10-15(18)23)36(34,35)32-21-6-4-14(24)12-30-21/h3-6,9-12,29,31H,7-8H2,1-2H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368287 (US10227338, Example 70) Show SMILES CN[C@H]1CCN(C1)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 |r| Show InChI InChI=1S/C20H20ClF2N5O2S2/c1-24-13-4-5-28(9-13)18-6-12(22)2-3-16(18)26-17-8-15(23)19(7-14(17)21)32(29,30)27-20-10-31-11-25-20/h2-3,6-8,10-11,13,24,26-27H,4-5,9H2,1H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368336 (US10227338, Example 123) Show SMILES CNCCN(C)c1cc(Cl)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C19H20Cl2FN5O2S2/c1-23-5-6-27(2)17-7-12(20)3-4-15(17)25-16-9-14(22)18(8-13(16)21)31(28,29)26-19-10-30-11-24-19/h3-4,7-11,23,25-26H,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368327 (US10227338, Example 114 | US10227338, Example 116) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nccs1 Show InChI InChI=1S/C19H21ClFN5O2S2/c1-22-7-9-26(2)17-6-4-3-5-15(17)24-16-12-14(21)18(11-13(16)20)30(27,28)25-19-23-8-10-29-19/h3-6,8,10-12,22,24H,7,9H2,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368354 (US10227338, Example 141) Show SMILES CNCCN(C)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(C)s1 Show InChI InChI=1S/C20H22ClF2N5O2S2/c1-12-11-25-20(31-12)27-32(29,30)19-9-14(21)17(10-15(19)23)26-16-5-4-13(22)8-18(16)28(3)7-6-24-2/h4-5,8-11,24,26H,6-7H2,1-3H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368254 (US10227338, Example 36) Show SMILES CNC1CCN(C1)c1ccccc1Nc1ccc(cc1)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C20H23N5O2S2/c1-21-16-10-11-25(12-16)19-5-3-2-4-18(19)23-15-6-8-17(9-7-15)29(26,27)24-20-13-28-14-22-20/h2-9,13-14,16,21,23-24H,10-12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368257 (US10227338, Example 39 | US10227338, Example 49) Show SMILES CNC1CCN(C1)c1ccccc1Nc1ccc(c(F)c1)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C20H22FN5O2S2/c1-22-15-8-9-26(11-15)18-5-3-2-4-17(18)24-14-6-7-19(16(21)10-14)30(27,28)25-20-12-29-13-23-20/h2-7,10,12-13,15,22,24-25H,8-9,11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368236 (US10227338, Example 17) Show SMILES CNC1CCN(C1)c1cc(OC(F)(F)F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C21H20ClF4N5O3S2/c1-27-12-4-5-31(9-12)18-6-13(34-21(24,25)26)2-3-16(18)29-17-8-15(23)19(7-14(17)22)36(32,33)30-20-10-35-11-28-20/h2-3,6-8,10-12,27,29-30H,4-5,9H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368255 (US10227338, Example 37) Show SMILES CNC1CCN(C1)c1cc(ccc1Nc1ccc(c(F)c1)S(=O)(=O)Nc1cscn1)C(F)(F)F Show InChI InChI=1S/C21H21F4N5O2S2/c1-26-15-6-7-30(10-15)18-8-13(21(23,24)25)2-4-17(18)28-14-3-5-19(16(22)9-14)34(31,32)29-20-11-33-12-27-20/h2-5,8-9,11-12,15,26,28-29H,6-7,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368311 (US10227338, Example 121 | US10227338, Example 98) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C19H21ClFN5O2S2/c1-22-7-8-26(2)17-6-4-3-5-15(17)24-16-10-14(21)18(9-13(16)20)30(27,28)25-19-11-29-12-23-19/h3-6,9-12,22,24-25H,7-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368310 (US10227338, Example 97) Show SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(F)cn1)C(F)(F)F Show InChI InChI=1S/C21H20ClF5N6O2S/c1-28-5-6-33(2)18-7-12(21(25,26)27)3-4-16(18)31-17-9-15(24)19(8-14(17)22)36(34,35)32-20-29-10-13(23)11-30-20/h3-4,7-11,28,31H,5-6H2,1-2H3,(H,29,30,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368352 (US10227338, Example 139) Show SMILES CN(C)CCN(C)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(Cl)s1 Show InChI InChI=1S/C20H21Cl2F2N5O2S2/c1-28(2)6-7-29(3)17-8-12(23)4-5-15(17)26-16-10-14(24)18(9-13(16)21)33(30,31)27-20-25-11-19(22)32-20/h4-5,8-11,26H,6-7H2,1-3H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368240 (US10227338, Example 21 | US10227338, Example 52) Show SMILES CNC1CCN(C1)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C20H21ClFN5O2S2/c1-23-13-6-7-27(10-13)18-5-3-2-4-16(18)25-17-9-15(22)19(8-14(17)21)31(28,29)26-20-11-30-12-24-20/h2-5,8-9,11-13,23,25-26H,6-7,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368244 (US10227338, Example 26) Show SMILES CN[C@@H]1CCCN(C1)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 |r| Show InChI InChI=1S/C21H22ClF2N5O2S2/c1-25-14-3-2-6-29(10-14)19-7-13(23)4-5-17(19)27-18-9-16(24)20(8-15(18)22)33(30,31)28-21-11-32-12-26-21/h4-5,7-9,11-12,14,25,27-28H,2-3,6,10H2,1H3/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368240 (US10227338, Example 21 | US10227338, Example 52) Show SMILES CNC1CCN(C1)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 Show InChI InChI=1S/C20H21ClFN5O2S2/c1-23-13-6-7-27(10-13)18-5-3-2-4-16(18)25-17-9-15(22)19(8-14(17)21)31(28,29)26-20-11-30-12-24-20/h2-5,8-9,11-13,23,25-26H,6-7,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368325 (US10227338, Example 112 | US10227338, Example 115) Show SMILES CNCCN(C)c1ccccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccc(F)cn1 Show InChI InChI=1S/C21H22ClF2N5O2S/c1-25-9-10-29(2)19-6-4-3-5-17(19)27-18-12-16(24)20(11-15(18)22)32(30,31)28-21-8-7-14(23)13-26-21/h3-8,11-13,25,27H,9-10H2,1-2H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368323 (US10227338, Example 110) Show SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccccn1)C(F)(F)F Show InChI InChI=1S/C22H22ClF4N5O2S/c1-28-9-10-32(2)19-11-14(22(25,26)27)6-7-17(19)30-18-13-16(24)20(12-15(18)23)35(33,34)31-21-5-3-4-8-29-21/h3-8,11-13,28,30H,9-10H2,1-2H3,(H,29,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368277 (US10227338, Example 60) Show SMILES CN[C@@H]1CCCN(C1)c1cc(OC)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1 |r| Show InChI InChI=1S/C22H25ClFN5O3S2/c1-25-14-4-3-7-29(11-14)20-8-15(32-2)5-6-18(20)27-19-10-17(24)21(9-16(19)23)34(30,31)28-22-12-33-13-26-22/h5-6,8-10,12-14,25,27-28H,3-4,7,11H2,1-2H3/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM368309 (US10227338, Example 96) Show SMILES CN(CCN(C)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)N(C(=O)OC(C)(C)C)c1ncc(F)cn1)C(=O)OC(C)(C)C Show InChI InChI=1S/C30H36ClF3N6O6S/c1-29(2,3)45-27(41)39(8)12-11-38(7)24-13-18(32)9-10-22(24)37-23-15-21(34)25(14-20(23)31)47(43,44)40(28(42)46-30(4,5)6)26-35-16-19(33)17-36-26/h9-10,13-17,37H,11-12H2,1-8H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca					Assay Description In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...				J Med Chem 51: 1755-1763 (2008) BindingDB Entry DOI: 10.7270/Q2F47RFM
					More data for this Ligand-Target Pair

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