Found 391 hits Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid (GABA) B receptor 1' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24198
(3-aminopropylphosphinic derivative, (R)-8 | [(2R)-...)Show InChI InChI=1S/C4H11FNO2P/c1-9(7,8)3-4(5)2-6/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 4.30 | -47.3 | n/a | n/a | 14 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24195
(3-aminopropylphosphinic derivative, (R)-7 | AZD335...)Show InChI InChI=1S/C3H9FNO2P/c4-3(1-5)2-8(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 5.10 | -46.9 | n/a | n/a | 8.64 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24193
((3-amino-2-fluoropropyl)phosphinic acid | 3-aminop...)Show InChI InChI=1S/C3H9FNO2P/c4-3(1-5)2-8(6)7/h3,8H,1-2,5H2,(H,6,7) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | -45.2 | n/a | n/a | 15 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24196
((3-amino-2-fluoropropyl)(methyl)phosphinic acid | ...)Show InChI InChI=1S/C4H11FNO2P/c1-9(7,8)3-4(5)2-6/h4H,2-3,6H2,1H3,(H,7,8) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | -44.4 | n/a | n/a | 23 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24184
((3-aminopropyl)phosphinic acid | 3-aminopropylphos...)Show InChI InChI=1S/C3H10NO2P/c4-2-1-3-7(5)6/h7H,1-4H2,(H,5,6) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 15 | -44.2 | n/a | n/a | 19 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24185
((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)Show InChI InChI=1S/C4H12NO2P/c1-8(6,7)4-2-3-5/h2-5H2,1H3,(H,6,7) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 33 | -42.3 | n/a | n/a | 41 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24191
((3-amino-2-oxopropyl)phosphinic acid | (3-amino-2-...)Show InChI InChI=1S/C3H8NO3P/c4-1-3(5)2-8(6)7/h8H,1-2,4H2,(H,6,7) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 48 | -41.4 | n/a | n/a | 81 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24186
((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)Show InChI InChI=1S/C3H8NO3P/c4-1-3(5)2-8(6)7/h6-7H,1-2,4H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 50 | -41.3 | n/a | n/a | 130 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24194
(3-aminopropylphosphinic derivative, (S)-7 | [(2S)-...)Show InChI InChI=1S/C3H9FNO2P/c4-3(1-5)2-8(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 70 | -40.4 | n/a | n/a | 250 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24186
((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)Show InChI InChI=1S/C3H8NO3P/c4-1-3(5)2-8(6)7/h6-7H,1-2,4H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 94 | -39.7 | n/a | n/a | 220 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24189
(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)Show InChI InChI=1S/C4H12NO3P/c1-9(7,8)3-4(6)2-5/h7-9H,2-3,5H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 180 | -38.1 | n/a | n/a | 150 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24192
((3-amino-2-oxopropyl)(methyl)phosphinic acid | (3-...)Show InChI InChI=1S/C4H10NO3P/c1-9(7,8)3-4(6)2-5/h2-3,5H2,1H3,(H,7,8) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 200 | -37.9 | n/a | n/a | 270 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24182
(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)Show InChI InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 220 | -37.6 | n/a | n/a | 750 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24197
(3-aminopropylphosphinic derivative, (S)-8 | [(2S)-...)Show InChI InChI=1S/C4H11FNO2P/c1-9(7,8)3-4(5)2-6/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 480 | -35.7 | n/a | n/a | 1.70E+3 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24189
(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)Show InChI InChI=1S/C4H12NO3P/c1-9(7,8)3-4(6)2-5/h7-9H,2-3,5H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 840 | -34.3 | n/a | n/a | 600 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1/type B receptor subunit 2 [41-940]
(Rattus norvegicus (rat)) | BDBM24186
((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)Show InChI InChI=1S/C3H8NO3P/c4-1-3(5)2-8(6)7/h6-7H,1-2,4H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.10E+3 | -32.1 | n/a | n/a | 1.10E+3 | n/a | n/a | 7.4 | 22 |
AstraZeneca
| Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... |
J Med Chem 51: 4315-20 (2008)
Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM104978
(US8575375, C-8)Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)C(CC[C@@H]2[N+]([O-])=O)C2CC[C@H]3C[C@](C)(O)CCC3C12 |r| Show InChI InChI=1S/C27H40N2O3/c1-26(30)14-13-20-18(15-26)7-10-21-23-11-12-24(29(31)32)27(23,2)16-22(25(20)21)17-5-8-19(9-6-17)28(3)4/h5-6,8-9,18,20-25,30H,7,10-16H2,1-4H3/t18-,20?,21?,22+,23?,24-,25?,26+,27-/m0/s1 | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 9.79 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute; The United States of America, as represented by the Secretary, Department of Health and Human Services
US Patent
| Assay Description [35S]TBPS binding assay. |
US Patent US8575375 (2013)
BindingDB Entry DOI: 10.7270/Q2ST7NGT |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585854
(US11530237, Compound 10 | US11542297, Compound 10)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc(cn1)C#N |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585855
(US11530237, Compound 11 | US11542297, Compound 11)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccccc2n1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585856
(US11530237, Compound 12 | US11542297, Compound 12)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccccc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585858
(US11530237, Compound 14 | US11542297, Compound 14)Show SMILES COc1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585859
(US11530237, Compound 15 | US11542297, Compound 15)Show SMILES COc1ccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc2c1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585860
(US11530237, Compound 16 | US11542297, Compound 16)Show SMILES COc1ccc2nnn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585862
(US11530237, Compound 18 | US11542297, Compound 18)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2c(F)cccc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585863
(US11530237, Compound 19 | US11542297, Compound 19)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ccc(n1)C(F)(F)F |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585864
(US11530237, Compound 21 | US11542297, Compound 21)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(F)cc2n1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585865
(US11530237, Compound 22 | US11542297, Compound 22)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccc(F)cc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585866
(US11530237, Compound 23 | US11542297, Compound 23)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)ccc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585867
(US11530237, Compound 24 | US11542297, Compound 24)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ccc(n1)C#N |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585868
(US11530237, Compound 26 | US11542297, Compound 26)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc2ccccc2n1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585870
(US11530237, Compound 28 | US11542297, Compound 28)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2cc(F)cc(F)c2n1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585871
(US11530237, Compound 29 | US11542297, Compound 29)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)cc(F)c12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585874
(US11530237, Compound 32)Show SMILES Cc1nnn(CC(=O)[C@@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)n1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585877
(US11530237, Compound 35 | US11542297, Compound 35)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(Cl)cc2n1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585878
(US11530237, Compound 36 | US11542297, Compound 36)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccc(Cl)cc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585882
(US11530237, Compound 40 | US11542297, Compound 40)Show SMILES CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5ccc(n5)C(=O)OCC)[C@@]4(C)CC[C@H]23)C[C@@H]1O |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585886
(US11530237, Compound 45 | US11542297, Compound 45)Show SMILES COc1cccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585891
(US11530237, Compound 50)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ncc2cc(Cl)cnc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585894
(US11530237, Compound 53 | US11542297, Compound 53)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(Cl)c(F)c2n1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585895
(US11530237, Compound 54 | US11542297, Compound 54)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ncnn1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585915
(US11530237, Compound 74 | US11542297, Compound 74)Show SMILES CSc1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585919
(US11530237, Compound 78 | US11542297, Compound 78)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2c(F)c(F)ccc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585922
(US11530237, Compound 169 | US11530237, Compound 86...)Show SMILES CN(C)C(=O)c1cnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)c1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585932
(US11530237, Compound 103)Show SMILES CS(=O)c1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585933
(US11530237, Compound 104)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(cc2n1)S(C)(=O)=O |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585946
(US11530237, Compound 117 | US11542297, Compound 11...)Show SMILES COc1cccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585951
(US11530237, Compound 124 | US11542297, Compound 12...)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)c(F)cc12 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585939
(US11530237, Compound 110 | US11530237, Compound 12...)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2cccc(F)c2n1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585959
(US11530237, Compound 133 | US11542297, Compound 13...)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc(Cl)cn1 |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585971
(US11530237, Compound 146)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc(cn1)B(O)O |r| | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this Ligand-Target Pair | |