Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218675 (US9290501, PT-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0350 | -59.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM50247150 (5'-phenylthio-ImmH | CHEMBL474328 | US9290501, (B)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 0.0350 | -59.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218673 (US9290501, PrT-DADMe-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0720 | -57.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM50247149 (5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | US Patent | 0.0760 | -57.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218674 (US9290501, MT-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0760 | -57.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM50246594 ((+/-)-7-((1-hydroxy-3-(methylthio)propan-2-ylamino...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 0.0960 | -57.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM50246594 ((+/-)-7-((1-hydroxy-3-(methylthio)propan-2-ylamino...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 0.0960 | -57.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM50247151 (7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 0.340 | -54.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218676 (US9290501, MT-DADMe-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.340 | -54.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218673 (US9290501, PrT-DADMe-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.380 | -53.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218675 (US9290501, PT-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.660 | -52.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM50246594 ((+/-)-7-((1-hydroxy-3-(methylthio)propan-2-ylamino...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 0.720 | -52.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218676 (US9290501, MT-DADMe-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.800 | -51.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218674 (US9290501, MT-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.840 | -51.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM218677 (US9290501, 4'-HO-MT-DADMe-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.21 | -50.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-methyl-5'-thioinosine phosphorylase (Pseudomonas aeruginosa) | BDBM136302 (US8853224, 12 | US9290501, MT-TrisMe-ImmH) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 19 | -44.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Albert Einstein College of Medicine, Inc.; Victoria Link Limited US Patent | Assay Description Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ... | US Patent US9290501 (2016) BindingDB Entry DOI: 10.7270/Q2639NKD | |||||||||||
More data for this Ligand-Target Pair |