Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SGLT1 protein (Mus musculus (Mouse)) | BDBM109275 (US8609622, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109277 (US8609622, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109280 (US8609622, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109275 (US8609622, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109274 (US8609622, 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109276 (US8609622, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109278 (US8609622, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109277 (US8609622, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM50340014 (4-((5-(4-chlorobenzylthio)-4-methyl-4H-1,2,4-triaz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of mouse SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillat... | Bioorg Med Chem Lett 21: 2472-5 (2011) Article DOI: 10.1016/j.bmcl.2011.02.056 BindingDB Entry DOI: 10.7270/Q25Q4WD2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109277 (US8609622, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SGLT1 protein (Mus musculus (Mouse)) | BDBM109279 (US8609622, 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair |