Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptase gamma (Homo sapiens (Human)) | BDBM23891 (3-amidinophenylalanine deriv., 35 | CHEMBL107955 |...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universität Jena Curated by ChEMBL | Assay Description Compound was tested for inhibition of tryptase | Bioorg Med Chem Lett 9: 3147-52 (1999) BindingDB Entry DOI: 10.7270/Q2RB73S3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50302107 (CHEMBL567893 | Grassystatin A) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Inhibition of human lung tryptase gamma1 after 10 to 15 mins by fluorescence assay | J Med Chem 52: 5732-47 (2009) Article DOI: 10.1021/jm9009394 BindingDB Entry DOI: 10.7270/Q2BG2PXP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50067529 (2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetyl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50067528 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50067522 (2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetyl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50067524 (3-(3-Carbamimidoyl-phenyl)-2-[2-(4-cyano-benzenesu...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50067526 (2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetyl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50067523 (2-[2-(4-Carbamimidoyl-benzenesulfonylamino)-acetyl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50067527 (3-(4-Carbamimidoyl-phenyl)-2-[2-(4-thiocarbamoyl-b...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50067530 (3-(4-Carbamimidoyl-phenyl)-2-[2-(4-cyano-benzenesu...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against Tryptase. | J Med Chem 41: 4240-50 (1998) Article DOI: 10.1021/jm980227t BindingDB Entry DOI: 10.7270/Q27D2T86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50093153 (CHEMBL306620 | Derivative of APC-2059) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Dissociation cosntant of compound was evaluated from its IC50 against tryptase at different concentrations | Bioorg Med Chem Lett 10: 2361-6 (2001) BindingDB Entry DOI: 10.7270/Q2HX1BWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50093142 (1,5-di{4-[4-amino(imino)methylaminobenzylcarbamoyl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Dissociation cosntant of compound was evaluated from its IC50 against tryptase at different concentrations | Bioorg Med Chem Lett 10: 2361-6 (2001) BindingDB Entry DOI: 10.7270/Q2HX1BWR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase gamma (Homo sapiens (Human)) | BDBM50093142 (1,5-di{4-[4-amino(imino)methylaminobenzylcarbamoyl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a |
Axys Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Dissociation cosntant of compound was evaluated from its IC50 against tryptase at different concentrations | Bioorg Med Chem Lett 10: 2357-60 (2001) BindingDB Entry DOI: 10.7270/Q2NP23NX | |||||||||||
More data for this Ligand-Target Pair |