Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223720![]() (CHEMBL332257) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223731![]() (CHEMBL118603) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223721![]() (CHEMBL331513) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223726![]() (CHEMBL117331) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223735![]() (CHEMBL119139) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223734![]() (CHEMBL331942) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223733![]() (CHEMBL120306) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223722![]() (CHEMBL334104) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143966![]() (2-Chloro-N-[2-{4-[3-(4-fluoro-phenoxy)-2-hydroxy-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223723![]() (CHEMBL119494) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143963![]() (CHEMBL64869 | N-[2-{4-[3-(4-Bromo-phenoxy)-2-hydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description Inhibitory concentration against [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in vitro in rat cerebral cortex membrane at ... | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223725![]() (CHEMBL118682) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082319![]() ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082324![]() ((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473876![]() (CHEMBL2112614) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223729![]() (CHEMBL418863) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143950![]() (CHEMBL305591 | N-Benzyl-2-{4-[3-(2,6-dimethyl-phen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 149 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143952![]() (CHEMBL59712 | N-{1-[2-Hydroxy-3-(4-methoxy-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 183 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082323![]() (4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143954![]() (CHEMBL433100 | N-(4-Fluoro-phenyl)-N-{1-[2-hydroxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143958![]() (CHEMBL63060 | N-(4-Fluoro-phenyl)-N-{1-[2-hydroxy-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 194 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143962![]() (CHEMBL62878 | N-(2-{4-[3-(4-Chloro-phenoxy)-2-hydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 208 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143964![]() (4-Chloro-N-(4-fluoro-phenyl)-N-{1-[2-hydroxy-3-(4-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 214 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143975![]() (2-(4-Fluoro-phenyl)-2-{4-[2-hydroxy-3-(4-methoxy-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 214 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082319![]() ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143945![]() (4-Chloro-N-{1-[2-hydroxy-3-(4-methoxy-phenoxy)-pro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143970![]() (CHEMBL61336 | N-(2-{4-[2-Hydroxy-3-(4-methoxy-phen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description Inhibitory concentration against [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in vitro in rat cerebral cortex membrane at ... | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143957![]() (CHEMBL60847 | N-Benzyl-2-(4-fluoro-phenyl)-2-{4-[2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 254 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473882![]() (CHEMBL126206) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 255 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143961![]() (CHEMBL62240 | N-{1-[2-Hydroxy-3-(4-methoxy-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 261 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50017702![]() (1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143949![]() (CHEMBL60843 | N-Benzyl-2-{4-[3-(2,6-dimethyl-pheno...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 296 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082320![]() (4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223732![]() (CHEMBL118626) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 322 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473870![]() (CHEMBL2112617) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 322 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143967![]() (CHEMBL60568 | N-Benzyl-2-{4-[3-(2,6-dimethyl-pheno...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 325 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143976![]() (2-{4-[3-(2,6-Dimethyl-phenoxy)-2-hydroxy-propyl]-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 343 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143956![]() (2-{4-[3-(2,6-Dimethyl-phenoxy)-2-hydroxy-propyl]-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 351 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143974![]() (2-{4-[3-(2,6-Dimethyl-phenoxy)-2-hydroxy-propyl]-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143955![]() (2-{4-[2-Hydroxy-3-(4-methoxy-phenoxy)-propyl]-pipe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 359 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082322![]() (1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143965![]() (CHEMBL60666 | N-(2-{4-[3-(4-Chloro-phenoxy)-2-hydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 363 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143947![]() (4-Fluoro-N-{2-[4-(2-hydroxy-3-phenoxy-propyl)-pipe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 363 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473868![]() (CHEMBL339108) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 379 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143951![]() (1-Allyloxy-3-{4-[(4-chloro-phenyl)-phenyl-methyl]-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 401 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143971![]() (CHEMBL59644 | N-Benzyl-2-{4-[2-hydroxy-3-(4-methox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 429 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473883![]() (CHEMBL2111817) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 452 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473869![]() (Lifarizine | RS-87476-000) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 494 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50223728![]() (CHEMBL119103) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 518 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain | Bioorg Med Chem Lett 14: 3521-3 (2004) BindingDB Entry DOI: 10.7270/Q2474D2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50143969![]() (CHEMBL64583 | N-(2-{4-[3-(4-Bromo-phenoxy)-2-hydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 522 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc Curated by ChEMBL | Assay Description In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane | Bioorg Med Chem Lett 14: 2025-30 (2004) Article DOI: 10.1016/j.bmcl.2004.02.078 BindingDB Entry DOI: 10.7270/Q22J6B8R | |||||||||||
More data for this Ligand-Target Pair |
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