Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM172369 (US9090596, 50) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add... | US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM291181 (6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM172372 (US9090596, 53) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add... | US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM291172 (2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM236791 (US9388149, 22 | US9580412, Example 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM291172 (2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM172342 (US9090596, 22) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add... | US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM172328 (US9090596, 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The experiments were carried out on the FLIPR TETRA.RTM. platform from Molecular Devices. After the basal level had been read, the compounds were add... | US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463591 (CHEMBL4248604) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531207 ((R)-3-((3-chloro-2-hydroxyphenyl)amino)-4-((5,5-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531086 ((R)-6-chloro-3-((2-((2,2-dimethyl-1-phenylpropyl)a...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM236795 (US9388149, 2 (Diastereoisomer 1) | US9388149, 2 (D...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM236795 (US9388149, 2 (Diastereoisomer 1) | US9388149, 2 (D...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531125 ((R)-3-((2-((5,5-dimethyl-4,5,6,7-tetrahydrobenzofu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM236789 (US9388149, 20 | US9580412, Example 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531139 (6-chloro-3-((2-((2,2-dimethyl-1-phenylbutyl)amino)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM291177 (US9580412, Example 6 | US9580412, Example 7 | meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM236788 (US9388149, 19 | US9580412, Example 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
GALDERMA RESEARCH & DEVELOPMENT US Patent | Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a... | US Patent US9580412 (2017) BindingDB Entry DOI: 10.7270/Q2222WT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531128 ((R)-6-chloro-3-((2-((5,5-dimethyl-4,5,6,7-tetrahyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463603 (CHEMBL4239904) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463578 (CHEMBL4250007) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531113 (6-chloro-3-((3,4-dioxo-2-((4,5,6,7-tetrahydrobenzo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531147 (6-chloro-3-((2-((6,6-dimethyl-4,5,6,7-tetrahydrobe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531124 (3-((2-((5,5-dimethyl-4,5,6,7-tetrahydrobenzofuran-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463599 (CHEMBL4245355) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463583 (CHEMBL4242040) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531148 (3-((2-((6,6-dimethyl-4,5,6,7-tetrahydrobenzofuran-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531188 (3-((4-chloro-2-hydroxy-3-((4-methylpiperazin-1-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531133 (6-chloro-3-((2-((2,2-dimethyl-1-(5-methylfuran-2-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463604 (CHEMBL4251268) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531121 (6-chloro-3-((2-((2,2-dimethyl-1-(m-tolyl)propyl)am...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531160 (6-chloro-3-((2-((2,2-dimethylcyclohexyl)amino)-3,4...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531144 (3-((5,5-dimethyl-4,5,6,7-tetrahydrobenzofuran-4-yl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531083 (6-chloro-3-((2-((2,2-dimethyl-1,2,3,4-tetrahydrona...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531132 (6-chloro-3-((2-((1-(furan-2-yl)-2,2-dimethylpropyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463579 (CHEMBL4249063) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531181 (6-chloro-3-((2-((cyclopentyl(phenyl)methyl)amino)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531127 (6-chloro-3-((2-((5,5-dimethyl-4,5,6,7-tetrahydrobe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531182 (6-chloro-2-hydroxy-3-((2-((1-(2-methoxyethyl)cyclo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463591 (CHEMBL4248604) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | <30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in human CCL20-dependent cell migration incubated for 4 hrs by Diff-Quik stainin... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531120 (6-chloro-2-hydroxy-3-((2-((1-(3-methoxyphenyl)-2,2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531122 (6-chloro-3-((3,4-dioxo-2-((2,3,3-trimethylbutan-2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531193 (6-chloro-3-((2-((1-ethylcyclopentyl)amino)-3,4-dio...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531145 (3-((4-chloro-2-hydroxy-3-((4-methylpiperazin-1-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463601 (CHEMBL4239428) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in CCL20-induced reduction of forskolin-stimulated cAMP accumulation preincubate... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531208 (6-chloro-2-hydroxy-N,N-dimethyl-3-((2-((1-methylcy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531195 (3-((4-chloro-2-hydroxy-3-((4-methylpiperazin-1-yl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM50463583 (CHEMBL4242040) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited Curated by ChEMBL | Assay Description Inhibition of human CCR6 expressed in CHO cells assessed as decrease in human CCL20-dependent cell migration incubated for 4 hrs by Diff-Quik stainin... | Bioorg Med Chem Lett 28: 3067-3072 (2018) Article DOI: 10.1016/j.bmcl.2018.07.042 BindingDB Entry DOI: 10.7270/Q2DF6TWP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531140 (6-chloro-3-((3,4-dioxo-2-((2,2,4,4-tetramethylpent...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 6 (Homo sapiens (Human)) | BDBM531141 (6-chloro-3-((2-((2,2-dimethylpentan-3-yl)amino)-3,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description HEK-Gqi5 cells stably expressing human CCR6 were cultured in DMEM high glucose, 10% FBS, 1% PSA, 400 ug/ml geneticin and 50 ug/ml hygromycin. Appropr... | Citation and Details BindingDB Entry DOI: 10.7270/Q22F7RMJ | |||||||||||
More data for this Ligand-Target Pair |
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