Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine protease 1 (Rattus norvegicus) | BDBM98601 ((2S)-6-[[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.70 | -11.3 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98587 ((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | US Patent | 6.80 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98599 ((2S)-6-amino-2-[[(2R)-2-(benzylsulfonylamino)-3-hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.80 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98600 ((2S)-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-pr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 7 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98590 ((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 11 | -10.8 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98583 (4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 13 | -10.7 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98593 (US8476306, 6.19 | methyl 4-[[(1R)-2-[[(1S)-2-[(4-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 20 | -10.5 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98588 ((2S)-3-amino-2-[[(2R)-2-(benzylsulfonylamino)-3-hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 21 | -10.4 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98584 (3-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 21 | -10.4 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM50231520 ((R)-N-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-h...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | 22 | -10.4 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98603 (3-amino-N-[4-[[(2S)-2-[[(2R)-2-(benzylsulfonylamin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 25 | -10.3 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98589 ((2S)-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-pr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 30 | -10.2 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98591 (3-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 58 | -9.83 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98592 (4-[[(1R)-2-[[(1S)-2-[(4-carbamimidoylphenyl)methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 100 | -9.51 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98596 ((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 110 | -9.45 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM50110015 (CHEMBL158936 | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | US Patent | 150 | -9.27 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98602 (3-amino-N-[4-[[2-[[(2R)-3-amino-2-(benzylsulfonyla...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 180 | -9.16 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98579 (US8476306, 6.4 | methyl 4-[[(1R)-2-[[2-[(4-carbami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 180 | -9.16 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98595 ((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 210 | -9.07 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98586 ((2R)-2-[[4-(aminomethyl)phenyl]methylsulfonylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 280 | -8.90 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM50110015 (CHEMBL158936 | N-(BENZYLSULFONYL)SERYL-N~1~-{4-[AM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | US Patent | 290 | -8.88 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98604 (2-[4-[[(1R)-2-[[2-[4-[(3-amino-4-methoxy-benzoyl)a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | US Patent | 300 | -8.86 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98585 ((2R)-N-[(1S)-2-[(4-carbamimidoylphenyl)methylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 340 | -8.79 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98594 ((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 350 | -8.77 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98581 (US8476306, 6.6 | methyl 2-[[(1R)-2-[[2-[(4-carbami...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 400 | -8.69 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98598 ((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 410 | -8.68 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98580 (4-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 480 | -8.59 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98597 ((2R)-N-[2-[(4-carbamimidoylphenyl)methylamino]-2-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 600 | -8.45 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98578 (3-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 720 | -8.35 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Rattus norvegicus) | BDBM98582 (2-[[(1R)-2-[[2-[(4-carbamimidoylphenyl)methylamino...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.40E+3 | -7.64 | n/a | n/a | n/a | n/a | n/a | n/a | 24 |
The Medicines Company US Patent | Assay Description Inhibition constant of the compound against Trypsin | US Patent US8476306 (2013) BindingDB Entry DOI: 10.7270/Q2154FPH | |||||||||||
More data for this Ligand-Target Pair |