Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Mus musculus (Mouse)) | BDBM50414514 (PROTOCATECHUAMIDE) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL | Assay Description Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysis | Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM50296245 (3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benz...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL | Assay Description Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysis | Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM29612 (CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL | Assay Description Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysis | Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM50020713 (CHEMBL460860) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Chinese University of Hong Kong Curated by ChEMBL | Assay Description Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 240 uM by Lineweaver-Burk plot | J Nat Prod 77: 1270-4 (2014) Article DOI: 10.1021/np4008798 BindingDB Entry DOI: 10.7270/Q2MK6FFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM50020713 (CHEMBL460860) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.80E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Chinese University of Hong Kong Curated by ChEMBL | Assay Description Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plot | J Nat Prod 77: 1270-4 (2014) Article DOI: 10.1021/np4008798 BindingDB Entry DOI: 10.7270/Q2MK6FFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM23926 ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.90E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Chinese University of Hong Kong Curated by ChEMBL | Assay Description Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plot | J Nat Prod 77: 1270-4 (2014) Article DOI: 10.1021/np4008798 BindingDB Entry DOI: 10.7270/Q2MK6FFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM50020713 (CHEMBL460860) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.10E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Chinese University of Hong Kong Curated by ChEMBL | Assay Description Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 60 uM by Lineweaver-Burk plot | J Nat Prod 77: 1270-4 (2014) Article DOI: 10.1021/np4008798 BindingDB Entry DOI: 10.7270/Q2MK6FFJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Chinese University of Hong Kong Curated by ChEMBL | Assay Description Inhibition of tyrosinase in mouse Melan-a cells assessed as decrease in L-DOPA Vmax at 120 uM by Lineweaver-Burk plot | J Nat Prod 77: 1270-4 (2014) Article DOI: 10.1021/np4008798 BindingDB Entry DOI: 10.7270/Q2MK6FFJ | |||||||||||
More data for this Ligand-Target Pair |