Compile Data Set for Download or QSAR

Found 156 hits Enz. Inhib. hit(s) with all data for entry = 2791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291173 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ncc(cc2n1)-c1c(F)cccc1F |r| Show InChI InChI=1S/C26H24F2N6O/c1-15-9-17(29)14-34(13-15)24-7-8-30-12-23(24)33-26(35)21-6-5-20-22(32-21)10-16(11-31-20)25-18(27)3-2-4-19(25)28/h2-8,10-12,15,17H,9,13-14,29H2,1H3,(H,33,35)/t15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291173 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ncc(cc2n1)-c1c(F)cccc1F |r| Show InChI InChI=1S/C26H24F2N6O/c1-15-9-17(29)14-34(13-15)24-7-8-30-12-23(24)33-26(35)21-6-5-20-22(32-21)10-16(11-31-20)25-18(27)3-2-4-19(25)28/h2-8,10-12,15,17H,9,13-14,29H2,1H3,(H,33,35)/t15-,17+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291175 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES CC(C)c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C23H28N6O/c1-14(2)16-9-20-18(26-10-16)4-5-19(27-20)23(30)28-21-11-25-7-6-22(21)29-12-15(3)8-17(24)13-29/h4-7,9-11,14-15,17H,8,12-13,24H2,1-3H3,(H,28,30)/t15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291175 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES CC(C)c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C23H28N6O/c1-14(2)16-9-20-18(26-10-16)4-5-19(27-20)23(30)28-21-11-25-7-6-22(21)29-12-15(3)8-17(24)13-29/h4-7,9-11,14-15,17H,8,12-13,24H2,1-3H3,(H,28,30)/t15-,17+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291176 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ncc(cc2n1)C1CCOCC1 |r| Show InChI InChI=1S/C25H30N6O2/c1-16-10-19(26)15-31(14-16)24-4-7-27-13-23(24)30-25(32)21-3-2-20-22(29-21)11-18(12-28-20)17-5-8-33-9-6-17/h2-4,7,11-13,16-17,19H,5-6,8-10,14-15,26H2,1H3,(H,30,32)/t16-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291176 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ncc(cc2n1)C1CCOCC1 |r| Show InChI InChI=1S/C25H30N6O2/c1-16-10-19(26)15-31(14-16)24-4-7-27-13-23(24)30-25(32)21-3-2-20-22(29-21)11-18(12-28-20)17-5-8-33-9-6-17/h2-4,7,11-13,16-17,19H,5-6,8-10,14-15,26H2,1H3,(H,30,32)/t16-,19+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291182 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES COc1cc(F)c(c(F)c1)-c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H26F2N6O2/c1-15-7-17(30)14-35(13-15)25-5-6-31-12-24(25)34-27(36)22-4-3-21-23(33-22)8-16(11-32-21)26-19(28)9-18(37-2)10-20(26)29/h3-6,8-12,15,17H,7,13-14,30H2,1-2H3,(H,34,36)/t15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291182 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES COc1cc(F)c(c(F)c1)-c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H26F2N6O2/c1-15-7-17(30)14-35(13-15)25-5-6-31-12-24(25)34-27(36)22-4-3-21-23(33-22)8-16(11-32-21)26-19(28)9-18(37-2)10-20(26)29/h3-6,8-12,15,17H,7,13-14,30H2,1-2H3,(H,34,36)/t15-,17+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291183 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES CCn1cc(cn1)-c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C25H28N8O/c1-3-33-14-18(11-29-33)17-9-22-20(28-10-17)4-5-21(30-22)25(34)31-23-12-27-7-6-24(23)32-13-16(2)8-19(26)15-32/h4-7,9-12,14,16,19H,3,8,13,15,26H2,1-2H3,(H,31,34)/t16-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291183 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES CCn1cc(cn1)-c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C25H28N8O/c1-3-33-14-18(11-29-33)17-9-22-20(28-10-17)4-5-21(30-22)25(34)31-23-12-27-7-6-24(23)32-13-16(2)8-19(26)15-32/h4-7,9-12,14,16,19H,3,8,13,15,26H2,1-2H3,(H,31,34)/t16-,19+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291184 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CC(C)c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C23H28N6O2/c1-13(2)15-8-19-17(26-9-15)4-5-18(27-19)23(31)28-20-10-25-7-6-21(20)29-11-14(3)22(30)16(24)12-29/h4-10,13-14,16,22,30H,11-12,24H2,1-3H3,(H,28,31)/t14-,16+,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291184 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CC(C)c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C23H28N6O2/c1-13(2)15-8-19-17(26-9-15)4-5-18(27-19)23(31)28-20-10-25-7-6-21(20)29-11-14(3)22(30)16(24)12-29/h4-10,13-14,16,22,30H,11-12,24H2,1-3H3,(H,28,31)/t14-,16+,22+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291185 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES COc1ccc(cn1)-c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C26H27N7O3/c1-15-13-33(14-18(27)25(15)34)23-7-8-28-12-22(23)32-26(35)20-5-4-19-21(31-20)9-17(11-29-19)16-3-6-24(36-2)30-10-16/h3-12,15,18,25,34H,13-14,27H2,1-2H3,(H,32,35)/t15-,18+,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291185 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES COc1ccc(cn1)-c1cnc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C26H27N7O3/c1-15-13-33(14-18(27)25(15)34)23-7-8-28-12-22(23)32-26(35)20-5-4-19-21(31-20)9-17(11-29-19)16-3-6-24(36-2)30-10-16/h3-12,15,18,25,34H,13-14,27H2,1-2H3,(H,32,35)/t15-,18+,25+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291186 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ncc(cc2n1)N1CCOCC1 |r| Show InChI InChI=1S/C24H29N7O3/c1-15-13-31(14-17(25)23(15)32)22-4-5-26-12-21(22)29-24(33)19-3-2-18-20(28-19)10-16(11-27-18)30-6-8-34-9-7-30/h2-5,10-12,15,17,23,32H,6-9,13-14,25H2,1H3,(H,29,33)/t15-,17+,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291186 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ncc(cc2n1)N1CCOCC1 |r| Show InChI InChI=1S/C24H29N7O3/c1-15-13-31(14-17(25)23(15)32)22-4-5-26-12-21(22)29-24(33)19-3-2-18-20(28-19)10-16(11-27-18)30-6-8-34-9-7-30/h2-5,10-12,15,17,23,32H,6-9,13-14,25H2,1H3,(H,29,33)/t15-,17+,23+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291187 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CCc1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C23H27N5O2/c1-3-15-4-5-16-6-7-18(26-19(16)10-15)23(30)27-20-11-25-9-8-21(20)28-12-14(2)22(29)17(24)13-28/h4-11,14,17,22,29H,3,12-13,24H2,1-2H3,(H,27,30)/t14-,17+,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291187 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CCc1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C23H27N5O2/c1-3-15-4-5-16-6-7-18(26-19(16)10-15)23(30)27-20-11-25-9-8-21(20)28-12-14(2)22(29)17(24)13-28/h4-11,14,17,22,29H,3,12-13,24H2,1-2H3,(H,27,30)/t14-,17+,22+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291189 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CC(C)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C24H29N5O2/c1-14(2)17-5-4-16-6-7-19(27-20(16)10-17)24(31)28-21-11-26-9-8-22(21)29-12-15(3)23(30)18(25)13-29/h4-11,14-15,18,23,30H,12-13,25H2,1-3H3,(H,28,31)/t15-,18+,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291189 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CC(C)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C24H29N5O2/c1-14(2)17-5-4-16-6-7-19(27-20(16)10-17)24(31)28-21-11-26-9-8-22(21)29-12-15(3)23(30)18(25)13-29/h4-11,14-15,18,23,30H,12-13,25H2,1-3H3,(H,28,31)/t15-,18+,23+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291190 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)C1CCOCC1 |r| Show InChI InChI=1S/C26H31N5O3/c1-16-14-31(15-20(27)25(16)32)24-6-9-28-13-23(24)30-26(33)21-5-4-18-2-3-19(12-22(18)29-21)17-7-10-34-11-8-17/h2-6,9,12-13,16-17,20,25,32H,7-8,10-11,14-15,27H2,1H3,(H,30,33)/t16-,20+,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291190 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)C1CCOCC1 |r| Show InChI InChI=1S/C26H31N5O3/c1-16-14-31(15-20(27)25(16)32)24-6-9-28-13-23(24)30-26(33)21-5-4-18-2-3-19(12-22(18)29-21)17-7-10-34-11-8-17/h2-6,9,12-13,16-17,20,25,32H,7-8,10-11,14-15,27H2,1H3,(H,30,33)/t16-,20+,25+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291191 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCOCC1 |r| Show InChI InChI=1S/C25H30N6O3/c1-16-14-31(15-19(26)24(16)32)23-6-7-27-13-22(23)29-25(33)20-5-3-17-2-4-18(12-21(17)28-20)30-8-10-34-11-9-30/h2-7,12-13,16,19,24,32H,8-11,14-15,26H2,1H3,(H,29,33)/t16-,19+,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291191 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCOCC1 |r| Show InChI InChI=1S/C25H30N6O3/c1-16-14-31(15-19(26)24(16)32)23-6-7-27-13-22(23)29-25(33)20-5-3-17-2-4-18(12-21(17)28-20)30-8-10-34-11-9-30/h2-7,12-13,16,19,24,32H,8-11,14-15,26H2,1H3,(H,29,33)/t16-,19+,24+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291193 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCOCC1 |r| Show InChI InChI=1S/C25H30N6O2/c1-17-12-19(26)16-31(15-17)24-6-7-27-14-23(24)29-25(32)21-5-3-18-2-4-20(13-22(18)28-21)30-8-10-33-11-9-30/h2-7,13-14,17,19H,8-12,15-16,26H2,1H3,(H,29,32)/t17-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291193 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCOCC1 |r| Show InChI InChI=1S/C25H30N6O2/c1-17-12-19(26)16-31(15-17)24-6-7-27-14-23(24)29-25(32)21-5-3-18-2-4-20(13-22(18)28-21)30-8-10-33-11-9-30/h2-7,13-14,17,19H,8-12,15-16,26H2,1H3,(H,29,32)/t17-,19+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291194 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC2(CCOCC2)CC1 |r| Show InChI InChI=1S/C30H38N6O3/c1-20-18-36(19-23(31)28(20)37)27-6-11-32-17-26(27)34-29(38)24-5-3-21-2-4-22(16-25(21)33-24)35-12-7-30(8-13-35)9-14-39-15-10-30/h2-6,11,16-17,20,23,28,37H,7-10,12-15,18-19,31H2,1H3,(H,34,38)/t20-,23+,28+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291194 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC2(CCOCC2)CC1 |r| Show InChI InChI=1S/C30H38N6O3/c1-20-18-36(19-23(31)28(20)37)27-6-11-32-17-26(27)34-29(38)24-5-3-21-2-4-22(16-25(21)33-24)35-12-7-30(8-13-35)9-14-39-15-10-30/h2-6,11,16-17,20,23,28,37H,7-10,12-15,18-19,31H2,1H3,(H,34,38)/t20-,23+,28+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291195 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC2(CCOCC2)CC1 |r| Show InChI InChI=1S/C30H38N6O2/c1-21-16-23(31)20-36(19-21)28-6-11-32-18-27(28)34-29(37)25-5-3-22-2-4-24(17-26(22)33-25)35-12-7-30(8-13-35)9-14-38-15-10-30/h2-6,11,17-18,21,23H,7-10,12-16,19-20,31H2,1H3,(H,34,37)/t21-,23+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291195 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC2(CCOCC2)CC1 |r| Show InChI InChI=1S/C30H38N6O2/c1-21-16-23(31)20-36(19-21)28-6-11-32-18-27(28)34-29(37)25-5-3-22-2-4-24(17-26(22)33-25)35-12-7-30(8-13-35)9-14-38-15-10-30/h2-6,11,17-18,21,23H,7-10,12-16,19-20,31H2,1H3,(H,34,37)/t21-,23+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291196 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)C#N |r| Show InChI InChI=1S/C27H31N7O2/c1-17-15-34(16-21(29)26(17)35)25-6-9-30-14-24(25)32-27(36)22-5-3-19-2-4-20(12-23(19)31-22)33-10-7-18(13-28)8-11-33/h2-6,9,12,14,17-18,21,26,35H,7-8,10-11,15-16,29H2,1H3,(H,32,36)/t17-,21+,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291196 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)C#N |r| Show InChI InChI=1S/C27H31N7O2/c1-17-15-34(16-21(29)26(17)35)25-6-9-30-14-24(25)32-27(36)22-5-3-19-2-4-20(12-23(19)31-22)33-10-7-18(13-28)8-11-33/h2-6,9,12,14,17-18,21,26,35H,7-8,10-11,15-16,29H2,1H3,(H,32,36)/t17-,21+,26+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291197 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)C#N |r| Show InChI InChI=1S/C27H31N7O/c1-18-12-21(29)17-34(16-18)26-6-9-30-15-25(26)32-27(35)23-5-3-20-2-4-22(13-24(20)31-23)33-10-7-19(14-28)8-11-33/h2-6,9,13,15,18-19,21H,7-8,10-12,16-17,29H2,1H3,(H,32,35)/t18-,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291197 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)C#N |r| Show InChI InChI=1S/C27H31N7O/c1-18-12-21(29)17-34(16-18)26-6-9-30-15-25(26)32-27(35)23-5-3-20-2-4-22(13-24(20)31-23)33-10-7-19(14-28)8-11-33/h2-6,9,13,15,18-19,21H,7-8,10-12,16-17,29H2,1H3,(H,32,35)/t18-,21+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291198 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCN(C)CC1 |r| Show InChI InChI=1S/C26H33N7O2/c1-17-15-33(16-20(27)25(17)34)24-7-8-28-14-23(24)30-26(35)21-6-4-18-3-5-19(13-22(18)29-21)32-11-9-31(2)10-12-32/h3-8,13-14,17,20,25,34H,9-12,15-16,27H2,1-2H3,(H,30,35)/t17-,20+,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291198 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCN(C)CC1 |r| Show InChI InChI=1S/C26H33N7O2/c1-17-15-33(16-20(27)25(17)34)24-7-8-28-14-23(24)30-26(35)21-6-4-18-3-5-19(13-22(18)29-21)32-11-9-31(2)10-12-32/h3-8,13-14,17,20,25,34H,9-12,15-16,27H2,1-2H3,(H,30,35)/t17-,20+,25+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291199 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCN(C)CC1 |r| Show InChI InChI=1S/C26H33N7O/c1-18-13-20(27)17-33(16-18)25-7-8-28-15-24(25)30-26(34)22-6-4-19-3-5-21(14-23(19)29-22)32-11-9-31(2)10-12-32/h3-8,14-15,18,20H,9-13,16-17,27H2,1-2H3,(H,30,34)/t18-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291199 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCN(C)CC1 |r| Show InChI InChI=1S/C26H33N7O/c1-18-13-20(27)17-33(16-18)25-7-8-28-15-24(25)30-26(34)22-6-4-19-3-5-21(14-23(19)29-22)32-11-9-31(2)10-12-32/h3-8,14-15,18,20H,9-13,16-17,27H2,1-2H3,(H,30,34)/t18-,20+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291200 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)c1ccncc1 |r| Show InChI InChI=1S/C31H35N7O2/c1-20-18-38(19-25(32)30(20)39)29-8-13-34-17-28(29)36-31(40)26-5-3-23-2-4-24(16-27(23)35-26)37-14-9-22(10-15-37)21-6-11-33-12-7-21/h2-8,11-13,16-17,20,22,25,30,39H,9-10,14-15,18-19,32H2,1H3,(H,36,40)/t20-,25+,30+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291200 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES C[C@H]1CN(C[C@@H](N)[C@@H]1O)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)c1ccncc1 |r| Show InChI InChI=1S/C31H35N7O2/c1-20-18-38(19-25(32)30(20)39)29-8-13-34-17-28(29)36-31(40)26-5-3-23-2-4-24(16-27(23)35-26)37-14-9-22(10-15-37)21-6-11-33-12-7-21/h2-8,11-13,16-17,20,22,25,30,39H,9-10,14-15,18-19,32H2,1H3,(H,36,40)/t20-,25+,30+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291201 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)c1ccncc1 |r| Show InChI InChI=1S/C31H35N7O/c1-21-16-25(32)20-38(19-21)30-8-13-34-18-29(30)36-31(39)27-5-3-24-2-4-26(17-28(24)35-27)37-14-9-23(10-15-37)22-6-11-33-12-7-22/h2-8,11-13,17-18,21,23,25H,9-10,14-16,19-20,32H2,1H3,(H,36,39)/t21-,25+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291201 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES C[C@@H]1C[C@H](N)CN(C1)c1ccncc1NC(=O)c1ccc2ccc(cc2n1)N1CCC(CC1)c1ccncc1 |r| Show InChI InChI=1S/C31H35N7O/c1-21-16-25(32)20-38(19-21)30-8-13-34-18-29(30)36-31(39)27-5-3-24-2-4-26(17-28(24)35-27)37-14-9-23(10-15-37)22-6-11-33-12-7-22/h2-8,11-13,17-18,21,23,25H,9-10,14-16,19-20,32H2,1H3,(H,36,39)/t21-,25+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291202 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CCN1CCN(CC1=O)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C27H33N7O3/c1-3-32-10-11-33(16-25(32)35)19-6-4-18-5-7-21(30-22(18)12-19)27(37)31-23-13-29-9-8-24(23)34-14-17(2)26(36)20(28)15-34/h4-9,12-13,17,20,26,36H,3,10-11,14-16,28H2,1-2H3,(H,31,37)/t17-,20+,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291202 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES CCN1CCN(CC1=O)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C27H33N7O3/c1-3-32-10-11-33(16-25(32)35)19-6-4-18-5-7-21(30-22(18)12-19)27(37)31-23-13-29-9-8-24(23)34-14-17(2)26(36)20(28)15-34/h4-9,12-13,17,20,26,36H,3,10-11,14-16,28H2,1-2H3,(H,31,37)/t17-,20+,26+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291203 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES CCN1CCN(CC1=O)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H33N7O2/c1-3-32-10-11-33(17-26(32)35)21-6-4-19-5-7-22(30-23(19)13-21)27(36)31-24-14-29-9-8-25(24)34-15-18(2)12-20(28)16-34/h4-9,13-14,18,20H,3,10-12,15-17,28H2,1-2H3,(H,31,36)/t18-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291203 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES CCN1CCN(CC1=O)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H33N7O2/c1-3-32-10-11-33(17-26(32)35)21-6-4-19-5-7-22(30-23(19)13-21)27(36)31-24-14-29-9-8-25(24)34-15-18(2)12-20(28)16-34/h4-9,13-14,18,20H,3,10-12,15-17,28H2,1-2H3,(H,31,36)/t18-,20+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291204 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES COC1CCN(CC1)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C27H34N6O3/c1-17-15-33(16-21(28)26(17)34)25-7-10-29-14-24(25)31-27(35)22-6-4-18-3-5-19(13-23(18)30-22)32-11-8-20(36-2)9-12-32/h3-7,10,13-14,17,20-21,26,34H,8-9,11-12,15-16,28H2,1-2H3,(H,31,35)/t17-,21+,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291204 (N-{4-[(3R,4R,5S)-3-Amino-4-hydroxy-5-methylpiperid...) Show SMILES COC1CCN(CC1)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)[C@@H](O)[C@H](N)C1 |r| Show InChI InChI=1S/C27H34N6O3/c1-17-15-33(16-21(28)26(17)34)25-7-10-29-14-24(25)31-27(35)22-6-4-18-3-5-19(13-23(18)30-22)32-11-8-20(36-2)9-12-32/h3-7,10,13-14,17,20-21,26,34H,8-9,11-12,15-16,28H2,1-2H3,(H,31,35)/t17-,21+,26+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM291205 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES COC1CCN(CC1)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H34N6O2/c1-18-13-20(28)17-33(16-18)26-7-10-29-15-25(26)31-27(34)23-6-4-19-3-5-21(14-24(19)30-23)32-11-8-22(35-2)9-12-32/h3-7,10,14-15,18,20,22H,8-9,11-13,16-17,28H2,1-2H3,(H,31,34)/t18-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM291205 (N-{4-[(3S,5R)-3-Amino-5-methylpiperidin-1-yl]pyrid...) Show SMILES COC1CCN(CC1)c1ccc2ccc(nc2c1)C(=O)Nc1cnccc1N1C[C@H](C)C[C@H](N)C1 |r| Show InChI InChI=1S/C27H34N6O2/c1-18-13-20(28)17-33(16-18)26-7-10-29-15-25(26)31-27(34)23-6-4-19-3-5-21(14-24(19)30-23)32-11-8-22(35-2)9-12-32/h3-7,10,14-15,18,20,22H,8-9,11-13,16-17,28H2,1-2H3,(H,31,34)/t18-,20+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bryn Mawr College					Assay Description Pim-1 and Pim-3 kinase assays-20 uL reactions were run in white 384 well polystyrene plates dotted with 0.8 uL compound/DMSO in the assay buffer (50 ...				J Med Chem 51: 4968-77 (2008) BindingDB Entry DOI: 10.7270/Q2ZC856W
					More data for this Ligand-Target Pair

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