Found 21 hits Enz. Inhib. hit(s) with all data for entry = 50029569 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285678
((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)Show SMILES CC(C)(O)c1ccc(CC[C@@H](SCC2(CC(O)=O)CC2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)cc1 Show InChI InChI=1S/C33H33Cl2NO3S2/c1-32(2,39)24-10-6-21(7-11-24)9-14-26(40-20-33(16-17-33)19-28(37)38)23-5-3-4-22(18-23)8-12-25-13-15-27-30(36-25)29(34)31(35)41-27/h3-8,10-13,15,18,26,39H,9,14,16-17,19-20H2,1-2H3,(H,37,38)/b12-8+/t26-/m1/s1 | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285677
((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)Show SMILES OC(=O)CC1(CS[C@H](CCc2cccc(c2)C2(O)CCC2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C34H33Cl2NO3S2/c35-30-31-28(42-32(30)36)13-11-26(37-31)10-8-22-4-1-6-24(18-22)27(41-21-33(16-17-33)20-29(38)39)12-9-23-5-2-7-25(19-23)34(40)14-3-15-34/h1-2,4-8,10-11,13,18-19,27,40H,3,9,12,14-17,20-21H2,(H,38,39)/b10-8+/t27-/m1/s1 | PDB
Reactome pathway
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PC cid
PC sid
UniChem
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| Article
| n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285683
((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sc(Cl)c(Cl)c3n2)c1 Show InChI InChI=1S/C33H33Cl2NO3S2/c1-32(2,39)25-9-4-3-7-22(25)11-14-26(40-20-33(16-17-33)19-28(37)38)23-8-5-6-21(18-23)10-12-24-13-15-27-30(36-24)29(34)31(35)41-27/h3-10,12-13,15,18,26,39H,11,14,16-17,19-20H2,1-2H3,(H,37,38)/b12-10+/t26-/m1/s1 | PDB
Reactome pathway
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PC sid
UniChem
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| Article
| n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285675
((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccc(cc2)C2(O)CCC2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C34H33Cl2NO3S2/c35-30-31-28(42-32(30)36)14-12-26(37-31)11-7-23-3-1-4-24(19-23)27(41-21-33(17-18-33)20-29(38)39)13-8-22-5-9-25(10-6-22)34(40)15-2-16-34/h1,3-7,9-12,14,19,27,40H,2,8,13,15-18,20-21H2,(H,38,39)/b11-7+/t27-/m1/s1 | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285671
(CHEMBL86063 | {1-[(R)-1-{3-[(E)-2-(2,3-Dichloro-th...)Show SMILES OCc1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sc(Cl)c(Cl)c3n2)c1 Show InChI InChI=1S/C31H29Cl2NO3S2/c32-28-29-26(39-30(28)33)13-11-24(34-29)10-8-20-4-3-7-22(16-20)25(38-19-31(14-15-31)17-27(36)37)12-9-21-5-1-2-6-23(21)18-35/h1-8,10-11,13,16,25,35H,9,12,14-15,17-19H2,(H,36,37)/b10-8+/t25-/m1/s1 | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.720 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285674
((1-{(R)-1-{3-[(E)-2-(2,3-Difluoro-thieno[3,2-b]pyr...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sc(F)c(F)c3n2)c1 Show InChI InChI=1S/C33H33F2NO3S2/c1-32(2,39)25-9-4-3-7-22(25)11-14-26(40-20-33(16-17-33)19-28(37)38)23-8-5-6-21(18-23)10-12-24-13-15-27-30(36-24)29(34)31(35)41-27/h3-10,12-13,15,18,26,39H,11,14,16-17,19-20H2,1-2H3,(H,37,38)/b12-10+/t26-/m1/s1 | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285670
((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccccc2C2(O)CCC2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C34H33Cl2NO3S2/c35-30-31-28(42-32(30)36)14-12-25(37-31)11-9-22-5-3-7-24(19-22)27(41-21-33(17-18-33)20-29(38)39)13-10-23-6-1-2-8-26(23)34(40)15-4-16-34/h1-3,5-9,11-12,14,19,27,40H,4,10,13,15-18,20-21H2,(H,38,39)/b11-9+/t27-/m1/s1 | PDB
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.05 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285672
((1-{(R)-1-{3-[2-(2,3-Dichloro-thieno[3,2-b]pyridin...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(CCc2ccc3sc(Cl)c(Cl)c3n2)c1 Show InChI InChI=1S/C33H35Cl2NO3S2/c1-32(2,39)25-9-4-3-7-22(25)11-14-26(40-20-33(16-17-33)19-28(37)38)23-8-5-6-21(18-23)10-12-24-13-15-27-30(36-24)29(34)31(35)41-27/h3-9,13,15,18,26,39H,10-12,14,16-17,19-20H2,1-2H3,(H,37,38)/t26-/m1/s1 | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 1.06 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285673
((1-{(R)-1-{3-[(E)-2-(2-Chloro-thieno[3,2-b]pyridin...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sc(Cl)cc3n2)c1 Show InChI InChI=1S/C33H34ClNO3S2/c1-32(2,38)26-9-4-3-7-23(26)11-14-28(39-21-33(16-17-33)20-31(36)37)24-8-5-6-22(18-24)10-12-25-13-15-29-27(35-25)19-30(34)40-29/h3-10,12-13,15,18-19,28,38H,11,14,16-17,20-21H2,1-2H3,(H,36,37)/b12-10+/t28-/m1/s1 | PDB
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PC sid
UniChem
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| Article
| n/a | n/a | 1.16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285676
(CHEMBL86302 | [1-((R)-1-{3-[(E)-2-(2,3-Dichloro-th...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccccc2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C30H27Cl2NO2S2/c31-27-28-25(37-29(27)32)14-12-23(33-28)11-9-21-7-4-8-22(17-21)24(13-10-20-5-2-1-3-6-20)36-19-30(15-16-30)18-26(34)35/h1-9,11-12,14,17,24H,10,13,15-16,18-19H2,(H,34,35)/b11-9+/t24-/m1/s1 | PDB
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PC sid
UniChem
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| Article
| n/a | n/a | 1.63 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285682
((1-{(R)-1-{3-[(E)-2-(3-Chloro-thieno[3,2-b]pyridin...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3scc(Cl)c3n2)c1 Show InChI InChI=1S/C33H34ClNO3S2/c1-32(2,38)26-9-4-3-7-23(26)11-14-28(40-21-33(16-17-33)19-30(36)37)24-8-5-6-22(18-24)10-12-25-13-15-29-31(35-25)27(34)20-39-29/h3-10,12-13,15,18,20,28,38H,11,14,16-17,19,21H2,1-2H3,(H,36,37)/b12-10+/t28-/m1/s1 | PDB
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PC sid
UniChem
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| Article
| n/a | n/a | 1.91 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285680
((1-{(R)-1-[3-(2,3-Dichloro-thieno[3,2-b]pyridin-5-...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(OCc2ccc3sc(Cl)c(Cl)c3n2)c1 Show InChI InChI=1S/C32H33Cl2NO4S2/c1-31(2,38)24-9-4-3-6-20(24)10-12-25(40-19-32(14-15-32)17-27(36)37)21-7-5-8-23(16-21)39-18-22-11-13-26-29(35-22)28(33)30(34)41-26/h3-9,11,13,16,25,38H,10,12,14-15,17-19H2,1-2H3,(H,36,37)/t25-/m1/s1 | PDB
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PC cid
PC sid
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| Article
| n/a | n/a | 2.01 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285686
(CHEMBL87696 | {1-[(R)-1-{3-[(E)-2-(2,3-Dichloro-th...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccc(F)cc2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C30H26Cl2FNO2S2/c31-27-28-25(38-29(27)32)13-11-23(34-28)10-6-20-2-1-3-21(16-20)24(12-7-19-4-8-22(33)9-5-19)37-18-30(14-15-30)17-26(35)36/h1-6,8-11,13,16,24H,7,12,14-15,17-18H2,(H,35,36)/b10-6+/t24-/m1/s1 | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285679
(CHEMBL85572 | [1-((R)-3-(2-Bromo-phenyl)-1-{3-[(E)...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccccc2Br)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C30H26BrCl2NO2S2/c31-23-7-2-1-5-20(23)9-12-24(37-18-30(14-15-30)17-26(35)36)21-6-3-4-19(16-21)8-10-22-11-13-25-28(34-22)27(32)29(33)38-25/h1-8,10-11,13,16,24H,9,12,14-15,17-18H2,(H,35,36)/b10-8+/t24-/m1/s1 | PDB
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PC sid
UniChem
Similars
| Article
| n/a | n/a | 2.43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285685
(CHEMBL87528 | {1-[(R)-1-{3-[(E)-2-(2,3-Dichloro-th...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccccc2C(F)(F)F)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C31H26Cl2F3NO2S2/c32-27-28-25(41-29(27)33)13-11-22(37-28)10-8-19-4-3-6-21(16-19)24(40-18-30(14-15-30)17-26(38)39)12-9-20-5-1-2-7-23(20)31(34,35)36/h1-8,10-11,13,16,24H,9,12,14-15,17-18H2,(H,38,39)/b10-8+/t24-/m1/s1 | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285681
(CHEMBL82790 | [1-((R)-3-(4-Bromo-phenyl)-1-{3-[(E)...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccc(Br)cc2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C30H26BrCl2NO2S2/c31-22-8-4-19(5-9-22)7-12-24(37-18-30(14-15-30)17-26(35)36)21-3-1-2-20(16-21)6-10-23-11-13-25-28(34-23)27(32)29(33)38-25/h1-6,8-11,13,16,24H,7,12,14-15,17-18H2,(H,35,36)/b10-6+/t24-/m1/s1 | PDB
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UniChem
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| Article
| n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285688
((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccccc2C(O)(C(F)(F)F)C(F)(F)F)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C33H27Cl2F6NO3S2/c34-27-28-25(47-29(27)35)13-11-22(42-28)10-8-19-4-3-6-21(16-19)24(46-18-30(14-15-30)17-26(43)44)12-9-20-5-1-2-7-23(20)31(45,32(36,37)38)33(39,40)41/h1-8,10-11,13,16,24,45H,9,12,14-15,17-18H2,(H,43,44)/b10-8+/t24-/m1/s1 | PDB
Reactome pathway
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TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285684
((1-{(R)-3-[2-(1-Hydroxy-1-methyl-ethyl)-phenyl]-1-...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sccc3n2)c1 Show InChI InChI=1S/C33H35NO3S2/c1-32(2,37)27-9-4-3-7-24(27)11-14-29(39-22-33(17-18-33)21-31(35)36)25-8-5-6-23(20-25)10-12-26-13-15-30-28(34-26)16-19-38-30/h3-10,12-13,15-16,19-20,29,37H,11,14,17-18,21-22H2,1-2H3,(H,35,36)/b12-10+/t29-/m1/s1 | PDB
Reactome pathway
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| n/a | n/a | 8.49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285669
(CHEMBL84841 | {1-[(R)-1-{3-[(E)-2-(2,3-Dichloro-th...)Show SMILES OC(=O)CC1(CS[C@H](CCc2ccc(cc2)C(F)(F)F)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C31H26Cl2F3NO2S2/c32-27-28-25(41-29(27)33)13-11-23(37-28)10-6-20-2-1-3-21(16-20)24(40-18-30(14-15-30)17-26(38)39)12-7-19-4-8-22(9-5-19)31(34,35)36/h1-6,8-11,13,16,24H,7,12,14-15,17-18H2,(H,38,39)/b10-6+/t24-/m1/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.67 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285689
((1-{(R)-1-{3-[2-(2,3-Dichloro-thieno[3,2-b]pyridin...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(c1)C1CC1c1ccc2sc(Cl)c(Cl)c2n1 Show InChI InChI=1S/C34H35Cl2NO3S2/c1-33(2,40)25-9-4-3-6-20(25)10-12-27(41-19-34(14-15-34)18-29(38)39)22-8-5-7-21(16-22)23-17-24(23)26-11-13-28-31(37-26)30(35)32(36)42-28/h3-9,11,13,16,23-24,27,40H,10,12,14-15,17-19H2,1-2H3,(H,38,39)/t23?,24?,27-/m1/s1 | PDB
Reactome pathway
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UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
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| Article
| n/a | n/a | 15.7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50285687
((1-{(R)-1-[3-(2,3-Dichloro-thieno[3,2-b]pyridin-5-...)Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(COc2ccc3sc(Cl)c(Cl)c3n2)c1 Show InChI InChI=1S/C32H33Cl2NO4S2/c1-31(2,38)23-9-4-3-7-21(23)10-11-24(40-19-32(14-15-32)17-27(36)37)22-8-5-6-20(16-22)18-39-26-13-12-25-29(35-26)28(33)30(34)41-25/h3-9,12-13,16,24,38H,10-11,14-15,17-19H2,1-2H3,(H,36,37)/t24-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | >150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes |
Bioorg Med Chem Lett 5: 2551-2556 (1995)
Article DOI: 10.1016/0960-894X(95)00448-3
BindingDB Entry DOI: 10.7270/Q2W37W8Q |
More data for this
Ligand-Target Pair | |
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