Found 228 hits Enz. Inhib. hit(s) with all data for entry = 50047911 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50196924
(CHEMBL3960774)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Cl)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50196924
(CHEMBL3960774)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Cl)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197048
(CHEMBL3975687)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Br)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11BrN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197048
(CHEMBL3975687)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Br)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11BrN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 363 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197057
(CHEMBL3974720)Show SMILES Cc1ccc(cc1)S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-2-4-7(5-3-6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197057
(CHEMBL3974720)Show SMILES Cc1ccc(cc1)S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-2-4-7(5-3-6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197046
(CHEMBL3939524)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C16H16N2O6S/c17-13(15(19)20)14(16(21)22)18-25(23,24)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14,18H,17H2,(H,19,20)(H,21,22)/t13-,14?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197046
(CHEMBL3939524)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C16H16N2O6S/c17-13(15(19)20)14(16(21)22)18-25(23,24)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14,18H,17H2,(H,19,20)(H,21,22)/t13-,14?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197054
(CHEMBL3937517)Show SMILES N[C@@H]([C@H](NS(=O)(=O)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H12N2O6S/c11-7(9(13)14)8(10(15)16)12-19(17,18)6-4-2-1-3-5-6/h1-5,7-8,12H,11H2,(H,13,14)(H,15,16)/t7-,8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197026
(CHEMBL3909952)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(F)c(F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H10F2N2O6S/c11-5-2-1-4(3-6(5)12)21(19,20)14-8(10(17)18)7(13)9(15)16/h1-3,7-8,14H,13H2,(H,15,16)(H,17,18)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197054
(CHEMBL3937517)Show SMILES N[C@@H]([C@H](NS(=O)(=O)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H12N2O6S/c11-7(9(13)14)8(10(15)16)12-19(17,18)6-4-2-1-3-5-6/h1-5,7-8,12H,11H2,(H,13,14)(H,15,16)/t7-,8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197026
(CHEMBL3909952)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(F)c(F)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H10F2N2O6S/c11-5-2-1-4(3-6(5)12)21(19,20)14-8(10(17)18)7(13)9(15)16/h1-3,7-8,14H,13H2,(H,15,16)(H,17,18)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50093753
((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)Show InChI InChI=1S/C11H13NO5/c12-8(10(13)14)9(11(15)16)17-6-7-4-2-1-3-5-7/h1-5,8-9H,6,12H2,(H,13,14)(H,15,16)/t8-,9-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 955 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50093753
((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)Show InChI InChI=1S/C11H13NO5/c12-8(10(13)14)9(11(15)16)17-6-7-4-2-1-3-5-7/h1-5,8-9H,6,12H2,(H,13,14)(H,15,16)/t8-,9-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50196924
(CHEMBL3960774)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Cl)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 977 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50196924
(CHEMBL3960774)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Cl)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197054
(CHEMBL3937517)Show SMILES N[C@@H]([C@H](NS(=O)(=O)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H12N2O6S/c11-7(9(13)14)8(10(15)16)12-19(17,18)6-4-2-1-3-5-6/h1-5,7-8,12H,11H2,(H,13,14)(H,15,16)/t7-,8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197054
(CHEMBL3937517)Show SMILES N[C@@H]([C@H](NS(=O)(=O)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H12N2O6S/c11-7(9(13)14)8(10(15)16)12-19(17,18)6-4-2-1-3-5-6/h1-5,7-8,12H,11H2,(H,13,14)(H,15,16)/t7-,8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50093753
((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)Show InChI InChI=1S/C11H13NO5/c12-8(10(13)14)9(11(15)16)17-6-7-4-2-1-3-5-7/h1-5,8-9H,6,12H2,(H,13,14)(H,15,16)/t8-,9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197031
(CHEMBL3983719)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(F)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11FN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50093753
((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)Show InChI InChI=1S/C11H13NO5/c12-8(10(13)14)9(11(15)16)17-6-7-4-2-1-3-5-7/h1-5,8-9H,6,12H2,(H,13,14)(H,15,16)/t8-,9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197031
(CHEMBL3983719)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(F)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11FN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197015
(CHEMBL3920012)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccccc1Cl)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-3-1-2-4-6(5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197015
(CHEMBL3920012)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccccc1Cl)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-3-1-2-4-6(5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197057
(CHEMBL3974720)Show SMILES Cc1ccc(cc1)S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-2-4-7(5-3-6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197032
(CHEMBL3955047)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H12N2O6S/c11-7(9(13)14)8(10(15)16)12-19(17,18)6-4-2-1-3-5-6/h1-5,7-8,12H,11H2,(H,13,14)(H,15,16)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197057
(CHEMBL3974720)Show SMILES Cc1ccc(cc1)S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-2-4-7(5-3-6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197032
(CHEMBL3955047)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H12N2O6S/c11-7(9(13)14)8(10(15)16)12-19(17,18)6-4-2-1-3-5-6/h1-5,7-8,12H,11H2,(H,13,14)(H,15,16)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197031
(CHEMBL3983719)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(F)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11FN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197031
(CHEMBL3983719)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(F)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11FN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197046
(CHEMBL3939524)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C16H16N2O6S/c17-13(15(19)20)14(16(21)22)18-25(23,24)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14,18H,17H2,(H,19,20)(H,21,22)/t13-,14?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197046
(CHEMBL3939524)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C16H16N2O6S/c17-13(15(19)20)14(16(21)22)18-25(23,24)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14,18H,17H2,(H,19,20)(H,21,22)/t13-,14?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197041
(CHEMBL3948303)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(N)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H13N3O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,11-12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197041
(CHEMBL3948303)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(N)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H13N3O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,11-12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197054
(CHEMBL3937517)Show SMILES N[C@@H]([C@H](NS(=O)(=O)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H12N2O6S/c11-7(9(13)14)8(10(15)16)12-19(17,18)6-4-2-1-3-5-6/h1-5,7-8,12H,11H2,(H,13,14)(H,15,16)/t7-,8-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197054
(CHEMBL3937517)Show SMILES N[C@@H]([C@H](NS(=O)(=O)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H12N2O6S/c11-7(9(13)14)8(10(15)16)12-19(17,18)6-4-2-1-3-5-6/h1-5,7-8,12H,11H2,(H,13,14)(H,15,16)/t7-,8-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197050
(CHEMBL3920886)Show SMILES N[C@@H](C(NS(=O)(=O)c1cc(F)c(F)cc1F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H9F3N2O6S/c11-3-1-5(13)6(2-4(3)12)22(20,21)15-8(10(18)19)7(14)9(16)17/h1-2,7-8,15H,14H2,(H,16,17)(H,18,19)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50197050
(CHEMBL3920886)Show SMILES N[C@@H](C(NS(=O)(=O)c1cc(F)c(F)cc1F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H9F3N2O6S/c11-3-1-5(13)6(2-4(3)12)22(20,21)15-8(10(18)19)7(14)9(16)17/h1-2,7-8,15H,14H2,(H,16,17)(H,18,19)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197048
(CHEMBL3975687)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Br)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11BrN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197048
(CHEMBL3975687)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Br)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11BrN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197029
(CHEMBL3950379)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(Cl)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-2-1-3-6(4-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197029
(CHEMBL3950379)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(Cl)c1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-2-1-3-6(4-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50196927
(CHEMBL3938810)Show SMILES Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-4-2-3-5-7(6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 1
(Homo sapiens (Human)) | BDBM50196927
(CHEMBL3938810)Show SMILES Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-4-2-3-5-7(6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197040
(CHEMBL3894651)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H11F3N2O6S/c12-11(13,14)5-2-1-3-6(4-5)23(21,22)16-8(10(19)20)7(15)9(17)18/h1-4,7-8,16H,15H2,(H,17,18)(H,19,20)/t7-,8?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50197040
(CHEMBL3894651)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H11F3N2O6S/c12-11(13,14)5-2-1-3-6(4-5)23(21,22)16-8(10(19)20)7(15)9(17)18/h1-4,7-8,16H,15H2,(H,17,18)(H,19,20)/t7-,8?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197041
(CHEMBL3948303)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(N)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H13N3O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,11-12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197041
(CHEMBL3948303)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(N)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H13N3O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,11-12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 2
(Homo sapiens (Human)) | BDBM50196924
(CHEMBL3960774)Show SMILES N[C@@H](C(NS(=O)(=O)c1ccc(Cl)cc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C10H11ClN2O6S/c11-5-1-3-6(4-2-5)20(18,19)13-8(10(16)17)7(12)9(14)15/h1-4,7-8,13H,12H2,(H,14,15)(H,16,17)/t7-,8?/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197028
(CHEMBL3899726)Show SMILES N[C@@H](C(NS(=O)(=O)c1cccs1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C8H10N2O6S2/c9-5(7(11)12)6(8(13)14)10-18(15,16)4-2-1-3-17-4/h1-3,5-6,10H,9H2,(H,11,12)(H,13,14)/t5-,6?/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method |
J Med Chem 59: 8771-8786 (2016)
Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C |
More data for this Ligand-Target Pair | |