Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238298 (1-(3-aminophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 55 | -41.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238299 (1-(3-azidophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 64 | -41.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238298 (1-(3-aminophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 108 | -39.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238299 (1-(3-azidophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 129 | -39.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238300 (4-benzoyl-1-(3-((2-hydroxy-4-oxopent-2-en-3-yl) di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 160 | -38.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238302 (4-benzoyl-1-(3-((3-hydroxy-1-oxo-1-phenylbut-2-en-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 166 | -38.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238301 (4-benzoyl-1-(3-nitrophenyl)-5-phenyl-N-(4-sulfamoy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 215 | -38.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238301 (4-benzoyl-1-(3-nitrophenyl)-5-phenyl-N-(4-sulfamoy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 337 | -36.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238302 (4-benzoyl-1-(3-((3-hydroxy-1-oxo-1-phenylbut-2-en-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 521 | -35.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238300 (4-benzoyl-1-(3-((2-hydroxy-4-oxopent-2-en-3-yl) di...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 595 | -35.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238304 (4-benzoyl-1-(3-(2-(1,3-dioxo-1,3-diphenylpropan-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.95E+3 | -32.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238303 (Ethyl-2-(2-(3-(4-benzoyl-5-phenyl-3-(4-sulfamoylph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.90E+3 | -31.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM238304 (4-benzoyl-1-(3-(2-(1,3-dioxo-1,3-diphenylpropan-2-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.10E+3 | -30.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238303 (Ethyl-2-(2-(3-(4-benzoyl-5-phenyl-3-(4-sulfamoylph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.24E+3 | -29.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o... | J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ | |||||||||||
More data for this Ligand-Target Pair |