Compile Data Set for Download or QSAR

Found 210 hits of ic50 for UniProtKB: P00747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290292 (2-Oxo-4-(piperidin-4-yl)-1,2-dihydropyrimido[1,2-b...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(C#N)c3c2[nH]1 Show InChI InChI=1S/C16H15N5O/c17-9-11-2-1-3-12-15(11)16-19-14(22)8-13(21(16)20-12)10-4-6-18-7-5-10/h1-3,8,10,18H,4-7H2,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290292 (2-Oxo-4-(piperidin-4-yl)-1,2-dihydropyrimido[1,2-b...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(C#N)c3c2[nH]1 Show InChI InChI=1S/C16H15N5O/c17-9-11-2-1-3-12-15(11)16-19-14(22)8-13(21(16)20-12)10-4-6-18-7-5-10/h1-3,8,10,18H,4-7H2,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290334 (9-Fluoro-10-phenyl-4-(piperidin-4-yl)pyrimido[1,2-...) Show SMILES Fc1ccc2nn3c(cc(=O)[nH]c3c2c1-c1ccccc1)C1CCNCC1 Show InChI InChI=1S/C21H19FN4O/c22-15-6-7-16-20(19(15)14-4-2-1-3-5-14)21-24-18(27)12-17(26(21)25-16)13-8-10-23-11-9-13/h1-7,12-13,23H,8-11H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290336 (10-Chloro-8-methyl-4-(piperidin-4-yl)pyrimido[1,2-...) Show SMILES Cc1cc(Cl)c2c(c1)nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C16H17ClN4O/c1-9-6-11(17)15-12(7-9)20-21-13(8-14(22)19-16(15)21)10-2-4-18-5-3-10/h6-8,10,18H,2-5H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290334 (9-Fluoro-10-phenyl-4-(piperidin-4-yl)pyrimido[1,2-...) Show SMILES Fc1ccc2nn3c(cc(=O)[nH]c3c2c1-c1ccccc1)C1CCNCC1 Show InChI InChI=1S/C21H19FN4O/c22-15-6-7-16-20(19(15)14-4-2-1-3-5-14)21-24-18(27)12-17(26(21)25-16)13-8-10-23-11-9-13/h1-7,12-13,23H,8-11H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290336 (10-Chloro-8-methyl-4-(piperidin-4-yl)pyrimido[1,2-...) Show SMILES Cc1cc(Cl)c2c(c1)nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C16H17ClN4O/c1-9-6-11(17)15-12(7-9)20-21-13(8-14(22)19-16(15)21)10-2-4-18-5-3-10/h6-8,10,18H,2-5H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290286 (7-Bromo-4-(piperidin-4-yl)pyrido[4′,3′...) Show SMILES Brc1cncc2c1nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C14H14BrN5O/c15-10-7-17-6-9-13(10)19-20-11(5-12(21)18-14(9)20)8-1-3-16-4-2-8/h5-8,16H,1-4H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290309 ((−)-trans-10-Ethoxy-4-(2-methylpiperidin-4-y...) Show SMILES CCOc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNC(C)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290314 (10-(2-Fluorophenyl)-4-(piperidin-4-yl)pyrimido[1,2...) Show SMILES Fc1ccccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C21H19FN4O/c22-16-6-2-1-4-14(16)15-5-3-7-17-20(15)21-24-19(27)12-18(26(21)25-17)13-8-10-23-11-9-13/h1-7,12-13,23H,8-11H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290320 (10-Cyclopentyl-4-(piperidin-4-yl)pyrimido[1,2-b]in...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(C4CCCC4)c3c2[nH]1 Show InChI InChI=1S/C20H24N4O/c25-18-12-17(14-8-10-21-11-9-14)24-20(22-18)19-15(13-4-1-2-5-13)6-3-7-16(19)23-24/h3,6-7,12-14,21H,1-2,4-5,8-11H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290324 (4-(Piperidin-4-yl)-10-[2-(trifluoromethyl)phenyl]p...) Show SMILES FC(F)(F)c1ccccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C22H19F3N4O/c23-22(24,25)16-6-2-1-4-14(16)15-5-3-7-17-20(15)21-27-19(30)12-18(29(21)28-17)13-8-10-26-11-9-13/h1-7,12-13,26H,8-11H2,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290286 (7-Bromo-4-(piperidin-4-yl)pyrido[4′,3′...) Show SMILES Brc1cncc2c1nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C14H14BrN5O/c15-10-7-17-6-9-13(10)19-20-11(5-12(21)18-14(9)20)8-1-3-16-4-2-8/h5-8,16H,1-4H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290309 ((−)-trans-10-Ethoxy-4-(2-methylpiperidin-4-y...) Show SMILES CCOc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNC(C)C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290314 (10-(2-Fluorophenyl)-4-(piperidin-4-yl)pyrimido[1,2...) Show SMILES Fc1ccccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C21H19FN4O/c22-16-6-2-1-4-14(16)15-5-3-7-17-20(15)21-24-19(27)12-18(26(21)25-17)13-8-10-23-11-9-13/h1-7,12-13,23H,8-11H2,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290320 (10-Cyclopentyl-4-(piperidin-4-yl)pyrimido[1,2-b]in...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(C4CCCC4)c3c2[nH]1 Show InChI InChI=1S/C20H24N4O/c25-18-12-17(14-8-10-21-11-9-14)24-20(22-18)19-15(13-4-1-2-5-13)6-3-7-16(19)23-24/h3,6-7,12-14,21H,1-2,4-5,8-11H2,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290324 (4-(Piperidin-4-yl)-10-[2-(trifluoromethyl)phenyl]p...) Show SMILES FC(F)(F)c1ccccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C22H19F3N4O/c23-22(24,25)16-6-2-1-4-14(16)15-5-3-7-17-20(15)21-27-19(30)12-18(29(21)28-17)13-8-10-26-11-9-13/h1-7,12-13,26H,8-11H2,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290307 ((−)-trans-10-Bromo-4-(2-methylpiperidin-4-yl...) Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c3c(Br)cccc3nn12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290312 (4-(Piperidin-4-yl)-10-[4-(trifluoromethyl)phenyl]p...) Show SMILES FC(F)(F)c1ccc(cc1)-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C22H19F3N4O/c23-22(24,25)15-6-4-13(5-7-15)16-2-1-3-17-20(16)21-27-19(30)12-18(29(21)28-17)14-8-10-26-11-9-14/h1-7,12,14,26H,8-11H2,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290313 (10-Phenyl-4-(piperidin-4-yl)pyrimido[1,2-b]indazol...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(-c4ccccc4)c3c2[nH]1 Show InChI InChI=1S/C21H20N4O/c26-19-13-18(15-9-11-22-12-10-15)25-21(23-19)20-16(7-4-8-17(20)24-25)14-5-2-1-3-6-14/h1-8,13,15,22H,9-12H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290269 (10-Bromo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-...) Show SMILES Brc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C15H15BrN4O/c16-10-2-1-3-11-14(10)15-18-13(21)8-12(20(15)19-11)9-4-6-17-7-5-9/h1-3,8-9,17H,4-7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290329 (10-sec-Butyl-4-(piperidin-4-yl)pyrimido[1,2-b]inda...) Show SMILES CCC(C)c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290307 ((−)-trans-10-Bromo-4-(2-methylpiperidin-4-yl...) Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c3c(Br)cccc3nn12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290312 (4-(Piperidin-4-yl)-10-[4-(trifluoromethyl)phenyl]p...) Show SMILES FC(F)(F)c1ccc(cc1)-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C22H19F3N4O/c23-22(24,25)15-6-4-13(5-7-15)16-2-1-3-17-20(16)21-27-19(30)12-18(29(21)28-17)14-8-10-26-11-9-14/h1-7,12,14,26H,8-11H2,(H,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290313 (10-Phenyl-4-(piperidin-4-yl)pyrimido[1,2-b]indazol...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(-c4ccccc4)c3c2[nH]1 Show InChI InChI=1S/C21H20N4O/c26-19-13-18(15-9-11-22-12-10-15)25-21(23-19)20-16(7-4-8-17(20)24-25)14-5-2-1-3-6-14/h1-8,13,15,22H,9-12H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290269 (10-Bromo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-...) Show SMILES Brc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C15H15BrN4O/c16-10-2-1-3-11-14(10)15-18-13(21)8-12(20(15)19-11)9-4-6-17-7-5-9/h1-3,8-9,17H,4-7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290329 (10-sec-Butyl-4-(piperidin-4-yl)pyrimido[1,2-b]inda...) Show SMILES CCC(C)c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290308 ((−)-trans-4-(2-Methylpiperidin-4-yl)-10-phen...) Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c3c(ccnc3nn12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290343 (10-(1-Methyl-1H-pyrazol-5-yl)-4-(piperidin-4-yl)py...) Show SMILES Cn1nccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C19H20N6O/c1-24-15(7-10-21-24)13-3-2-4-14-18(13)19-22-17(26)11-16(25(19)23-14)12-5-8-20-9-6-12/h2-4,7,10-12,20H,5-6,8-9H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290315 (4-(Piperidin-4-yl)-10-(pyridin-3-yl)pyrimido[1,2-b...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(-c4cccnc4)c3c2[nH]1 Show InChI InChI=1S/C20H19N5O/c26-18-11-17(13-6-9-21-10-7-13)25-20(23-18)19-15(4-1-5-16(19)24-25)14-3-2-8-22-12-14/h1-5,8,11-13,21H,6-7,9-10H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290262 (10-Chloro-4-(piperidin-4-yl)pyrimido[1,2-b]indazol...) Show SMILES Clc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C15H15ClN4O/c16-10-2-1-3-11-14(10)15-18-13(21)8-12(20(15)19-11)9-4-6-17-7-5-9/h1-3,8-9,17H,4-7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290328 (10-Bromo-7-fluoro-4-(piperidin-4-yl)pyrimido[1,2-b...) Show SMILES Fc1ccc(Br)c2c1nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C15H14BrFN4O/c16-9-1-2-10(17)14-13(9)15-19-12(22)7-11(21(15)20-14)8-3-5-18-6-4-8/h1-2,7-8,18H,3-6H2,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290331 (10-Bromo-9-methyl-4-(piperidin-4-yl)pyrimido[1,2-b...) Show SMILES Cc1ccc2nn3c(cc(=O)[nH]c3c2c1Br)C1CCNCC1 Show InChI InChI=1S/C16H17BrN4O/c1-9-2-3-11-14(15(9)17)16-19-13(22)8-12(21(16)20-11)10-4-6-18-7-5-10/h2-3,8,10,18H,4-7H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290333 (10-Isopropoxy-4-(piperidin-4-yl)pyrimido[1,2-b]ind...) Show SMILES CC(C)Oc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C18H22N4O2/c1-11(2)24-15-5-3-4-13-17(15)18-20-16(23)10-14(22(18)21-13)12-6-8-19-9-7-12/h3-5,10-12,19H,6-9H2,1-2H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290335 (10-(2,6-Difluorophenyl)-4-(piperidin-4-yl)pyrimido...) Show SMILES Fc1cccc(F)c1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 |(1.55,5.36,;2.64,4.27,;4.13,4.67,;5.22,3.58,;4.82,2.09,;3.33,1.69,;2.93,.21,;2.24,2.78,;.7,2.78,;.08,4.19,;-1.46,4.35,;-2.36,3.1,;-1.73,1.7,;-2.36,.29,;-1.22,-.74,;-1.22,-2.28,;.12,-3.05,;1.45,-2.28,;2.78,-3.05,;1.45,-.74,;.12,.03,;-.2,1.54,;-2.55,-3.05,;-3.88,-2.28,;-5.22,-3.05,;-5.22,-4.59,;-3.88,-5.36,;-2.55,-4.59,)| Show InChI InChI=1S/C21H18F2N4O/c22-14-4-2-5-15(23)19(14)13-3-1-6-16-20(13)21-25-18(28)11-17(27(21)26-16)12-7-9-24-10-8-12/h1-6,11-12,24H,7-10H2,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290343 (10-(1-Methyl-1H-pyrazol-5-yl)-4-(piperidin-4-yl)py...) Show SMILES Cn1nccc1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C19H20N6O/c1-24-15(7-10-21-24)13-3-2-4-14-18(13)19-22-17(26)11-16(25(19)23-14)12-5-8-20-9-6-12/h2-4,7,10-12,20H,5-6,8-9H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290308 ((−)-trans-4-(2-Methylpiperidin-4-yl)-10-phen...) Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c3c(ccnc3nn12)-c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290311 (10-(4-Methoxyphenyl)-4-(piperidin-4-yl)pyrimido[1,...) Show SMILES COc1ccc(cc1)-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C22H22N4O2/c1-28-16-7-5-14(6-8-16)17-3-2-4-18-21(17)22-24-20(27)13-19(26(22)25-18)15-9-11-23-12-10-15/h2-8,13,15,23H,9-12H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290315 (4-(Piperidin-4-yl)-10-(pyridin-3-yl)pyrimido[1,2-b...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(-c4cccnc4)c3c2[nH]1 Show InChI InChI=1S/C20H19N5O/c26-18-11-17(13-6-9-21-10-7-13)25-20(23-18)19-15(4-1-5-16(19)24-25)14-3-2-8-22-12-14/h1-5,8,11-13,21H,6-7,9-10H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290262 (10-Chloro-4-(piperidin-4-yl)pyrimido[1,2-b]indazol...) Show SMILES Clc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C15H15ClN4O/c16-10-2-1-3-11-14(10)15-18-13(21)8-12(20(15)19-11)9-4-6-17-7-5-9/h1-3,8-9,17H,4-7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290328 (10-Bromo-7-fluoro-4-(piperidin-4-yl)pyrimido[1,2-b...) Show SMILES Fc1ccc(Br)c2c1nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C15H14BrFN4O/c16-9-1-2-10(17)14-13(9)15-19-12(22)7-11(21(15)20-14)8-3-5-18-6-4-8/h1-2,7-8,18H,3-6H2,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290331 (10-Bromo-9-methyl-4-(piperidin-4-yl)pyrimido[1,2-b...) Show SMILES Cc1ccc2nn3c(cc(=O)[nH]c3c2c1Br)C1CCNCC1 Show InChI InChI=1S/C16H17BrN4O/c1-9-2-3-11-14(15(9)17)16-19-13(22)8-12(21(16)20-11)10-4-6-18-7-5-10/h2-3,8,10,18H,4-7H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290333 (10-Isopropoxy-4-(piperidin-4-yl)pyrimido[1,2-b]ind...) Show SMILES CC(C)Oc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C18H22N4O2/c1-11(2)24-15-5-3-4-13-17(15)18-20-16(23)10-14(22(18)21-13)12-6-8-19-9-7-12/h3-5,10-12,19H,6-9H2,1-2H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290335 (10-(2,6-Difluorophenyl)-4-(piperidin-4-yl)pyrimido...) Show SMILES Fc1cccc(F)c1-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 |(1.55,5.36,;2.64,4.27,;4.13,4.67,;5.22,3.58,;4.82,2.09,;3.33,1.69,;2.93,.21,;2.24,2.78,;.7,2.78,;.08,4.19,;-1.46,4.35,;-2.36,3.1,;-1.73,1.7,;-2.36,.29,;-1.22,-.74,;-1.22,-2.28,;.12,-3.05,;1.45,-2.28,;2.78,-3.05,;1.45,-.74,;.12,.03,;-.2,1.54,;-2.55,-3.05,;-3.88,-2.28,;-5.22,-3.05,;-5.22,-4.59,;-3.88,-5.36,;-2.55,-4.59,)| Show InChI InChI=1S/C21H18F2N4O/c22-14-4-2-5-15(23)19(14)13-3-1-6-16-20(13)21-25-18(28)11-17(27(21)26-16)12-7-9-24-10-8-12/h1-6,11-12,24H,7-10H2,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290311 (10-(4-Methoxyphenyl)-4-(piperidin-4-yl)pyrimido[1,...) Show SMILES COc1ccc(cc1)-c1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C22H22N4O2/c1-28-16-7-5-14(6-8-16)17-3-2-4-18-21(17)22-24-20(27)13-19(26(22)25-18)15-9-11-23-12-10-15/h2-8,13,15,23H,9-12H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290316 (4-(Piperidin-4-yl)-10-(pyridin-4-yl)pyrimido[1,2-b...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(-c4ccncc4)c3c2[nH]1 Show InChI InChI=1S/C20H19N5O/c26-18-12-17(14-6-10-22-11-7-14)25-20(23-18)19-15(2-1-3-16(19)24-25)13-4-8-21-9-5-13/h1-5,8-9,12,14,22H,6-7,10-11H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290332 (10-Bromo-7-methyl-4-(piperidin-4-yl)pyrimido[1,2-b...) Show SMILES Cc1ccc(Br)c2c1nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C16H17BrN4O/c1-9-2-3-11(17)14-15(9)20-21-12(8-13(22)19-16(14)21)10-4-6-18-7-5-10/h2-3,8,10,18H,4-7H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290338 (10-Bromo-8-fluoro-4-(piperidin-4-yl)pyrimido[1,2-b...) Show SMILES Fc1cc(Br)c2c(c1)nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C15H14BrFN4O/c16-10-5-9(17)6-11-14(10)15-19-13(22)7-12(21(15)20-11)8-1-3-18-4-2-8/h5-8,18H,1-4H2,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290316 (4-(Piperidin-4-yl)-10-(pyridin-4-yl)pyrimido[1,2-b...) Show SMILES O=c1cc(C2CCNCC2)n2nc3cccc(-c4ccncc4)c3c2[nH]1 Show InChI InChI=1S/C20H19N5O/c26-18-12-17(14-6-10-22-11-7-14)25-20(23-18)19-15(2-1-3-16(19)24-25)13-4-8-21-9-5-13/h1-5,8-9,12,14,22H,6-7,10-11H2,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290332 (10-Bromo-7-methyl-4-(piperidin-4-yl)pyrimido[1,2-b...) Show SMILES Cc1ccc(Br)c2c1nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C16H17BrN4O/c1-9-2-3-11(17)14-15(9)20-21-12(8-13(22)19-16(14)21)10-4-6-18-7-5-10/h2-3,8,10,18H,4-7H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290338 (10-Bromo-8-fluoro-4-(piperidin-4-yl)pyrimido[1,2-b...) Show SMILES Fc1cc(Br)c2c(c1)nn1c(cc(=O)[nH]c21)C1CCNCC1 Show InChI InChI=1S/C15H14BrFN4O/c16-10-5-9(17)6-11-14(10)15-19-13(22)7-12(21(15)20-11)8-1-3-18-4-2-8/h5-8,18H,1-4H2,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair

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