Compile Data Set for Download or QSAR

Found 1230 hits of ic50 for UniProtKB: P35351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (RAT)	BDBM50030726 (3-[4-(2'-Benzoylsulfamoyl-3-fluoro-biphenyl-4-ylme...) Show SMILES CCCNC(=O)c1ccc(c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)c1=O)C(F)(F)F Show InChI InChI=1S/C36H33F4N5O5S/c1-3-10-32-42-45(30-21-25(33(46)41-19-4-2)17-18-28(30)36(38,39)40)35(48)44(32)22-26-16-15-24(20-29(26)37)27-13-8-9-14-31(27)51(49,50)43-34(47)23-11-6-5-7-12-23/h5-9,11-18,20-21H,3-4,10,19,22H2,1-2H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0530	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50282708 (CHEMBL289472 | Thiophene-2-carboxylic acid benzyl-...) Show SMILES CCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(Cc1ccccc1)C(=O)c1cccs1 Show InChI InChI=1S/C36H29N7O2S/c1-2-33-37-31-19-18-27(42(22-24-9-4-3-5-10-24)36(45)32-13-8-20-46-32)21-30(31)35(44)43(33)23-25-14-16-26(17-15-25)28-11-6-7-12-29(28)34-38-40-41-39-34/h3-21H,2,22-23H2,1H3,(H,38,39,40,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125 I]Sar1Ile8-AII from AT2 receptor of rat midbrain membrane				Bioorg Med Chem Lett 4: 1479-1484 (1994) Article DOI: 10.1016/S0960-894X(01)80517-5 BindingDB Entry DOI: 10.7270/Q2BC401G
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030685 (CHEMBL338888 | Pentanoic acid {4-chloro-3-[3-ethyl...) Show SMILES CCCCC(=O)Nc1ccc(Cl)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C33H37ClFN5O6S/c1-6-8-13-30(41)36-23-16-17-25(34)27(19-23)40-32(43)39(29(7-2)37-40)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030721 (4-Bromo-N-butyl-3-{4-[2'-(2,5-dichloro-benzoylsulf...) Show SMILES CCCCNC(=O)c1ccc(Br)c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2cc(Cl)ccc2Cl)c1=O Show InChI InChI=1S/C36H33BrCl2FN5O5S/c1-3-5-17-41-34(46)23-13-15-28(37)31(19-23)45-36(48)44(33(42-45)8-4-2)21-24-12-11-22(18-30(24)40)26-9-6-7-10-32(26)51(49,50)43-35(47)27-20-25(38)14-16-29(27)39/h6-7,9-16,18-20H,3-5,8,17,21H2,1-2H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0920	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283765 (CHEMBL321313 | N-{3-[3-Butyl-4-(3-fluoro-2'-(ethyl...) Show SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)OCC Show InChI InChI=1S/C33H37ClFN5O6S/c1-5-8-10-31-37-40(29-19-25(36-21(4)41)14-15-27(29)34)33(43)39(31)20-24-13-12-23(18-28(24)35)26-17-22(9-6-2)11-16-30(26)47(44,45)38-32(42)46-7-3/h11-19H,5-10,20H2,1-4H3,(H,36,41)(H,38,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT2 receptor from rat midbrain				Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030693 (CHEMBL338687 | Pentanoic acid {4-bromo-3-[3-ethyl-...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)C)c1=O Show InChI InChI=1S/C32H35BrFN5O6S/c1-5-7-12-30(40)35-23-15-16-25(33)27(18-23)39-32(42)38(29(6-2)36-39)19-22-14-13-21(17-26(22)34)24-10-8-9-11-28(24)46(43,44)37-31(41)45-20(3)4/h8-11,13-18,20H,5-7,12,19H2,1-4H3,(H,35,40)(H,37,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50032358 (CHEMBL430659 | isopentyloxy 2-[2-(4-{4-ethyl-5-[3-...) Show SMILES CCCc1nc(CC)c(C(=O)CCN(C(=O)c2ccncc2)c2ccccc2)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C42H46FN5O6S/c1-5-12-39-45-36(6-2)40(37(49)21-25-47(33-13-8-7-9-14-33)41(50)30-19-23-44-24-20-30)48(39)28-32-18-17-31(27-35(32)43)34-15-10-11-16-38(34)55(52,53)46-42(51)54-26-22-29(3)4/h7-11,13-20,23-24,27,29H,5-6,12,21-22,25-26,28H2,1-4H3,(H,46,51)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of [125I]-[Sar1,Ile8]Ang II binding at rat angiotensin II (type 2) receptor.				J Med Chem 38: 2938-45 (1995) BindingDB Entry DOI: 10.7270/Q2639NRN
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM50030815 (CHEMBL404594) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)[C@@H](C)CC)C(O)=O |wU:8.7,25.27,wD:41.44,4.4,15.16,29.31,45.48,2.2,62.65,(8.44,-18.06,;9.36,-17.24,;9.05,-15.73,;7.88,-15.34,;10.19,-14.7,;9.88,-13.19,;11.03,-12.16,;12.2,-12.55,;10.71,-10.66,;11.74,-9.51,;10.97,-8.18,;9.46,-8.5,;9.33,-10.02,;7.99,-10.79,;7.99,-12.02,;6.66,-10.02,;5.32,-10.79,;5.32,-12.33,;4.07,-13.22,;4.55,-14.68,;6.09,-14.68,;6.56,-13.21,;6.66,-8.48,;5.33,-7.71,;4.43,-8.22,;5.33,-6.17,;3.99,-5.39,;4,-3.85,;5.06,-3.24,;2.66,-3.08,;1.33,-3.85,;-.01,-3.08,;-1.34,-3.84,;-2.67,-3.07,;-2.67,-1.53,;-3.73,-.91,;-1.33,-.76,;,-1.54,;2.67,-1.54,;4,-.77,;5.07,-1.39,;4.01,.77,;5.35,1.53,;5.36,3.07,;4.29,3.69,;6.69,3.84,;6.7,5.37,;8.04,6.14,;8.04,7.68,;9.38,8.44,;9.39,9.99,;10.45,10.6,;8.32,10.61,;8.03,3.06,;8.02,1.52,;6.94,.91,;9.35,.74,;9.34,-.8,;10.22,-1.32,;2.68,1.54,;1.61,.93,;2.69,2.78,;6.66,-5.4,;7.73,-6.01,;6.66,-3.86,;7.73,-3.24,;11.66,-15.17,;11.91,-16.38,;12.58,-14.35,)| Show InChI InChI=1S/C46H73N13O10/c1-8-26(5)37(43(66)55-33(21-29-22-50-24-52-29)44(67)59-19-11-13-34(59)41(64)58-38(45(68)69)27(6)9-2)57-40(63)32(20-28-14-16-30(60)17-15-28)54-42(65)36(25(3)4)56-39(62)31(53-35(61)23-49-7)12-10-18-51-46(47)48/h14-17,22,24-27,31-34,36-38,49,60H,8-13,18-21,23H2,1-7H3,(H,50,52)(H,53,61)(H,54,65)(H,55,66)(H,56,62)(H,57,63)(H,58,64)(H,68,69)(H4,47,48,51)/t26-,27-,31-,32-,33-,34-,36-,37-,38-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Warner Lambert Company Curated by ChEMBL					Assay Description Binding affinity for rat brain Angiotensin II receptor				J Med Chem 34: 3248-60 (1991) BindingDB Entry DOI: 10.7270/Q24X5B06
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50011972 (CHEMBL385189 | Sar-Arg-Val-Tyr-Ile-His-Pro-Thi-OH) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cccs1)C(O)=O Show InChI InChI=1S/C47H69N13O10S/c1-6-27(4)39(44(67)56-34(21-29-23-51-25-53-29)45(68)60-18-8-12-36(60)42(65)57-35(46(69)70)22-31-10-9-19-71-31)59-41(64)33(20-28-13-15-30(61)16-14-28)55-43(66)38(26(2)3)58-40(63)32(54-37(62)24-50-5)11-7-17-52-47(48)49/h9-10,13-16,19,23,25-27,32-36,38-39,50,61H,6-8,11-12,17-18,20-22,24H2,1-5H3,(H,51,53)(H,54,62)(H,55,66)(H,56,67)(H,57,65)(H,58,63)(H,59,64)(H,69,70)(H4,48,49,52)/t27-,32-,33-,34-,35-,36-,38-,39-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of [125I]-AII specific binding towards angiotensin II receptor in rat mesenteric membranes.				J Med Chem 34: 1514-7 (1991) BindingDB Entry DOI: 10.7270/Q2TD9WBV
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283763 (CHEMBL321531 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...) Show SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C37H36Cl2FN5O5S/c1-4-6-12-35-42-45(33-21-27(41-23(3)46)16-17-31(33)39)37(48)44(35)22-26-15-14-25(20-32(26)40)29-19-24(9-5-2)13-18-34(29)51(49,50)43-36(47)28-10-7-8-11-30(28)38/h7-8,10-11,13-21H,4-6,9,12,22H2,1-3H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against AT1 receptor from rat adrenal tissues				Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030711 (CHEMBL338027 | L-163958 | Pentanoic acid {4-bromo-...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C33H37BrFN5O6S/c1-6-8-13-30(41)36-23-16-17-25(34)27(19-23)40-32(43)39(29(7-2)37-40)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030700 (CHEMBL436396 | N-{4-Bromo-3-[4-(3-fluoro-2'-(N-t-b...) Show SMILES CCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C32H35BrFN5O6S/c1-6-10-28-36-39(26-18-22(15-16-24(26)33)35-29(40)7-2)31(42)38(28)19-21-14-13-20(17-25(21)34)23-11-8-9-12-27(23)46(43,44)37-30(41)45-32(3,4)5/h8-9,11-18H,6-7,10,19H2,1-5H3,(H,35,40)(H,37,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030720 (CHEMBL122158 | N-{3-[4-(3-Fluoro-2'-(N-t-butyloxyc...) Show SMILES CCCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C37H35F4N5O6S/c1-5-11-32-43-46(30-21-26(18-19-28(30)37(39,40)41)42-33(47)23-12-7-6-8-13-23)35(49)45(32)22-25-17-16-24(20-29(25)38)27-14-9-10-15-31(27)53(50,51)44-34(48)52-36(2,3)4/h6-10,12-21H,5,11,22H2,1-4H3,(H,42,47)(H,44,48)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283766 (CHEMBL313868 | N-(3-{3-Butyl-4-[3-fluoro-2'-(2-flu...) Show SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)c1ccccc1F Show InChI InChI=1S/C37H36ClF2N5O5S/c1-4-6-12-35-42-45(33-21-27(41-23(3)46)16-17-30(33)38)37(48)44(35)22-26-15-14-25(20-32(26)40)29-19-24(9-5-2)13-18-34(29)51(49,50)43-36(47)28-10-7-8-11-31(28)39/h7-8,10-11,13-21H,4-6,9,12,22H2,1-3H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT2 receptor from rat midbrain				Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283763 (CHEMBL321531 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...) Show SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C37H36Cl2FN5O5S/c1-4-6-12-35-42-45(33-21-27(41-23(3)46)16-17-31(33)39)37(48)44(35)22-26-15-14-25(20-32(26)40)29-19-24(9-5-2)13-18-34(29)51(49,50)43-36(47)28-10-7-8-11-30(28)38/h7-8,10-11,13-21H,4-6,9,12,22H2,1-3H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT2 receptor from rat midbrain				Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030687 (CHEMBL339256 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C36H32ClF4N5O5S/c1-3-5-14-32-43-46(30-20-24(42-33(47)4-2)17-18-27(30)36(39,40)41)35(49)45(32)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)52(50,51)44-34(48)26-11-6-8-12-28(26)37/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,42,47)(H,44,48)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50032368 (CHEMBL98047 | butyloxy 2-[2-(4-{4-ethyl-5-[3-pheny...) Show SMILES CCCC(=O)N(CCC(=O)c1c(CC)nc(CCC)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C)c1ccccc1 Show InChI InChI=1S/C40H49FN4O6S/c1-6-14-37-42-34(8-3)39(35(46)22-24-44(38(47)15-7-2)31-16-10-9-11-17-31)45(37)27-30-21-20-29(26-33(30)41)32-18-12-13-19-36(32)52(49,50)43-40(48)51-25-23-28(4)5/h9-13,16-21,26,28H,6-8,14-15,22-25,27H2,1-5H3,(H,43,48)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of [125I]-[Sar1,Ile8]Ang II binding at rat angiotensin II (type 2) receptor.				J Med Chem 38: 2938-45 (1995) BindingDB Entry DOI: 10.7270/Q2639NRN
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030691 (CHEMBL122380 | Pentanoic acid (4-bromo-3-{4-[2'-(2...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2cc(F)ccc2F)c1=O Show InChI InChI=1S/C35H31BrF3N5O5S/c1-3-5-10-33(45)40-24-14-15-27(36)30(19-24)44-35(47)43(32(4-2)41-44)20-22-12-11-21(17-29(22)39)25-8-6-7-9-31(25)50(48,49)42-34(46)26-18-23(37)13-16-28(26)38/h6-9,11-19H,3-5,10,20H2,1-2H3,(H,40,45)(H,42,46)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (RAT)	BDBM50230790 (CHEMBL292892) Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccc(cc1[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C23H23N3O6S/c1-2-3-6-21-24-13-18(10-17(23(29)30)11-19-5-4-9-33-19)25(21)14-16-8-7-15(22(27)28)12-20(16)26(31)32/h4-5,7-10,12-13H,2-3,6,11,14H2,1H3,(H,27,28)(H,29,30)/b17-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries				J Med Chem 36: 1880-92 (1993) BindingDB Entry DOI: 10.7270/Q2PK0JC7
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50032367 (CHEMBL317962 | isopentyloxy 2-[2-(4-{4-ethyl-5-[3-...) Show SMILES CCCc1nc(CC)c(C(=O)CCN(C(=O)c2cccnc2)c2ccccn2)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C41H45FN6O6S/c1-5-12-38-45-34(6-2)39(35(49)19-23-47(37-16-9-10-22-44-37)40(50)30-13-11-21-43-26-30)48(38)27-31-18-17-29(25-33(31)42)32-14-7-8-15-36(32)55(52,53)46-41(51)54-24-20-28(3)4/h7-11,13-18,21-22,25-26,28H,5-6,12,19-20,23-24,27H2,1-4H3,(H,46,51)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of [125I]-[Sar1,Ile8]Ang II binding at rat angiotensin II (type 2) receptor.				J Med Chem 38: 2938-45 (1995) BindingDB Entry DOI: 10.7270/Q2639NRN
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030707 (CHEMBL122273 | Pentanoic acid (4-bromo-3-{3-ethyl-...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2F)c1=O Show InChI InChI=1S/C35H32BrF2N5O5S/c1-3-5-14-33(44)39-24-17-18-27(36)30(20-24)43-35(46)42(32(4-2)40-43)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)49(47,48)41-34(45)26-11-6-8-12-28(26)37/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,39,44)(H,41,45)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030730 (CHEMBL341369 | Pentanoic acid {4-bromo-3-[4-(3-flu...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C34H39BrFN5O6S/c1-6-8-14-31(42)37-24-17-18-26(35)28(20-24)41-33(44)40(30(38-41)11-7-2)21-23-16-15-22(19-27(23)36)25-12-9-10-13-29(25)48(45,46)39-32(43)47-34(3,4)5/h9-10,12-13,15-20H,6-8,11,14,21H2,1-5H3,(H,37,42)(H,39,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030709 (CHEMBL338434 | Pentanoic acid {3-[3-butyl-4-(3-flu...) Show SMILES CCCCC(=O)Nc1ccc(c(c1)-n1nc(CCCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O)C(F)(F)F Show InChI InChI=1S/C36H41F4N5O6S/c1-6-8-14-31-42-45(29-21-25(41-32(46)15-9-7-2)18-19-27(29)36(38,39)40)34(48)44(31)22-24-17-16-23(20-28(24)37)26-12-10-11-13-30(26)52(49,50)43-33(47)51-35(3,4)5/h10-13,16-21H,6-9,14-15,22H2,1-5H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030732 (CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...) Show SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C35H41ClFN5O6S/c1-7-9-11-32-39-42(30-20-26(38-22(3)43)15-16-28(30)36)34(45)41(32)21-25-14-13-24(19-29(25)37)27-18-23(10-8-2)12-17-31(27)49(46,47)40-33(44)48-35(4,5)6/h12-20H,7-11,21H2,1-6H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against AT1 receptor from rat adrenal tissues.				Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030730 (CHEMBL341369 | Pentanoic acid {4-bromo-3-[4-(3-flu...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C34H39BrFN5O6S/c1-6-8-14-31(42)37-24-17-18-26(35)28(20-24)41-33(44)40(30(38-41)11-7-2)21-23-16-15-22(19-27(23)36)25-12-9-10-13-29(25)48(45,46)39-32(43)47-34(3,4)5/h9-10,12-13,15-20H,6-8,11,14,21H2,1-5H3,(H,37,42)(H,39,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030686 (CHEMBL338433 | N-{3-[3-Butyl-4-(3-fluoro-2'-(N-t-b...) Show SMILES CCCCc1nn(-c2cc(NC(=O)COCC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C35H39F4N5O7S/c1-6-8-13-30-41-44(28-19-24(40-31(45)21-50-7-2)16-17-26(28)35(37,38)39)33(47)43(30)20-23-15-14-22(18-27(23)36)25-11-9-10-12-29(25)52(48,49)42-32(46)51-34(3,4)5/h9-12,14-19H,6-8,13,20-21H2,1-5H3,(H,40,45)(H,42,46)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50032352 (CHEMBL98665 | butyloxy 2-[2-(4-{4-ethyl-5-[3-diphe...) Show SMILES CCCc1nc(CC)c(C(=O)CCN(C(=O)c2ccccc2)c2ccccc2)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C43H47FN4O6S/c1-5-15-40-45-37(6-2)41(38(49)24-26-47(34-18-11-8-12-19-34)42(50)31-16-9-7-10-17-31)48(40)29-33-23-22-32(28-36(33)44)35-20-13-14-21-39(35)55(52,53)46-43(51)54-27-25-30(3)4/h7-14,16-23,28,30H,5-6,15,24-27,29H2,1-4H3,(H,46,51)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of [125I]-[Sar1,Ile8]Ang II binding at rat angiotensin II (type 2) receptor.				J Med Chem 38: 2938-45 (1995) BindingDB Entry DOI: 10.7270/Q2639NRN
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030695 (CHEMBL340632 | N-Butyl-3-[3-butyl-4-(3-fluoro-2'-(...) Show SMILES CCCCNC(=O)c1ccc(Cl)c(c1)-n1nc(CCCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C35H41ClFN5O6S/c1-6-8-14-31-39-42(29-21-24(17-18-27(29)36)32(43)38-19-9-7-2)34(45)41(31)22-25-16-15-23(20-28(25)37)26-12-10-11-13-30(26)49(46,47)40-33(44)48-35(3,4)5/h10-13,15-18,20-21H,6-9,14,19,22H2,1-5H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50032352 (CHEMBL98665 | butyloxy 2-[2-(4-{4-ethyl-5-[3-diphe...) Show SMILES CCCc1nc(CC)c(C(=O)CCN(C(=O)c2ccccc2)c2ccccc2)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C43H47FN4O6S/c1-5-15-40-45-37(6-2)41(38(49)24-26-47(34-18-11-8-12-19-34)42(50)31-16-9-7-10-17-31)48(40)29-33-23-22-32(28-36(33)44)35-20-13-14-21-39(35)55(52,53)46-43(51)54-27-25-30(3)4/h7-14,16-23,28,30H,5-6,15,24-27,29H2,1-4H3,(H,46,51)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of [125I]-[Sar1,Ile8]Ang II binding at rat angiotensin II (type 2) receptor.				J Med Chem 38: 2938-45 (1995) BindingDB Entry DOI: 10.7270/Q2639NRN
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030693 (CHEMBL338687 | Pentanoic acid {4-bromo-3-[3-ethyl-...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)C)c1=O Show InChI InChI=1S/C32H35BrFN5O6S/c1-5-7-12-30(40)35-23-15-16-25(33)27(18-23)39-32(42)38(29(6-2)36-39)19-22-14-13-21(17-26(22)34)24-10-8-9-11-28(24)46(43,44)37-31(41)45-20(3)4/h8-11,13-18,20H,5-7,12,19H2,1-4H3,(H,35,40)(H,37,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030694 (CHEMBL273542 | N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2...) Show SMILES CCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C35H33BrFN5O6S/c1-5-31-39-42(29-20-25(17-18-27(29)36)38-32(43)22-11-7-6-8-12-22)34(45)41(31)21-24-16-15-23(19-28(24)37)26-13-9-10-14-30(26)49(46,47)40-33(44)48-35(2,3)4/h6-20H,5,21H2,1-4H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030726 (3-[4-(2'-Benzoylsulfamoyl-3-fluoro-biphenyl-4-ylme...) Show SMILES CCCNC(=O)c1ccc(c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)c1=O)C(F)(F)F Show InChI InChI=1S/C36H33F4N5O5S/c1-3-10-32-42-45(30-21-25(33(46)41-19-4-2)17-18-28(30)36(38,39)40)35(48)44(32)22-26-16-15-24(20-29(26)37)27-13-8-9-14-31(27)51(49,50)43-34(47)23-11-6-5-7-12-23/h5-9,11-18,20-21H,3-4,10,19,22H2,1-2H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030683 (CHEMBL121907 | N-Butyl-3-[4-(3-fluoro-2'-(N-t-buty...) Show SMILES CCCCNC(=O)c1ccc(c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O)C(F)(F)F Show InChI InChI=1S/C35H39F4N5O6S/c1-6-8-18-40-31(45)23-16-17-26(35(37,38)39)28(20-23)44-33(47)43(30(41-44)11-7-2)21-24-15-14-22(19-27(24)36)25-12-9-10-13-29(25)51(48,49)42-32(46)50-34(3,4)5/h9-10,12-17,19-20H,6-8,11,18,21H2,1-5H3,(H,40,45)(H,42,46)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283302 (2-ethyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonyla...) Show SMILES CCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C34H40FN5O6S/c1-7-31-37-29-15-14-25(36-33(42)39(6)22(4)5)19-27(29)32(41)40(31)20-24-13-12-23(18-28(24)35)26-10-8-9-11-30(26)47(44,45)38-34(43)46-17-16-21(2)3/h8-15,18-19,21-22H,7,16-17,20H2,1-6H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030720 (CHEMBL122158 | N-{3-[4-(3-Fluoro-2'-(N-t-butyloxyc...) Show SMILES CCCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C37H35F4N5O6S/c1-5-11-32-43-46(30-21-26(18-19-28(30)37(39,40)41)42-33(47)23-12-7-6-8-13-23)35(49)45(32)22-25-17-16-24(20-29(25)38)27-14-9-10-15-31(27)53(50,51)44-34(48)52-36(2,3)4/h6-10,12-21H,5,11,22H2,1-4H3,(H,42,47)(H,44,48)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030684 (CHEMBL339722 | N-{3-[3-Butyl-4-(3-fluoro-2-(N-t-bu...) Show SMILES CCCCc1nn(-c2cc(NC(=O)COCC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H39ClFN5O7S/c1-6-8-13-30-38-41(28-19-24(16-17-26(28)35)37-31(42)21-47-7-2)33(44)40(30)20-23-15-14-22(18-27(23)36)25-11-9-10-12-29(25)49(45,46)39-32(43)48-34(3,4)5/h9-12,14-19H,6-8,13,20-21H2,1-5H3,(H,37,42)(H,39,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283300 (2-Butyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonylam...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C36H44FN5O6S/c1-7-8-13-33-39-31-17-16-27(38-35(44)41(6)24(4)5)21-29(31)34(43)42(33)22-26-15-14-25(20-30(26)37)28-11-9-10-12-32(28)49(46,47)40-36(45)48-19-18-23(2)3/h9-12,14-17,20-21,23-24H,7-8,13,18-19,22H2,1-6H3,(H,38,44)(H,40,45)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283305 (3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...) Show SMILES CCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(CC)cc1F Show InChI InChI=1S/C37H37F2N5O5S/c1-5-9-34-42-32-17-15-26(41-37(47)40-22(3)4)20-29(32)36(46)44(34)21-25-14-13-24(19-30(25)38)27-10-7-8-11-33(27)50(48,49)43-35(45)28-16-12-23(6-2)18-31(28)39/h7-8,10-20,22H,5-6,9,21H2,1-4H3,(H,43,45)(H2,40,41,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283307 (4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...) Show SMILES CCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)COCC(C)C Show InChI InChI=1S/C34H40FN5O6S/c1-7-31-37-29-15-14-25(36-34(43)39(6)22(4)5)17-27(29)33(42)40(31)18-24-13-12-23(16-28(24)35)26-10-8-9-11-30(26)47(44,45)38-32(41)20-46-19-21(2)3/h8-17,21-22H,7,18-20H2,1-6H3,(H,36,43)(H,38,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030691 (CHEMBL122380 | Pentanoic acid (4-bromo-3-{4-[2'-(2...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2cc(F)ccc2F)c1=O Show InChI InChI=1S/C35H31BrF3N5O5S/c1-3-5-10-33(45)40-24-14-15-27(36)30(19-24)44-35(47)43(32(4-2)41-44)20-22-12-11-21(17-29(22)39)25-8-6-7-9-31(25)50(48,49)42-34(46)26-18-23(37)13-16-28(26)38/h6-9,11-19H,3-5,10,20H2,1-2H3,(H,40,45)(H,42,46)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030688 (CHEMBL122917 | N-(3-{3-Butyl-4-[2'-(3,3-dimethyl-b...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)CC(C)(C)C Show InChI InChI=1S/C35H39F4N5O5S/c1-6-8-13-30-41-44(28-19-24(40-31(45)7-2)16-17-26(28)35(37,38)39)33(47)43(30)21-23-15-14-22(18-27(23)36)25-11-9-10-12-29(25)50(48,49)42-32(46)20-34(3,4)5/h9-12,14-19H,6-8,13,20-21H2,1-5H3,(H,40,45)(H,42,46)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030717 (CHEMBL338342 | N-{4-Bromo-3-[4-(3-fluoro-2-(N-t-bu...) Show SMILES CCCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C36H35BrFN5O6S/c1-5-11-32-40-43(30-21-26(18-19-28(30)37)39-33(44)23-12-7-6-8-13-23)35(46)42(32)22-25-17-16-24(20-29(25)38)27-14-9-10-15-31(27)50(47,48)41-34(45)49-36(2,3)4/h6-10,12-21H,5,11,22H2,1-4H3,(H,39,44)(H,41,45)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030715 (CHEMBL338137 | N-{3-[3-Butyl-4-(3-fluoro-2-(N-t-bu...) Show SMILES CCCCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C38H37F4N5O6S/c1-5-6-16-33-44-47(31-22-27(19-20-29(31)38(40,41)42)43-34(48)24-12-8-7-9-13-24)36(50)46(33)23-26-18-17-25(21-30(26)39)28-14-10-11-15-32(28)54(51,52)45-35(49)53-37(2,3)4/h7-15,17-22H,5-6,16,23H2,1-4H3,(H,43,48)(H,45,49)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030702 (3-[3-Butyl-4-(3-fluoro-2'-(N-t-butyloxycarbonyl)-S...) Show SMILES CCCCc1nn(-c2cc(ccc2Cl)C(=O)NCCC)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H39ClFN5O6S/c1-6-8-13-30-38-41(28-20-23(16-17-26(28)35)31(42)37-18-7-2)33(44)40(30)21-24-15-14-22(19-27(24)36)25-11-9-10-12-29(25)48(45,46)39-32(43)47-34(3,4)5/h9-12,14-17,19-20H,6-8,13,18,21H2,1-5H3,(H,37,42)(H,39,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030711 (CHEMBL338027 | L-163958 | Pentanoic acid {4-bromo-...) Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C33H37BrFN5O6S/c1-6-8-13-30(41)36-23-16-17-25(34)27(19-23)40-32(43)39(29(7-2)37-40)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030692 (CHEMBL339672 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C35H32Cl2FN5O5S/c1-3-5-14-32-40-43(30-20-24(17-18-28(30)37)39-33(44)4-2)35(46)42(32)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)49(47,48)41-34(45)26-11-6-8-12-27(26)36/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,39,44)(H,41,45)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50282710 (CHEMBL34082 | N-Benzyl-N-{2-ethyl-4-oxo-3-[2'-(1H-...) Show SMILES CCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(Cc1ccccc1)C(=O)c1ccccc1 Show InChI InChI=1S/C38H31N7O2/c1-2-35-39-34-22-21-30(44(24-26-11-5-3-6-12-26)37(46)29-13-7-4-8-14-29)23-33(34)38(47)45(35)25-27-17-19-28(20-18-27)31-15-9-10-16-32(31)36-40-42-43-41-36/h3-23H,2,24-25H2,1H3,(H,40,41,42,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125 I]Sar1Ile8-AII from AT2 receptor of rat midbrain membrane				Bioorg Med Chem Lett 4: 1479-1484 (1994) Article DOI: 10.1016/S0960-894X(01)80517-5 BindingDB Entry DOI: 10.7270/Q2BC401G
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50032354 (CHEMBL433005 | isopentyloxy 2-[2-(4-{4-ethyl-5-[3-...) Show SMILES CCCc1nc(CC)c(C(=O)CCN(C(=O)c2cccnc2)c2cccnc2)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C41H45FN6O6S/c1-5-11-38-45-35(6-2)39(36(49)18-22-47(32-13-10-21-44-26-32)40(50)30-12-9-20-43-25-30)48(38)27-31-17-16-29(24-34(31)42)33-14-7-8-15-37(33)55(52,53)46-41(51)54-23-19-28(3)4/h7-10,12-17,20-21,24-26,28H,5-6,11,18-19,22-23,27H2,1-4H3,(H,46,51)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description Inhibition of [125I]-[Sar1,Ile8]Ang II binding at rat angiotensin II (type 2) receptor.				J Med Chem 38: 2938-45 (1995) BindingDB Entry DOI: 10.7270/Q2639NRN
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030709 (CHEMBL338434 | Pentanoic acid {3-[3-butyl-4-(3-flu...) Show SMILES CCCCC(=O)Nc1ccc(c(c1)-n1nc(CCCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O)C(F)(F)F Show InChI InChI=1S/C36H41F4N5O6S/c1-6-8-14-31-42-45(29-21-25(41-32(46)15-9-7-2)18-19-27(29)36(38,39)40)34(48)44(31)22-24-17-16-23(20-28(24)37)26-12-10-11-13-30(26)52(49,50)43-33(47)51-35(3,4)5/h10-13,16-21H,6-9,14-15,22H2,1-5H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50030700 (CHEMBL436396 | N-{4-Bromo-3-[4-(3-fluoro-2'-(N-t-b...) Show SMILES CCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C32H35BrFN5O6S/c1-6-10-28-36-39(26-18-22(15-16-24(26)33)35-29(40)7-2)31(42)38(28)19-21-14-13-20(17-25(21)34)23-11-8-9-12-27(23)46(43,44)37-30(41)45-32(3,4)5/h8-9,11-18H,6-7,10,19H2,1-5H3,(H,35,40)(H,37,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II type 2 receptor in rat adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair

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