Compile Data Set for Download or QSAR

Found 1531 hits of ic50 for UniProtKB: P08482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213281 (CHEMBL351561) Show SMILES C\C(=C\CO\N=C1/CN2CCC1C2)C#Cc1cccs1 |THB:5:6:12:10.9| Show InChI InChI=1S/C16H18N2OS/c1-13(4-5-15-3-2-10-20-15)7-9-19-17-16-12-18-8-6-14(16)11-18/h2-3,7,10,14H,6,8-9,11-12H2,1H3/b13-7-,17-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213074 (CHEMBL156050) Show SMILES C\C(=C\CO\N=C1/CN2CCC1C2)C#Cc1ccc(F)cc1 |THB:5:6:12:10.9| Show InChI InChI=1S/C18H19FN2O/c1-14(2-3-15-4-6-17(19)7-5-15)9-11-22-20-18-13-21-10-8-16(18)12-21/h4-7,9,16H,8,10-13H2,1H3/b14-9-,20-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213283 (CHEMBL350223) Show SMILES COc1ccc(cc1)C#C\C(C)=C/CO\N=C1/CN2CCC1C2 |THB:15:16:22:20.19| Show InChI InChI=1S/C19H22N2O2/c1-15(3-4-16-5-7-18(22-2)8-6-16)10-12-23-20-19-14-21-11-9-17(19)13-21/h5-8,10,17H,9,11-14H2,1-2H3/b15-10-,20-19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213207 (CHEMBL160582) Show SMILES C\C(=C\CO\N=C1/CN2CCC1C2)C#Cc1ccccc1 |THB:5:6:12:10.9| Show InChI InChI=1S/C18H20N2O/c1-15(7-8-16-5-3-2-4-6-16)10-12-21-19-18-14-20-11-9-17(18)13-20/h2-6,10,17H,9,11-14H2,1H3/b15-10-,19-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents		n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280622 (1-(3-Isothiocyanato-phenyl)-3-(4-{4-[2-oxo-2-(6-ox...) Show SMILES O=C(CN1CCN(CCCCCCCCCCNC(=S)Nc2cccc(c2)N=C=S)CC1)N1c2ccccc2C(=O)Nc2cccnc12 Show InChI InChI=1S/C36H44N8O2S2/c45-33(44-32-17-8-7-15-30(32)35(46)41-31-16-12-19-37-34(31)44)26-43-23-21-42(22-24-43)20-10-6-4-2-1-3-5-9-18-38-36(48)40-29-14-11-13-28(25-29)39-27-47/h7-8,11-17,19,25H,1-6,9-10,18,20-24,26H2,(H,41,46)(H2,38,40,48)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration of the compound was evaluated for irreversible inhibition at rat forebrain muscarinic receptor				Bioorg Med Chem Lett 2: 845-850 (1992) Article DOI: 10.1016/S0960-894X(00)80542-9 BindingDB Entry DOI: 10.7270/Q2F18ZMP
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50280565 (5-(1-Aza-bicyclo[2.2.1]hept-3-yl)-[1,2,4]oxadiazol...) Show SMILES Nc1noc(n1)C1CN2CCC1C2 |THB:4:6:12:10.9| Show InChI InChI=1S/C8H12N4O/c9-8-10-7(13-11-8)6-4-12-2-1-5(6)3-12/h5-6H,1-4H2,(H2,9,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of [3H]cis-methyldioxolane binding to label agonist sites (RCMD) in rat neocortex				Bioorg Med Chem Lett 2: 821-826 (1992) Article DOI: 10.1016/S0960-894X(00)80538-7 BindingDB Entry DOI: 10.7270/Q2PG1RNN
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062577 (6-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...) Show SMILES CCCSc1nsnc1OC1CN2CC1CCC2 |TLB:9:10:13:17.15.16| Show InChI InChI=1S/C12H19N3OS2/c1-2-6-17-12-11(13-18-14-12)16-10-8-15-5-3-4-9(10)7-15/h9-10H,2-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50033155 (3-(3-Butylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...) Show SMILES CCCCSc1nccnc1C1CN2CCC1CC2 |(4.41,-8.01,;5.75,-8.78,;5.74,-10.32,;7.07,-11.09,;7.07,-12.63,;8.4,-13.4,;9.74,-12.65,;11.07,-13.42,;11.07,-14.96,;9.73,-15.71,;8.41,-14.94,;7.07,-15.71,;7.07,-17.25,;5.74,-18.01,;6.28,-16.47,;5,-16.36,;5.74,-14.93,;4.42,-15.71,;4.42,-17.25,)| Show InChI InChI=1S/C15H23N3S/c1-2-3-10-19-15-14(16-6-7-17-15)13-11-18-8-4-12(13)5-9-18/h6-7,12-13H,2-5,8-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.				J Med Chem 38: 3469-81 (1995) BindingDB Entry DOI: 10.7270/Q2TB17JZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213070 (CHEMBL405426) Show SMILES C\C(=C\CO\N=C1\CN2CCC1C2)C#Cc1ccc(Cl)cc1 |THB:5:6:12:10.9| Show InChI InChI=1S/C18H19ClN2O/c1-14(2-3-15-4-6-17(19)7-5-15)9-11-22-20-18-13-21-10-8-16(18)12-21/h4-7,9,16H,8,10-13H2,1H3/b14-9-,20-18-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50033155 (3-(3-Butylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...) Show SMILES CCCCSc1nccnc1C1CN2CCC1CC2 |(4.41,-8.01,;5.75,-8.78,;5.74,-10.32,;7.07,-11.09,;7.07,-12.63,;8.4,-13.4,;9.74,-12.65,;11.07,-13.42,;11.07,-14.96,;9.73,-15.71,;8.41,-14.94,;7.07,-15.71,;7.07,-17.25,;5.74,-18.01,;6.28,-16.47,;5,-16.36,;5.74,-14.93,;4.42,-15.71,;4.42,-17.25,)| Show InChI InChI=1S/C15H23N3S/c1-2-3-10-19-15-14(16-6-7-17-15)13-11-18-8-4-12(13)5-9-18/h6-7,12-13H,2-5,8-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.				J Med Chem 38: 3469-81 (1995) BindingDB Entry DOI: 10.7270/Q2TB17JZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213278 (CHEMBL156445) Show SMILES COc1cccc(c1)C#C\C(C)=C/CO\N=C1/CN2CCC1C2 |THB:15:16:22:20.19| Show InChI InChI=1S/C19H22N2O2/c1-15(6-7-16-4-3-5-18(12-16)22-2)9-11-23-20-19-14-21-10-8-17(19)13-21/h3-5,9,12,17H,8,10-11,13-14H2,1-2H3/b15-9-,20-19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062577 (6-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...) Show SMILES CCCSc1nsnc1OC1CN2CC1CCC2 |TLB:9:10:13:17.15.16| Show InChI InChI=1S/C12H19N3OS2/c1-2-6-17-12-11(13-18-14-12)16-10-8-15-5-3-4-9(10)7-15/h9-10H,2-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062577 (6-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...) Show SMILES CCCSc1nsnc1OC1CN2CC1CCC2 |TLB:9:10:13:17.15.16| Show InChI InChI=1S/C12H19N3OS2/c1-2-6-17-12-11(13-18-14-12)16-10-8-15-5-3-4-9(10)7-15/h9-10H,2-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213077 (CHEMBL348412) Show SMILES C\C(=C\CO\N=C1/CN2CCC1C2)C#Cc1ccc(C)cc1 |THB:5:6:12:10.9| Show InChI InChI=1S/C19H22N2O/c1-15-3-6-17(7-4-15)8-5-16(2)10-12-22-20-19-14-21-11-9-18(19)13-21/h3-4,6-7,10,18H,9,11-14H2,1-2H3/b16-10-,20-19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062595 (3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-aza-...) Show SMILES CCCSc1nsnc1C1CN2CCC1C2 |THB:8:9:15:13.12| Show InChI InChI=1S/C11H17N3S2/c1-2-5-15-11-10(12-16-13-11)9-7-14-4-3-8(9)6-14/h8-9H,2-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062595 (3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-aza-...) Show SMILES CCCSc1nsnc1C1CN2CCC1C2 |THB:8:9:15:13.12| Show InChI InChI=1S/C11H17N3S2/c1-2-5-15-11-10(12-16-13-11)9-7-14-4-3-8(9)6-14/h8-9H,2-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50033162 (3-(3-Pentylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2....) Show SMILES CCCCCSc1nccnc1C1CN2CCC1CC2 |(5.44,2.49,;5.44,.95,;6.77,.18,;6.77,-1.36,;8.1,-2.13,;8.1,-3.67,;9.43,-4.44,;10.76,-3.69,;12.09,-4.46,;12.09,-6,;10.76,-6.75,;9.43,-5.98,;8.1,-6.75,;8.1,-8.29,;6.77,-9.05,;7.31,-7.51,;6.03,-7.4,;6.77,-5.97,;5.44,-6.75,;5.44,-8.29,)| Show InChI InChI=1S/C16H25N3S/c1-2-3-4-11-20-16-15(17-7-8-18-16)14-12-19-9-5-13(14)6-10-19/h7-8,13-14H,2-6,9-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.				J Med Chem 38: 3469-81 (1995) BindingDB Entry DOI: 10.7270/Q2TB17JZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50070692 (CHEMBL99240) Show SMILES [H][C@@]12CC[N@@](C[C@@H]1c1nsnc1OCCCCCC)C2 Show InChI InChI=1S/C34H50N8O8/c1-3-20(2)28(42-30(46)24(12-7-8-16-35)39-29(45)23-19-22(43)14-15-27(23)44)32(48)41-26(18-21-10-5-4-6-11-21)31(47)40-25(33(49)50)13-9-17-38-34(36)37/h4-6,10-11,14-15,19-20,24-26,28,43-44H,3,7-9,12-13,16-18,35H2,1-2H3,(H,39,45)(H,40,47)(H,41,48)(H,42,46)(H,49,50)(H4,36,37,38)/t20?,24-,25-,26-,28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062570 (3-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...) Show SMILES CCCSc1nsnc1OC1CN2CCC1C2 |THB:9:10:16:14.13| Show InChI InChI=1S/C11H17N3OS2/c1-2-5-16-11-10(12-17-13-11)15-9-7-14-4-3-8(9)6-14/h8-9H,2-7H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50291551 (CHEMBL274329 | Trimethyl-[4-(3-oxo-isoxazolidin-2-...) Show SMILES C[N+](C)(C)CC#CCN1OCCC1=O Show InChI InChI=1S/C10H17N2O2/c1-12(2,3)8-5-4-7-11-10(13)6-9-14-11/h6-9H2,1-3H3/q+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Muscarinic receptor M2 in rat heart using [3H]-QNB (quinuclidinyl benzylate) radioligand as a M2 non-selective muscarinic receptor antagonist at a co...				Bioorg Med Chem Lett 7: 1033-1036 (1997) Article DOI: 10.1016/S0960-894X(97)00150-9 BindingDB Entry DOI: 10.7270/Q2S46RZ2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50072214 ((R)-3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiaz...) Show SMILES C(Oc1nsnc1[C@H]1CN2CCC1C2)C#Cc1ccccc1 Show InChI InChI=1S/C17H17N3OS/c1-2-5-13(6-3-1)7-4-10-21-17-16(18-22-19-17)15-12-20-9-8-14(15)11-20/h1-3,5-6,14-15H,8-12H2/t14?,15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213286 (CHEMBL346580) Show SMILES C\C(=C/CO\N=C1/CN2CCC1C2)C#Cc1ccc(Cl)c(Cl)c1 |THB:5:6:12:10.9| Show InChI InChI=1S/C18H18Cl2N2O/c1-13(2-3-14-4-5-16(19)17(20)10-14)7-9-23-21-18-12-22-8-6-15(18)11-22/h4-5,7,10,15H,6,8-9,11-12H2,1H3/b13-7+,21-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006582 (1-Methyl-5-(4-propylsulfanyl-[1,2,5]thiadiazol-3-y...) Show SMILES CCCSc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3S2/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk CNS Division Curated by ChEMBL					Assay Description In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligand				J Med Chem 35: 2274-83 (1992) BindingDB Entry DOI: 10.7270/Q22J69TH
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Clc1ccc(cn1)C1CC2CCC1N2 |TLB:4:7:11.10:13| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description In vitro displacement of [3H]oxotremorine-M from muscarinic acetylcholine receptor in rat brain cortex				J Med Chem 42: 4970-80 (1999) Article DOI: 10.1021/jm9910627 BindingDB Entry DOI: 10.7270/Q2K0770F
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50065207 (1-Aza-bicyclo[2.2.1]heptan-3-one O-((Z)-3-methyl-p...) Show SMILES C\C(=C\CO\N=C1/CN2CCC1C2)C#C Show InChI InChI=1S/C12H16N2O/c1-3-10(2)5-7-15-13-12-9-14-6-4-11(12)8-14/h1,5,11H,4,6-9H2,2H3/b10-5-,13-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213279 (CHEMBL345415) Show SMILES C\C(=C\CO\N=C1\CN2CCC1C2)C#Cc1ccccc1 |THB:5:6:12:10.9| Show InChI InChI=1S/C18H20N2O/c1-15(7-8-16-5-3-2-4-6-16)10-12-21-19-18-14-20-11-9-17(18)13-20/h2-6,10,17H,9,11-14H2,1H3/b15-10-,19-18-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50033162 (3-(3-Pentylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2....) Show SMILES CCCCCSc1nccnc1C1CN2CCC1CC2 |(5.44,2.49,;5.44,.95,;6.77,.18,;6.77,-1.36,;8.1,-2.13,;8.1,-3.67,;9.43,-4.44,;10.76,-3.69,;12.09,-4.46,;12.09,-6,;10.76,-6.75,;9.43,-5.98,;8.1,-6.75,;8.1,-8.29,;6.77,-9.05,;7.31,-7.51,;6.03,-7.4,;6.77,-5.97,;5.44,-6.75,;5.44,-8.29,)| Show InChI InChI=1S/C16H25N3S/c1-2-3-4-11-20-16-15(17-7-8-18-16)14-12-19-9-5-13(14)6-10-19/h7-8,13-14H,2-6,9-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.				J Med Chem 38: 3469-81 (1995) BindingDB Entry DOI: 10.7270/Q2TB17JZ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50070735 (CHEMBL317324) Show SMILES [H][C@]12C[N@](C[C@@H]1c1nsnc1OCCCCCC)CCC2 Show InChI InChI=1S/C29H48N8O8/c1-4-16(3)23(27(43)34-19(5-2)28(44)45)37-26(42)21(10-8-14-33-29(31)32)36-25(41)20(9-6-7-13-30)35-24(40)18-15-17(38)11-12-22(18)39/h11-12,15-16,19-21,23,38-39H,4-10,13-14,30H2,1-3H3,(H,34,43)(H,35,40)(H,36,41)(H,37,42)(H,44,45)(H4,31,32,33)/t16?,19?,20-,21-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50072227 ((1R,5R,6R)-6-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]t...) Show SMILES C(Oc1nsnc1[C@H]1C[N@]2C[C@@H]1CCC2)C#Cc1ccccc1 Show InChI InChI=1S/C18H19N3OS/c1-2-6-14(7-3-1)8-5-11-22-18-17(19-23-20-18)16-13-21-10-4-9-15(16)12-21/h1-3,6-7,15-16H,4,9-13H2/t15-,16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50070647 (CHEMBL329924) Show SMILES [H][C@]12C[N@](C[C@@H]1c1nsnc1SCCCc1ccccc1)CCC2 Show InChI InChI=1S/C18H23N5O/c1-3-6-13-7-4-5-8-14(13)9-15(12(2)24)23-11-22-16-17(19)20-10-21-18(16)23/h4-5,7-8,10-12,15,24H,3,6,9H2,1-2H3,(H2,19,20,21)/t12-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006572 (5-(4-Butylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-methy...) Show SMILES CCCCSc1nsnc1C1=CCCN(C)C1 |t:11| Show InChI InChI=1S/C12H19N3S2/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk CNS Division Curated by ChEMBL					Assay Description In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligand				J Med Chem 35: 2274-83 (1992) BindingDB Entry DOI: 10.7270/Q22J69TH
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006572 (5-(4-Butylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-methy...) Show SMILES CCCCSc1nsnc1C1=CCCN(C)C1 |t:11| Show InChI InChI=1S/C12H19N3S2/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk CNS Division Curated by ChEMBL					Assay Description In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligand				J Med Chem 35: 2274-83 (1992) BindingDB Entry DOI: 10.7270/Q22J69TH
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50070725 (CHEMBL318403) Show SMILES CN1CCC=C(C1)c1nsnc1SCCCc1ccccc1 |c:4| Show InChI InChI=1S/C28H43N5O8/c1-4-16(3)23(26(38)30-19(5-2)28(40)41)32-25(37)21-10-8-14-33(21)27(39)20(9-6-7-13-29)31-24(36)18-15-17(34)11-12-22(18)35/h11-12,15-16,19-21,23,34-35H,4-10,13-14,29H2,1-3H3,(H,30,38)(H,31,36)(H,32,37)(H,40,41)/t16?,19?,20-,21-,23-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50367705 (SULFOARECOLINE IODIDE) Show SMILES COC(=O)C1=CCC[S+](C)C1 |t:4| Show InChI InChI=1S/C8H13O2S/c1-10-8(9)7-4-3-5-11(2)6-7/h4H,3,5-6H2,1-2H3/q+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of [3H]oxotremorine-M binding to rat brain membrane Muscarinic acetylcholine receptor				J Med Chem 31: 1312-6 (1988) BindingDB Entry DOI: 10.7270/Q2B27VW2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50003351 (3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...) Show SMILES CCCCOc1nsnc1C1=CCCN(C)C1 |t:11| Show InChI InChI=1S/C12H19N3OS/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranes				Bioorg Med Chem Lett 2: 809-814 (1992) Article DOI: 10.1016/S0960-894X(00)80536-3 BindingDB Entry DOI: 10.7270/Q2T72HBX
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003351 (3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...) Show SMILES CCCCOc1nsnc1C1=CCCN(C)C1 |t:11| Show InChI InChI=1S/C12H19N3OS/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-oxotremorine-M (Oxo-M) from rat hippocampus muscarinic acetylcholine receptor M1				J Med Chem 35: 4011-9 (1992) BindingDB Entry DOI: 10.7270/Q2KW5F1K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003351 (3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...) Show SMILES CCCCOc1nsnc1C1=CCCN(C)C1 |t:11| Show InChI InChI=1S/C12H19N3OS/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk CNS Division Curated by ChEMBL					Assay Description In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligand				J Med Chem 35: 2274-83 (1992) BindingDB Entry DOI: 10.7270/Q22J69TH
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213079 (CHEMBL160928) Show SMILES COc1ccc(cc1OC)C#C\C(C)=C/CO\N=C1/CN2CCC1C2 |THB:17:18:24:22.21| Show InChI InChI=1S/C20H24N2O3/c1-15(4-5-16-6-7-19(23-2)20(12-16)24-3)9-11-25-21-18-14-22-10-8-17(18)13-22/h6-7,9,12,17H,8,10-11,13-14H2,1-3H3/b15-9-,21-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50003351 (3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...) Show SMILES CCCCOc1nsnc1C1=CCCN(C)C1 |t:11| Show InChI InChI=1S/C12H19N3OS/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003351 (3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...) Show SMILES CCCCOc1nsnc1C1=CCCN(C)C1 |t:11| Show InChI InChI=1S/C12H19N3OS/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk CNS Division Curated by ChEMBL					Assay Description In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-oxotremorine-M (Oxo-M) as radioligand				J Med Chem 35: 2274-83 (1992) BindingDB Entry DOI: 10.7270/Q22J69TH
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50004665 ((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...) Show SMILES O=C1CCCN1CC#CCN1CCCC1 Show InChI InChI=1S/C12H18N2O/c15-12-6-5-11-14(12)10-4-3-9-13-7-1-2-8-13/h1-2,5-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 0.1 nM [3H]cis-methyldioxolane binding to rat neocortex muscarinic receptor				Bioorg Med Chem Lett 2: 803-808 (1992) Article DOI: 10.1016/S0960-894X(00)80535-1 BindingDB Entry DOI: 10.7270/Q2Z0382N
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against rat hippocampus Muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) as radioligand				J Med Chem 35: 4011-9 (1992) BindingDB Entry DOI: 10.7270/Q2KW5F1K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50223182 (2-(4-(pyrrolidin-1-yl)but-2-ynyl)isoxazolidin-3-on...) Show SMILES O=C1CCON1CC#CCN1CCCC1 Show InChI InChI=1S/C11H16N2O2/c14-11-5-10-15-13(11)9-4-3-8-12-6-1-2-7-12/h1-2,5-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Muscarinic receptor M2 in rat brain using [3H]-QNB (quinuclidinyl benzylate) radioligand at a concentration of 0.12 nM				Bioorg Med Chem Lett 7: 1033-1036 (1997) Article DOI: 10.1016/S0960-894X(97)00150-9 BindingDB Entry DOI: 10.7270/Q2S46RZ2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50213071 (CHEMBL160939) Show SMILES C\C(=C\CO\N=C1\CN2CCC1C2)C#Cc1ccc(F)cc1 |THB:5:6:12:10.9| Show InChI InChI=1S/C18H19FN2O/c1-14(2-3-15-4-6-17(19)7-5-15)9-11-22-20-18-13-21-10-8-16(18)12-21/h4-7,9,16H,8,10-13H2,1H3/b14-9-,20-18-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against muscarinic receptor using radioligand [3H]cis-methyldioxolane (CMD) binding assay in membrane preparations of rat neocortex.				Citation and Details BindingDB Entry DOI: 10.7270/Q23B628P
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50003369 (1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...) Show SMILES CCCOc1nsnc1C1=CCCN(C)C1 |t:10| Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk CNS Division Curated by ChEMBL					Assay Description In vitro binding affinity against muscarinic acetylcholine receptor M1 from rat hippocampus, using [3H]-pirenzepine (Pz) as radioligand				J Med Chem 35: 2274-83 (1992) BindingDB Entry DOI: 10.7270/Q22J69TH
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50072225 ((1R,5R,6R)-6-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,...) Show SMILES C(Sc1nsnc1[C@H]1C[N@]2C[C@@H]1CCC2)C#Cc1ccccc1 Show InChI InChI=1S/C18H19N3S2/c1-2-6-14(7-3-1)8-5-11-22-18-17(19-23-20-18)16-13-21-10-4-9-15(16)12-21/h1-3,6-7,15-16H,4,9-13H2/t15-,16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50070684 (CHEMBL321073) Show SMILES [H][C@@]12CC[N@@](C[C@@H]1c1nsnc1SCCCc1ccccc1)C2 Show InChI InChI=1S/C28H43N7O8/c1-4-15(3)22(25(40)32-18(5-2)27(42)43)34-24(39)20-9-7-13-35(20)26(41)19(8-6-12-31-28(29)30)33-23(38)17-14-16(36)10-11-21(17)37/h10-11,14-15,18-20,22,36-37H,4-9,12-13H2,1-3H3,(H,32,40)(H,33,38)(H,34,39)(H,42,43)(H4,29,30,31)/t15?,18?,19-,20-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM46858 (1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid...) Show SMILES COC(=O)C1=CCCN(C)C1 |t:4| Show InChI InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of [3H]oxotremorine-M binding to rat brain membrane Muscarinic acetylcholine receptor				J Med Chem 31: 1312-6 (1988) BindingDB Entry DOI: 10.7270/Q2B27VW2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50003366 (1-Methyl-5-(4-pentyloxy-[1,2,5]thiadiazol-3-yl)-1,...) Show SMILES CCCCCOc1nsnc1C1=CCCN(C)C1 |t:12| Show InChI InChI=1S/C13H21N3OS/c1-3-4-5-9-17-13-12(14-18-15-13)11-7-6-8-16(2)10-11/h7H,3-6,8-10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
					More data for this Ligand-Target Pair

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