Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nociceptin receptor (RAT) | BDBM50087691 (8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.0790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087692 (8-Cyclodecyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.0820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087687 (8-Cyclononyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM21842 ((2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by PDSP Ki Database | J Chem Neuroanat 25: 233-47 (2003) Article DOI: 10.1016/s0891-0618(03)00032-2 BindingDB Entry DOI: 10.7270/Q2XP73G2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087698 (8-(R)-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087697 (8-Cycloundecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087685 (8-Cyclododecyl-1-phenyl-1,3,8-triaza-spiro[4.5]dec...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087690 (8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087684 (8-Cyclooctyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087693 (1-Phenyl-8-(4-propyl-cyclohexyl)-1,3,8-triaza-spir...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM86660 (OFQ/N UFP-102) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Section of Pharmacology Curated by PDSP Ki Database | J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087683 (8-(4-tert-Butyl-cyclohexyl)-1-phenyl-1,3,8-triaza-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087689 (8-(4-Isopropyl-cyclohexyl)-1-phenyl-1,3,8-triaza-s...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087686 (8-Cycloheptyl-1-phenyl-1,3,8-triaza-spiro[4.5]deca...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087694 (8-(4-Methyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spir...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167767 (((2S,3aS,12bS)-11-Fluoro-2,3,3a,12b-tetrahydro-1,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087701 (8-(4-tert-Butyl-cyclohexyl)-1-phenyl-1,3,8-triaza-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167760 (((2S,3aS,12bS)-11-Chloro-2,3,3a,12b-tetrahydro-1,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087695 (8-Cyclohexyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167755 (((2R,3aS,12bS)-11-Chloro-2,3,3a,12b-tetrahydro-1,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167763 (((2R,3aS,12bS)-11-Fluoro-2,3,3a,12b-tetrahydro-1,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087699 (8-(4-Methyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spir...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087688 (1-Phenyl-8-(4-propyl-cyclohexyl)-1,3,8-triaza-spir...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167768 (((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM85822 (Demethyl-AMPA | OFQ/N | OFQ/N (1-11) | OFQ/N (1-11...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 57.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Section of Pharmacology Curated by PDSP Ki Database | J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167754 (CHEMBL194994 | Dimethyl-[(2R,3aS,12bR)-1-(2,3,3a,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167762 (((2S,3aS,12bS)-11-Methoxy-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50146344 (CHEMBL330713 | Dimethyl-[(3aS,12bS)-1-(2,3,3a,12b-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 88 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167753 (8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167759 (((2R,3aS,12bS)-11-Methoxy-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167766 (((2R,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167756 (8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 142 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087700 (8-Bicyclohexyl-4-yl-1-phenyl-1,3,8-triaza-spiro[4....) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50087696 (8-Cyclopentadecyl-1-phenyl-1,3,8-triaza-spiro[4.5]...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human embryonic kidney 293 cells overexpressing rat Opioid receptor like 1 | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167769 (8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167761 (CHEMBL427007 | [8-((2S,3aS,12bS)-11-Bromo-2,3,3a,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167758 (1-[8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167771 (8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167770 (8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167764 (8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM50167765 (8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL | Assay Description In vitro binding affinity against norepinephrin transpoter using [3H]-nisoxetine as radioligand | Bioorg Med Chem Lett 15: 2898-901 (2005) Article DOI: 10.1016/j.bmcl.2005.03.076 BindingDB Entry DOI: 10.7270/Q29C6X0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM86252 (CAS_0 | NSC_0 | OFQ II 1-28) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by PDSP Ki Database | J Chem Neuroanat 25: 233-47 (2003) Article DOI: 10.1016/s0891-0618(03)00032-2 BindingDB Entry DOI: 10.7270/Q2XP73G2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (RAT) | BDBM86254 (OFQ II 1-17) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by PDSP Ki Database | J Chem Neuroanat 25: 233-47 (2003) Article DOI: 10.1016/s0891-0618(03)00032-2 BindingDB Entry DOI: 10.7270/Q2XP73G2 | ||||||||||||
More data for this Ligand-Target Pair |