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Compile Data Set for Download or QSAR

Found 12 hits of ic50 data for polymerid = 50006731   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50063698
PNG
(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Show SMILES NC(N)=Nc1ccc(cc1)C(=O)Oc1ccc2cc(ccc2c1)C(N)=N
Show InChI InChI=1S/C19H17N5O2/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23/h1-10H,(H3,20,21)(H4,22,23,24)
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n/an/a 150n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069128
PNG
(CHEMBL3403524)
Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(cc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C14H11ClN4O4/c15-11-7-10(19(21)22)5-6-12(11)23-13(20)8-1-3-9(4-2-8)18-14(16)17/h1-7H,(H4,16,17,18)
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n/an/a 300n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069127
PNG
(CHEMBL3403525)
Show SMILES COC(=O)c1ccc2cc(OC(=O)c3ccc(NC(N)=N)cc3)ccc2c1
Show InChI InChI=1S/C20H17N3O4/c1-26-18(24)15-3-2-14-11-17(9-6-13(14)10-15)27-19(25)12-4-7-16(8-5-12)23-20(21)22/h2-11H,1H3,(H4,21,22,23)
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n/an/a 600n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069132
PNG
(CHEMBL550687)
Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C14H12N4O4/c15-14(16)17-10-3-1-9(2-4-10)13(19)22-12-7-5-11(6-8-12)18(20)21/h1-8H,(H4,15,16,17)
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n/an/a 820n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069133
PNG
(CHEMBL1195245)
Show SMILES COC(=O)c1ccc(OC(=O)c2ccc(NC(N)=N)cc2)cc1
Show InChI InChI=1S/C16H15N3O4/c1-22-14(20)10-4-8-13(9-5-10)23-15(21)11-2-6-12(7-3-11)19-16(17)18/h2-9H,1H3,(H4,17,18,19)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069129
PNG
(CHEMBL3403523)
Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Oc1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C14H12N4O4/c15-14(16)17-10-6-4-9(5-7-10)13(19)22-12-3-1-2-11(8-12)18(20)21/h1-8H,(H4,15,16,17)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069131
PNG
(CHEMBL3403522)
Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(cc1)C(N)=O
Show InChI InChI=1S/C15H14N4O3/c16-13(20)9-3-7-12(8-4-9)22-14(21)10-1-5-11(6-2-10)19-15(17)18/h1-8H,(H2,16,20)(H4,17,18,19)
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n/an/a 6.80E+3n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50424712
PNG
(CAMOSTAT | Camostat Mesilate | Foipan)
Show SMILES CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(cc2)N=C(N)N)cc1
Show InChI InChI=1S/C20H22N4O5/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22/h3-10H,11-12H2,1-2H3,(H4,21,22,23)
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n/an/a 3.20E+4n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069124
PNG
(CHEMBL535214)
Show SMILES NC(=N)Nc1ccc(cc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C14H14N4O/c15-14(16)18-12-8-6-10(7-9-12)13(19)17-11-4-2-1-3-5-11/h1-9H,(H,17,19)(H4,15,16,18)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069126
PNG
(CHEMBL3403526)
Show SMILES COC(=O)c1ccc2cc(NS(=O)(=O)c3ccc(NC(N)=N)cc3)ccc2c1
Show InChI InChI=1S/C19H18N4O4S/c1-27-18(24)14-3-2-13-11-16(5-4-12(13)10-14)23-28(25,26)17-8-6-15(7-9-17)22-19(20)21/h2-11,23H,1H3,(H4,20,21,22)
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Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069125
PNG
(CHEMBL3403527)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(NC(N)=N)cc1
Show InChI InChI=1S/C14H16N4O2S/c1-10-2-8-13(9-3-10)21(19,20)18-12-6-4-11(5-7-12)17-14(15)16/h2-9,18H,1H3,(H4,15,16,17)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair
Hepatocyte growth factor activator


(Homo sapiens (Human))
BDBM50069123
PNG
(CHEMBL579653)
Show SMILES NC(=N)Nc1ccc(NC(=O)c2ccccc2)cc1
Show InChI InChI=1S/C14H14N4O/c15-14(16)18-12-8-6-11(7-9-12)17-13(19)10-4-2-1-3-5-10/h1-9H,(H,17,19)(H4,15,16,18)
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n/an/a>5.00E+4n/an/an/an/an/an/a



Washington University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...


Bioorg Med Chem 23: 2328-43 (2015)

More data for this
Ligand-Target Pair