Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Homoserine kinase (Escherichia coli) | BDBM85124 (Thr1 inhibitor, 4) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 460 | -8.99 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
McMaster University | Assay Description The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o... | Chembiochem 12: 1179-82 (2011) Article DOI: 10.1002/cbic.201100121 BindingDB Entry DOI: 10.7270/Q24T6GWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoserine kinase (Escherichia coli) | BDBM85126 (Thr1 inhibitor, 6) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.60E+3 | -7.18 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
McMaster University | Assay Description The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o... | Chembiochem 12: 1179-82 (2011) Article DOI: 10.1002/cbic.201100121 BindingDB Entry DOI: 10.7270/Q24T6GWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoserine kinase (Escherichia coli) | BDBM24941 ((2Z)-2-{[(2,5-dibromophenyl)amino](hydroxy)methyli...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.20E+4 | -6.98 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
McMaster University | Assay Description The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o... | Chembiochem 12: 1179-82 (2011) Article DOI: 10.1002/cbic.201100121 BindingDB Entry DOI: 10.7270/Q24T6GWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoserine kinase (Escherichia coli) | BDBM85123 (Thr1 inhibitor, 3 | cid_235240) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.71E+4 | -6.48 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
McMaster University | Assay Description The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o... | Chembiochem 12: 1179-82 (2011) Article DOI: 10.1002/cbic.201100121 BindingDB Entry DOI: 10.7270/Q24T6GWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoserine kinase (Escherichia coli) | BDBM85122 (Thr1 inhibitor, 1) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents | Article PubMed | 3.20E+4 | -6.37 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
McMaster University | Assay Description The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o... | Chembiochem 12: 1179-82 (2011) Article DOI: 10.1002/cbic.201100121 BindingDB Entry DOI: 10.7270/Q24T6GWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoserine kinase (Escherichia coli) | BDBM85125 (Thr1 inhibitor, 5) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 3.58E+4 | -6.31 | n/a | n/a | n/a | n/a | n/a | 7.5 | 37 |
McMaster University | Assay Description The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o... | Chembiochem 12: 1179-82 (2011) Article DOI: 10.1002/cbic.201100121 BindingDB Entry DOI: 10.7270/Q24T6GWV | |||||||||||
More data for this Ligand-Target Pair |