Compile Data Set for Download or QSAR

Found 32 hits of ic50 data for polymerid = 6170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144342 (3-((1R,3S)-3-Amino-cyclopentyl)-2-[1-(3,3-dimethyl...) Show SMILES CC(C)(C)CCn1cnc(c1)C(C[C@H]1CC[C@H](N)C1)C(O)=O Show InChI InChI=1S/C17H29N3O2/c1-17(2,3)6-7-20-10-15(19-11-20)14(16(21)22)9-12-4-5-13(18)8-12/h10-14H,4-9,18H2,1-3H3,(H,21,22)/t12-,13-,14?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50089691 (CHEMBL3577425) Show SMILES CC1(C)C2CCC1(C)CC2NC(=O)[C@@H](CC1CCCCC1)NC(=O)N[C@@H](CCCCN)C(O)=O |r,TLB:10:9:5.4:1| Show InChI InChI=1S/C26H46N4O4/c1-25(2)18-12-13-26(25,3)16-21(18)28-22(31)20(15-17-9-5-4-6-10-17)30-24(34)29-19(23(32)33)11-7-8-14-27/h17-21H,4-16,27H2,1-3H3,(H,28,31)(H,32,33)(H2,29,30,34)/t18?,19-,20+,21?,26?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Infection Research Curated by ChEMBL					Assay Description Inhibition of CBP (unknown origin)				J Med Chem 58: 4839-44 (2015) Article DOI: 10.1021/jm501840b BindingDB Entry DOI: 10.7270/Q24B3314
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144336 (3-(6-Amino-5-methyl-pyridin-3-yl)-2-[1-(3-methyl-b...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1cnc(N)c(C)c1)C(O)=O Show InChI InChI=1S/C17H24N4O2/c1-11(2)4-5-21-9-15(20-10-21)14(17(22)23)7-13-6-12(3)16(18)19-8-13/h6,8-11,14H,4-5,7H2,1-3H3,(H2,18,19)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144333 (3-(6-Amino-5-methyl-pyridin-3-yl)-2-[1-(4-methyl-p...) Show SMILES CC(C)CCCn1cnc(c1)C(Cc1cnc(N)c(C)c1)C(O)=O Show InChI InChI=1S/C18H26N4O2/c1-12(2)5-4-6-22-10-16(21-11-22)15(18(23)24)8-14-7-13(3)17(19)20-9-14/h7,9-12,15H,4-6,8H2,1-3H3,(H2,19,20)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120796 (US8710232, 33) Show SMILES CC1(C)CCC(CC1)n1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C19H26N4O2/c1-19(2)7-5-14(6-8-19)23-11-16(22-12-23)15(18(24)25)9-13-3-4-17(20)21-10-13/h3-4,10-12,14-15H,5-9H2,1-2H3,(H2,20,21)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50135934 (3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...) Show SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C16H22N4O2/c1-11(2)5-6-20-9-14(19-10-20)13(16(21)22)7-12-3-4-15(17)18-8-12/h3-4,8-11,13H,5-7H2,1-2H3,(H2,17,18)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144337 (3-(6-Amino-pyridin-3-yl)-2-[1-(4-methyl-pentyl)-1H...) Show SMILES CC(C)CCCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C17H24N4O2/c1-12(2)4-3-7-21-10-15(20-11-21)14(17(22)23)8-13-5-6-16(18)19-9-13/h5-6,9-12,14H,3-4,7-8H2,1-2H3,(H2,18,19)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120790 (US8710232, 17) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(CC3CCCN(C3)C(=O)C(c3ccccc3)c3ccccc3)cn2)cn1 Show InChI InChI=1S/C31H33N5O3/c32-28-14-13-22(17-33-28)16-26(31(38)39)27-20-35(21-34-27)18-23-8-7-15-36(19-23)30(37)29(24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-6,9-14,17,20-21,23,26,29H,7-8,15-16,18-19H2,(H2,32,33)(H,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120788 (US8710232, 15) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(CC3CCCCN3C(=O)c3ccccc3)cn2)cn1 Show InChI InChI=1S/C24H27N5O3/c25-22-10-9-17(13-26-22)12-20(24(31)32)21-15-28(16-27-21)14-19-8-4-5-11-29(19)23(30)18-6-2-1-3-7-18/h1-3,6-7,9-10,13,15-16,19-20H,4-5,8,11-12,14H2,(H2,25,26)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120787 (US8710232, 13) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(CCC3CCN(CC3)C(=O)C(c3ccccc3)c3ccccc3)cn2)cn1 Show InChI InChI=1S/C32H35N5O3/c33-29-12-11-24(20-34-29)19-27(32(39)40)28-21-36(22-35-28)16-13-23-14-17-37(18-15-23)31(38)30(25-7-3-1-4-8-25)26-9-5-2-6-10-26/h1-12,20-23,27,30H,13-19H2,(H2,33,34)(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120786 (US8710232, 12) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(cn2)-c2ccc(NC(=O)Nc3ccccc3)cc2)cn1 Show InChI InChI=1S/C24H22N6O3/c25-22-11-6-16(13-26-22)12-20(23(31)32)21-14-30(15-27-21)19-9-7-18(8-10-19)29-24(33)28-17-4-2-1-3-5-17/h1-11,13-15,20H,12H2,(H2,25,26)(H,31,32)(H2,28,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120782 (US8710232, 7) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(cn2)C2CCCC2)cn1 Show InChI InChI=1S/C16H20N4O2/c17-15-6-5-11(8-18-15)7-13(16(21)22)14-9-20(10-19-14)12-3-1-2-4-12/h5-6,8-10,12-13H,1-4,7H2,(H2,17,18)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144316 (3-(6-Amino-5-methyl-pyridin-3-yl)-2-(1H-imidazol-4...) Show SMILES Cc1cc(CC(C(O)=O)c2cnc[nH]2)cnc1N Show InChI InChI=1S/C12H14N4O2/c1-7-2-8(4-15-11(7)13)3-9(12(17)18)10-5-14-6-16-10/h2,4-6,9H,3H2,1H3,(H2,13,15)(H,14,16)(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120791 (US8710232, 18) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(CCC3CCN(CC3)C(=O)CCc3ccccc3)cn2)cn1 Show InChI InChI=1S/C27H33N5O3/c28-25-8-6-22(17-29-25)16-23(27(34)35)24-18-31(19-30-24)13-10-21-11-14-32(15-12-21)26(33)9-7-20-4-2-1-3-5-20/h1-6,8,17-19,21,23H,7,9-16H2,(H2,28,29)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120785 (US8710232, 10) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(CC(=O)NC(c3ccccc3)c3ccccc3)cn2)cn1 Show InChI InChI=1S/C26H25N5O3/c27-23-12-11-18(14-28-23)13-21(26(33)34)22-15-31(17-29-22)16-24(32)30-25(19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-12,14-15,17,21,25H,13,16H2,(H2,27,28)(H,30,32)(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120781 (US8710232, 1) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(cn2)C2CCCCC2)cn1 Show InChI InChI=1S/C17H22N4O2/c18-16-7-6-12(9-19-16)8-14(17(22)23)15-10-21(11-20-15)13-4-2-1-3-5-13/h6-7,9-11,13-14H,1-5,8H2,(H2,18,19)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120789 (US8710232, 16) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(CCC3CCCN(C3)C(=O)CCc3ccccc3)cn2)cn1 Show InChI InChI=1S/C27H33N5O3/c28-25-10-8-22(16-29-25)15-23(27(34)35)24-18-31(19-30-24)14-12-21-7-4-13-32(17-21)26(33)11-9-20-5-2-1-3-6-20/h1-3,5-6,8,10,16,18-19,21,23H,4,7,9,11-15,17H2,(H2,28,29)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120797 (US8710232, 37) Show SMILES CCCNC(=O)Nc1ccc(cc1)-n1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O Show InChI InChI=1S/C21H24N6O3/c1-2-9-23-21(30)26-15-4-6-16(7-5-15)27-12-18(25-13-27)17(20(28)29)10-14-3-8-19(22)24-11-14/h3-8,11-13,17H,2,9-10H2,1H3,(H2,22,24)(H,28,29)(H2,23,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50135933 (3-(6-Amino-pyridin-3-yl)-2-(1H-imidazol-4-yl)-prop...) Show SMILES Nc1ccc(CC(C(O)=O)c2cnc[nH]2)cn1 Show InChI InChI=1S/C11H12N4O2/c12-10-2-1-7(4-14-10)3-8(11(16)17)9-5-13-6-15-9/h1-2,4-6,8H,3H2,(H2,12,14)(H,13,15)(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144325 (3-((1R,3S)-3-Amino-cyclopentyl)-2-(1-ethyl-1H-imid...) Show SMILES CCn1cnc(c1)C(C[C@H]1CC[C@H](N)C1)C(O)=O Show InChI InChI=1S/C13H21N3O2/c1-2-16-7-12(15-8-16)11(13(17)18)6-9-3-4-10(14)5-9/h7-11H,2-6,14H2,1H3,(H,17,18)/t9-,10-,11?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144317 (6-Amino-2-[1-(3-methyl-butyl)-1H-imidazol-4-yl]-he...) Show SMILES CC(C)CCn1cnc(c1)C(CCCCN)C(O)=O Show InChI InChI=1S/C14H25N3O2/c1-11(2)6-8-17-9-13(16-10-17)12(14(18)19)5-3-4-7-15/h9-12H,3-8,15H2,1-2H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50089685 (CHEMBL3577333) Show SMILES CC(C)CCNC(=O)[C@@H](CCCCNC(=O)OCc1ccccc1)NC(=O)N[C@@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C26H43N5O6/c1-19(2)14-17-28-23(32)21(30-25(35)31-22(24(33)34)13-6-8-15-27)12-7-9-16-29-26(36)37-18-20-10-4-3-5-11-20/h3-5,10-11,19,21-22H,6-9,12-18,27H2,1-2H3,(H,28,32)(H,29,36)(H,33,34)(H2,30,31,35)/t21-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Infection Research Curated by ChEMBL					Assay Description Inhibition of CBP (unknown origin)				J Med Chem 58: 4839-44 (2015) Article DOI: 10.1021/jm501840b BindingDB Entry DOI: 10.7270/Q24B3314
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50233004 (2-(3-carbamimidamidopropylidene)butanedioic acid |...) Show SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]\[#6]=[#6](\[#6]-[#6](-[#8])=O)-[#6](-[#8])=O Show InChI InChI=1S/C8H13N3O4/c9-8(10)11-3-1-2-5(7(14)15)4-6(12)13/h2H,1,3-4H2,(H,12,13)(H,14,15)(H4,9,10,11)/b5-2-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Inhibition of carboxypeptidase B				Bioorg Med Chem Lett 18: 1495-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.060 BindingDB Entry DOI: 10.7270/Q2GB23T5
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120784 (US8710232, 9) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(cn2)C2CCN(C2=O)c2ccccc2)cn1 Show InChI InChI=1S/C21H21N5O3/c22-19-7-6-14(11-23-19)10-16(21(28)29)17-12-25(13-24-17)18-8-9-26(20(18)27)15-4-2-1-3-5-15/h1-7,11-13,16,18H,8-10H2,(H2,22,23)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	439	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144320 (6-Amino-2-(1H-imidazol-4-yl)-5,5-dimethyl-hexanoic...) Show SMILES CC(C)(CN)CCC(C(O)=O)c1cnc[nH]1 Show InChI InChI=1S/C11H19N3O2/c1-11(2,6-12)4-3-8(10(15)16)9-5-13-7-14-9/h5,7-8H,3-4,6,12H2,1-2H3,(H,13,14)(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120795 (US8710232, 31) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(CC#C)cn2)cn1 Show InChI InChI=1S/C14H14N4O2/c1-2-5-18-8-12(17-9-18)11(14(19)20)6-10-3-4-13(15)16-7-10/h1,3-4,7-9,11H,5-6H2,(H2,15,16)(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	870	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120793 (US8710232, 27) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(Cc3csc4ccc(Cl)cc34)cn2)cn1 Show InChI InChI=1S/C20H17ClN4O2S/c21-14-2-3-18-15(6-14)13(10-28-18)8-25-9-17(24-11-25)16(20(26)27)5-12-1-4-19(22)23-7-12/h1-4,6-7,9-11,16H,5,8H2,(H2,22,23)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120783 (US8710232, 8) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(cn2)C2CCNCC2)cn1 Show InChI InChI=1S/C16H21N5O2/c17-15-2-1-11(8-19-15)7-13(16(22)23)14-9-21(10-20-14)12-3-5-18-6-4-12/h1-2,8-10,12-13,18H,3-7H2,(H2,17,19)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120794 (US8710232, 28) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(Cc3cccc(Oc4ccc(F)cc4)c3)cn2)cn1 Show InChI InChI=1S/C24H21FN4O3/c25-18-5-7-19(8-6-18)32-20-3-1-2-17(10-20)13-29-14-22(28-15-29)21(24(30)31)11-16-4-9-23(26)27-12-16/h1-10,12,14-15,21H,11,13H2,(H2,26,27)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144322 (6-Amino-2-(1H-imidazol-4-yl)-5-methyl-hexanoic aci...) Show SMILES CC(CN)CCC(C(O)=O)c1cnc[nH]1 Show InChI InChI=1S/C10H17N3O2/c1-7(4-11)2-3-8(10(14)15)9-5-12-6-13-9/h5-8H,2-4,11H2,1H3,(H,12,13)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50144334 (6-Amino-2-(1H-imidazol-4-yl)-hexanoic acid | CHEMB...) Show SMILES NCCCCC(C(O)=O)c1cnc[nH]1 Show InChI InChI=1S/C9H15N3O2/c10-4-2-1-3-7(9(13)14)8-5-11-6-12-8/h5-7H,1-4,10H2,(H,11,12)(H,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human carboxypeptidase B (CPB)				Bioorg Med Chem Lett 14: 2141-5 (2004) Article DOI: 10.1016/j.bmcl.2004.02.033 BindingDB Entry DOI: 10.7270/Q2N8797S
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM120792 (US8710232, 25) Show SMILES Nc1ccc(CC(C(O)=O)c2cn(Cc3ccc(OC(F)(F)F)cc3)cn2)cn1 Show InChI InChI=1S/C19H17F3N4O3/c20-19(21,22)29-14-4-1-12(2-5-14)9-26-10-16(25-11-26)15(18(27)28)7-13-3-6-17(23)24-8-13/h1-6,8,10-11,15H,7,9H2,(H2,23,24)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	7.4	25
Sanofi-Aventis Deutschland GmbH US Patent					Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...				US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4
					More data for this Ligand-Target Pair