Compile Data Set for Download or QSAR

Found 2053 hits of ic50 for UniProtKB: P97612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50236330 (CHEMBL4070196) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCCCN2CCN(CC2)c2cccc(Cl)c2Cl)c1 Show InChI InChI=1S/C27H28Cl2N4O3/c28-23-9-3-10-24(25(23)29)33-15-13-32(14-16-33)12-4-11-31-27(35)36-22-8-2-6-20(18-22)19-5-1-7-21(17-19)26(30)34/h1-3,5-10,17-18H,4,11-16H2,(H2,30,34)(H,31,35)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAAH in Sprague-Dawley rat brain homogenate using arachidonoyl-ethanolamide and anandamide [ethanolamine-1-3H] as substrate pre-incubat...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111953 BindingDB Entry DOI: 10.7270/Q2BC436Z
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50447747 (CHEMBL3113272) Show SMILES Fc1ccc(F)c(c1)-c1ccnc(n1)N1CCN(CC1)C(=O)Nc1cccnn1 Show InChI InChI=1S/C19H17F2N7O/c20-13-3-4-15(21)14(12-13)16-5-7-22-18(24-16)27-8-10-28(11-9-27)19(29)25-17-2-1-6-23-26-17/h1-7,12H,8-11H2,(H,25,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assay				Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359728 (US10435355, Example 12 | US9822068, 12 | [3-(3-car...) Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359728 (US10435355, Example 12 | US9822068, 12 | [3-(3-car...) Show SMILES NC(=O)c1cccc(c1)-c1cc(F)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H21FN2O3/c21-16-10-15(13-5-4-6-14(9-13)19(22)24)11-18(12-16)26-20(25)23-17-7-2-1-3-8-17/h4-6,9-12,17H,1-3,7-8H2,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50295654 (CHEMBL559034 | Dodecylcarbamic acid 3-(1,2,3-thiad...) Show SMILES CCCCCCCCCCCCNC(=O)Oc1cccc(c1)-c1csnn1 Show InChI InChI=1S/C21H31N3O2S/c1-2-3-4-5-6-7-8-9-10-11-15-22-21(25)26-19-14-12-13-18(16-19)20-17-27-24-23-20/h12-14,16-17H,2-11,15H2,1H3,(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of FAAH in Wistar rat cerebral membrane by liquid scintillation counting				Eur J Med Chem 44: 2994-3008 (2009) Article DOI: 10.1016/j.ejmech.2009.01.007 BindingDB Entry DOI: 10.7270/Q2VT1S5S
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50447746 (CHEMBL3113273) Show SMILES Fc1ccc(cc1F)-c1ccnc(n1)N1CCN(CC1)C(=O)Nc1cccnn1 Show InChI InChI=1S/C19H17F2N7O/c20-14-4-3-13(12-15(14)21)16-5-7-22-18(24-16)27-8-10-28(11-9-27)19(29)25-17-2-1-6-23-26-17/h1-7,12H,8-11H2,(H,25,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assay				Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50551026 (CHEMBL4749527) Show SMILES CC(=O)Oc1cn(C(=O)NCCCc2ccc(cc2)-c2ccccc2)c(=O)[nH]c1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat FAAH using [3H]-AEA as substrate by liquid chromatography-mass spectrometry				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111953 BindingDB Entry DOI: 10.7270/Q2BC436Z
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437233 (CHEMBL2402911) Show SMILES CC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1O Show InChI InChI=1S/C21H23NO4/c1-14(23)15-6-5-7-16(12-15)19-13-18(10-11-20(19)24)26-21(25)22-17-8-3-2-4-9-17/h5-7,10-13,17,24H,2-4,8-9H2,1H3,(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50236334 (CHEMBL4071240) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)c1 Show InChI InChI=1S/C28H30Cl2N4O3/c29-24-10-5-11-25(26(24)30)34-16-14-33(15-17-34)13-2-1-12-32-28(36)37-23-9-4-7-21(19-23)20-6-3-8-22(18-20)27(31)35/h3-11,18-19H,1-2,12-17H2,(H2,31,35)(H,32,36)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAAH in Sprague-Dawley rat brain homogenate using arachidonoyl-ethanolamide and anandamide [ethanolamine-1-3H] as substrate pre-incubat...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111953 BindingDB Entry DOI: 10.7270/Q2BC436Z
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM23316 (7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C19H20N2O2/c22-16(19-21-18-17(23-19)13-8-14-20-18)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.316	n/a	n/a	n/a	n/a	9.0	37
FUNDP					Assay Description The effect of the test compounds on the enzymatic hydrolysis of [3H]anandamide was evaluated by using rat brain homogenate preparations. [3H]Ethanola...				Bioorg Med Chem Lett 16: 4772-6 (2006) Article DOI: 10.1016/j.bmcl.2006.06.087 BindingDB Entry DOI: 10.7270/Q2M906ZB
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50419129 (CHEMBL1830441) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCCCCc2ccccc2)c1 Show InChI InChI=1S/C24H24N2O3/c25-23(27)21-13-6-11-19(16-21)20-12-7-14-22(17-20)29-24(28)26-15-5-4-10-18-8-2-1-3-9-18/h1-3,6-9,11-14,16-17H,4-5,10,15H2,(H2,25,27)(H,26,28)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.331	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]-anandamide from rat brain FAAH after 30 mins by scintillation counting				Eur J Med Chem 46: 4466-73 (2011) Article DOI: 10.1016/j.ejmech.2011.07.021 BindingDB Entry DOI: 10.7270/Q2FB546B
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50447745 (CHEMBL3113274) Show SMILES Fc1cc(F)cc(c1)-c1ccnc(n1)N1CCN(CC1)C(=O)Nc1cccnn1 Show InChI InChI=1S/C19H17F2N7O/c20-14-10-13(11-15(21)12-14)16-3-5-22-18(24-16)27-6-8-28(9-7-27)19(29)25-17-2-1-4-23-26-17/h1-5,10-12H,6-9H2,(H,25,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assay				Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50458983 (CHEMBL4207166) Show SMILES CN(CCNC(C)=O)c1cccc(OCCCCCCNC(=O)Oc2cccc(c2)-c2cccc(O)c2)c1 Show InChI InChI=1S/C30H37N3O5/c1-23(34)31-17-18-33(2)26-12-9-14-28(22-26)37-19-6-4-3-5-16-32-30(36)38-29-15-8-11-25(21-29)24-10-7-13-27(35)20-24/h7-15,20-22,35H,3-6,16-19H2,1-2H3,(H,31,34)(H,32,36)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino "Carlo Bo" Curated by ChEMBL					Assay Description Inhibition of FAAH1 in Wistar rat brain homogenates using [3H]anandamide as substrate incubated for 30 mins by liquid scintillation counting method				J Med Chem 61: 7902-7916 (2018) Article DOI: 10.1021/acs.jmedchem.8b00893 BindingDB Entry DOI: 10.7270/Q2GX4F6V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50434329 (CHEMBL2386554) Show SMILES Cn1cc(Sc2ccc(Cl)cc2)c(n1)-c1ccc2ccc(nc2c1)C(N)=O Show InChI InChI=1S/C20H15ClN4OS/c1-25-11-18(27-15-7-5-14(21)6-8-15)19(24-25)13-3-2-12-4-9-16(20(22)26)23-17(12)10-13/h2-11H,1H3,(H2,22,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in CHO cell lysates assessed as arachidonyl-7-amino-4-methylcoumarin amide hydrolysis to 7-amino 4-methyl coumarin p...				ACS Med Chem Lett 4: 509-13 (2013) Article DOI: 10.1021/ml4000996 BindingDB Entry DOI: 10.7270/Q21R6RWJ
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50458984 (CHEMBL4218897) Show SMILES CN(CCNC(C)=O)c1cccc(OCCCCCCNC(=O)Oc2cccc(c2)-c2cccc(c2)C(N)=O)c1 Show InChI InChI=1S/C31H38N4O5/c1-23(36)33-17-18-35(2)27-13-9-14-28(22-27)39-19-6-4-3-5-16-34-31(38)40-29-15-8-11-25(21-29)24-10-7-12-26(20-24)30(32)37/h7-15,20-22H,3-6,16-19H2,1-2H3,(H2,32,37)(H,33,36)(H,34,38)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino "Carlo Bo" Curated by ChEMBL					Assay Description Inhibition of FAAH1 in Wistar rat brain homogenates using [3H]anandamide as substrate incubated for 30 mins by liquid scintillation counting method				J Med Chem 61: 7902-7916 (2018) Article DOI: 10.1021/acs.jmedchem.8b00893 BindingDB Entry DOI: 10.7270/Q2GX4F6V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50447749 (CHEMBL3113270) Show SMILES Fc1ccc(c(F)c1)-c1ccnc(n1)N1CCN(CC1)C(=O)Nc1cccnn1 Show InChI InChI=1S/C19H17F2N7O/c20-13-3-4-14(15(21)12-13)16-5-7-22-18(24-16)27-8-10-28(11-9-27)19(29)25-17-2-1-6-23-26-17/h1-7,12H,8-11H2,(H,25,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assay				Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50426652 (CHEMBL2326178) Show SMILES Cc1onc(NC(=O)N2CCN(CC2)c2nc(cs2)-c2ccc(F)cc2F)c1C Show InChI InChI=1S/C19H19F2N5O2S/c1-11-12(2)28-24-17(11)23-18(27)25-5-7-26(8-6-25)19-22-16(10-29-19)14-4-3-13(20)9-15(14)21/h3-4,9-10H,5-8H2,1-2H3,(H,23,24,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH after 30 mins				Bioorg Med Chem 21: 28-41 (2012) Article DOI: 10.1016/j.bmc.2012.11.006 BindingDB Entry DOI: 10.7270/Q2FN17H6
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM26739 (3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Max-Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of rat intact neuron FAAH				Bioorg Med Chem 20: 1100-12 (2012) Article DOI: 10.1016/j.bmc.2011.11.027 BindingDB Entry DOI: 10.7270/Q2G16191
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437231 (CHEMBL2402925) Show SMILES NC(=O)c1cccc(c1)-c1cc(O)cc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H22N2O4/c21-19(24)14-6-4-5-13(9-14)15-10-17(23)12-18(11-15)26-20(25)22-16-7-2-1-3-8-16/h4-6,9-12,16,23H,1-3,7-8H2,(H2,21,24)(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437232 (3‐(3‐carbamoylphenyl)‐4‐me...) Show SMILES COc1ccc(OC(=O)NC2CCCCC2)cc1-c1cccc(c1)C(N)=O Show InChI InChI=1S/C21H24N2O4/c1-26-19-11-10-17(27-21(25)23-16-8-3-2-4-9-16)13-18(19)14-6-5-7-15(12-14)20(22)24/h5-7,10-13,16H,2-4,8-9H2,1H3,(H2,22,24)(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM26739 (3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NC2CCCCC2)c1 Show InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FAAH in Wistar rat brain intact neurons assessed as reduction in [3H]anandamide hydrolysis using [3H]anandamide as substrate preincubat...				J Med Chem 62: 10995-11003 (2019) Article DOI: 10.1021/acs.jmedchem.9b00885 BindingDB Entry DOI: 10.7270/Q26113K2
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50424227 (CHEMBL2314112) Show SMILES CCCCCCNC(=O)Oc1cccc(c1)C1=NCCO1 |t:17| Show InChI InChI=1S/C16H22N2O3/c1-2-3-4-5-9-18-16(19)21-14-8-6-7-13(12-14)15-17-10-11-20-15/h6-8,12H,2-5,9-11H2,1H3,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
Centre for Addiction and Mental Health Curated by ChEMBL					Assay Description Inhibition of FAAH-mediated [3H]anandamide hydrolysis in rat brain homogenate assessed as [3H]ethanolamine production incubated for 90 mins prior to ...				J Med Chem 56: 201-9 (2013) Article DOI: 10.1021/jm301492y BindingDB Entry DOI: 10.7270/Q2XD130R
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50434318 (CHEMBL2386566) Show SMILES CN(C)C(=O)[C@H]1C[C@@H]1c1ccc(cc1)-c1ncn(C)c1Sc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H22ClN3OS/c1-25(2)21(27)19-12-18(19)14-4-6-15(7-5-14)20-22(26(3)13-24-20)28-17-10-8-16(23)9-11-17/h4-11,13,18-19H,12H2,1-3H3/t18-,19+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in CHO cell lysates assessed as arachidonyl-7-amino-4-methylcoumarin amide hydrolysis to 7-amino 4-methyl coumarin p...				ACS Med Chem Lett 4: 509-13 (2013) Article DOI: 10.1021/ml4000996 BindingDB Entry DOI: 10.7270/Q21R6RWJ
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50458981 (CHEMBL4206642) Show SMILES CN(CCNC(C)=O)c1cccc(OCCCCCCCCNC(=O)Oc2cccc(c2)-c2ccccc2)c1 Show InChI InChI=1S/C32H41N3O4/c1-26(36)33-21-22-35(2)29-17-13-18-30(25-29)38-23-11-6-4-3-5-10-20-34-32(37)39-31-19-12-16-28(24-31)27-14-8-7-9-15-27/h7-9,12-19,24-25H,3-6,10-11,20-23H2,1-2H3,(H,33,36)(H,34,37)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino "Carlo Bo" Curated by ChEMBL					Assay Description Inhibition of FAAH1 in Wistar rat brain homogenates using [3H]anandamide as substrate incubated for 30 mins by liquid scintillation counting method				J Med Chem 61: 7902-7916 (2018) Article DOI: 10.1021/acs.jmedchem.8b00893 BindingDB Entry DOI: 10.7270/Q2GX4F6V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50271030 (3'-carbamoylbiphenyl-3-yl naphthalen-2-ylmethylcar...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C25H20N2O3/c26-24(28)22-9-3-7-20(14-22)21-8-4-10-23(15-21)30-25(29)27-16-17-11-12-18-5-1-2-6-19(18)13-17/h1-15H,16H2,(H2,26,28)(H,27,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Parma Curated by ChEMBL					Assay Description Inhibition of FAAH in rat brain membrane assessed as [3H]anandamide hydrolysis				J Med Chem 51: 3487-98 (2008) Article DOI: 10.1021/jm701631z BindingDB Entry DOI: 10.7270/Q2TM79W9
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50271030 (3'-carbamoylbiphenyl-3-yl naphthalen-2-ylmethylcar...) Show SMILES NC(=O)c1cccc(c1)-c1cccc(OC(=O)NCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C25H20N2O3/c26-24(28)22-9-3-7-20(14-22)21-8-4-10-23(15-21)30-25(29)27-16-17-11-12-18-5-1-2-6-19(18)13-17/h1-15H,16H2,(H2,26,28)(H,27,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.631	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]-anandamide from rat brain FAAH after 30 mins by scintillation counting				Eur J Med Chem 46: 4466-73 (2011) Article DOI: 10.1016/j.ejmech.2011.07.021 BindingDB Entry DOI: 10.7270/Q2FB546B
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359718 (US10435355, Example 2 | US9822068, 2 | [4-fluoro-3...) Show SMILES NS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1F Show InChI InChI=1S/C19H21FN2O4S/c20-18-10-9-15(26-19(23)22-14-6-2-1-3-7-14)12-17(18)13-5-4-8-16(11-13)27(21,24)25/h4-5,8-12,14H,1-3,6-7H2,(H,22,23)(H2,21,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50551011 (CHEMBL4781803) Show SMILES NC(=O)c1ccc(cc1)-c1ccc(OC(=O)NCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)cc1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FAAH in Sprague-Dawley rat brain homogenate using arachidonoyl-ethanolamide and anandamide [ethanolamine-1-3H] as substrate pre-incubat...				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111953 BindingDB Entry DOI: 10.7270/Q2BC436Z
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50402675 (CHEMBL2207348) Show SMILES Clc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3noc4cnccc34)c2)cc1 Show InChI InChI=1S/C24H22ClN5O3/c25-18-4-6-19(7-5-18)32-20-3-1-2-17(14-20)16-29-10-12-30(13-11-29)24(31)27-23-21-8-9-26-15-22(21)33-28-23/h1-9,14-15H,10-13,16H2,(H,27,28,31)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research and Development, LLC Curated by ChEMBL					Assay Description Inhibition of rat FAAH preincubated for 60 mins				Bioorg Med Chem Lett 22: 7357-62 (2012) Article DOI: 10.1016/j.bmcl.2012.10.076 BindingDB Entry DOI: 10.7270/Q28S4R30
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM23078 (3-(4-phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C23H18N2O2/c26-21(23-25-16-22(27-23)20-8-4-5-15-24-20)14-11-17-9-12-19(13-10-17)18-6-2-1-3-7-18/h1-10,12-13,15-16H,11,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359718 (US10435355, Example 2 | US9822068, 2 | [4-fluoro-3...) Show SMILES NS(=O)(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1F Show InChI InChI=1S/C19H21FN2O4S/c20-18-10-9-15(26-19(23)22-14-6-2-1-3-7-14)12-17(18)13-5-4-8-16(11-13)27(21,24)25/h4-5,8-12,14H,1-3,6-7H2,(H,22,23)(H2,21,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50426650 (CHEMBL2326177) Show SMILES Cc1onc(NC(=O)N2CCN(CC2)c2nc(cs2)-c2ccc(F)cc2)c1C Show InChI InChI=1S/C19H20FN5O2S/c1-12-13(2)27-23-17(12)22-18(26)24-7-9-25(10-8-24)19-21-16(11-28-19)14-3-5-15(20)6-4-14/h3-6,11H,7-10H2,1-2H3,(H,22,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH after 30 mins				Bioorg Med Chem 21: 28-41 (2012) Article DOI: 10.1016/j.bmc.2012.11.006 BindingDB Entry DOI: 10.7270/Q2FN17H6
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50426651 (CHEMBL2326194) Show SMILES Cc1onc(NC(=O)N2CCN(CC2)c2nc(cs2)-c2ccccc2F)c1C Show InChI InChI=1S/C19H20FN5O2S/c1-12-13(2)27-23-17(12)22-18(26)24-7-9-25(10-8-24)19-21-16(11-28-19)14-5-3-4-6-15(14)20/h3-6,11H,7-10H2,1-2H3,(H,22,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH after 30 mins				Bioorg Med Chem 21: 28-41 (2012) Article DOI: 10.1016/j.bmc.2012.11.006 BindingDB Entry DOI: 10.7270/Q2FN17H6
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50551027 (CHEMBL4752215) Show SMILES CC(=O)Oc1cn(C(=O)NCCCCc2ccc(cc2)-c2ccccc2)c(=O)[nH]c1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of rat FAAH using [3H]-AEA as substrate by liquid chromatography-mass spectrometry				Citation and Details Article DOI: 10.1016/j.ejmech.2019.111953 BindingDB Entry DOI: 10.7270/Q2BC436Z
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50426648 (CHEMBL2326197) Show SMILES Cc1onc(NC(=O)N2CCN(CC2)c2nc(ns2)-c2ccc(F)cc2)c1C Show InChI InChI=1S/C18H19FN6O2S/c1-11-12(2)27-22-15(11)20-17(26)24-7-9-25(10-8-24)18-21-16(23-28-18)13-3-5-14(19)6-4-13/h3-6H,7-10H2,1-2H3,(H,20,22,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH after 30 mins				Bioorg Med Chem 21: 28-41 (2012) Article DOI: 10.1016/j.bmc.2012.11.006 BindingDB Entry DOI: 10.7270/Q2FN17H6
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50436356 (CHEMBL2396702) Show SMILES FCCCCCNC(=O)Oc1cccc(c1)C1=NCCO1 |t:17| Show InChI InChI=1S/C15H19FN2O3/c16-7-2-1-3-8-18-15(19)21-13-6-4-5-12(11-13)14-17-9-10-20-14/h4-6,11H,1-3,7-10H2,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.813	n/a	n/a	n/a	n/a	n/a	n/a
Centre for Addiction and Mental Health Curated by ChEMBL					Assay Description Inhibition of FAAH in rat brain homogenates using [3H]anandamide as substrate preincubated for 60 mins by liquid scintillation spectroscopy				Bioorg Med Chem 21: 4351-7 (2013) Article DOI: 10.1016/j.bmc.2013.04.077 BindingDB Entry DOI: 10.7270/Q2RN398F
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50436356 (CHEMBL2396702) Show SMILES FCCCCCNC(=O)Oc1cccc(c1)C1=NCCO1 |t:17| Show InChI InChI=1S/C15H19FN2O3/c16-7-2-1-3-8-18-15(19)21-13-6-4-5-12(11-13)14-17-9-10-20-14/h4-6,11H,1-3,7-10H2,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
Centre for Addiction and Mental Health Curated by ChEMBL					Assay Description Inhibition of FAAH in rat brain homogenates using [3H]anandamide as substrate preincubated for 60 mins by liquid scintillation spectroscopy				Bioorg Med Chem 21: 4351-7 (2013) Article DOI: 10.1016/j.bmc.2013.04.077 BindingDB Entry DOI: 10.7270/Q2RN398F
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50458979 (CHEMBL4210086) Show SMILES CC(=O)NCCc1c(Br)[nH]c2ccc(OCCCCCCNC(=O)Oc3cccc(c3)-c3ccccc3)cc12 Show InChI InChI=1S/C31H34BrN3O4/c1-22(36)33-18-16-27-28-21-25(14-15-29(28)35-30(27)32)38-19-8-3-2-7-17-34-31(37)39-26-13-9-12-24(20-26)23-10-5-4-6-11-23/h4-6,9-15,20-21,35H,2-3,7-8,16-19H2,1H3,(H,33,36)(H,34,37)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino "Carlo Bo" Curated by ChEMBL					Assay Description Inhibition of FAAH1 in Wistar rat brain homogenates using [3H]anandamide as substrate incubated for 30 mins by liquid scintillation counting method				J Med Chem 61: 7902-7916 (2018) Article DOI: 10.1021/acs.jmedchem.8b00893 BindingDB Entry DOI: 10.7270/Q2GX4F6V
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359719 (US10435355, Example 3 | US9822068, 3 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCC2)ccc1F Show InChI InChI=1S/C18H17FN2O3/c19-16-8-7-14(24-18(23)21-13-5-2-6-13)10-15(16)11-3-1-4-12(9-11)17(20)22/h1,3-4,7-10,13H,2,5-6H2,(H2,20,22)(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California; Fondazione Istituto Italiano di Technologia US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US9822068 (2017) BindingDB Entry DOI: 10.7270/Q2Q242HW
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM359719 (US10435355, Example 3 | US9822068, 3 | [3-(3-carba...) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCC2)ccc1F Show InChI InChI=1S/C18H17FN2O3/c19-16-8-7-14(24-18(23)21-13-5-2-6-13)10-15(16)11-3-1-4-12(9-11)17(20)22/h1,3-4,7-10,13H,2,5-6H2,(H2,20,22)(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description Rat FAAH was prepared from male Sprague Dawley rat brains, homogenized in a potter in 20 mM of Tris HCl pH 7.4, 0.32 M sucrose.The radiometric assay ...				US Patent US10435355 (2019) BindingDB Entry DOI: 10.7270/Q29C70TM
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50426649 (CHEMBL2326192) Show SMILES Cc1onc(NC(=O)N2CCN(CC2)c2nc(cs2)-c2ccccc2)c1C Show InChI InChI=1S/C19H21N5O2S/c1-13-14(2)26-22-17(13)21-18(25)23-8-10-24(11-9-23)19-20-16(12-27-19)15-6-4-3-5-7-15/h3-7,12H,8-11H2,1-2H3,(H,21,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.960	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH after 30 mins				Bioorg Med Chem 21: 28-41 (2012) Article DOI: 10.1016/j.bmc.2012.11.006 BindingDB Entry DOI: 10.7270/Q2FN17H6
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50228837 (2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...) Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)C#N Show InChI InChI=1S/C19H14N2O2/c20-12-17-13-21-19(23-17)18(22)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-7,9-10,13H,8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli				J Med Chem 51: 937-47 (2008) Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50262135 (1-(1,3,4-Oxadiazol-2-yl)-7-phenylheptan-1-one | CH...) Show SMILES O=C(CCCCCCc1ccccc1)c1nnco1 Show InChI InChI=1S/C15H18N2O2/c18-14(15-17-16-12-19-15)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in Escherichia coli				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50161511 (1-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-heptan-1-o...) Show SMILES O=C(CCCCCCc1ccccc1)c1nnc(o1)-c1ccco1 Show InChI InChI=1S/C19H20N2O3/c22-16(18-20-21-19(24-18)17-13-8-14-23-17)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in Escherichia coli				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50447748 (CHEMBL3113271) Show SMILES Fc1cccc(c1F)-c1ccnc(n1)N1CCN(CC1)C(=O)Nc1cccnn1 Show InChI InChI=1S/C19H17F2N7O/c20-14-4-1-3-13(17(14)21)15-6-8-22-18(24-15)27-9-11-28(12-10-27)19(29)25-16-5-2-7-23-26-16/h1-8H,9-12H2,(H,25,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assay				Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50426645 (CHEMBL2326193) Show SMILES Cc1onc(NC(=O)N2CCN(CC2)c2nc(ns2)-c2ccccc2F)c1C Show InChI InChI=1S/C18H19FN6O2S/c1-11-12(2)27-22-15(11)20-17(26)24-7-9-25(10-8-24)18-21-16(23-28-18)13-5-3-4-6-14(13)19/h3-6H,7-10H2,1-2H3,(H,20,22,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH after 30 mins				Bioorg Med Chem 21: 28-41 (2012) Article DOI: 10.1016/j.bmc.2012.11.006 BindingDB Entry DOI: 10.7270/Q2FN17H6
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50424227 (CHEMBL2314112) Show SMILES CCCCCCNC(=O)Oc1cccc(c1)C1=NCCO1 |t:17| Show InChI InChI=1S/C16H22N2O3/c1-2-3-4-5-9-18-16(19)21-14-8-6-7-13(12-14)15-17-10-11-20-15/h6-8,12H,2-5,9-11H2,1H3,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Centre for Addiction and Mental Health Curated by ChEMBL					Assay Description Inhibition of FAAH-mediated [3H]anandamide hydrolysis in rat brain homogenate assessed as [3H]ethanolamine production incubated for 45 mins prior to ...				J Med Chem 56: 201-9 (2013) Article DOI: 10.1021/jm301492y BindingDB Entry DOI: 10.7270/Q2XD130R
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50298655 (3-(4,5-Dihydrooxazol-2-yl)phenyl cyclohexylcarbama...) Show SMILES O=C(NC1CCCCC1)Oc1cccc(c1)C1=NCCO1 |t:18| Show InChI InChI=1S/C16H20N2O3/c19-16(18-13-6-2-1-3-7-13)21-14-8-4-5-12(11-14)15-17-9-10-20-15/h4-5,8,11,13H,1-3,6-7,9-10H2,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Helsinki University of Technology Curated by ChEMBL					Assay Description Inhibition of FAAH in Wistar rat brain assessed as by liquid scintillation counting				Eur J Med Chem 44: 4179-91 (2009) Article DOI: 10.1016/j.ejmech.2009.05.012 BindingDB Entry DOI: 10.7270/Q2FT8M3R
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50437230 (CHEMBL2402922) Show SMILES NC(=O)c1cccc(c1)-c1cc(OC(=O)NC2CCCCC2)ccc1CO Show InChI InChI=1S/C21H24N2O4/c22-20(25)15-6-4-5-14(11-15)19-12-18(10-9-16(19)13-24)27-21(26)23-17-7-2-1-3-8-17/h4-6,9-12,17,24H,1-3,7-8,13H2,(H2,22,25)(H,23,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...				J Med Chem 56: 5917-30 (2014) Article DOI: 10.1021/jm4007017 BindingDB Entry DOI: 10.7270/Q2KP83KP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50458982 (CHEMBL4211530) Show SMILES CN(CCNC(C)=O)c1cccc(OCCCCCCNC(=O)Oc2cccc(c2)-c2ccccc2)c1 Show InChI InChI=1S/C30H37N3O4/c1-24(34)31-19-20-33(2)27-15-11-16-28(23-27)36-21-9-4-3-8-18-32-30(35)37-29-17-10-14-26(22-29)25-12-6-5-7-13-25/h5-7,10-17,22-23H,3-4,8-9,18-21H2,1-2H3,(H,31,34)(H,32,35)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino "Carlo Bo" Curated by ChEMBL					Assay Description Inhibition of FAAH1 in Wistar rat brain homogenates using [3H]anandamide as substrate incubated for 30 mins by liquid scintillation counting method				J Med Chem 61: 7902-7916 (2018) Article DOI: 10.1021/acs.jmedchem.8b00893 BindingDB Entry DOI: 10.7270/Q2GX4F6V
					More data for this Ligand-Target Pair

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