Compile Data Set for Download or QSAR

Found 40 hits Enz. Inhib. hit(s) with all data for entry = 6001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103938 (US8569511, 1) Show SMILES FC1(F)CC1C(=O)Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCOCC3)c2c1 Show InChI InChI=1S/C22H20F2N6O2/c23-22(24)11-15(22)21(31)25-12-1-3-16-14(9-12)19(29-28-16)20-26-17-4-2-13(10-18(17)27-20)30-5-7-32-8-6-30/h1-4,9-10,15H,5-8,11H2,(H,25,31)(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103939 (US8569511, 2) Show SMILES CC1CN(CCO1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccc(NC(=O)C3CC3(F)F)cc12 Show InChI InChI=1S/C23H22F2N6O2/c1-12-11-31(6-7-33-12)14-3-5-18-19(9-14)28-21(27-18)20-15-8-13(2-4-17(15)29-30-20)26-22(32)16-10-23(16,24)25/h2-5,8-9,12,16H,6-7,10-11H2,1H3,(H,26,32)(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103938 (US8569511, 1) Show SMILES FC1(F)CC1C(=O)Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCOCC3)c2c1 Show InChI InChI=1S/C22H20F2N6O2/c23-22(24)11-15(22)21(31)25-12-1-3-16-14(9-12)19(29-28-16)20-26-17-4-2-13(10-18(17)27-20)30-5-7-32-8-6-30/h1-4,9-10,15H,5-8,11H2,(H,25,31)(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103939 (US8569511, 2) Show SMILES CC1CN(CCO1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccc(NC(=O)C3CC3(F)F)cc12 Show InChI InChI=1S/C23H22F2N6O2/c1-12-11-31(6-7-33-12)14-3-5-18-19(9-14)28-21(27-18)20-15-8-13(2-4-17(15)29-30-20)26-22(32)16-10-23(16,24)25/h2-5,8-9,12,16H,6-7,10-11H2,1H3,(H,26,32)(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	159	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103919 (US8569511, 3) Show SMILES O=C(Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCOCC3)c2c1)C1CC1 Show InChI InChI=1S/C22H22N6O2/c29-22(13-1-2-13)23-14-3-5-17-16(11-14)20(27-26-17)21-24-18-6-4-15(12-19(18)25-21)28-7-9-30-10-8-28/h3-6,11-13H,1-2,7-10H2,(H,23,29)(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103920 (US8569511, 4) Show SMILES FC1(F)CCC(CC1)C(=O)Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCOCC3)c2c1 Show InChI InChI=1S/C25H26F2N6O2/c26-25(27)7-5-15(6-8-25)24(34)28-16-1-3-19-18(13-16)22(32-31-19)23-29-20-4-2-17(14-21(20)30-23)33-9-11-35-12-10-33/h1-4,13-15H,5-12H2,(H,28,34)(H,29,30)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103924 (US8569511, 8) Show SMILES FC1(F)CC1C(=O)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C18H13F2N5O/c19-18(20)8-11(18)17(26)21-9-5-6-12-10(7-9)15(25-24-12)16-22-13-3-1-2-4-14(13)23-16/h1-7,11H,8H2,(H,21,26)(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103919 (US8569511, 3) Show SMILES O=C(Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCOCC3)c2c1)C1CC1 Show InChI InChI=1S/C22H22N6O2/c29-22(13-1-2-13)23-14-3-5-17-16(11-14)20(27-26-17)21-24-18-6-4-15(12-19(18)25-21)28-7-9-30-10-8-28/h3-6,11-13H,1-2,7-10H2,(H,23,29)(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103920 (US8569511, 4) Show SMILES FC1(F)CCC(CC1)C(=O)Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCOCC3)c2c1 Show InChI InChI=1S/C25H26F2N6O2/c26-25(27)7-5-15(6-8-25)24(34)28-16-1-3-19-18(13-16)22(32-31-19)23-29-20-4-2-17(14-21(20)30-23)33-9-11-35-12-10-33/h1-4,13-15H,5-12H2,(H,28,34)(H,29,30)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103926 (US8569511, 10) Show SMILES FC1(F)CC1C(=O)Nc1cccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCOCC3)c12 Show InChI InChI=1S/C22H20F2N6O2/c23-22(24)11-13(22)21(31)27-15-2-1-3-16-18(15)19(29-28-16)20-25-14-5-4-12(10-17(14)26-20)30-6-8-32-9-7-30/h1-5,10,13H,6-9,11H2,(H,25,26)(H,27,31)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	385	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103922 (US8569511, 6) Show SMILES FC1(F)CCC(CC1)C(=O)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C21H19F2N5O/c22-21(23)9-7-12(8-10-21)20(29)24-13-5-6-15-14(11-13)18(28-27-15)19-25-16-3-1-2-4-17(16)26-19/h1-6,11-12H,7-10H2,(H,24,29)(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103921 (US8569511, 5) Show SMILES CC1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccc(NC(=O)C3CC3(F)F)cc12 Show InChI InChI=1S/C24H24F2N6O/c1-13-6-8-32(9-7-13)15-3-5-19-20(11-15)29-22(28-19)21-16-10-14(2-4-18(16)30-31-21)27-23(33)17-12-24(17,25)26/h2-5,10-11,13,17H,6-9,12H2,1H3,(H,27,33)(H,28,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103928 (US8569511, 12) Show SMILES O=C(NC1CC1)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C18H16N6O/c25-18(19-10-5-6-10)20-11-7-8-13-12(9-11)16(24-23-13)17-21-14-3-1-2-4-15(14)22-17/h1-4,7-10H,5-6H2,(H,21,22)(H,23,24)(H2,19,20,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103925 (US8569511, 9) Show SMILES FC1(F)CC1C(=O)Nc1ccc2[nH]nc(-c3nc4ccc(CN5CCOCC5)cc4[nH]3)c2c1 Show InChI InChI=1S/C23H22F2N6O2/c24-23(25)11-16(23)22(32)26-14-2-4-17-15(10-14)20(30-29-17)21-27-18-3-1-13(9-19(18)28-21)12-31-5-7-33-8-6-31/h1-4,9-10,16H,5-8,11-12H2,(H,26,32)(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103923 (US8569511, 7) Show SMILES O=C(Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1)C1CC1 Show InChI InChI=1S/C18H15N5O/c24-18(10-5-6-10)19-11-7-8-13-12(9-11)16(23-22-13)17-20-14-3-1-2-4-15(14)21-17/h1-4,7-10H,5-6H2,(H,19,24)(H,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103922 (US8569511, 6) Show SMILES FC1(F)CCC(CC1)C(=O)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C21H19F2N5O/c22-21(23)9-7-12(8-10-21)20(29)24-13-5-6-15-14(11-13)18(28-27-15)19-25-16-3-1-2-4-17(16)26-19/h1-6,11-12H,7-10H2,(H,24,29)(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103923 (US8569511, 7) Show SMILES O=C(Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1)C1CC1 Show InChI InChI=1S/C18H15N5O/c24-18(10-5-6-10)19-11-7-8-13-12(9-11)16(23-22-13)17-20-14-3-1-2-4-15(14)21-17/h1-4,7-10H,5-6H2,(H,19,24)(H,20,21)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103924 (US8569511, 8) Show SMILES FC1(F)CC1C(=O)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C18H13F2N5O/c19-18(20)8-11(18)17(26)21-9-5-6-12-10(7-9)15(25-24-12)16-22-13-3-1-2-4-14(13)23-16/h1-7,11H,8H2,(H,21,26)(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103925 (US8569511, 9) Show SMILES FC1(F)CC1C(=O)Nc1ccc2[nH]nc(-c3nc4ccc(CN5CCOCC5)cc4[nH]3)c2c1 Show InChI InChI=1S/C23H22F2N6O2/c24-23(25)11-16(23)22(32)26-14-2-4-17-15(10-14)20(30-29-17)21-27-18-3-1-13(9-19(18)28-21)12-31-5-7-33-8-6-31/h1-4,9-10,16H,5-8,11-12H2,(H,26,32)(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103926 (US8569511, 10) Show SMILES FC1(F)CC1C(=O)Nc1cccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCOCC3)c12 Show InChI InChI=1S/C22H20F2N6O2/c23-22(24)11-13(22)21(31)27-15-2-1-3-16-18(15)19(29-28-16)20-25-14-5-4-12(10-17(14)26-20)30-6-8-32-9-7-30/h1-5,10,13H,6-9,11H2,(H,25,26)(H,27,31)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103932 (US8569511, 16) Show SMILES CC(C)([N+]#[C-])c1ccc(cc1)-c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C24H19N5/c1-24(2,25-3)17-11-8-15(9-12-17)16-10-13-19-18(14-16)22(29-28-19)23-26-20-6-4-5-7-21(20)27-23/h4-14H,1-2H3,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103929 (US8569511, 13) Show SMILES Fc1cccc(c1)C(=O)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C21H14FN5O/c22-13-5-3-4-12(10-13)21(28)23-14-8-9-16-15(11-14)19(27-26-16)20-24-17-6-1-2-7-18(17)25-20/h1-11H,(H,23,28)(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103927 (US8569511, 11) Show SMILES Brc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C14H9BrN4/c15-8-5-6-10-9(7-8)13(19-18-10)14-16-11-3-1-2-4-12(11)17-14/h1-7H,(H,16,17)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103928 (US8569511, 12) Show SMILES O=C(NC1CC1)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C18H16N6O/c25-18(19-10-5-6-10)20-11-7-8-13-12(9-11)16(24-23-13)17-21-14-3-1-2-4-15(14)22-17/h1-4,7-10H,5-6H2,(H,21,22)(H,23,24)(H2,19,20,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103934 (US8569511, 18) Show SMILES CN1CCC(C)(CC1)C(=O)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C22H24N6O/c1-22(9-11-28(2)12-10-22)21(29)23-14-7-8-16-15(13-14)19(27-26-16)20-24-17-5-3-4-6-18(17)25-20/h3-8,13H,9-12H2,1-2H3,(H,23,29)(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103930 (US8569511, 14) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C21H16N4O2S/c1-28(26,27)15-6-4-5-13(11-15)14-9-10-17-16(12-14)20(25-24-17)21-22-18-7-2-3-8-19(18)23-21/h2-12H,1H3,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103929 (US8569511, 13) Show SMILES Fc1cccc(c1)C(=O)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C21H14FN5O/c22-13-5-3-4-12(10-13)21(28)23-14-8-9-16-15(11-14)19(27-26-16)20-24-17-6-1-2-7-18(17)25-20/h1-11H,(H,23,28)(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103930 (US8569511, 14) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C21H16N4O2S/c1-28(26,27)15-6-4-5-13(11-15)14-9-10-17-16(12-14)20(25-24-17)21-22-18-7-2-3-8-19(18)23-21/h2-12H,1H3,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103931 (US8569511, 15) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C21H13F3N4/c22-21(23,24)14-5-3-4-12(10-14)13-8-9-16-15(11-13)19(28-27-16)20-25-17-6-1-2-7-18(17)26-20/h1-11H,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103935 (US8569511, 19) Show SMILES O=C(NC1CCCC1)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C20H20N6O/c27-20(21-12-5-1-2-6-12)22-13-9-10-15-14(11-13)18(26-25-15)19-23-16-7-3-4-8-17(16)24-19/h3-4,7-12H,1-2,5-6H2,(H,23,24)(H,25,26)(H2,21,22,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103931 (US8569511, 15) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C21H13F3N4/c22-21(23,24)14-5-3-4-12(10-14)13-8-9-16-15(11-13)19(28-27-16)20-25-17-6-1-2-7-18(17)26-20/h1-11H,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103932 (US8569511, 16) Show SMILES CC(C)([N+]#[C-])c1ccc(cc1)-c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C24H19N5/c1-24(2,25-3)17-11-8-15(9-12-17)16-10-13-19-18(14-16)22(29-28-19)23-26-20-6-4-5-7-21(20)27-23/h4-14H,1-2H3,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103936 (US8569511, 20) Show SMILES O=C(Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1)C1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C25H23N7O/c33-25(16-9-13-32(14-10-16)18-7-11-26-12-8-18)27-17-5-6-20-19(15-17)23(31-30-20)24-28-21-3-1-2-4-22(21)29-24/h1-8,11-12,15-16H,9-10,13-14H2,(H,27,33)(H,28,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103933 (US8569511, 17) Show SMILES Fc1ccc(NC(=O)Nc2ccc3[nH]nc(-c4nc5ccccc5[nH]4)c3c2)c(F)c1 Show InChI InChI=1S/C21H14F2N6O/c22-11-5-7-16(14(23)9-11)27-21(30)24-12-6-8-15-13(10-12)19(29-28-15)20-25-17-3-1-2-4-18(17)26-20/h1-10H,(H,25,26)(H,28,29)(H2,24,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103937 (US8569511, 21) Show SMILES FC1(F)CC1C(=O)Nc1ccc2c(n[nH]c2c1)-c1nc2ccc(cc2[nH]1)N1CCOCC1 Show InChI InChI=1S/C22H20F2N6O2/c23-22(24)11-15(22)21(31)25-12-1-3-14-17(9-12)28-29-19(14)20-26-16-4-2-13(10-18(16)27-20)30-5-7-32-8-6-30/h1-4,9-10,15H,5-8,11H2,(H,25,31)(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103937 (US8569511, 21) Show SMILES FC1(F)CC1C(=O)Nc1ccc2c(n[nH]c2c1)-c1nc2ccc(cc2[nH]1)N1CCOCC1 Show InChI InChI=1S/C22H20F2N6O2/c23-22(24)11-15(22)21(31)25-12-1-3-14-17(9-12)28-29-19(14)20-26-16-4-2-13(10-18(16)27-20)30-5-7-32-8-6-30/h1-4,9-10,15H,5-8,11H2,(H,25,31)(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103935 (US8569511, 19) Show SMILES O=C(NC1CCCC1)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C20H20N6O/c27-20(21-12-5-1-2-6-12)22-13-9-10-15-14(11-13)18(26-25-15)19-23-16-7-3-4-8-17(16)24-19/h3-4,7-12H,1-2,5-6H2,(H,23,24)(H,25,26)(H2,21,22,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103934 (US8569511, 18) Show SMILES CN1CCC(C)(CC1)C(=O)Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1 Show InChI InChI=1S/C22H24N6O/c1-22(9-11-28(2)12-10-22)21(29)23-14-7-8-16-15(13-14)19(27-26-16)20-24-17-5-3-4-6-18(17)25-20/h3-8,13H,9-12H2,1-2H3,(H,23,29)(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103933 (US8569511, 17) Show SMILES Fc1ccc(NC(=O)Nc2ccc3[nH]nc(-c4nc5ccccc5[nH]4)c3c2)c(F)c1 Show InChI InChI=1S/C21H14F2N6O/c22-11-5-7-16(14(23)9-11)27-21(30)24-12-6-8-15-13(10-12)19(29-28-15)20-25-17-3-1-2-4-18(17)26-20/h1-10H,(H,25,26)(H,28,29)(H2,24,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM103936 (US8569511, 20) Show SMILES O=C(Nc1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1)C1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C25H23N7O/c33-25(16-9-13-32(14-10-16)18-7-11-26-12-8-18)27-17-5-6-20-19(15-17)23(31-30-20)24-28-21-3-1-2-4-22(21)29-24/h1-8,11-12,15-16H,9-10,13-14H2,(H,27,33)(H,28,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Utah Research Foundation US Patent					Assay Description The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.				US Patent US8569511 (2013) BindingDB Entry DOI: 10.7270/Q2T1528Q
					More data for this Ligand-Target Pair