Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1D (GUINEA PIG) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1B receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (GUINEA PIG) | BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 1D receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1C receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (GUINEA PIG) | BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1D receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1C receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1A receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1C receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (GUINEA PIG) | BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1D receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1B receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [125I]DOI as radioligand. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1B receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1C receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM30707 (2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ket as radioligand. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1B receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (RAT-Rattus norvegicus (Rat)-Rattus norvegicus (rat...) | BDBM50081702 (5-Methoxy-3-((S)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Binding affinity of the compound against 5-hydroxytryptamine 1D receptor | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-hydroxytryptamine 1A receptor of guinea pig hippocampus. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (GUINEA PIG) | BDBM50081704 (5-Methoxy-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (GUINEA PIG) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a |
Pfizer, Inc Curated by ChEMBL | Assay Description Effect of the compound on forskolin stimulated adenylate cyclase activity at 5-HT1D receptor of guinea pig substantia nigra. | J Med Chem 35: 4503-5 (1992) BindingDB Entry DOI: 10.7270/Q29C6WC5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |