Compile Data Set for Download or QSAR

Found 32 hits Enz. Inhib. hit(s) with all data for entry = 50013646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132898 (CHEMBL115142 | Dibutyl-[3-(2,4-dichloro-phenyl)-1,...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H28Cl2N4/c1-5-7-11-28(12-8-6-2)19-13-15(3)25-21-20(26-27(4)22(19)21)17-10-9-16(23)14-18(17)24/h9-10,13-14H,5-8,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132901 (CHEMBL445075 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H24Cl2N4/c1-4-9-27(12-14-5-6-14)18-10-13(2)24-20-19(25-26(3)21(18)20)16-8-7-15(22)11-17(16)23/h7-8,10-11,14H,4-6,9,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132907 (CHEMBL112152 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(nn(CC)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H26Cl2N4/c1-4-10-27(13-15-6-7-15)19-11-14(3)25-21-20(26-28(5-2)22(19)21)17-9-8-16(23)12-18(17)24/h8-9,11-12,15H,4-7,10,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132892 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4/c1-5-7-10-26(6-2)17-11-13(3)23-19-18(24-25(4)20(17)19)15-9-8-14(21)12-16(15)22/h8-9,11-12H,5-7,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132902 (CHEMBL114861 | Dibutyl-[3-(2,4-dichloro-phenyl)-1-...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(CC)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H30Cl2N4/c1-5-8-12-28(13-9-6-2)20-14-16(4)26-22-21(27-29(7-3)23(20)22)18-11-10-17(24)15-19(18)25/h10-11,14-15H,5-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132896 (CHEMBL114193 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...) Show SMILES CCCN(CCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4/c1-5-9-26(10-6-2)17-11-13(3)23-19-18(24-25(4)20(17)19)15-8-7-14(21)12-16(15)22/h7-8,11-12H,5-6,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132904 (Butyl-[3-(2,4-dichloro-phenyl)-1-ethyl-5-methyl-1H...) Show SMILES CCCCN(CC)c1cc(C)nc2c(nn(CC)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H26Cl2N4/c1-5-8-11-26(6-2)18-12-14(4)24-20-19(25-27(7-3)21(18)20)16-10-9-15(22)13-17(16)23/h9-10,12-13H,5-8,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132899 (CHEMBL334039 | [3-(2,4-Dichloro-phenyl)-2,5-dimeth...) Show SMILES CCCN(CCC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 |(8.04,5.07,;8.6,3.62,;7.63,2.42,;8.19,1,;9.71,.75,;10.69,1.96,;12.21,1.72,;7.21,-.22,;7.79,-1.64,;6.81,-2.85,;7.37,-4.29,;5.29,-2.62,;4.73,-1.18,;3.28,-.64,;2.04,-1.54,;2.21,-3.07,;.96,-3.98,;-.46,-3.35,;-1.71,-4.26,;-.62,-1.82,;.64,-.91,;.48,.63,;3.35,.88,;2.15,1.84,;4.84,1.3,;5.69,.02,)| Show InChI InChI=1S/C20H24Cl2N4/c1-5-9-26(10-6-2)17-11-13(3)23-19-18(17)24-25(4)20(19)15-8-7-14(21)12-16(15)22/h7-8,11-12H,5-6,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP production				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132894 (CHEMBL334262 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 |(8.04,5.07,;8.6,3.62,;7.63,2.42,;8.19,1,;9.71,.75,;10.69,1.96,;12.21,1.72,;10.12,3.39,;7.21,-.22,;7.79,-1.64,;6.81,-2.85,;7.37,-4.29,;5.29,-2.62,;4.73,-1.18,;3.28,-.64,;2.04,-1.54,;2.21,-3.07,;.96,-3.98,;-.46,-3.35,;-1.71,-4.26,;-.62,-1.82,;.64,-.91,;.48,.63,;3.35,.88,;2.15,1.84,;4.84,1.3,;5.69,.02,)| Show InChI InChI=1S/C21H24Cl2N4/c1-4-9-27(12-14-5-6-14)18-10-13(2)24-20-19(18)25-26(3)21(20)16-8-7-15(22)11-17(16)23/h7-8,10-11,14H,4-6,9,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132885 (CHEMBL112151 | Dibutyl-[3-(2,4-dichloro-phenyl)-1-...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C(C)C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H32Cl2N4/c1-6-8-12-29(13-9-7-2)21-14-17(5)27-23-22(28-30(16(3)4)24(21)23)19-11-10-18(25)15-20(19)26/h10-11,14-16H,6-9,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132890 (CHEMBL420681 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(n[nH]c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H22Cl2N4/c1-3-8-26(11-13-4-5-13)17-9-12(2)23-20-18(24-25-19(17)20)15-7-6-14(21)10-16(15)22/h6-7,9-10,13H,3-5,8,11H2,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132887 (CHEMBL115313 | Dibutyl-[2,5-dimethyl-3-(2,4,6-trim...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(-c3c(C)cc(C)cc3C)n(C)nc12 |(16.55,-8.33,;16.01,-6.88,;14.49,-6.64,;13.93,-5.21,;12.41,-4.96,;11.85,-3.54,;12.81,-2.34,;12.25,-.9,;10.73,-.66,;11.43,-6.18,;11.99,-7.6,;11.04,-8.81,;11.6,-10.24,;9.51,-8.58,;8.95,-7.13,;7.51,-6.6,;6.27,-7.48,;4.86,-6.87,;4.68,-5.34,;3.61,-7.78,;3.77,-9.31,;2.52,-10.22,;5.17,-9.94,;6.43,-9.03,;7.85,-9.66,;7.58,-5.08,;6.36,-4.12,;9.05,-4.66,;9.91,-5.94,)| Show InChI InChI=1S/C25H36N4/c1-8-10-12-29(13-11-9-2)21-16-20(6)26-24-23(21)27-28(7)25(24)22-18(4)14-17(3)15-19(22)5/h14-16H,8-13H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132900 (CHEMBL114821 | [3-(2-Chloro-4-methyl-phenyl)-2-eth...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(-c3ccc(C)cc3Cl)n(CC)nc12 |(8.86,4.53,;9.42,3.1,;8.46,1.89,;9.02,.46,;10.54,.23,;11.1,-1.22,;12.62,-1.46,;10.13,-2.41,;8.05,-.75,;8.61,-2.18,;7.65,-3.37,;8.21,-4.82,;6.12,-3.14,;5.56,-1.71,;4.12,-1.17,;2.88,-2.06,;3.05,-3.61,;1.78,-4.52,;.38,-3.89,;-.86,-4.79,;.22,-2.36,;1.47,-1.43,;1.31,.09,;4.19,.35,;2.98,1.31,;3.21,2.84,;5.66,.76,;6.52,-.51,)| Show InChI InChI=1S/C23H29ClN4/c1-5-11-27(14-17-8-9-17)20-13-16(4)25-22-21(20)26-28(6-2)23(22)18-10-7-15(3)12-19(18)24/h7,10,12-13,17H,5-6,8-9,11,14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132888 (Butyl-[3-(2,4-dichloro-phenyl)-2-ethyl-5-methyl-2H...) Show SMILES CCCCN(CC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(CC)nc12 |(8.98,6.26,;8.02,5.05,;8.58,3.61,;7.61,2.42,;8.17,.99,;9.68,.75,;10.65,1.95,;7.19,-.22,;7.76,-1.64,;6.79,-2.84,;7.35,-4.27,;5.28,-2.61,;4.72,-1.17,;3.27,-.64,;2.04,-1.54,;2.2,-3.06,;.96,-3.97,;-.46,-3.34,;-1.7,-4.25,;-.62,-1.82,;.64,-.91,;.47,.63,;3.34,.88,;2.14,1.83,;2.38,3.36,;4.82,1.3,;5.67,.02,)| Show InChI InChI=1S/C21H26Cl2N4/c1-5-8-11-26(6-2)18-12-14(4)24-20-19(18)25-27(7-3)21(20)16-10-9-15(22)13-17(16)23/h9-10,12-13H,5-8,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132889 (CHEMBL116167 | Dibutyl-[3-(2,4-dichloro-phenyl)-2,...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 |(14.42,2.44,;13.46,1.25,;11.94,1.47,;10.97,.27,;9.45,.51,;8.89,1.95,;9.86,3.14,;9.3,4.59,;10.27,5.78,;8.47,-.68,;9.05,-2.12,;8.08,-3.32,;8.64,-4.76,;6.56,-3.09,;6,-1.66,;4.56,-1.1,;3.32,-2.01,;3.48,-3.54,;2.24,-4.45,;.82,-3.82,;-.42,-4.73,;.66,-2.29,;1.92,-1.38,;1.76,.16,;4.62,.41,;3.43,1.37,;6.11,.82,;6.96,-.45,)| Show InChI InChI=1S/C22H28Cl2N4/c1-5-7-11-28(12-8-6-2)19-13-15(3)25-21-20(19)26-27(4)22(21)17-10-9-16(23)14-18(17)24/h9-10,13-14H,5-8,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132910 (CHEMBL116280 | Dibutyl-[3-(2,4-dichloro-phenyl)-2-...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(CC)nc12 |(6.49,5.28,;8.02,5.05,;8.58,3.61,;7.61,2.42,;8.17,.99,;9.68,.75,;10.65,1.95,;12.17,1.72,;12.73,.28,;7.19,-.22,;7.76,-1.64,;6.79,-2.84,;7.35,-4.27,;5.28,-2.61,;4.72,-1.17,;3.27,-.64,;2.04,-1.54,;2.2,-3.06,;.96,-3.97,;-.46,-3.34,;-1.7,-4.25,;-.62,-1.82,;.64,-.91,;.47,.63,;3.34,.88,;2.14,1.83,;2.38,3.36,;4.82,1.3,;5.67,.02,)| Show InChI InChI=1S/C23H30Cl2N4/c1-5-8-12-28(13-9-6-2)20-14-16(4)26-22-21(20)27-29(7-3)23(22)18-11-10-17(24)15-19(18)25/h10-11,14-15H,5-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132906 (Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyr...) Show SMILES CCCCN(CC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 |(8.98,6.26,;8.02,5.05,;8.58,3.61,;7.61,2.42,;8.17,.99,;9.68,.75,;10.65,1.95,;7.19,-.22,;7.76,-1.64,;6.79,-2.84,;7.35,-4.27,;5.28,-2.61,;4.72,-1.17,;3.27,-.64,;2.04,-1.54,;2.2,-3.06,;.96,-3.97,;-.46,-3.34,;-1.7,-4.25,;-.62,-1.82,;.64,-.91,;.47,.63,;3.34,.88,;2.14,1.83,;4.82,1.3,;5.67,.02,)| Show InChI InChI=1S/C20H24Cl2N4/c1-5-7-10-26(6-2)17-11-13(3)23-19-18(17)24-25(4)20(19)15-9-8-14(21)12-16(15)22/h8-9,11-12H,5-7,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132905 (CHEMBL269690 | Dibutyl-[3-(2,4-dichloro-phenyl)-2-...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(nc12)C(C)C |(13.19,1.53,;12.21,.33,;10.7,.56,;9.74,-.64,;8.21,-.4,;7.65,1.03,;8.63,2.23,;8.07,3.65,;9.02,4.86,;7.24,-1.61,;7.81,-3.04,;6.85,-4.22,;7.41,-5.67,;5.32,-3.99,;4.76,-2.57,;3.33,-2.03,;2.1,-2.92,;2.26,-4.46,;1.01,-5.37,;-.4,-4.74,;-1.65,-5.65,;-.56,-3.21,;.68,-2.29,;.54,-.75,;3.4,-.51,;4.88,-.1,;5.72,-1.37,;2.2,.44,;2.43,1.97,;.77,-.12,)| Show InChI InChI=1S/C24H32Cl2N4/c1-6-8-12-29(13-9-7-2)21-14-17(5)27-23-22(21)28-30(16(3)4)24(23)19-11-10-18(25)15-20(19)26/h10-11,14-16H,6-9,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132893 (CHEMBL115759 | Dibutyl-[3-(2,4-dichloro-phenyl)-5-...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(n[nH]c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H26Cl2N4/c1-4-6-10-27(11-7-5-2)18-12-14(3)24-21-19(25-26-20(18)21)16-9-8-15(22)13-17(16)23/h8-9,12-13H,4-7,10-11H2,1-3H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132895 (CHEMBL115999 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(CC)nc12 |(8.04,5.06,;8.6,3.62,;7.62,2.42,;8.18,1,;9.7,.75,;10.68,1.95,;10.12,3.39,;12.19,1.72,;7.2,-.22,;7.78,-1.64,;6.81,-2.85,;7.37,-4.28,;5.29,-2.62,;4.73,-1.18,;3.28,-.64,;2.04,-1.54,;2.2,-3.07,;.96,-3.98,;-.46,-3.35,;-1.71,-4.26,;-.62,-1.82,;.64,-.91,;.48,.63,;3.35,.88,;2.15,1.84,;2.38,3.36,;4.84,1.3,;5.68,.02,)| Show InChI InChI=1S/C22H26Cl2N4/c1-4-10-27(13-15-6-7-15)19-11-14(3)25-21-20(19)26-28(5-2)22(21)17-9-8-16(23)12-18(17)24/h8-9,11-12,15H,4-7,10,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132911 (CHEMBL115818 | Dibutyl-[3-(2-chloro-4-methyl-pheny...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(-c3ccc(C)cc3Cl)n(CC)nc12 |(9.84,5.74,;8.86,4.52,;9.42,3.1,;8.46,1.89,;9.02,.46,;10.54,.23,;11.1,-1.22,;12.62,-1.46,;13.58,-.26,;8.04,-.75,;8.61,-2.18,;7.65,-3.37,;8.21,-4.82,;6.12,-3.14,;5.56,-1.71,;4.12,-1.17,;2.88,-2.06,;3.05,-3.61,;1.78,-4.52,;.38,-3.89,;-.86,-4.79,;.22,-2.36,;1.47,-1.43,;1.31,.09,;4.19,.35,;2.97,1.31,;3.21,2.84,;5.66,.76,;6.52,-.51,)| Show InChI InChI=1S/C24H33ClN4/c1-6-9-13-28(14-10-7-2)21-16-18(5)26-23-22(21)27-29(8-3)24(23)19-12-11-17(4)15-20(19)25/h11-12,15-16H,6-10,13-14H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132886 (Butyl-[3-(2,4-dichloro-phenyl)-5-methyl-1H-pyrazol...) Show SMILES CCCCN(CC)c1cc(C)nc2c(n[nH]c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4/c1-4-6-9-25(5-2)16-10-12(3)22-19-17(23-24-18(16)19)14-8-7-13(20)11-15(14)21/h7-8,10-11H,4-6,9H2,1-3H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132884 (CHEMBL116010 | Dibutyl-[3-(2,4-dichloro-phenyl)-5-...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(CCC)nc12 |(9.01,4.85,;8.05,3.64,;8.61,2.22,;7.64,1.02,;8.19,-.4,;9.72,-.64,;10.68,.56,;12.19,.33,;13.16,1.53,;7.23,-1.6,;7.8,-3.03,;6.84,-4.22,;7.4,-5.66,;5.31,-3.98,;4.75,-2.57,;3.33,-2.02,;2.09,-2.91,;2.26,-4.45,;1.01,-5.36,;-.4,-4.73,;-1.64,-5.64,;-.56,-3.21,;.68,-2.29,;.53,-.75,;3.4,-.51,;2.19,.44,;2.43,1.97,;1.22,2.92,;4.87,-.1,;5.71,-1.37,)| Show InChI InChI=1S/C24H32Cl2N4/c1-5-8-13-29(14-9-6-2)21-15-17(4)27-23-22(21)28-30(12-7-3)24(23)19-11-10-18(25)16-20(19)26/h10-11,15-16H,5-9,12-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132903 (CHEMBL116011 | Dibutyl-[3-(2-chloro-4-methoxy-phen...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(-c3ccc(OC)cc3Cl)n(C)nc12 |(16.56,-7.58,;16.02,-6.13,;14.5,-5.9,;13.94,-4.47,;12.42,-4.22,;11.85,-2.79,;12.82,-1.59,;12.26,-.15,;10.74,.09,;11.44,-5.43,;12,-6.86,;11.04,-8.07,;11.61,-9.5,;9.52,-7.83,;8.96,-6.39,;7.51,-5.85,;6.27,-6.76,;6.44,-8.28,;5.18,-9.2,;3.77,-8.57,;2.53,-9.48,;2.69,-11.01,;3.61,-7.04,;4.86,-6.13,;4.68,-4.59,;7.58,-4.33,;6.37,-3.37,;9.06,-3.91,;9.91,-5.2,)| Show InChI InChI=1S/C23H31ClN4O/c1-6-8-12-28(13-9-7-2)20-14-16(3)25-22-21(20)26-27(4)23(22)18-11-10-17(29-5)15-19(18)24/h10-11,14-15H,6-9,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132897 (Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyr...) Show SMILES CCCCN(CCc1ccc(OC)cc1)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 |(12.2,6.71,;11.25,5.52,;11.81,4.07,;10.83,2.88,;11.39,1.45,;12.9,1.2,;13.46,-.23,;14.98,-.47,;15.53,-1.9,;17.05,-2.15,;18.01,-.94,;19.53,-1.17,;20.5,.02,;17.45,.51,;15.93,.74,;10.42,.25,;10.99,-1.19,;10.03,-2.39,;10.59,-3.82,;8.5,-2.15,;7.94,-.72,;6.51,-.17,;5.27,-1.08,;5.43,-2.61,;4.18,-3.52,;2.77,-2.89,;1.52,-3.8,;2.61,-1.36,;3.86,-.45,;3.71,1.09,;6.58,1.34,;5.37,2.3,;8.05,1.75,;8.89,.48,)| Show InChI InChI=1S/C27H30Cl2N4O/c1-5-6-14-33(15-13-19-7-10-21(34-4)11-8-19)24-16-18(2)30-26-25(24)31-32(3)27(26)22-12-9-20(28)17-23(22)29/h7-12,16-17H,5-6,13-15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132909 (CHEMBL324495 | [3-(4-Chloro-phenyl)-2,5-dimethyl-2...) Show SMILES CCCN(CCC)c1cc(C)nc2c(-c3ccc(Cl)cc3)n(C)nc12 Show InChI InChI=1S/C20H25ClN4/c1-5-11-25(12-6-2)17-13-14(3)22-19-18(17)23-24(4)20(19)15-7-9-16(21)10-8-15/h7-10,13H,5-6,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132908 (CHEMBL325960 | Dibutyl-[3-(2,4-dichloro-phenyl)-5-...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(CCC)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H32Cl2N4/c1-5-8-13-29(14-9-6-2)21-15-17(4)27-23-22(28-30(12-7-3)24(21)23)19-11-10-18(25)16-20(19)26/h10-11,15-16H,5-9,12-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132891 ((2,5-Dimethyl-3-phenyl-2H-pyrazolo[4,3-b]pyridin-7...) Show SMILES CCCN(CCC)c1cc(C)nc2c(-c3ccccc3)n(C)nc12 Show InChI InChI=1S/C20H26N4/c1-5-12-24(13-6-2)17-14-15(3)21-19-18(17)22-23(4)20(19)16-10-8-7-9-11-16/h7-11,14H,5-6,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132901 (CHEMBL445075 | Cyclopropylmethyl-[3-(2,4-dichloro-...) Show SMILES CCCN(CC1CC1)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H24Cl2N4/c1-4-9-27(12-14-5-6-14)18-10-13(2)24-20-19(25-26(3)21(18)20)16-8-7-15(22)11-17(16)23/h7-8,10-11,14H,4-6,9,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP production				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132898 (CHEMBL115142 | Dibutyl-[3-(2,4-dichloro-phenyl)-1,...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H28Cl2N4/c1-5-7-11-28(12-8-6-2)19-13-15(3)25-21-20(26-27(4)22(19)21)17-10-9-16(23)14-18(17)24/h9-10,13-14H,5-8,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132892 (Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...) Show SMILES CCCCN(CC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H24Cl2N4/c1-5-7-10-26(6-2)17-11-13(3)23-19-18(24-25(4)20(17)19)15-9-8-14(21)12-16(15)22/h8-9,11-12H,5-7,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP production				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132899 (CHEMBL334039 | [3-(2,4-Dichloro-phenyl)-2,5-dimeth...) Show SMILES CCCN(CCC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 |(8.04,5.07,;8.6,3.62,;7.63,2.42,;8.19,1,;9.71,.75,;10.69,1.96,;12.21,1.72,;7.21,-.22,;7.79,-1.64,;6.81,-2.85,;7.37,-4.29,;5.29,-2.62,;4.73,-1.18,;3.28,-.64,;2.04,-1.54,;2.21,-3.07,;.96,-3.98,;-.46,-3.35,;-1.71,-4.26,;-.62,-1.82,;.64,-.91,;.48,.63,;3.35,.88,;2.15,1.84,;4.84,1.3,;5.69,.02,)| Show InChI InChI=1S/C20H24Cl2N4/c1-5-9-26(10-6-2)17-11-13(3)23-19-18(17)24-25(4)20(19)15-8-7-14(21)12-16(15)22/h7-8,11-12H,5-6,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP production				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair