Compile Data Set for Download or QSAR

Found 44 hits Enz. Inhib. hit(s) with all data for entry = 50036695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50018796 (2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...) Show SMILES COC([O-])=C1C(C(C(=[OH+])OC)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |w:2.2,c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-6-5-7-12(8-11)19(22)23/h5-8,15,20H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O |c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,13,15H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072809 (4-[2-(4-Cyano-furazan-3-ylmethoxy)-phenyl]-2,6-dim...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1OCc1nonc1C#N |c:13,t:10| Show InChI InChI=1S/C21H20N4O6/c1-11-17(20(26)28-3)19(18(12(2)23-11)21(27)29-4)13-7-5-6-8-16(13)30-10-15-14(9-22)24-31-25-15/h5-8,17,19H,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072811 (2,6-Dimethyl-4-[2-(4-methyl-5-oxy-furazan-3-ylmeth...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1no[n+]([O-])c1C)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H23N3O7/c1-11-17(20(25)28-4)19(18(12(2)22-11)21(26)29-5)14-8-6-7-9-16(14)30-10-15-13(3)24(27)31-23-15/h6-9,19H,10H2,1-5H3,(H,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072818 (4-[2-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1no[n+]([O-])c1C#N)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-7-5-6-8-16(13)31-10-14-15(9-22)25(28)32-24-14/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072803 (2,6-Dimethyl-4-[2-(4-methyl-furazan-3-ylmethoxy)-p...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1OCc1nonc1C |c:13,t:10| Show InChI InChI=1S/C21H23N3O6/c1-11-15(24-30-23-11)10-29-16-9-7-6-8-14(16)19-17(20(25)27-4)12(2)22-13(3)18(19)21(26)28-5/h6-9,17,19H,10H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072814 (4-[2-(4-Cyano-2-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1c(no[n+]1[O-])C#N)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-7-5-6-8-16(13)31-10-15-14(9-22)24-32-25(15)28/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072810 (2,6-Dimethyl-4-[2-(4-methyl-2-oxy-furazan-3-ylmeth...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1c(C)no[n+]1[O-])C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H23N3O7/c1-11-15(24(27)31-23-11)10-30-16-9-7-6-8-14(16)19-17(20(25)28-4)12(2)22-13(3)18(19)21(26)29-5/h6-9,19H,10H2,1-5H3,(H,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072816 (2,6-Dimethyl-4-[2-(2-nitrooxy-ethoxy)-phenyl]-1,4-...) Show SMILES COC([O-])=C1C(C(C(=[OH+])OC)=C(C)N=C1C)c1ccccc1OCCO[N+]([O-])=O |w:2.2,c:13,t:10| Show InChI InChI=1S/C19H22N2O8/c1-11-15(18(22)26-3)17(16(12(2)20-11)19(23)27-4)13-7-5-6-8-14(13)28-9-10-29-21(24)25/h5-8,17,22H,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072804 (4-[3-(4-Cyano-2-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2c(no[n+]2[O-])C#N)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-6-5-7-14(8-13)31-10-16-15(9-22)24-32-25(16)28/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072817 (4-[3-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C#N)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-6-5-7-14(8-13)31-10-15-16(9-22)25(28)32-24-15/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072806 (4-[3-(4-Cyano-furazan-3-ylmethoxy)-phenyl]-2,6-dim...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C#N)c1 |c:13,t:10| Show InChI InChI=1S/C21H20N4O6/c1-11-17(20(26)28-3)19(18(12(2)23-11)21(27)29-4)13-6-5-7-14(8-13)30-10-16-15(9-22)24-31-25-16/h5-8,17,19H,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072813 (2,6-Dimethyl-4-[3-(4-methyl-2-oxy-furazan-3-ylmeth...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2c(C)no[n+]2[O-])c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H23N3O7/c1-11-16(24(27)31-23-11)10-30-15-8-6-7-14(9-15)19-17(20(25)28-4)12(2)22-13(3)18(19)21(26)29-5/h6-9,19H,10H2,1-5H3,(H,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072812 (2,6-Dimethyl-4-[3-(4-methyl-furazan-3-ylmethoxy)-p...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C)c1 |c:13,t:10| Show InChI InChI=1S/C21H23N3O6/c1-11-16(24-30-23-11)10-29-15-8-6-7-14(9-15)19-17(20(25)27-4)12(2)22-13(3)18(19)21(26)28-5/h6-9,17,19H,10H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072807 (4-[2-(4-Carbamoyl-2-oxy-furazan-3-ylmethoxy)-pheny...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1c(no[n+]1[O-])C(N)=O)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H22N4O8/c1-10-15(20(27)30-3)17(16(11(2)23-10)21(28)31-4)12-7-5-6-8-14(12)32-9-13-18(19(22)26)24-33-25(13)29/h5-8,17H,9H2,1-4H3,(H3,22,23,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072800 (2,6-Dimethyl-4-[3-(4-methyl-5-oxy-furazan-3-ylmeth...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H23N3O7/c1-11-17(20(25)28-4)19(18(12(2)22-11)21(26)29-5)14-7-6-8-15(9-14)30-10-16-13(3)24(27)31-23-16/h6-9,19H,10H2,1-5H3,(H,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072801 (4-[2-(4-Carbamoyl-furazan-3-ylmethoxy)-phenyl]-2,6...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1OCc1nonc1C(N)=O |c:13,t:10| Show InChI InChI=1S/C21H22N4O7/c1-10-15(20(27)29-3)17(16(11(2)23-10)21(28)30-4)12-7-5-6-8-14(12)31-9-13-18(19(22)26)25-32-24-13/h5-8,15,17H,9H2,1-4H3,(H2,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072802 (2,6-Dimethyl-4-[3-(2-nitrooxy-ethoxy)-phenyl]-1,4-...) Show SMILES COC([O-])=C1C(C(C(=[OH+])OC)=C(C)N=C1C)c1cccc(OCCO[N+]([O-])=O)c1 |w:2.2,c:13,t:10| Show InChI InChI=1S/C19H22N2O8/c1-11-15(18(22)26-3)17(16(12(2)20-11)19(23)27-4)13-6-5-7-14(10-13)28-8-9-29-21(24)25/h5-7,10,17,22H,8-9H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072815 (4-[2-(4-Carbamoyl-5-oxy-furazan-3-ylmethoxy)-pheny...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1no[n+]([O-])c1C(N)=O)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H22N4O8/c1-10-15(20(27)30-3)17(16(11(2)23-10)21(28)31-4)12-7-5-6-8-14(12)32-9-13-18(19(22)26)25(29)33-24-13/h5-8,17H,9H2,1-4H3,(H3,22,23,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072808 (4-[3-(4-Carbamoyl-5-oxy-furazan-3-ylmethoxy)-pheny...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C(N)=O)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H22N4O8/c1-10-15(20(27)30-3)17(16(11(2)23-10)21(28)31-4)12-6-5-7-13(8-12)32-9-14-18(19(22)26)25(29)33-24-14/h5-8,17H,9H2,1-4H3,(H3,22,23,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072819 (4-[3-(4-Carbamoyl-2-oxy-furazan-3-ylmethoxy)-pheny...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2c(no[n+]2[O-])C(N)=O)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H22N4O8/c1-10-15(20(27)30-3)17(16(11(2)23-10)21(28)31-4)12-6-5-7-13(8-12)32-9-14-18(19(22)26)24-33-25(14)29/h5-8,17H,9H2,1-4H3,(H3,22,23,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072805 (4-[3-(4-Carbamoyl-furazan-3-ylmethoxy)-phenyl]-2,6...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C(N)=O)c1 |c:13,t:10| Show InChI InChI=1S/C21H22N4O7/c1-10-15(20(27)29-3)17(16(11(2)23-10)21(28)30-4)12-6-5-7-13(8-12)31-9-14-18(19(22)26)25-32-24-14/h5-8,15,17H,9H2,1-4H3,(H2,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50018796 (2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...) Show SMILES COC([O-])=C1C(C(C(=[OH+])OC)=C(C)N=C1C)c1cccc(c1)[N+]([O-])=O |w:2.2,c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-6-5-7-12(8-11)19(22)23/h5-8,15,20H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O |c:13,t:10| Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,13,15H,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072809 (4-[2-(4-Cyano-furazan-3-ylmethoxy)-phenyl]-2,6-dim...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1OCc1nonc1C#N |c:13,t:10| Show InChI InChI=1S/C21H20N4O6/c1-11-17(20(26)28-3)19(18(12(2)23-11)21(27)29-4)13-7-5-6-8-16(13)30-10-15-14(9-22)24-31-25-15/h5-8,17,19H,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072818 (4-[2-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1no[n+]([O-])c1C#N)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-7-5-6-8-16(13)31-10-14-15(9-22)25(28)32-24-14/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072811 (2,6-Dimethyl-4-[2-(4-methyl-5-oxy-furazan-3-ylmeth...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1no[n+]([O-])c1C)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H23N3O7/c1-11-17(20(25)28-4)19(18(12(2)22-11)21(26)29-5)14-8-6-7-9-16(14)30-10-15-13(3)24(27)31-23-15/h6-9,19H,10H2,1-5H3,(H,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072803 (2,6-Dimethyl-4-[2-(4-methyl-furazan-3-ylmethoxy)-p...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1OCc1nonc1C |c:13,t:10| Show InChI InChI=1S/C21H23N3O6/c1-11-15(24-30-23-11)10-29-16-9-7-6-8-14(16)19-17(20(25)27-4)12(2)22-13(3)18(19)21(26)28-5/h6-9,17,19H,10H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072814 (4-[2-(4-Cyano-2-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1c(no[n+]1[O-])C#N)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-7-5-6-8-16(13)31-10-15-14(9-22)24-32-25(15)28/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072810 (2,6-Dimethyl-4-[2-(4-methyl-2-oxy-furazan-3-ylmeth...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1c(C)no[n+]1[O-])C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H23N3O7/c1-11-15(24(27)31-23-11)10-30-16-9-7-6-8-14(16)19-17(20(25)28-4)12(2)22-13(3)18(19)21(26)29-5/h6-9,19H,10H2,1-5H3,(H,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072816 (2,6-Dimethyl-4-[2-(2-nitrooxy-ethoxy)-phenyl]-1,4-...) Show SMILES COC([O-])=C1C(C(C(=[OH+])OC)=C(C)N=C1C)c1ccccc1OCCO[N+]([O-])=O |w:2.2,c:13,t:10| Show InChI InChI=1S/C19H22N2O8/c1-11-15(18(22)26-3)17(16(12(2)20-11)19(23)27-4)13-7-5-6-8-14(13)28-9-10-29-21(24)25/h5-8,17,22H,9-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072817 (4-[3-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C#N)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-6-5-7-14(8-13)31-10-15-16(9-22)25(28)32-24-15/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072804 (4-[3-(4-Cyano-2-oxy-furazan-3-ylmethoxy)-phenyl]-2...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2c(no[n+]2[O-])C#N)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H20N4O7/c1-11-17(20(26)29-3)19(18(12(2)23-11)21(27)30-4)13-6-5-7-14(8-13)31-10-16-15(9-22)24-32-25(16)28/h5-8,19H,10H2,1-4H3,(H,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072806 (4-[3-(4-Cyano-furazan-3-ylmethoxy)-phenyl]-2,6-dim...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C#N)c1 |c:13,t:10| Show InChI InChI=1S/C21H20N4O6/c1-11-17(20(26)28-3)19(18(12(2)23-11)21(27)29-4)13-6-5-7-14(8-13)30-10-16-15(9-22)24-31-25-16/h5-8,17,19H,10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072813 (2,6-Dimethyl-4-[3-(4-methyl-2-oxy-furazan-3-ylmeth...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2c(C)no[n+]2[O-])c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H23N3O7/c1-11-16(24(27)31-23-11)10-30-15-8-6-7-14(9-15)19-17(20(25)28-4)12(2)22-13(3)18(19)21(26)29-5/h6-9,19H,10H2,1-5H3,(H,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072812 (2,6-Dimethyl-4-[3-(4-methyl-furazan-3-ylmethoxy)-p...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C)c1 |c:13,t:10| Show InChI InChI=1S/C21H23N3O6/c1-11-16(24-30-23-11)10-29-15-8-6-7-14(9-15)19-17(20(25)27-4)12(2)22-13(3)18(19)21(26)28-5/h6-9,17,19H,10H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072807 (4-[2-(4-Carbamoyl-2-oxy-furazan-3-ylmethoxy)-pheny...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1c(no[n+]1[O-])C(N)=O)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H22N4O8/c1-10-15(20(27)30-3)17(16(11(2)23-10)21(28)31-4)12-7-5-6-8-14(12)32-9-13-18(19(22)26)24-33-25(13)29/h5-8,17H,9H2,1-4H3,(H3,22,23,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072800 (2,6-Dimethyl-4-[3-(4-methyl-5-oxy-furazan-3-ylmeth...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H23N3O7/c1-11-17(20(25)28-4)19(18(12(2)22-11)21(26)29-5)14-7-6-8-15(9-14)30-10-16-13(3)24(27)31-23-16/h6-9,19H,10H2,1-5H3,(H,22,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072801 (4-[2-(4-Carbamoyl-furazan-3-ylmethoxy)-phenyl]-2,6...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1OCc1nonc1C(N)=O |c:13,t:10| Show InChI InChI=1S/C21H22N4O7/c1-10-15(20(27)29-3)17(16(11(2)23-10)21(28)30-4)12-7-5-6-8-14(12)31-9-13-18(19(22)26)25-32-24-13/h5-8,15,17H,9H2,1-4H3,(H2,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072802 (2,6-Dimethyl-4-[3-(2-nitrooxy-ethoxy)-phenyl]-1,4-...) Show SMILES COC([O-])=C1C(C(C(=[OH+])OC)=C(C)N=C1C)c1cccc(OCCO[N+]([O-])=O)c1 |w:2.2,c:13,t:10| Show InChI InChI=1S/C19H22N2O8/c1-11-15(18(22)26-3)17(16(12(2)20-11)19(23)27-4)13-6-5-7-14(10-13)28-8-9-29-21(24)25/h5-7,10,17,22H,8-9H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072815 (4-[2-(4-Carbamoyl-5-oxy-furazan-3-ylmethoxy)-pheny...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1ccccc1OCc1no[n+]([O-])c1C(N)=O)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H22N4O8/c1-10-15(20(27)30-3)17(16(11(2)23-10)21(28)31-4)12-7-5-6-8-14(12)32-9-13-18(19(22)26)25(29)33-24-13/h5-8,17H,9H2,1-4H3,(H3,22,23,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072808 (4-[3-(4-Carbamoyl-5-oxy-furazan-3-ylmethoxy)-pheny...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2no[n+]([O-])c2C(N)=O)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H22N4O8/c1-10-15(20(27)30-3)17(16(11(2)23-10)21(28)31-4)12-6-5-7-13(8-12)32-9-14-18(19(22)26)25(29)33-24-14/h5-8,17H,9H2,1-4H3,(H3,22,23,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072819 (4-[3-(4-Carbamoyl-2-oxy-furazan-3-ylmethoxy)-pheny...) Show SMILES COC(=O)C1=C(C)[N-]C(C)=C(C1c1cccc(OCc2c(no[n+]2[O-])C(N)=O)c1)C(=[OH+])OC |c:4,9| Show InChI InChI=1S/C21H22N4O8/c1-10-15(20(27)30-3)17(16(11(2)23-10)21(28)31-4)12-6-5-7-13(8-12)32-9-14-18(19(22)26)24-33-25(14)29/h5-8,17H,9H2,1-4H3,(H3,22,23,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus)	BDBM50072805 (4-[3-(4-Carbamoyl-furazan-3-ylmethoxy)-phenyl]-2,6...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(OCc2nonc2C(N)=O)c1 |c:13,t:10| Show InChI InChI=1S/C21H22N4O7/c1-10-15(20(27)29-3)17(16(11(2)23-10)21(28)30-4)12-6-5-7-13(8-12)31-9-14-18(19(22)26)25-32-24-14/h5-8,15,17H,9H2,1-4H3,(H2,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Torino Curated by ChEMBL					Assay Description Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.				J Med Chem 41: 5393-401 (1999) Article DOI: 10.1021/jm9803267 BindingDB Entry DOI: 10.7270/Q2WM1F30
					More data for this Ligand-Target Pair