Compile Data Set for Download or QSAR

Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50007588   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064981 (CHEMBL77405 | N-(1-Benzyl-piperidin-4-yl)-2-(3-bro...) Show SMILES Brc1cccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C20H23BrN2O/c21-18-8-4-7-17(13-18)14-20(24)22-19-9-11-23(12-10-19)15-16-5-2-1-3-6-16/h1-8,13,19H,9-12,14-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064959 (CHEMBL76864 | N-(1-Benzyl-piperidin-4-yl)-2-(3-chl...) Show SMILES Clc1cccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C20H23ClN2O/c21-18-8-4-7-17(13-18)14-20(24)22-19-9-11-23(12-10-19)15-16-5-2-1-3-6-16/h1-8,13,19H,9-12,14-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064962 (CHEMBL306768 | N-(1-Benzyl-piperidin-4-yl)-2-(3-fl...) Show SMILES Fc1cccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C20H23FN2O/c21-18-8-4-7-17(13-18)14-20(24)22-19-9-11-23(12-10-19)15-16-5-2-1-3-6-16/h1-8,13,19H,9-12,14-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Compound tested for binding affinity towards sigma 1 receptor in quinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand.				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064967 (CHEMBL431775 | N-(1-Benzyl-piperidin-4-yl)-2-(2-br...) Show SMILES Brc1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H23BrN2O/c21-19-9-5-4-8-17(19)14-20(24)22-18-10-12-23(13-11-18)15-16-6-2-1-3-7-16/h1-9,18H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064969 (CHEMBL76564 | N-(1-Benzyl-piperidin-4-yl)-2-(2-chl...) Show SMILES Clc1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H23ClN2O/c21-19-9-5-4-8-17(19)14-20(24)22-18-10-12-23(13-11-18)15-16-6-2-1-3-7-16/h1-9,18H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064955 (CHEMBL308818 | N-(1-Benzyl-piperidin-4-yl)-2-(3,4-...) Show SMILES Fc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1F Show InChI InChI=1S/C20H22F2N2O/c21-18-7-6-16(12-19(18)22)13-20(25)23-17-8-10-24(11-9-17)14-15-4-2-1-3-5-15/h1-7,12,17H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064979 (CHEMBL310499 | N-(1-Benzyl-piperidin-4-yl)-2-(4-fl...) Show SMILES Fc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H23FN2O/c21-18-8-6-16(7-9-18)14-20(24)22-19-10-12-23(13-11-19)15-17-4-2-1-3-5-17/h1-9,19H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064957 (CHEMBL76806 | N-(1-Benzyl-piperidin-4-yl)-2-(2-flu...) Show SMILES Fc1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H23FN2O/c21-19-9-5-4-8-17(19)14-20(24)22-18-10-12-23(13-11-18)15-16-6-2-1-3-7-16/h1-9,18H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064954 (CHEMBL76547 | N-(1-Benzyl-piperidin-4-yl)-2-(2,4-d...) Show SMILES Fc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c(F)c1 Show InChI InChI=1S/C20H22F2N2O/c21-17-7-6-16(19(22)13-17)12-20(25)23-18-8-10-24(11-9-18)14-15-4-2-1-3-5-15/h1-7,13,18H,8-12,14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064947 (CHEMBL76895 | N-(1-Benzyl-piperidin-4-yl)-2-phenyl...) Show SMILES O=C(Cc1ccccc1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O/c23-20(15-17-7-3-1-4-8-17)21-19-11-13-22(14-12-19)16-18-9-5-2-6-10-18/h1-10,19H,11-16H2,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064961 (CHEMBL77953 | N-(1-Benzyl-piperidin-4-yl)-2-(3-tri...) Show SMILES FC(F)(F)c1cccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C21H23F3N2O/c22-21(23,24)18-8-4-7-17(13-18)14-20(27)25-19-9-11-26(12-10-19)15-16-5-2-1-3-6-16/h1-8,13,19H,9-12,14-15H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064982 (CHEMBL77285 | N-(1-Benzyl-piperidin-4-yl)-2-(4-bro...) Show SMILES Brc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H23BrN2O/c21-18-8-6-16(7-9-18)14-20(24)22-19-10-12-23(13-11-19)15-17-4-2-1-3-5-17/h1-9,19H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064974 (CHEMBL77289 | N-(1-Benzyl-piperidin-4-yl)-2-(2,5-d...) Show SMILES Fc1ccc(F)c(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C20H22F2N2O/c21-17-6-7-19(22)16(12-17)13-20(25)23-18-8-10-24(11-9-18)14-15-4-2-1-3-5-15/h1-7,12,18H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064972 (CHEMBL311622 | N-(1-Benzyl-piperidin-4-yl)-2-(3-ni...) Show SMILES [O-][N+](=O)c1cccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C20H23N3O3/c24-20(14-17-7-4-8-19(13-17)23(25)26)21-18-9-11-22(12-10-18)15-16-5-2-1-3-6-16/h1-8,13,18H,9-12,14-15H2,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064977 (CHEMBL77286 | N-(1-Benzyl-piperidin-4-yl)-2-(3,4-d...) Show SMILES Clc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1Cl Show InChI InChI=1S/C20H22Cl2N2O/c21-18-7-6-16(12-19(18)22)13-20(25)23-17-8-10-24(11-9-17)14-15-4-2-1-3-5-15/h1-7,12,17H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064978 (CHEMBL78059 | N-(1-Benzyl-piperidin-4-yl)-2-(2,6-d...) Show SMILES Fc1cccc(F)c1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H22F2N2O/c21-18-7-4-8-19(22)17(18)13-20(25)23-16-9-11-24(12-10-16)14-15-5-2-1-3-6-15/h1-8,16H,9-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064944 (CHEMBL413057 | N-(1-Benzyl-piperidin-4-yl)-2-(4-ch...) Show SMILES Clc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H23ClN2O/c21-18-8-6-16(7-9-18)14-20(24)22-19-10-12-23(13-11-19)15-17-4-2-1-3-5-17/h1-9,19H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064976 (CHEMBL77352 | N-(1-Benzyl-piperidin-4-yl)-2-(2,6-d...) Show SMILES Clc1cccc(Cl)c1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H22Cl2N2O/c21-18-7-4-8-19(22)17(18)13-20(25)23-16-9-11-24(12-10-16)14-15-5-2-1-3-6-15/h1-8,16H,9-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064966 (2-Benzo[1,3]dioxol-5-yl-N-(1-benzyl-piperidin-4-yl...) Show SMILES O=C(Cc1ccc2OCOc2c1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H24N2O3/c24-21(13-17-6-7-19-20(12-17)26-15-25-19)22-18-8-10-23(11-9-18)14-16-4-2-1-3-5-16/h1-7,12,18H,8-11,13-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064950 (CHEMBL312254 | N-(1-Benzyl-piperidin-4-yl)-2-(3,5-...) Show SMILES Fc1cc(F)cc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C20H22F2N2O/c21-17-10-16(11-18(22)13-17)12-20(25)23-19-6-8-24(9-7-19)14-15-4-2-1-3-5-15/h1-5,10-11,13,19H,6-9,12,14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064971 (CHEMBL306955 | N-(1-Benzyl-piperidin-4-yl)-2-(2-tr...) Show SMILES FC(F)(F)c1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H23F3N2O/c22-21(23,24)19-9-5-4-8-17(19)14-20(27)25-18-10-12-26(13-11-18)15-16-6-2-1-3-7-16/h1-9,18H,10-15H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064953 (CHEMBL262760 | N-(1-Benzyl-piperidin-4-yl)-2-(2,4-...) Show SMILES Clc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c(Cl)c1 Show InChI InChI=1S/C20H22Cl2N2O/c21-17-7-6-16(19(22)13-17)12-20(25)23-18-8-10-24(11-9-18)14-15-4-2-1-3-5-15/h1-7,13,18H,8-12,14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064965 (CHEMBL77773 | N-(1-Benzyl-piperidin-4-yl)-2-(4-tri...) Show SMILES FC(F)(F)c1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C21H23F3N2O/c22-21(23,24)18-8-6-16(7-9-18)14-20(27)25-19-10-12-26(13-11-19)15-17-4-2-1-3-5-17/h1-9,19H,10-15H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064975 (CHEMBL312692 | N-(1-Benzyl-piperidin-4-yl)-2-(3-me...) Show SMILES COc1cccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C21H26N2O2/c1-25-20-9-5-8-18(14-20)15-21(24)22-19-10-12-23(13-11-19)16-17-6-3-2-4-7-17/h2-9,14,19H,10-13,15-16H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064970 (CHEMBL74665 | N-(1-Benzyl-piperidin-4-yl)-2-(2,4-d...) Show SMILES [O-][N+](=O)c1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c(c1)[N+]([O-])=O Show InChI InChI=1S/C20H22N4O5/c25-20(12-16-6-7-18(23(26)27)13-19(16)24(28)29)21-17-8-10-22(11-9-17)14-15-4-2-1-3-5-15/h1-7,13,17H,8-12,14H2,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064946 (4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydro...) Show SMILES OC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	14.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064986 (CHEMBL307253 | N-(1-Benzyl-piperidin-4-yl)-2-(4-ni...) Show SMILES [O-][N+](=O)c1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H23N3O3/c24-20(14-16-6-8-19(9-7-16)23(25)26)21-18-10-12-22(13-11-18)15-17-4-2-1-3-5-17/h1-9,18H,10-15H2,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064963 (CHEMBL311579 | N-(1-Benzyl-piperidin-4-yl)-2-(2-hy...) Show SMILES Oc1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O2/c23-19-9-5-4-8-17(19)14-20(24)21-18-10-12-22(13-11-18)15-16-6-2-1-3-7-16/h1-9,18,23H,10-15H2,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064968 (CHEMBL75810 | N-(1-Benzyl-piperidin-4-yl)-2-(3-chl...) Show SMILES Oc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1Cl Show InChI InChI=1S/C20H23ClN2O2/c21-18-12-16(6-7-19(18)24)13-20(25)22-17-8-10-23(11-9-17)14-15-4-2-1-3-5-15/h1-7,12,17,24H,8-11,13-14H2,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064987 (CHEMBL305728 | N-(1-Benzyl-piperidin-4-yl)-2-(2-ni...) Show SMILES [O-][N+](=O)c1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H23N3O3/c24-20(14-17-8-4-5-9-19(17)23(25)26)21-18-10-12-22(13-11-18)15-16-6-2-1-3-7-16/h1-9,18H,10-15H2,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	26.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064983 (CHEMBL75816 | N-(1-Benzyl-piperidin-4-yl)-2-(4-met...) Show SMILES CSc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C21H26N2OS/c1-25-20-9-7-17(8-10-20)15-21(24)22-19-11-13-23(14-12-19)16-18-5-3-2-4-6-18/h2-10,19H,11-16H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064951 (1-(1-Benzyl-piperidin-4-yl)-3-(2,4-dimethoxy-pheny...) Show SMILES COc1ccc(NC(=O)NC2CCN(Cc3ccccc3)CC2)c(OC)c1 Show InChI InChI=1S/C21H27N3O3/c1-26-18-8-9-19(20(14-18)27-2)23-21(25)22-17-10-12-24(13-11-17)15-16-6-4-3-5-7-16/h3-9,14,17H,10-13,15H2,1-2H3,(H2,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	30.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064949 (CHEMBL312631 | N-(1-Benzyl-piperidin-4-yl)-2-(2-me...) Show SMILES COc1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H26N2O2/c1-25-20-10-6-5-9-18(20)15-21(24)22-19-11-13-23(14-12-19)16-17-7-3-2-4-8-17/h2-10,19H,11-16H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064964 (2-(1-Benzyl-piperidin-4-ylamino)-1-(2,3-dimethoxy-...) Show SMILES COc1cccc(C(O)CNC2CCN(Cc3ccccc3)CC2)c1OC Show InChI InChI=1S/C22H30N2O3/c1-26-21-10-6-9-19(22(21)27-2)20(25)15-23-18-11-13-24(14-12-18)16-17-7-4-3-5-8-17/h3-10,18,20,23,25H,11-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	32.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064980 (CHEMBL308097 | N-(1-Benzyl-piperidin-4-yl)-2-(2,5-...) Show SMILES COc1ccc(OC)c(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C22H28N2O3/c1-26-20-8-9-21(27-2)18(14-20)15-22(25)23-19-10-12-24(13-11-19)16-17-6-4-3-5-7-17/h3-9,14,19H,10-13,15-16H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064945 (1-(1-Benzyl-piperidin-4-yl)-3-(4-methylsulfanyl-ph...) Show SMILES CSc1ccc(NC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H25N3OS/c1-25-19-9-7-17(8-10-19)21-20(24)22-18-11-13-23(14-12-18)15-16-5-3-2-4-6-16/h2-10,18H,11-15H2,1H3,(H2,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064984 (CHEMBL308304 | N-(1-Benzyl-piperidin-4-yl)-2-(4-me...) Show SMILES COc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C21H26N2O2/c1-25-20-9-7-17(8-10-20)15-21(24)22-19-11-13-23(14-12-19)16-18-5-3-2-4-6-18/h2-10,19H,11-16H2,1H3,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	66.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064956 (CHEMBL80326 | N-(1-Benzyl-piperidin-4-yl)-2-(3,4,5...) Show SMILES COc1cc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc(OC)c1OC Show InChI InChI=1S/C23H30N2O4/c1-27-20-13-18(14-21(28-2)23(20)29-3)15-22(26)24-19-9-11-25(12-10-19)16-17-7-5-4-6-8-17/h4-8,13-14,19H,9-12,15-16H2,1-3H3,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064952 (CHEMBL419656 | N-(1-Benzyl-piperidin-4-yl)-2-(3-hy...) Show SMILES Oc1cccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C20H24N2O2/c23-19-8-4-7-17(13-19)14-20(24)21-18-9-11-22(12-10-18)15-16-5-2-1-3-6-16/h1-8,13,18,23H,9-12,14-15H2,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064985 (CHEMBL312576 | N-(1-Benzyl-piperidin-4-yl)-2-(3,5-...) Show SMILES COc1cc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc(OC)c1 Show InChI InChI=1S/C22H28N2O3/c1-26-20-12-18(13-21(15-20)27-2)14-22(25)23-19-8-10-24(11-9-19)16-17-6-4-3-5-7-17/h3-7,12-13,15,19H,8-11,14,16H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064948 (CHEMBL75864 | N-(1-Benzyl-piperidin-4-yl)-2-(4-hyd...) Show SMILES Oc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H24N2O2/c23-19-8-6-16(7-9-19)14-20(24)21-18-10-12-22(13-11-18)15-17-4-2-1-3-5-17/h1-9,18,23H,10-15H2,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	287	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064960 (CHEMBL76528 | N-(1-Benzyl-piperidin-4-yl)-2-(3,4-d...) Show SMILES COc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1OC Show InChI InChI=1S/C22H28N2O3/c1-26-20-9-8-18(14-21(20)27-2)15-22(25)23-19-10-12-24(13-11-19)16-17-6-4-3-5-7-17/h3-9,14,19H,10-13,15-16H2,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	352	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064973 (2-(4-Amino-phenyl)-N-(1-benzyl-piperidin-4-yl)-ace...) Show SMILES Nc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H25N3O/c21-18-8-6-16(7-9-18)14-20(24)22-19-10-12-23(13-11-19)15-17-4-2-1-3-5-17/h1-9,19H,10-15,21H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064958 (CHEMBL309228 | N-(1-Benzyl-piperidin-4-yl)-2-(3,4-...) Show SMILES Oc1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1O Show InChI InChI=1S/C20H24N2O3/c23-18-7-6-16(12-19(18)24)13-20(25)21-17-8-10-22(11-9-17)14-15-4-2-1-3-5-15/h1-7,12,17,23-24H,8-11,13-14H2,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Compound tested for binding affinity towards sigma 1 receptor in quinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand.				J Med Chem 41: 2361-70 (1998) Article DOI: 10.1021/jm980032l BindingDB Entry DOI: 10.7270/Q2RN36Z5
					More data for this Ligand-Target Pair