Compile Data Set for Download or QSAR

Found 15 hits Enz. Inhib. hit(s) with all data for entry = 50008759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076903 (3-(2-Bromo-4-isopropyl-phenyl)-7-(cyclopropylmethy...) Show SMILES CCCN(CC1CC1)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=O)sc12 |(16.46,-9.59,;15.12,-10.36,;15.13,-11.91,;13.8,-12.68,;12.46,-11.92,;12.46,-10.39,;13.22,-9.05,;11.69,-9.05,;13.8,-14.21,;12.48,-14.97,;12.48,-16.52,;11.14,-17.3,;13.8,-17.3,;15.15,-16.52,;16.62,-16.98,;17.1,-18.44,;16.08,-19.58,;16.55,-21.04,;18.06,-21.34,;19.08,-20.19,;18.59,-18.75,;19.67,-17.65,;18.54,-22.81,;17.52,-23.95,;20.06,-23.12,;17.52,-15.74,;19.05,-15.74,;16.6,-14.5,;15.13,-14.97,)| Show InChI InChI=1S/C22H27BrN4OS/c1-5-10-26(12-15-6-7-15)20-19-21(25-14(4)24-20)27(22(28)29-19)18-9-8-16(13(2)3)11-17(18)23/h8-9,11,13,15H,5-7,10,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076905 (3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-me...) Show SMILES CCN(CC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=S)sc12 |(12.56,-9.82,;12.57,-11.35,;13.88,-12.12,;15.23,-11.35,;15.23,-9.8,;13.91,-13.66,;12.57,-14.45,;12.57,-15.97,;11.25,-16.74,;13.91,-16.74,;15.25,-15.97,;16.7,-16.44,;17.18,-17.89,;16.16,-19.04,;16.64,-20.51,;18.17,-20.8,;19.19,-19.65,;18.69,-18.2,;19.78,-17.11,;18.65,-22.27,;17.62,-23.42,;20.15,-22.59,;17.62,-15.19,;19.16,-15.19,;16.7,-13.95,;15.23,-14.43,)| Show InChI InChI=1S/C19H23BrN4S2/c1-6-23(7-2)17-16-18(22-12(5)21-17)24(19(25)26-16)15-9-8-13(11(3)4)10-14(15)20/h8-11H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076902 (7-[Bis-(2-methoxy-ethyl)-amino]-5-methyl-3-(2,4,6-...) Show SMILES COCCN(CCOC)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=O)sc12 |(18.84,-10.28,;17.3,-10.28,;15.96,-11.05,;15.96,-12.59,;14.63,-13.38,;13.29,-12.61,;13.29,-11.07,;12.51,-9.75,;10.97,-9.73,;14.64,-14.92,;13.31,-15.69,;13.31,-17.23,;11.97,-18,;14.64,-18,;15.99,-17.23,;17.45,-17.69,;17.93,-19.15,;19.44,-19.45,;20.45,-18.3,;19.92,-20.9,;18.9,-22.07,;19.39,-23.53,;17.39,-21.76,;16.91,-20.29,;15.4,-19.97,;18.36,-16.44,;19.9,-16.44,;17.43,-15.19,;15.98,-15.69,)| Show InChI InChI=1S/C21H28N4O3S/c1-13-11-14(2)17(15(3)12-13)25-20-18(29-21(25)26)19(22-16(4)23-20)24(7-9-27-5)8-10-28-6/h11-12H,7-10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076899 (7-[Bis-(2-methoxy-ethyl)-amino]-3-(2-bromo-4-isopr...) Show SMILES COCCN(CCOC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=S)sc12 |(18.56,-10.19,;17.24,-9.42,;15.9,-10.19,;15.9,-11.74,;14.58,-12.51,;13.24,-11.74,;13.24,-10.22,;11.9,-9.45,;10.57,-10.22,;14.59,-14.04,;13.26,-14.83,;13.26,-16.37,;11.93,-17.14,;14.59,-17.14,;15.93,-16.35,;17.4,-16.83,;17.88,-18.27,;16.85,-19.43,;17.33,-20.89,;18.85,-21.19,;19.88,-20.04,;19.38,-18.59,;20.47,-17.49,;19.33,-22.66,;18.31,-23.81,;20.84,-22.97,;18.31,-15.57,;19.84,-15.57,;17.38,-14.33,;15.92,-14.81,)| Show InChI InChI=1S/C21H27BrN4O2S2/c1-13(2)15-6-7-17(16(22)12-15)26-20-18(30-21(26)29)19(23-14(3)24-20)25(8-10-27-4)9-11-28-5/h6-7,12-13H,8-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076906 (7-[Bis-(2-methoxy-ethyl)-amino]-5-methyl-3-(2,4,6-...) Show SMILES COCCN(CCOC)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=S)sc12 |(18.84,-10.28,;17.3,-10.28,;15.96,-11.05,;15.96,-12.59,;14.63,-13.38,;13.29,-12.61,;13.29,-11.07,;12.51,-9.75,;10.97,-9.73,;14.64,-14.92,;13.31,-15.69,;13.31,-17.23,;11.97,-18,;14.64,-18,;15.99,-17.23,;17.45,-17.69,;17.93,-19.15,;19.44,-19.45,;20.45,-18.3,;19.92,-20.9,;18.9,-22.07,;19.39,-23.53,;17.39,-21.76,;16.91,-20.29,;15.4,-19.97,;18.36,-16.44,;19.9,-16.44,;17.43,-15.19,;15.98,-15.69,)| Show InChI InChI=1S/C21H28N4O2S2/c1-13-11-14(2)17(15(3)12-13)25-20-18(29-21(25)28)19(22-16(4)23-20)24(7-9-26-5)8-10-27-6/h11-12H,7-10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076901 (7-Diethylamino-5-methyl-3-(2,4,6-trimethyl-phenyl)...) Show SMILES CCN(CC)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=S)sc12 |(15.45,-10.38,;15.46,-11.93,;14.11,-12.7,;12.79,-11.93,;12.79,-10.39,;14.11,-14.24,;12.8,-15.01,;12.8,-16.55,;11.45,-17.32,;14.11,-17.32,;15.46,-16.55,;16.93,-17.02,;17.41,-18.47,;18.92,-18.78,;19.93,-17.63,;19.4,-20.23,;18.37,-21.39,;18.88,-22.85,;16.87,-21.07,;16.39,-19.62,;14.88,-19.3,;17.83,-15.77,;19.37,-15.77,;16.92,-14.53,;15.46,-15.01,)| Show InChI InChI=1S/C19H24N4S2/c1-7-22(8-2)17-16-18(21-14(6)20-17)23(19(24)25-16)15-12(4)9-11(3)10-13(15)5/h9-10H,7-8H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076900 (3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-me...) Show SMILES CCN(CC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=O)sc12 |(12.56,-9.82,;12.57,-11.35,;13.88,-12.12,;15.23,-11.35,;15.23,-9.8,;13.91,-13.66,;12.57,-14.45,;12.57,-15.97,;11.25,-16.74,;13.91,-16.74,;15.25,-15.97,;16.7,-16.44,;17.18,-17.89,;16.16,-19.04,;16.64,-20.51,;18.17,-20.8,;19.19,-19.65,;18.69,-18.2,;19.78,-17.11,;18.65,-22.27,;17.62,-23.42,;20.15,-22.59,;17.62,-15.19,;19.16,-15.19,;16.7,-13.95,;15.23,-14.43,)| Show InChI InChI=1S/C19H23BrN4OS/c1-6-23(7-2)17-16-18(22-12(5)21-17)24(19(25)26-16)15-9-8-13(11(3)4)10-14(15)20/h8-11H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076893 (3-(2-Bromo-4-isopropyl-phenyl)-7-(cyclopropylmethy...) Show SMILES CCCN(CC1CC1)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=S)sc12 |(16.46,-9.59,;15.12,-10.36,;15.13,-11.91,;13.8,-12.68,;12.46,-11.92,;12.46,-10.39,;13.22,-9.05,;11.69,-9.05,;13.8,-14.21,;12.48,-14.99,;12.48,-16.52,;11.14,-17.3,;13.8,-17.3,;15.15,-16.52,;16.62,-16.98,;17.1,-18.44,;16.08,-19.58,;16.55,-21.04,;18.06,-21.34,;19.08,-20.19,;18.59,-18.75,;19.67,-17.65,;18.54,-22.81,;17.52,-23.95,;20.06,-23.12,;17.52,-15.74,;19.05,-15.73,;16.6,-14.5,;15.13,-14.97,)| Show InChI InChI=1S/C22H27BrN4S2/c1-5-10-26(12-15-6-7-15)20-19-21(25-14(4)24-20)27(22(28)29-19)18-9-8-16(13(2)3)11-17(18)23/h8-9,11,13,15H,5-7,10,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076897 (7-(Cyclopropylmethyl-propyl-amino)-5-methyl-3-(2,4...) Show SMILES CCCN(CC1CC1)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=S)sc12 |(16.68,-10.17,;15.34,-10.93,;15.36,-12.48,;14.02,-13.25,;12.68,-12.49,;12.68,-10.96,;13.43,-9.63,;11.91,-9.63,;14.02,-14.78,;12.7,-15.57,;12.7,-17.11,;11.37,-17.87,;14.02,-17.87,;15.36,-17.1,;16.82,-17.55,;17.32,-19.02,;18.81,-19.32,;19.81,-18.16,;19.3,-20.77,;18.27,-21.91,;18.76,-23.38,;16.76,-21.62,;16.28,-20.16,;14.78,-19.84,;17.73,-16.31,;19.27,-16.3,;16.82,-15.07,;15.36,-15.55,)| Show InChI InChI=1S/C22H28N4S2/c1-6-9-25(12-17-7-8-17)20-19-21(24-16(5)23-20)26(22(27)28-19)18-14(3)10-13(2)11-15(18)4/h10-11,17H,6-9,12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076894 (7-[Bis-(2-methoxy-ethyl)-amino]-3-(2-bromo-4-isopr...) Show SMILES COCCN(CCOC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=O)sc12 |(18.56,-10.19,;17.24,-9.42,;15.9,-10.19,;15.9,-11.74,;14.58,-12.51,;13.24,-11.74,;13.24,-10.22,;11.9,-9.45,;10.57,-10.22,;14.59,-14.04,;13.26,-14.83,;13.26,-16.37,;11.93,-17.14,;14.59,-17.14,;15.93,-16.35,;17.4,-16.83,;17.88,-18.27,;16.85,-19.43,;17.33,-20.89,;18.85,-21.19,;19.88,-20.04,;19.38,-18.59,;20.47,-17.49,;19.33,-22.66,;18.31,-23.81,;20.84,-22.97,;18.31,-15.57,;19.84,-15.57,;17.38,-14.33,;15.92,-14.81,)| Show InChI InChI=1S/C21H27BrN4O3S/c1-13(2)15-6-7-17(16(22)12-15)26-20-18(30-21(26)27)19(23-14(3)24-20)25(8-10-28-4)9-11-29-5/h6-7,12-13H,8-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076892 (7-Diethylamino-5-methyl-3-(2,4,6-trimethyl-phenyl)...) Show SMILES CCN(CC)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=O)sc12 |(15.45,-10.38,;15.46,-11.93,;14.11,-12.7,;12.79,-11.93,;12.79,-10.39,;14.11,-14.24,;12.8,-15.01,;12.8,-16.55,;11.45,-17.32,;14.11,-17.32,;15.46,-16.55,;16.93,-17.02,;17.41,-18.47,;18.92,-18.78,;19.93,-17.63,;19.4,-20.23,;18.37,-21.39,;18.88,-22.85,;16.87,-21.07,;16.39,-19.62,;14.88,-19.3,;17.83,-15.77,;19.37,-15.77,;16.92,-14.53,;15.46,-15.01,)| Show InChI InChI=1S/C19H24N4OS/c1-7-22(8-2)17-16-18(21-14(6)20-17)23(19(24)25-16)15-12(4)9-11(3)10-13(15)5/h9-10H,7-8H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076898 (7-(Cyclopropylmethyl-propyl-amino)-5-methyl-3-(2,4...) Show SMILES CCCN(CC1CC1)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=O)sc12 |(16.68,-10.17,;15.34,-10.93,;15.36,-12.48,;14.02,-13.25,;12.68,-12.49,;12.68,-10.96,;13.43,-9.63,;11.91,-9.63,;14.02,-14.78,;12.7,-15.57,;12.7,-17.11,;11.37,-17.87,;14.02,-17.87,;15.36,-17.1,;16.82,-17.55,;17.32,-19.02,;18.81,-19.32,;19.81,-18.16,;19.3,-20.77,;18.27,-21.91,;18.76,-23.38,;16.76,-21.62,;16.28,-20.16,;14.78,-19.84,;17.73,-16.31,;19.27,-16.3,;16.82,-15.07,;15.36,-15.55,)| Show InChI InChI=1S/C22H28N4OS/c1-6-9-25(12-17-7-8-17)20-19-21(24-16(5)23-20)26(22(27)28-19)18-14(3)10-13(2)11-15(18)4/h10-11,17H,6-9,12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076896 (3-(2-Bromo-4-isopropyl-phenyl)-7-(butyl-ethyl-amin...) Show SMILES CCCCN(CC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=S)sc12 |(11.23,-8.67,;11.25,-10.21,;12.58,-10.98,;12.58,-12.52,;13.93,-13.28,;15.26,-12.5,;15.24,-10.94,;13.93,-14.82,;12.6,-15.59,;12.6,-17.13,;11.26,-17.9,;13.93,-17.9,;15.27,-17.13,;16.75,-17.58,;17.23,-19.06,;16.2,-20.2,;16.68,-21.65,;18.19,-21.97,;19.22,-20.81,;18.72,-19.34,;19.81,-18.25,;18.67,-23.42,;17.65,-24.57,;20.18,-23.74,;17.65,-16.33,;19.17,-16.33,;16.72,-15.1,;15.27,-15.59,)| Show InChI InChI=1S/C21H27BrN4S2/c1-6-8-11-25(7-2)19-18-20(24-14(5)23-19)26(21(27)28-18)17-10-9-15(13(3)4)12-16(17)22/h9-10,12-13H,6-8,11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076904 (3-(2-Bromo-4-isopropyl-phenyl)-7-(di-sec-butyl-ami...) Show SMILES CCC(C)N(C(C)CC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=S)sc12 |(11.24,-9.46,;12.59,-10.23,;12.59,-11.75,;11.26,-12.52,;13.92,-12.52,;15.25,-11.75,;16.6,-12.52,;15.25,-10.21,;16.59,-9.43,;13.93,-14.06,;12.59,-14.83,;12.59,-16.39,;11.26,-17.16,;13.93,-17.16,;15.28,-16.37,;16.75,-16.85,;17.23,-18.3,;16.2,-19.45,;16.68,-20.92,;18.19,-21.22,;19.22,-20.06,;18.71,-18.62,;19.83,-17.52,;18.68,-22.69,;17.66,-23.84,;20.18,-23,;17.65,-15.6,;19.19,-15.6,;16.73,-14.35,;15.27,-14.83,)| Show InChI InChI=1S/C23H31BrN4S2/c1-8-14(5)27(15(6)9-2)21-20-22(26-16(7)25-21)28(23(29)30-20)19-11-10-17(13(3)4)12-18(19)24/h10-15H,8-9H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076895 (3-(2-Bromo-4-isopropyl-phenyl)-5-methyl-7-morpholi...) Show SMILES CC(C)c1ccc(c(Br)c1)-n1c2nc(C)nc(N3CCOCC3)c2sc1=S |(17.64,-23.83,;18.67,-22.68,;20.18,-22.98,;18.19,-21.21,;16.66,-20.89,;16.18,-19.45,;17.2,-18.29,;18.71,-18.6,;19.8,-17.51,;19.21,-20.06,;16.72,-16.84,;15.27,-16.37,;13.92,-17.14,;12.58,-16.37,;11.26,-17.14,;12.58,-14.83,;13.92,-14.06,;13.9,-12.52,;12.58,-11.75,;12.57,-10.21,;13.9,-9.44,;15.25,-10.2,;15.25,-11.75,;15.25,-14.83,;16.72,-14.35,;17.64,-15.59,;19.18,-15.59,)| Show InChI InChI=1S/C19H21BrN4OS2/c1-11(2)13-4-5-15(14(20)10-13)24-18-16(27-19(24)26)17(21-12(3)22-18)23-6-8-25-9-7-23/h4-5,10-11H,6-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair