Compile Data Set for Download or QSAR

Found 49 hits Enz. Inhib. hit(s) with all data for entry = 50011411   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50102780 (2-(2-Hydroxy-3-phenyl-phenyl)-1H-indole-5-carboxam...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O/c22-21(23)14-9-10-18-15(11-14)12-19(24-18)17-8-4-7-16(20(17)25)13-5-2-1-3-6-13/h1-12,24-25H,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50106240 (6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50106239 (6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1F)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16FN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50102780 (2-(2-Hydroxy-3-phenyl-phenyl)-1H-indole-5-carboxam...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O/c22-21(23)14-9-10-18-15(11-14)12-19(24-18)17-8-4-7-16(20(17)25)13-5-2-1-3-6-13/h1-12,24-25H,(H3,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human tissue plasminogen activator				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50102780 (2-(2-Hydroxy-3-phenyl-phenyl)-1H-indole-5-carboxam...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O/c22-21(23)14-9-10-18-15(11-14)12-19(24-18)17-8-4-7-16(20(17)25)13-5-2-1-3-6-13/h1-12,24-25H,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50102780 (2-(2-Hydroxy-3-phenyl-phenyl)-1H-indole-5-carboxam...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O/c22-21(23)14-9-10-18-15(11-14)12-19(24-18)17-8-4-7-16(20(17)25)13-5-2-1-3-6-13/h1-12,24-25H,(H3,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human plasmin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50106243 (2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...) Show SMILES Cc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C22H19N3O/c1-13-10-19-15(11-18(13)22(23)24)12-20(25-19)17-9-5-8-16(21(17)26)14-6-3-2-4-7-14/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106240 (6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human plasmin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50102780 (2-(2-Hydroxy-3-phenyl-phenyl)-1H-indole-5-carboxam...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O/c22-21(23)14-9-10-18-15(11-14)12-19(24-18)17-8-4-7-16(20(17)25)13-5-2-1-3-6-13/h1-12,24-25H,(H3,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human trypsin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50102780 (2-(2-Hydroxy-3-phenyl-phenyl)-1H-indole-5-carboxam...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O/c22-21(23)14-9-10-18-15(11-14)12-19(24-18)17-8-4-7-16(20(17)25)13-5-2-1-3-6-13/h1-12,24-25H,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human coagulation factor VII				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106243 (2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...) Show SMILES Cc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C22H19N3O/c1-13-10-19-15(11-18(13)22(23)24)12-20(25-19)17-9-5-8-16(21(17)26)14-6-3-2-4-7-14/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human plasmin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50106240 (6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human trypsin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50102780 (2-(2-Hydroxy-3-phenyl-phenyl)-1H-indole-5-carboxam...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O/c22-21(23)14-9-10-18-15(11-14)12-19(24-18)17-8-4-7-16(20(17)25)13-5-2-1-3-6-13/h1-12,24-25H,(H3,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human thrombin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106239 (6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1F)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16FN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human plasmin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50106241 (2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...) Show SMILES COc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(c1O)-c1ccccc1 Show InChI InChI=1S/C22H19N3O2/c1-27-20-12-18-14(10-17(20)22(23)24)11-19(25-18)16-9-5-8-15(21(16)26)13-6-3-2-4-7-13/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50106238 (4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-19-15(21(23)24)9-10-17-16(19)11-18(25-17)14-8-4-7-13(20(14)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50106239 (6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1F)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16FN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human coagulation factor VII				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50106239 (6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1F)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16FN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human trypsin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50106239 (6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1F)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16FN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50106243 (2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...) Show SMILES Cc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C22H19N3O/c1-13-10-19-15(11-18(13)22(23)24)12-20(25-19)17-9-5-8-16(21(17)26)14-6-3-2-4-7-14/h2-12,25-26H,1H3,(H3,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human trypsin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50106240 (6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human coagulation factor VII				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50106242 (6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1O)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O2/c22-21(23)16-9-13-10-18(24-17(13)11-19(16)25)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,24-26H,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human urokinase type plasminogen activator (microPa)				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106238 (4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-19-15(21(23)24)9-10-17-16(19)11-18(25-17)14-8-4-7-13(20(14)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human plasmin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106238 (4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-19-15(21(23)24)9-10-17-16(19)11-18(25-17)14-8-4-7-13(20(14)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human tissue plasminogen activator				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106239 (6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1F)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16FN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human tissue plasminogen activator				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106241 (2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...) Show SMILES COc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(c1O)-c1ccccc1 Show InChI InChI=1S/C22H19N3O2/c1-27-20-12-18-14(10-17(20)22(23)24)11-19(25-18)16-9-5-8-15(21(16)26)13-6-3-2-4-7-13/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human plasmin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50106238 (4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-19-15(21(23)24)9-10-17-16(19)11-18(25-17)14-8-4-7-13(20(14)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human trypsin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50106238 (4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-19-15(21(23)24)9-10-17-16(19)11-18(25-17)14-8-4-7-13(20(14)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50106238 (4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-19-15(21(23)24)9-10-17-16(19)11-18(25-17)14-8-4-7-13(20(14)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human coagulation factor VII				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50106243 (2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...) Show SMILES Cc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C22H19N3O/c1-13-10-19-15(11-18(13)22(23)24)12-20(25-19)17-9-5-8-16(21(17)26)14-6-3-2-4-7-14/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human coagulation factor VII				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50106239 (6-Fluoro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1F)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16FN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human thrombin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106240 (6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human tissue plasminogen activator				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50106241 (2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...) Show SMILES COc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(c1O)-c1ccccc1 Show InChI InChI=1S/C22H19N3O2/c1-27-20-12-18-14(10-17(20)22(23)24)11-19(25-18)16-9-5-8-15(21(16)26)13-6-3-2-4-7-13/h2-12,25-26H,1H3,(H3,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human trypsin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50106241 (2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...) Show SMILES COc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(c1O)-c1ccccc1 Show InChI InChI=1S/C22H19N3O2/c1-27-20-12-18-14(10-17(20)22(23)24)11-19(25-18)16-9-5-8-15(21(16)26)13-6-3-2-4-7-13/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human coagulation factor VII				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106241 (2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...) Show SMILES COc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(c1O)-c1ccccc1 Show InChI InChI=1S/C22H19N3O2/c1-27-20-12-18-14(10-17(20)22(23)24)11-19(25-18)16-9-5-8-15(21(16)26)13-6-3-2-4-7-13/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human tissue plasminogen activator				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106242 (6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1O)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O2/c22-21(23)16-9-13-10-18(24-17(13)11-19(16)25)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,24-26H,(H3,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human plasmin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50106240 (6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50106241 (2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...) Show SMILES COc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(c1O)-c1ccccc1 Show InChI InChI=1S/C22H19N3O2/c1-27-20-12-18-14(10-17(20)22(23)24)11-19(25-18)16-9-5-8-15(21(16)26)13-6-3-2-4-7-13/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106243 (2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...) Show SMILES Cc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C22H19N3O/c1-13-10-19-15(11-18(13)22(23)24)12-20(25-19)17-9-5-8-16(21(17)26)14-6-3-2-4-7-14/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human tissue plasminogen activator				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50106242 (6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1O)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O2/c22-21(23)16-9-13-10-18(24-17(13)11-19(16)25)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,24-26H,(H3,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human tissue plasminogen activator				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Serine protease 1/Trypsin-2 (Homo sapiens (Human))	BDBM50106242 (6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1O)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O2/c22-21(23)16-9-13-10-18(24-17(13)11-19(16)25)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,24-26H,(H3,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human trypsin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50106240 (6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-17-11-18-13(9-16(17)21(23)24)10-19(25-18)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human thrombin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50106238 (4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) Show SMILES NC(=N)c1ccc2[nH]c(cc2c1Cl)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H16ClN3O/c22-19-15(21(23)24)9-10-17-16(19)11-18(25-17)14-8-4-7-13(20(14)26)12-5-2-1-3-6-12/h1-11,25-26H,(H3,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human thrombin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50106241 (2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-...) Show SMILES COc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(c1O)-c1ccccc1 Show InChI InChI=1S/C22H19N3O2/c1-27-20-12-18-14(10-17(20)22(23)24)11-19(25-18)16-9-5-8-15(21(16)26)13-6-3-2-4-7-13/h2-12,25-26H,1H3,(H3,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human thrombin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50106242 (6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1O)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O2/c22-21(23)16-9-13-10-18(24-17(13)11-19(16)25)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,24-26H,(H3,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human thrombin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM50106242 (6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1O)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O2/c22-21(23)16-9-13-10-18(24-17(13)11-19(16)25)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,24-26H,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human coagulation factor VII				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50106242 (6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-...) Show SMILES NC(=N)c1cc2cc([nH]c2cc1O)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C21H17N3O2/c22-21(23)16-9-13-10-18(24-17(13)11-19(16)25)15-8-4-7-14(20(15)26)12-5-2-1-3-6-12/h1-11,24-26H,(H3,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50106243 (2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...) Show SMILES Cc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C22H19N3O/c1-13-10-19-15(11-18(13)22(23)24)12-20(25-19)17-9-5-8-16(21(17)26)14-6-3-2-4-7-14/h2-12,25-26H,1H3,(H3,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description The compound was tested for inhibition of human thrombin				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50106243 (2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-c...) Show SMILES Cc1cc2[nH]c(cc2cc1C(N)=N)-c1cccc(-c2ccccc2)c1O Show InChI InChI=1S/C22H19N3O/c1-13-10-19-15(11-18(13)22(23)24)12-20(25-19)17-9-5-8-16(21(17)26)14-6-3-2-4-7-14/h2-12,25-26H,1H3,(H3,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against human coagulation factor X				J Med Chem 44: 3856-71 (2001) BindingDB Entry DOI: 10.7270/Q22R3QXR
					More data for this Ligand-Target Pair