Compile Data Set for Download or QSAR

Found 46 hits Enz. Inhib. hit(s) with all data for entry = 50011499   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107225 (2-(3-Chloro-phenyl)-N-[1-(4-fluoro-benzyl)-piperid...) Show SMILES Fc1ccc(CN2CCC(CC2)NC(=O)Cc2cccc(Cl)c2)cc1 Show InChI InChI=1S/C20H22ClFN2O/c21-17-3-1-2-16(12-17)13-20(25)23-19-8-10-24(11-9-19)14-15-4-6-18(22)7-5-15/h1-7,12,19H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107212 (2-(3-Bromo-phenyl)-N-[1-(4-fluoro-benzyl)-piperidi...) Show SMILES Fc1ccc(CN2CCC(CC2)NC(=O)Cc2cccc(Br)c2)cc1 Show InChI InChI=1S/C20H22BrFN2O/c21-17-3-1-2-16(12-17)13-20(25)23-19-8-10-24(11-9-19)14-15-4-6-18(22)7-5-15/h1-7,12,19H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107223 (2-(3-Bromo-phenyl)-N-[1-(4-iodo-benzyl)-piperidin-...) Show SMILES Brc1cccc(CC(=O)NC2CCN(Cc3ccc(I)cc3)CC2)c1 Show InChI InChI=1S/C20H22BrIN2O/c21-17-3-1-2-16(12-17)13-20(25)23-19-8-10-24(11-9-19)14-15-4-6-18(22)7-5-15/h1-7,12,19H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107195 (2-(3-Fluoro-phenyl)-N-[1-(4-iodo-benzyl)-piperidin...) Show SMILES Fc1cccc(CC(=O)NC2CCN(Cc3ccc(I)cc3)CC2)c1 Show InChI InChI=1S/C20H22FIN2O/c21-17-3-1-2-16(12-17)13-20(25)23-19-8-10-24(11-9-19)14-15-4-6-18(22)7-5-15/h1-7,12,19H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107203 (2-(3-Chloro-phenyl)-N-[1-(3-iodo-benzyl)-piperidin...) Show SMILES Clc1cccc(CC(=O)NC2CCN(Cc3cccc(I)c3)CC2)c1 Show InChI InChI=1S/C20H22ClIN2O/c21-17-5-1-3-15(11-17)13-20(25)23-19-7-9-24(10-8-19)14-16-4-2-6-18(22)12-16/h1-6,11-12,19H,7-10,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	2.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107211 (CHEMBL135083 | N-[1-(4-Fluoro-benzyl)-piperidin-4-...) Show SMILES Fc1ccc(CN2CCC(CC2)NC(=O)Cc2ccccc2F)cc1 Show InChI InChI=1S/C20H22F2N2O/c21-17-7-5-15(6-8-17)14-24-11-9-18(10-12-24)23-20(25)13-16-3-1-2-4-19(16)22/h1-8,18H,9-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107201 (2-(3-Chloro-phenyl)-N-[1-(4-iodo-benzyl)-piperidin...) Show SMILES Clc1cccc(CC(=O)NC2CCN(Cc3ccc(I)cc3)CC2)c1 Show InChI InChI=1S/C20H22ClIN2O/c21-17-3-1-2-16(12-17)13-20(25)23-19-8-10-24(11-9-19)14-15-4-6-18(22)7-5-15/h1-7,12,19H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107227 (2-(3-Bromo-phenyl)-N-[1-(3-iodo-benzyl)-piperidin-...) Show SMILES Brc1cccc(CC(=O)NC2CCN(Cc3cccc(I)c3)CC2)c1 Show InChI InChI=1S/C20H22BrIN2O/c21-17-5-1-3-15(11-17)13-20(25)23-19-7-9-24(10-8-19)14-16-4-2-6-18(22)12-16/h1-6,11-12,19H,7-10,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064947 (CHEMBL76895 | N-(1-Benzyl-piperidin-4-yl)-2-phenyl...) Show SMILES O=C(Cc1ccccc1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H24N2O/c23-20(15-17-7-3-1-4-8-17)21-19-11-13-22(14-12-19)16-18-9-5-2-6-10-18/h1-10,19H,11-16H2,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107208 (CHEMBL138688 | N-(1-Benzyl-piperidin-4-yl)-2-thiop...) Show SMILES O=C(Cc1cccs1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C18H22N2OS/c21-18(13-17-7-4-12-22-17)19-16-8-10-20(11-9-16)14-15-5-2-1-3-6-15/h1-7,12,16H,8-11,13-14H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	3.93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107198 (CHEMBL335953 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-pi...) Show SMILES O=C(Cc1ccccc1)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C21H24N2O3/c24-21(13-16-4-2-1-3-5-16)22-18-8-10-23(11-9-18)14-17-6-7-19-20(12-17)26-15-25-19/h1-7,12,18H,8-11,13-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107221 (2-(2-Fluoro-phenyl)-N-[1-(4-iodo-benzyl)-piperidin...) Show SMILES Fc1ccccc1CC(=O)NC1CCN(Cc2ccc(I)cc2)CC1 Show InChI InChI=1S/C20H22FIN2O/c21-19-4-2-1-3-16(19)13-20(25)23-18-9-11-24(12-10-18)14-15-5-7-17(22)8-6-15/h1-8,18H,9-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107232 (2-(3-Fluoro-phenyl)-N-[1-(3-iodo-benzyl)-piperidin...) Show SMILES Fc1cccc(CC(=O)NC2CCN(Cc3cccc(I)c3)CC2)c1 Show InChI InChI=1S/C20H22FIN2O/c21-17-5-1-3-15(11-17)13-20(25)23-19-7-9-24(10-8-19)14-16-4-2-6-18(22)12-16/h1-6,11-12,19H,7-10,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107230 (CHEMBL336037 | N-(1-Benzyl-piperidin-4-yl)-2-napht...) Show SMILES O=C(Cc1cccc2ccccc12)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C24H26N2O/c27-24(17-21-11-6-10-20-9-4-5-12-23(20)21)25-22-13-15-26(16-14-22)18-19-7-2-1-3-8-19/h1-12,22H,13-18H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	4.64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107216 (CHEMBL136451 | N-[1-(4-Fluoro-benzyl)-piperidin-4-...) Show SMILES Fc1ccc(CN2CCC(CC2)NC(=O)Cc2cccc(F)c2)cc1 Show InChI InChI=1S/C20H22F2N2O/c21-17-6-4-15(5-7-17)14-24-10-8-19(9-11-24)23-20(25)13-16-2-1-3-18(22)12-16/h1-7,12,19H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107226 (CHEMBL344023 | N-[1-(3,4-Difluoro-benzyl)-piperidi...) Show SMILES Fc1ccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)cc1F Show InChI InChI=1S/C20H22F2N2O/c21-18-7-6-16(12-19(18)22)14-24-10-8-17(9-11-24)23-20(25)13-15-4-2-1-3-5-15/h1-7,12,17H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107224 (CHEMBL341957 | N-[1-(4-Fluoro-benzyl)-piperidin-4-...) Show SMILES Fc1ccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C20H23FN2O/c21-18-8-6-17(7-9-18)15-23-12-10-19(11-13-23)22-20(24)14-16-4-2-1-3-5-16/h1-9,19H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107219 (CHEMBL137675 | N-[1-(3-Iodo-benzyl)-piperidin-4-yl...) Show SMILES Ic1cccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)c1 Show InChI InChI=1S/C20H23IN2O/c21-18-8-4-7-17(13-18)15-23-11-9-19(10-12-23)22-20(24)14-16-5-2-1-3-6-16/h1-8,13,19H,9-12,14-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107199 (CHEMBL138249 | N-(1-Benzyl-piperidin-4-yl)-2-thiop...) Show SMILES O=C(Cc1ccsc1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C18H22N2OS/c21-18(12-16-8-11-22-14-16)19-17-6-9-20(10-7-17)13-15-4-2-1-3-5-15/h1-5,8,11,14,17H,6-7,9-10,12-13H2,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107194 (CHEMBL139156 | N-[1-(3,4-Dichloro-benzyl)-piperidi...) Show SMILES Clc1ccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)cc1Cl Show InChI InChI=1S/C20H22Cl2N2O/c21-18-7-6-16(12-19(18)22)14-24-10-8-17(9-11-24)23-20(25)13-15-4-2-1-3-5-15/h1-7,12,17H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	7.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107197 (CHEMBL139629 | N-[1-(3-Fluoro-benzyl)-piperidin-4-...) Show SMILES Fc1cccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)c1 Show InChI InChI=1S/C20H23FN2O/c21-18-8-4-7-17(13-18)15-23-11-9-19(10-12-23)22-20(24)14-16-5-2-1-3-6-16/h1-8,13,19H,9-12,14-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8.22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107210 (CHEMBL139735 | N-[1-(4-Iodo-benzyl)-piperidin-4-yl...) Show SMILES Ic1ccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C20H23IN2O/c21-18-8-6-17(7-9-18)15-23-12-10-19(11-13-23)22-20(24)14-16-4-2-1-3-5-16/h1-9,19H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.03	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107231 (CHEMBL345051 | N-[1-(2-Fluoro-benzyl)-piperidin-4-...) Show SMILES Fc1ccccc1CN1CCC(CC1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C20H23FN2O/c21-19-9-5-4-8-17(19)15-23-12-10-18(11-13-23)22-20(24)14-16-6-2-1-3-7-16/h1-9,18H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107229 (CHEMBL341936 | N-(1-Benzyl-piperidin-4-yl)-2-(1H-i...) Show SMILES O=C(Cc1c[nH]c2ccccc12)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H25N3O/c26-22(14-18-15-23-21-9-5-4-8-20(18)21)24-19-10-12-25(13-11-19)16-17-6-2-1-3-7-17/h1-9,15,19,23H,10-14,16H2,(H,24,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107202 (CHEMBL344402 | N-(1-Benzyl-piperidin-4-yl)-2-(4-io...) Show SMILES Ic1ccc(CC(=O)NC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H23IN2O/c21-18-8-6-16(7-9-18)14-20(24)22-19-10-12-23(13-11-19)15-17-4-2-1-3-5-17/h1-9,19H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50064946 (4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydro...) Show SMILES OC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	14.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107222 (2-(2-Fluoro-phenyl)-N-[1-(3-iodo-benzyl)-piperidin...) Show SMILES Fc1ccccc1CC(=O)NC1CCN(Cc2cccc(I)c2)CC1 Show InChI InChI=1S/C20H22FIN2O/c21-19-7-2-1-5-16(19)13-20(25)23-18-8-10-24(11-9-18)14-15-4-3-6-17(22)12-15/h1-7,12,18H,8-11,13-14H2,(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107209 (CHEMBL344186 | N-[1-(4-Nitro-benzyl)-piperidin-4-y...) Show SMILES [O-][N+](=O)c1ccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C20H23N3O3/c24-20(14-16-4-2-1-3-5-16)21-18-10-12-22(13-11-18)15-17-6-8-19(9-7-17)23(25)26/h1-9,18H,10-15H2,(H,21,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107214 (1-(1-Benzyl-piperidin-4-yl)-3-naphthalen-1-yl-urea...) Show SMILES O=C(NC1CCN(Cc2ccccc2)CC1)Nc1cccc2ccccc12 Show InChI InChI=1S/C23H25N3O/c27-23(25-22-12-6-10-19-9-4-5-11-21(19)22)24-20-13-15-26(16-14-20)17-18-7-2-1-3-8-18/h1-12,20H,13-17H2,(H2,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	22.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107213 (CHEMBL136677 | N-(1-Naphthalen-2-ylmethyl-piperidi...) Show SMILES O=C(Cc1ccccc1)NC1CCN(Cc2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C24H26N2O/c27-24(17-19-6-2-1-3-7-19)25-23-12-14-26(15-13-23)18-20-10-11-21-8-4-5-9-22(21)16-20/h1-11,16,23H,12-15,17-18H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107200 (CHEMBL136275 | N-(1-Phenethyl-piperidin-4-yl)-2-ph...) Show SMILES O=C(Cc1ccccc1)NC1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C21H26N2O/c24-21(17-19-9-5-2-6-10-19)22-20-12-15-23(16-13-20)14-11-18-7-3-1-4-8-18/h1-10,20H,11-17H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	31.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107217 (CHEMBL139922 | N-(1-Benzyl-piperidin-4-yl)-2-(5-br...) Show SMILES Brc1ccc2[nH]cc(CC(=O)NC3CCN(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C22H24BrN3O/c23-18-6-7-21-20(13-18)17(14-24-21)12-22(27)25-19-8-10-26(11-9-19)15-16-4-2-1-3-5-16/h1-7,13-14,19,24H,8-12,15H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	51.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107215 (CHEMBL134856 | N-(1-Benzyl-piperidin-4-yl)-2-napht...) Show SMILES O=C(Cc1ccc2ccccc2c1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C24H26N2O/c27-24(17-20-10-11-21-8-4-5-9-22(21)16-20)25-23-12-14-26(15-13-23)18-19-6-2-1-3-7-19/h1-11,16,23H,12-15,17-18H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	61.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107196 (2-Phenyl-N-[1-(4-trifluoromethyl-benzyl)-piperidin...) Show SMILES FC(F)(F)c1ccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C21H23F3N2O/c22-21(23,24)18-8-6-17(7-9-18)15-26-12-10-19(11-13-26)25-20(27)14-16-4-2-1-3-5-16/h1-9,19H,10-15H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	87.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107220 (CHEMBL442408 | N-(1-Benzyl-piperidin-4-yl)-2-(5-me...) Show SMILES COc1ccc2[nH]cc(CC(=O)NC3CCN(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C23H27N3O2/c1-28-20-7-8-22-21(14-20)18(15-24-22)13-23(27)25-19-9-11-26(12-10-19)16-17-5-3-2-4-6-17/h2-8,14-15,19,24H,9-13,16H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107207 (2-Phenyl-N-[1-(3-trifluoromethyl-benzyl)-piperidin...) Show SMILES FC(F)(F)c1cccc(CN2CCC(CC2)NC(=O)Cc2ccccc2)c1 Show InChI InChI=1S/C21H23F3N2O/c22-21(23,24)18-8-4-7-17(13-18)15-26-11-9-19(10-12-26)25-20(27)14-16-5-2-1-3-6-16/h1-8,13,19H,9-12,14-15H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107191 (CHEMBL344873 | N-(1-Benzyl-piperidin-4-yl)-2-(pyri...) Show SMILES O=C(CSc1ncccn1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C18H22N4OS/c23-17(14-24-18-19-9-4-10-20-18)21-16-7-11-22(12-8-16)13-15-5-2-1-3-6-15/h1-6,9-10,16H,7-8,11-14H2,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107204 (CHEMBL138894 | N-(1-Benzyl-piperidin-4-yl)-2-pyrid...) Show SMILES O=C(Cc1ccccn1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H23N3O/c23-19(14-18-8-4-5-11-20-18)21-17-9-12-22(13-10-17)15-16-6-2-1-3-7-16/h1-8,11,17H,9-10,12-15H2,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	236	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107192 (CHEMBL138393 | N-(1-Benzyl-piperidin-4-yl)-2-(1H-i...) Show SMILES O=C(Cc1cnc[nH]1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C17H22N4O/c22-17(10-16-11-18-13-19-16)20-15-6-8-21(9-7-15)12-14-4-2-1-3-5-14/h1-5,11,13,15H,6-10,12H2,(H,18,19)(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	248	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107228 (CHEMBL137606 | N-(1-Benzyl-piperidin-4-yl)-2-pyrid...) Show SMILES O=C(Cc1cccnc1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H23N3O/c23-19(13-17-7-4-10-20-14-17)21-18-8-11-22(12-9-18)15-16-5-2-1-3-6-16/h1-7,10,14,18H,8-9,11-13,15H2,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	269	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107205 (CHEMBL136989 | N-(1-Benzyl-piperidin-4-yl)-2-pyrid...) Show SMILES O=C(Cc1ccncc1)NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H23N3O/c23-19(14-16-6-10-20-11-7-16)21-18-8-12-22(13-9-18)15-17-4-2-1-3-5-17/h1-7,10-11,18H,8-9,12-15H2,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	298	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107218 (CHEMBL138932 | N-(1-Benzyl-piperidin-4-yl)-2-(6-me...) Show SMILES COc1ccc2C(=O)CC(CC(=O)NC3CCN(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C24H28N2O3/c1-29-20-7-8-21-22(15-20)18(13-23(21)27)14-24(28)25-19-9-11-26(12-10-19)16-17-5-3-2-4-6-17/h2-8,15,18-19H,9-14,16H2,1H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	299	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107206 (CHEMBL343927 | N-[1-(2-Iodo-benzyl)-piperidin-4-yl...) Show SMILES Ic1ccccc1CN1CCC(CC1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C20H23IN2O/c21-19-9-5-4-8-17(19)15-23-12-10-18(11-13-23)22-20(24)14-16-6-2-1-3-7-16/h1-9,18H,10-15H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	347	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107233 (2-Phenyl-N-[1-(2-trifluoromethyl-benzyl)-piperidin...) Show SMILES FC(F)(F)c1ccccc1CN1CCC(CC1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C21H23F3N2O/c22-21(23,24)19-9-5-4-8-17(19)15-26-12-10-18(11-13-26)25-20(27)14-16-6-2-1-3-7-16/h1-9,18H,10-15H2,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50107193 (CHEMBL136163 | N-(1-Benzyl-piperidin-4-yl)-2-(7-hy...) Show SMILES O=C(CC1=CC(=O)OC2CC(=O)C=CC12)NC1CCN(Cc2ccccc2)CC1 |c:12,t:3| Show InChI InChI=1S/C23H26N2O4/c26-19-6-7-20-17(13-23(28)29-21(20)14-19)12-22(27)24-18-8-10-25(11-9-18)15-16-4-2-1-3-5-16/h1-7,13,18,20-21H,8-12,14-15H2,(H,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma 1 opioid receptor, measured on guinea pig brain membranes using [3H]- (+)-pentazocine as radioligand				J Med Chem 44: 4404-15 (2001) BindingDB Entry DOI: 10.7270/Q2S46R7N
					More data for this Ligand-Target Pair