Compile Data Set for Download or QSAR

Found 66 hits Enz. Inhib. hit(s) with all data for entry = 50014695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146351 (CHEMBL329566 | Dimethyl-[(2R,3aR,12bS)-1-(3,3a,8,1...) Show SMILES CN(C)C[C@H]1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146357 (CHEMBL329268 | Dimethyl-[(2S,3aR,12bS)-1-(3,3a,8,1...) Show SMILES CN(C)C[C@@H]1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19+,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146360 (CHEMBL328573 | Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetr...) Show SMILES CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146348 (CHEMBL92667 | Dimethyl-[(3aR,12bS)-1-(3,3a,8,12b-t...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16?,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146351 (CHEMBL329566 | Dimethyl-[(2R,3aR,12bS)-1-(3,3a,8,1...) Show SMILES CN(C)C[C@H]1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146360 (CHEMBL328573 | Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetr...) Show SMILES CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146340 (1-Methyl-4-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-...) Show SMILES CN1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Sc2ccccc32)CC1 Show InChI InChI=1S/C22H26N2OS/c1-23-10-12-24(13-11-23)15-16-14-19-17-6-2-4-8-20(17)26-21-9-5-3-7-18(21)22(19)25-16/h2-9,16,19,22H,10-15H2,1H3/t16?,19-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146343 ((4-Fluoro-phenyl)-{1-[(3aR,12bS)-1-(3,3a,8,12b-tet...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Cc2ccccc32)CC1 Show InChI InChI=1S/C30H30FNO2/c31-24-11-9-20(10-12-24)29(33)21-13-15-32(16-14-21)19-25-18-28-26-7-3-1-5-22(26)17-23-6-2-4-8-27(23)30(28)34-25/h1-12,21,25,28,30H,13-19H2/t25?,28-,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146353 (4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa-di...) Show SMILES C(C1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21)N1CCOCC1 Show InChI InChI=1S/C22H25NO2/c1-3-7-19-16(5-1)13-17-6-2-4-8-20(17)22-21(19)14-18(25-22)15-23-9-11-24-12-10-23/h1-8,18,21-22H,9-15H2/t18?,21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146360 (CHEMBL328573 | Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetr...) Show SMILES CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146351 (CHEMBL329566 | Dimethyl-[(2R,3aR,12bS)-1-(3,3a,8,1...) Show SMILES CN(C)C[C@H]1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146350 (1-Methyl-4-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H...) Show SMILES CN1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Cc2ccccc32)CC1 Show InChI InChI=1S/C23H28N2O/c1-24-10-12-25(13-11-24)16-19-15-22-20-8-4-2-6-17(20)14-18-7-3-5-9-21(18)23(22)26-19/h2-9,19,22-23H,10-16H2,1H3/t19?,22-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146357 (CHEMBL329268 | Dimethyl-[(2S,3aR,12bS)-1-(3,3a,8,1...) Show SMILES CN(C)C[C@@H]1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19+,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50404245 (CHEMBL2112371) Show SMILES CNC[C@@H]1C[C@@H]2[C@@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H21NO/c1-20-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)19(18)21-15/h2-9,15,18-20H,10-12H2,1H3/t15-,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146342 (CHEMBL327651 | Dimethyl-[(2S,3aS,12bR)-1-(3,3a,8,1...) Show SMILES CN(C)C[C@@H]1C[C@@H]2[C@@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19-,20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146354 (2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa...) Show SMILES OCCN1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Cc2ccccc32)CC1 Show InChI InChI=1S/C24H30N2O2/c27-14-13-25-9-11-26(12-10-25)17-20-16-23-21-7-3-1-5-18(21)15-19-6-2-4-8-22(19)24(23)28-20/h1-8,20,23-24,27H,9-17H2/t20?,23-,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146347 (CHEMBL327306 | Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Sc1ccccc21 Show InChI InChI=1S/C19H21NOS/c1-20(2)12-13-11-16-14-7-3-5-9-17(14)22-18-10-6-4-8-15(18)19(16)21-13/h3-10,13,16,19H,11-12H2,1-2H3/t13?,16-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146356 (CHEMBL328356 | Dimethyl-((3aR,12bS)-8-methyl-3,3a,...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1N(C)c1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)13-14-12-17-15-8-4-6-10-18(15)22(3)19-11-7-5-9-16(19)20(17)23-14/h4-11,14,17,20H,12-13H2,1-3H3/t14?,17-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146348 (CHEMBL92667 | Dimethyl-[(3aR,12bS)-1-(3,3a,8,12b-t...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16?,19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146352 (CHEMBL329685 | Methyl-[(3aR,12bS)-1-(3,3a,8,12b-te...) Show SMILES CNCC1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H21NO/c1-20-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)19(18)21-15/h2-9,15,18-20H,10-12H2,1H3/t15?,18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146339 (CHEMBL93321 | N,N-dimethyl-(3aR,13bS)-2H,9H-dibenz...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1COc1ccccc21 Show InChI InChI=1S/C20H23NO2/c1-21(2)12-15-11-18-17-9-5-6-10-19(17)22-13-14-7-3-4-8-16(14)20(18)23-15/h3-10,15,18,20H,11-13H2,1-2H3/t15?,18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146352 (CHEMBL329685 | Methyl-[(3aR,12bS)-1-(3,3a,8,12b-te...) Show SMILES CNCC1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H21NO/c1-20-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)19(18)21-15/h2-9,15,18-20H,10-12H2,1H3/t15?,18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146356 (CHEMBL328356 | Dimethyl-((3aR,12bS)-8-methyl-3,3a,...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1N(C)c1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)13-14-12-17-15-8-4-6-10-18(15)22(3)19-11-7-5-9-16(19)20(17)23-14/h4-11,14,17,20H,12-13H2,1-3H3/t14?,17-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146345 (CHEMBL96158 | Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-t...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Oc1ccccc21 Show InChI InChI=1S/C19H21NO2/c1-20(2)12-13-11-16-14-7-3-5-9-17(14)22-18-10-6-4-8-15(18)19(16)21-13/h3-10,13,16,19H,11-12H2,1-2H3/t13?,16-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50404245 (CHEMBL2112371) Show SMILES CNC[C@@H]1C[C@@H]2[C@@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H21NO/c1-20-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)19(18)21-15/h2-9,15,18-20H,10-12H2,1H3/t15-,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146340 (1-Methyl-4-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-...) Show SMILES CN1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Sc2ccccc32)CC1 Show InChI InChI=1S/C22H26N2OS/c1-23-10-12-24(13-11-23)15-16-14-19-17-6-2-4-8-20(17)26-21-9-5-3-7-18(21)22(19)25-16/h2-9,16,19,22H,10-15H2,1H3/t16?,19-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146343 ((4-Fluoro-phenyl)-{1-[(3aR,12bS)-1-(3,3a,8,12b-tet...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Cc2ccccc32)CC1 Show InChI InChI=1S/C30H30FNO2/c31-24-11-9-20(10-12-24)29(33)21-13-15-32(16-14-21)19-25-18-28-26-7-3-1-5-22(26)17-23-6-2-4-8-27(23)30(28)34-25/h1-12,21,25,28,30H,13-19H2/t25?,28-,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146357 (CHEMBL329268 | Dimethyl-[(2S,3aR,12bS)-1-(3,3a,8,1...) Show SMILES CN(C)C[C@@H]1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19+,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146341 (CHEMBL328209 | N,N-dimethyl-(3aR,13bS)-2H,8H-diben...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1OCc1ccccc21 Show InChI InChI=1S/C20H23NO2/c1-21(2)12-15-11-18-16-8-4-3-7-14(16)13-22-19-10-6-5-9-17(19)20(18)23-15/h3-10,15,18,20H,11-13H2,1-2H3/t15?,18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146348 (CHEMBL92667 | Dimethyl-[(3aR,12bS)-1-(3,3a,8,12b-t...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16?,19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146347 (CHEMBL327306 | Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Sc1ccccc21 Show InChI InChI=1S/C19H21NOS/c1-20(2)12-13-11-16-14-7-3-5-9-17(14)22-18-10-6-4-8-15(18)19(16)21-13/h3-10,13,16,19H,11-12H2,1-2H3/t13?,16-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146355 (CHEMBL96732 | Dimethyl-[(3aS,12bS)-1-(3,3a,8,12b-t...) Show SMILES CN(C)CC1C[C@@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16?,19-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146353 (4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa-di...) Show SMILES C(C1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21)N1CCOCC1 Show InChI InChI=1S/C22H25NO2/c1-3-7-19-16(5-1)13-17-6-2-4-8-20(17)22-21(19)14-18(25-22)15-23-9-11-24-12-10-23/h1-8,18,21-22H,9-15H2/t18?,21-,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146342 (CHEMBL327651 | Dimethyl-[(2S,3aS,12bR)-1-(3,3a,8,1...) Show SMILES CN(C)C[C@@H]1C[C@@H]2[C@@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C20H23NO/c1-21(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)20(19)22-16/h3-10,16,19-20H,11-13H2,1-2H3/t16-,19-,20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146358 (4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H...) Show SMILES C(C1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C29H31NO/c1-2-8-21(9-3-1)22-14-16-30(17-15-22)20-25-19-28-26-12-6-4-10-23(26)18-24-11-5-7-13-27(24)29(28)31-25/h1-13,22,25,28-29H,14-20H2/t25?,28-,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146345 (CHEMBL96158 | Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-t...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Oc1ccccc21 Show InChI InChI=1S/C19H21NO2/c1-20(2)12-13-11-16-14-7-3-5-9-17(14)22-18-10-6-4-8-15(18)19(16)21-13/h3-10,13,16,19H,11-12H2,1-2H3/t13?,16-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146347 (CHEMBL327306 | Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Sc1ccccc21 Show InChI InChI=1S/C19H21NOS/c1-20(2)12-13-11-16-14-7-3-5-9-17(14)22-18-10-6-4-8-15(18)19(16)21-13/h3-10,13,16,19H,11-12H2,1-2H3/t13?,16-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146344 (CHEMBL330713 | Dimethyl-[(3aS,12bS)-1-(2,3,3a,12b-...) Show SMILES CN(C)CC1C[C@@H]2[C@H](O1)c1ccccc1Oc1ccccc21 Show InChI InChI=1S/C19H21NO2/c1-20(2)12-13-11-16-14-7-3-5-9-17(14)22-18-10-6-4-8-15(18)19(16)21-13/h3-10,13,16,19H,11-12H2,1-2H3/t13?,16-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146339 (CHEMBL93321 | N,N-dimethyl-(3aR,13bS)-2H,9H-dibenz...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1COc1ccccc21 Show InChI InChI=1S/C20H23NO2/c1-21(2)12-15-11-18-17-9-5-6-10-19(17)22-13-14-7-3-4-8-16(14)20(18)23-15/h3-10,15,18,20H,11-13H2,1-2H3/t15?,18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146345 (CHEMBL96158 | Dimethyl-[(3aR,12bS)-1-(2,3,3a,12b-t...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1Oc1ccccc21 Show InChI InChI=1S/C19H21NO2/c1-20(2)12-13-11-16-14-7-3-5-9-17(14)22-18-10-6-4-8-15(18)19(16)21-13/h3-10,13,16,19H,11-12H2,1-2H3/t13?,16-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50146358 (4-Phenyl-1-[(3aR,12bS)-1-(3,3a,8,12b-tetrahydro-2H...) Show SMILES C(C1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C29H31NO/c1-2-8-21(9-3-1)22-14-16-30(17-15-22)20-25-19-28-26-12-6-4-10-23(26)18-24-11-5-7-13-27(24)29(28)31-25/h1-13,22,25,28-29H,14-20H2/t25?,28-,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]- mesulergine from human cloned 5-hydroxytryptamine 2C receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50146346 (4-Phenyl-1-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-...) Show SMILES C(C1C[C@H]2[C@H](O1)c1ccccc1Sc1ccccc21)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C28H29NOS/c1-2-8-20(9-3-1)21-14-16-29(17-15-21)19-22-18-25-23-10-4-6-12-26(23)31-27-13-7-5-11-24(27)28(25)30-22/h1-13,21-22,25,28H,14-19H2/t22?,25-,28-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [3H]-pyrilamine from human cloned histamine H1 receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146352 (CHEMBL329685 | Methyl-[(3aR,12bS)-1-(3,3a,8,12b-te...) Show SMILES CNCC1C[C@H]2[C@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H21NO/c1-20-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)19(18)21-15/h2-9,15,18-20H,10-12H2,1H3/t15?,18-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146359 (1-(3-Chloro-phenyl)-4-[(3aR,12bS)-1-(3,3a,8,12b-te...) Show SMILES Clc1cccc(c1)N1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Cc2ccccc32)CC1 Show InChI InChI=1S/C28H29ClN2O/c29-22-8-5-9-23(17-22)31-14-12-30(13-15-31)19-24-18-27-25-10-3-1-6-20(25)16-21-7-2-4-11-26(21)28(27)32-24/h1-11,17,24,27-28H,12-16,18-19H2/t24?,27-,28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146346 (4-Phenyl-1-[(3aR,12bS)-1-(2,3,3a,12b-tetrahydro-1-...) Show SMILES C(C1C[C@H]2[C@H](O1)c1ccccc1Sc1ccccc21)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C28H29NOS/c1-2-8-20(9-3-1)21-14-16-29(17-15-21)19-22-18-25-23-10-4-6-12-26(23)31-27-13-7-5-11-24(27)28(25)30-22/h1-13,21-22,25,28H,14-19H2/t22?,25-,28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50404245 (CHEMBL2112371) Show SMILES CNC[C@@H]1C[C@@H]2[C@@H](O1)c1ccccc1Cc1ccccc21 Show InChI InChI=1S/C19H21NO/c1-20-12-15-11-18-16-8-4-2-6-13(16)10-14-7-3-5-9-17(14)19(18)21-15/h2-9,15,18-20H,10-12H2,1H3/t15-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146356 (CHEMBL328356 | Dimethyl-((3aR,12bS)-8-methyl-3,3a,...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1N(C)c1ccccc21 Show InChI InChI=1S/C20H24N2O/c1-21(2)13-14-12-17-15-8-4-6-10-18(15)22(3)19-11-7-5-9-16(19)20(17)23-14/h4-11,14,17,20H,12-13H2,1-3H3/t14?,17-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146354 (2-{4-[(3aR,12bS)-1-(3,3a,8,12b-Tetrahydro-2H-1-oxa...) Show SMILES OCCN1CCN(CC2C[C@H]3[C@H](O2)c2ccccc2Cc2ccccc32)CC1 Show InChI InChI=1S/C24H30N2O2/c27-14-13-25-9-11-26(12-10-25)17-20-16-23-21-7-3-1-5-18(21)15-19-6-2-4-8-22(19)24(23)28-20/h1-8,20,23-24,27H,9-17H2/t20?,23-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146339 (CHEMBL93321 | N,N-dimethyl-(3aR,13bS)-2H,9H-dibenz...) Show SMILES CN(C)CC1C[C@H]2[C@H](O1)c1ccccc1COc1ccccc21 Show InChI InChI=1S/C20H23NO2/c1-21(2)12-15-11-18-17-9-5-6-10-19(17)22-13-14-7-3-4-8-16(14)20(18)23-15/h3-10,15,18,20H,11-13H2,1-2H3/t15?,18-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50146344 (CHEMBL330713 | Dimethyl-[(3aS,12bS)-1-(2,3,3a,12b-...) Show SMILES CN(C)CC1C[C@@H]2[C@H](O1)c1ccccc1Oc1ccccc21 Show InChI InChI=1S/C19H21NO2/c1-20(2)12-13-11-16-14-7-3-5-9-17(14)22-18-10-6-4-8-15(18)19(16)21-13/h3-10,13,16,19H,11-12H2,1-2H3/t13?,16-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Ability to displace [125I]-R91150 from human cloned 5-hydroxytryptamine 2A receptor expressed in L929 cells				Bioorg Med Chem Lett 14: 2765-71 (2004) Article DOI: 10.1016/j.bmcl.2004.03.069 BindingDB Entry DOI: 10.7270/Q21835ZF
					More data for this Ligand-Target Pair

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