Compile Data Set for Download or QSAR

Found 64 hits Enz. Inhib. hit(s) with all data for entry = 50015355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155213 (1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-8-yl-u...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2ccncc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)12-4-1-5-12)20-14-6-2-3-11-7-8-18-9-13(11)14/h2-3,6-10,12H,1,4-5H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155231 (2-(1H-Benzoimidazol-5-yl)-N-(5-cyclobutyl-thiazol-...) Show SMILES O=C(Cc1ccc2nc[nH]c2c1)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C16H16N4OS/c21-15(7-10-4-5-12-13(6-10)19-9-18-12)20-16-17-8-14(22-16)11-2-1-3-11/h4-6,8-9,11H,1-3,7H2,(H,18,19)(H,17,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155209 (1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-5-yl-u...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2cnccc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-3-1-4-11)20-14-6-2-5-12-9-18-8-7-13(12)14/h2,5-11H,1,3-4H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155236 (CHEMBL363954 | N-(5-Cyclobutyl-thiazol-2-yl)-2-qui...) Show SMILES O=C(Cc1ccc2ncccc2c1)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C18H17N3OS/c22-17(21-18-20-11-16(23-18)13-3-1-4-13)10-12-6-7-15-14(9-12)5-2-8-19-15/h2,5-9,11,13H,1,3-4,10H2,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155235 (CHEMBL186470 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-...) Show SMILES Cc1nc2ccc(CC(=O)Nc3ncc(s3)C3CCC3)cc2s1 Show InChI InChI=1S/C17H17N3OS2/c1-10-19-13-6-5-11(7-14(13)22-10)8-16(21)20-17-18-9-15(23-17)12-3-2-4-12/h5-7,9,12H,2-4,8H2,1H3,(H,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155207 (1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-5-yl-urea...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2ncccc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-4-1-5-11)20-14-8-2-7-13-12(14)6-3-9-18-13/h2-3,6-11H,1,4-5H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155230 (CHEMBL187903 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(5,...) Show SMILES Cc1cc2ncn(CC(=O)Nc3ncc(s3)C3CCC3)c2cc1C Show InChI InChI=1S/C18H20N4OS/c1-11-6-14-15(7-12(11)2)22(10-20-14)9-17(23)21-18-19-8-16(24-18)13-4-3-5-13/h6-8,10,13H,3-5,9H2,1-2H3,(H,19,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155237 (CHEMBL184404 | N-(5-Cyclobutyl-thiazol-2-yl)-2-iso...) Show SMILES O=C(Cc1cccc2cnccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C18H17N3OS/c22-17(21-18-20-11-16(23-18)12-3-1-4-12)9-13-5-2-6-14-10-19-8-7-15(13)14/h2,5-8,10-12H,1,3-4,9H2,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155214 (CHEMBL186240 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(1H...) Show SMILES O=C(Cc1c[nH]c2ccccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C17H17N3OS/c21-16(8-12-9-18-14-7-2-1-6-13(12)14)20-17-19-10-15(22-17)11-4-3-5-11/h1-2,6-7,9-11,18H,3-5,8H2,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155235 (CHEMBL186470 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-...) Show SMILES Cc1nc2ccc(CC(=O)Nc3ncc(s3)C3CCC3)cc2s1 Show InChI InChI=1S/C17H17N3OS2/c1-10-19-13-6-5-11(7-14(13)22-10)8-16(21)20-17-18-9-15(23-17)12-3-2-4-12/h5-7,9,12H,2-4,8H2,1H3,(H,18,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155225 (CHEMBL365855 | N-(5-Cyclobutyl-thiazol-2-yl)-2-phe...) Show SMILES O=C(Cc1ccccc1)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C15H16N2OS/c18-14(9-11-5-2-1-3-6-11)17-15-16-10-13(19-15)12-7-4-8-12/h1-3,5-6,10,12H,4,7-9H2,(H,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155230 (CHEMBL187903 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(5,...) Show SMILES Cc1cc2ncn(CC(=O)Nc3ncc(s3)C3CCC3)c2cc1C Show InChI InChI=1S/C18H20N4OS/c1-11-6-14-15(7-12(11)2)22(10-20-14)9-17(23)21-18-19-8-16(24-18)13-4-3-5-13/h6-8,10,13H,3-5,9H2,1-2H3,(H,19,21,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155236 (CHEMBL363954 | N-(5-Cyclobutyl-thiazol-2-yl)-2-qui...) Show SMILES O=C(Cc1ccc2ncccc2c1)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C18H17N3OS/c22-17(21-18-20-11-16(23-18)13-3-1-4-13)10-12-6-7-15-14(9-12)5-2-8-19-15/h2,5-9,11,13H,1,3-4,10H2,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155231 (2-(1H-Benzoimidazol-5-yl)-N-(5-cyclobutyl-thiazol-...) Show SMILES O=C(Cc1ccc2nc[nH]c2c1)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C16H16N4OS/c21-15(7-10-4-5-12-13(6-10)19-9-18-12)20-16-17-8-14(22-16)11-2-1-3-11/h4-6,8-9,11H,1-3,7H2,(H,18,19)(H,17,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155214 (CHEMBL186240 | N-(5-Cyclobutyl-thiazol-2-yl)-2-(1H...) Show SMILES O=C(Cc1c[nH]c2ccccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C17H17N3OS/c21-16(8-12-9-18-14-7-2-1-6-13(12)14)20-17-19-10-15(22-17)11-4-3-5-11/h1-2,6-7,9-11,18H,3-5,8H2,(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155232 (1-(3H-Benzotriazol-4-yl)-3-(5-cyclobutyl-thiazol-2...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2nn[nH]c12 Show InChI InChI=1S/C14H14N6OS/c21-13(16-9-5-2-6-10-12(9)19-20-18-10)17-14-15-7-11(22-14)8-3-1-4-8/h2,5-8H,1,3-4H2,(H,18,19,20)(H2,15,16,17,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155207 (1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-5-yl-urea...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2ncccc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-4-1-5-11)20-14-8-2-7-13-12(14)6-3-9-18-13/h2-3,6-11H,1,4-5H2,(H2,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155221 (1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-6-yl-urea...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1ccc2ncccc2c1 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-3-1-4-11)20-13-6-7-14-12(9-13)5-2-8-18-14/h2,5-11H,1,3-4H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155222 (1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-6-yl-u...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1ccc2cnccc2c1 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-2-1-3-11)20-14-5-4-13-9-18-7-6-12(13)8-14/h4-11H,1-3H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155220 (CHEMBL364338 | N-(5-Cyclobutyl-thiazol-2-yl)-2-ind...) Show SMILES O=C(Cn1ccc2ccccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C17H17N3OS/c21-16(11-20-9-8-12-4-1-2-7-14(12)20)19-17-18-10-15(22-17)13-5-3-6-13/h1-2,4,7-10,13H,3,5-6,11H2,(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155213 (1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-8-yl-u...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2ccncc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)12-4-1-5-12)20-14-6-2-3-11-7-8-18-9-13(11)14/h2-3,6-10,12H,1,4-5H2,(H2,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155210 (CHEMBL426972 | N-(5-Isopropyl-thiazol-2-yl)-2-phen...) Show SMILES CC(C)c1cnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C14H16N2OS/c1-10(2)12-9-15-14(18-12)16-13(17)8-11-6-4-3-5-7-11/h3-7,9-10H,8H2,1-2H3,(H,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155206 (CHEMBL186511 | N-(5-Cyclopentyl-thiazol-2-yl)-2-ph...) Show SMILES O=C(Cc1ccccc1)Nc1ncc(s1)C1CCCC1 Show InChI InChI=1S/C16H18N2OS/c19-15(10-12-6-2-1-3-7-12)18-16-17-11-14(20-16)13-8-4-5-9-13/h1-3,6-7,11,13H,4-5,8-10H2,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155237 (CHEMBL184404 | N-(5-Cyclobutyl-thiazol-2-yl)-2-iso...) Show SMILES O=C(Cc1cccc2cnccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C18H17N3OS/c22-17(21-18-20-11-16(23-18)12-3-1-4-12)9-13-5-2-6-14-10-19-8-7-15(13)14/h2,5-8,10-12H,1,3-4,9H2,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155225 (CHEMBL365855 | N-(5-Cyclobutyl-thiazol-2-yl)-2-phe...) Show SMILES O=C(Cc1ccccc1)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C15H16N2OS/c18-14(9-11-5-2-1-3-6-11)17-15-16-10-13(19-15)12-7-4-8-12/h1-3,5-6,10,12H,4,7-9H2,(H,16,17,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155216 (CHEMBL185734 | N-(5-Methylsulfanyl-thiazol-2-yl)-2...) Show SMILES CSc1cnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C12H12N2OS2/c1-16-11-8-13-12(17-11)14-10(15)7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155209 (1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-5-yl-u...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2cnccc12 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-3-1-4-11)20-14-6-2-5-12-9-18-8-7-13(12)14/h2,5-11H,1,3-4H2,(H2,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155210 (CHEMBL426972 | N-(5-Isopropyl-thiazol-2-yl)-2-phen...) Show SMILES CC(C)c1cnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C14H16N2OS/c1-10(2)12-9-15-14(18-12)16-13(17)8-11-6-4-3-5-7-11/h3-7,9-10H,8H2,1-2H3,(H,15,16,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155220 (CHEMBL364338 | N-(5-Cyclobutyl-thiazol-2-yl)-2-ind...) Show SMILES O=C(Cn1ccc2ccccc12)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C17H17N3OS/c21-16(11-20-9-8-12-4-1-2-7-14(12)20)19-17-18-10-15(22-17)13-5-3-6-13/h1-2,4,7-10,13H,3,5-6,11H2,(H,18,19,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155234 (1-(5-Isopropyl-thiazol-2-yl)-3-phenyl-urea | CHEMB...) Show SMILES CC(C)c1cnc(NC(=O)Nc2ccccc2)s1 Show InChI InChI=1S/C13H15N3OS/c1-9(2)11-8-14-13(18-11)16-12(17)15-10-6-4-3-5-7-10/h3-9H,1-2H3,(H2,14,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155216 (CHEMBL185734 | N-(5-Methylsulfanyl-thiazol-2-yl)-2...) Show SMILES CSc1cnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C12H12N2OS2/c1-16-11-8-13-12(17-11)14-10(15)7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,13,14,15)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155232 (1-(3H-Benzotriazol-4-yl)-3-(5-cyclobutyl-thiazol-2...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2nn[nH]c12 Show InChI InChI=1S/C14H14N6OS/c21-13(16-9-5-2-6-10-12(9)19-20-18-10)17-14-15-7-11(22-14)8-3-1-4-8/h2,5-8H,1,3-4H2,(H,18,19,20)(H2,15,16,17,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155206 (CHEMBL186511 | N-(5-Cyclopentyl-thiazol-2-yl)-2-ph...) Show SMILES O=C(Cc1ccccc1)Nc1ncc(s1)C1CCCC1 Show InChI InChI=1S/C16H18N2OS/c19-15(10-12-6-2-1-3-7-12)18-16-17-11-14(20-16)13-8-4-5-9-13/h1-3,6-7,11,13H,4-5,8-10H2,(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155221 (1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-6-yl-urea...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1ccc2ncccc2c1 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-3-1-4-11)20-13-6-7-14-12(9-13)5-2-8-18-14/h2,5-11H,1,3-4H2,(H2,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155222 (1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-6-yl-u...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1ccc2cnccc2c1 Show InChI InChI=1S/C17H16N4OS/c22-16(21-17-19-10-15(23-17)11-2-1-3-11)20-14-5-4-13-9-18-7-6-12(13)8-14/h4-11H,1-3H2,(H2,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155211 (1-(5-Cyclobutyl-thiazol-2-yl)-3-phenyl-urea | CHEM...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1ccccc1 Show InChI InChI=1S/C14H15N3OS/c18-13(16-11-7-2-1-3-8-11)17-14-15-9-12(19-14)10-5-4-6-10/h1-3,7-10H,4-6H2,(H2,15,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155223 (1-(5-Cyclobutyl-thiazol-2-yl)-3-(1H-indazol-7-yl)-...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2c[nH]nc12 Show InChI InChI=1S/C15H15N5OS/c21-14(18-11-6-2-5-10-7-17-20-13(10)11)19-15-16-8-12(22-15)9-3-1-4-9/h2,5-9H,1,3-4H2,(H,17,20)(H2,16,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155234 (1-(5-Isopropyl-thiazol-2-yl)-3-phenyl-urea | CHEMB...) Show SMILES CC(C)c1cnc(NC(=O)Nc2ccccc2)s1 Show InChI InChI=1S/C13H15N3OS/c1-9(2)11-8-14-13(18-11)16-12(17)15-10-6-4-3-5-7-10/h3-9H,1-2H3,(H2,14,15,16,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155211 (1-(5-Cyclobutyl-thiazol-2-yl)-3-phenyl-urea | CHEM...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1ccccc1 Show InChI InChI=1S/C14H15N3OS/c18-13(16-11-7-2-1-3-8-11)17-14-15-9-12(19-14)10-5-4-6-10/h1-3,7-10H,4-6H2,(H2,15,16,17,18)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155212 (CHEMBL363711 | N-(5-Isopropyl-thiazol-2-yl)-isobut...) Show SMILES CC(C)C(=O)Nc1ncc(s1)C(C)C Show InChI InChI=1S/C10H16N2OS/c1-6(2)8-5-11-10(14-8)12-9(13)7(3)4/h5-7H,1-4H3,(H,11,12,13)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	318	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155212 (CHEMBL363711 | N-(5-Isopropyl-thiazol-2-yl)-isobut...) Show SMILES CC(C)C(=O)Nc1ncc(s1)C(C)C Show InChI InChI=1S/C10H16N2OS/c1-6(2)8-5-11-10(14-8)12-9(13)7(3)4/h5-7H,1-4H3,(H,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	321	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155228 (CHEMBL186846 | N-(5-Cyclohexyl-thiazol-2-yl)-2-phe...) Show SMILES O=C(Cc1ccccc1)Nc1ncc(s1)C1CCCCC1 Show InChI InChI=1S/C17H20N2OS/c20-16(11-13-7-3-1-4-8-13)19-17-18-12-15(21-17)14-9-5-2-6-10-14/h1,3-4,7-8,12,14H,2,5-6,9-11H2,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155226 (CHEMBL185498 | N-(5-Ethyl-thiazol-2-yl)-2-phenyl-a...) Show SMILES CCc1cnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C13H14N2OS/c1-2-11-9-14-13(17-11)15-12(16)8-10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3,(H,14,15,16)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	412	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155227 (CHEMBL186201 | N-(5-Bromo-thiazol-2-yl)-2-phenyl-a...) Show SMILES Brc1cnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C11H9BrN2OS/c12-9-7-13-11(16-9)14-10(15)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H,13,14,15)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155226 (CHEMBL185498 | N-(5-Ethyl-thiazol-2-yl)-2-phenyl-a...) Show SMILES CCc1cnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C13H14N2OS/c1-2-11-9-14-13(17-11)15-12(16)8-10-6-4-3-5-7-10/h3-7,9H,2,8H2,1H3,(H,14,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	621	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155223 (1-(5-Cyclobutyl-thiazol-2-yl)-3-(1H-indazol-7-yl)-...) Show SMILES O=C(Nc1ncc(s1)C1CCC1)Nc1cccc2c[nH]nc12 Show InChI InChI=1S/C15H15N5OS/c21-14(18-11-6-2-5-10-7-17-20-13(10)11)19-15-16-8-12(22-15)9-3-1-4-9/h2,5-9H,1,3-4H2,(H,17,20)(H2,16,18,19,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 (Homo sapiens (Human))	BDBM50155227 (CHEMBL186201 | N-(5-Bromo-thiazol-2-yl)-2-phenyl-a...) Show SMILES Brc1cnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C11H9BrN2OS/c12-9-7-13-11(16-9)14-10(15)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155208 ((5-Isopropyl-thiazol-2-yl)-carbamic acid phenyl es...) Show SMILES CC(C)c1cnc(NC(=O)Oc2ccccc2)s1 Show InChI InChI=1S/C13H14N2O2S/c1-9(2)11-8-14-12(18-11)15-13(16)17-10-6-4-3-5-7-10/h3-9H,1-2H3,(H,14,15,16)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155228 (CHEMBL186846 | N-(5-Cyclohexyl-thiazol-2-yl)-2-phe...) Show SMILES O=C(Cc1ccccc1)Nc1ncc(s1)C1CCCCC1 Show InChI InChI=1S/C17H20N2OS/c20-16(11-13-7-3-1-4-8-13)19-17-18-12-15(21-17)14-9-5-2-6-10-14/h1,3-4,7-8,12,14H,2,5-6,9-11H2,(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	997	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50155233 (CHEMBL188172 | N-(5-Isopropyl-thiazol-2-yl)-benzam...) Show SMILES CC(C)c1cnc(NC(=O)c2ccccc2)s1 Show InChI InChI=1S/C13H14N2OS/c1-9(2)11-8-14-13(17-11)15-12(16)10-6-4-3-5-7-10/h3-9H,1-2H3,(H,14,15,16)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assay				Bioorg Med Chem Lett 14: 5521-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.006 BindingDB Entry DOI: 10.7270/Q2D50MFB
					More data for this Ligand-Target Pair

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