Compile Data Set for Download or QSAR

Found 60 hits Enz. Inhib. hit(s) with all data for entry = 50047559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174739 (CHEMBL3808906) Show SMILES CCCCN(C1CCN(CC1)c1ncnc2sc(C)c(C)c12)c1ccc(C)nc1 Show InChI InChI=1S/C23H31N5S/c1-5-6-11-28(20-8-7-16(2)24-14-20)19-9-12-27(13-10-19)22-21-17(3)18(4)29-23(21)26-15-25-22/h7-8,14-15,19H,5-6,9-13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174738 (CHEMBL3808947) Show SMILES CCCN(C1CCN(CC1)c1ncnc2sc(C)c(C)c12)c1ccc(C)nc1 Show InChI InChI=1S/C22H29N5S/c1-5-10-27(19-7-6-15(2)23-13-19)18-8-11-26(12-9-18)21-20-16(3)17(4)28-22(20)25-14-24-21/h6-7,13-14,18H,5,8-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50174737 (CHEMBL1357034) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)S(N)(=O)=O)c2c1C Show InChI InChI=1S/C20H23N5O3S2/c1-12-13(2)29-20-17(12)18(22-11-23-20)25-9-7-14(8-10-25)19(26)24-15-3-5-16(6-4-15)30(21,27)28/h3-6,11,14H,7-10H2,1-2H3,(H,24,26)(H2,21,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of CYP2D6 (unknown origin)				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50174737 (CHEMBL1357034) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)S(N)(=O)=O)c2c1C Show InChI InChI=1S/C20H23N5O3S2/c1-12-13(2)29-20-17(12)18(22-11-23-20)25-9-7-14(8-10-25)19(26)24-15-3-5-16(6-4-15)30(21,27)28/h3-6,11,14H,7-10H2,1-2H3,(H,24,26)(H2,21,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of CYP2C9 (unknown origin)				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50174737 (CHEMBL1357034) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)S(N)(=O)=O)c2c1C Show InChI InChI=1S/C20H23N5O3S2/c1-12-13(2)29-20-17(12)18(22-11-23-20)25-9-7-14(8-10-25)19(26)24-15-3-5-16(6-4-15)30(21,27)28/h3-6,11,14H,7-10H2,1-2H3,(H,24,26)(H2,21,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin)				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50174737 (CHEMBL1357034) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)S(N)(=O)=O)c2c1C Show InChI InChI=1S/C20H23N5O3S2/c1-12-13(2)29-20-17(12)18(22-11-23-20)25-9-7-14(8-10-25)19(26)24-15-3-5-16(6-4-15)30(21,27)28/h3-6,11,14H,7-10H2,1-2H3,(H,24,26)(H2,21,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of CYP1A2 (unknown origin)				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174723 (CHEMBL1314270) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3cc(Cl)ccc3Cl)c2c1C Show InChI InChI=1S/C20H20Cl2N4OS/c1-11-12(2)28-20-17(11)18(23-10-24-20)26-7-5-13(6-8-26)19(27)25-16-9-14(21)3-4-15(16)22/h3-4,9-10,13H,5-8H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174724 (CHEMBL3809603) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCCC3)c2c1C Show InChI InChI=1S/C18H24N4OS/c1-12-13(2)24-17-15(12)16(19-11-20-17)21-9-5-14(6-10-21)18(23)22-7-3-4-8-22/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174725 (CHEMBL3808983) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CC[C@H](F)C3)c2c1C |r| Show InChI InChI=1S/C18H23FN4OS/c1-11-12(2)25-17-15(11)16(20-10-21-17)22-6-3-13(4-7-22)18(24)23-8-5-14(19)9-23/h10,13-14H,3-9H2,1-2H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	970	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174726 (CHEMBL3808696) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCCC(F)(F)C3)c2c1C Show InChI InChI=1S/C19H24F2N4OS/c1-12-13(2)27-17-15(12)16(22-11-23-17)24-8-4-14(5-9-24)18(26)25-7-3-6-19(20,21)10-25/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174727 (CHEMBL3808425) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCOCC3)c2c1C Show InChI InChI=1S/C18H24N4O2S/c1-12-13(2)25-17-15(12)16(19-11-20-17)21-5-3-14(4-6-21)18(23)22-7-9-24-10-8-22/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174728 (CHEMBL3809482) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCSCC3)c2c1C Show InChI InChI=1S/C18H24N4OS2/c1-12-13(2)25-17-15(12)16(19-11-20-17)21-5-3-14(4-6-21)18(23)22-7-9-24-10-8-22/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	820	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174729 (CHEMBL3809378) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCCc4cc(ccc34)S(C)(=O)=O)c2c1C Show InChI InChI=1S/C24H28N4O3S2/c1-15-16(2)32-23-21(15)22(25-14-26-23)27-11-8-17(9-12-27)24(29)28-10-4-5-18-13-19(33(3,30)31)6-7-20(18)28/h6-7,13-14,17H,4-5,8-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	960	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174730 (CHEMBL3808442) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3cnc(C)nc3)c2c1C Show InChI InChI=1S/C18H21N5OS/c1-11-12(2)25-18-16(11)17(21-10-22-18)23-6-4-14(5-7-23)24-15-8-19-13(3)20-9-15/h8-10,14H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174731 (CHEMBL3809096) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3ccc(C)nc3)c2c1C Show InChI InChI=1S/C19H22N4OS/c1-12-4-5-16(10-20-12)24-15-6-8-23(9-7-15)18-17-13(2)14(3)25-19(17)22-11-21-18/h4-5,10-11,15H,6-9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174732 (CHEMBL3809693) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3ccc(F)nc3)c2c1C Show InChI InChI=1S/C18H19FN4OS/c1-11-12(2)25-18-16(11)17(21-10-22-18)23-7-5-13(6-8-23)24-14-3-4-15(19)20-9-14/h3-4,9-10,13H,5-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174733 (CHEMBL3810183) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3ccc(Cl)nc3)c2c1C Show InChI InChI=1S/C18H19ClN4OS/c1-11-12(2)25-18-16(11)17(21-10-22-18)23-7-5-13(6-8-23)24-14-3-4-15(19)20-9-14/h3-4,9-10,13H,5-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174734 (CHEMBL3810300) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3ccc4OCCc4c3)c2c1C Show InChI InChI=1S/C21H23N3O2S/c1-13-14(2)27-21-19(13)20(22-12-23-21)24-8-5-16(6-9-24)26-17-3-4-18-15(11-17)7-10-25-18/h3-4,11-12,16H,5-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174735 (CHEMBL3809292) Show SMILES Cc1ccc2ncnc(N3CCC(CC3)Oc3ccc(C)nc3)c2c1 Show InChI InChI=1S/C20H22N4O/c1-14-3-6-19-18(11-14)20(23-13-22-19)24-9-7-16(8-10-24)25-17-5-4-15(2)21-12-17/h3-6,11-13,16H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174736 (CHEMBL3808485) Show SMILES Cc1ccc(OC2CCN(CC2)c2ncnc3ccc(F)cc23)cn1 Show InChI InChI=1S/C19H19FN4O/c1-13-2-4-16(11-21-13)25-15-6-8-24(9-7-15)19-17-10-14(20)3-5-18(17)22-12-23-19/h2-5,10-12,15H,6-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174740 (CHEMBL3810215) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(N)=O)c2c1C Show InChI InChI=1S/C14H18N4OS/c1-8-9(2)20-14-11(8)13(16-7-17-14)18-5-3-10(4-6-18)12(15)19/h7,10H,3-6H2,1-2H3,(H2,15,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50174736 (CHEMBL3808485) Show SMILES Cc1ccc(OC2CCN(CC2)c2ncnc3ccc(F)cc23)cn1 Show InChI InChI=1S/C19H19FN4O/c1-13-2-4-16(11-21-13)25-15-6-8-24(9-7-15)19-17-10-14(20)3-5-18(17)22-12-23-19/h2-5,10-12,15H,6-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M3				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50174736 (CHEMBL3808485) Show SMILES Cc1ccc(OC2CCN(CC2)c2ncnc3ccc(F)cc23)cn1 Show InChI InChI=1S/C19H19FN4O/c1-13-2-4-16(11-21-13)25-15-6-8-24(9-7-15)19-17-10-14(20)3-5-18(17)22-12-23-19/h2-5,10-12,15H,6-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M2				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50174736 (CHEMBL3808485) Show SMILES Cc1ccc(OC2CCN(CC2)c2ncnc3ccc(F)cc23)cn1 Show InChI InChI=1S/C19H19FN4O/c1-13-2-4-16(11-21-13)25-15-6-8-24(9-7-15)19-17-10-14(20)3-5-18(17)22-12-23-19/h2-5,10-12,15H,6-9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M5 receptor expressed in CHOK1 cells by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50174736 (CHEMBL3808485) Show SMILES Cc1ccc(OC2CCN(CC2)c2ncnc3ccc(F)cc23)cn1 Show InChI InChI=1S/C19H19FN4O/c1-13-2-4-16(11-21-13)25-15-6-8-24(9-7-15)19-17-10-14(20)3-5-18(17)22-12-23-19/h2-5,10-12,15H,6-9H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M1 receptor expressed in CHOK1 cells by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174741 (CHEMBL3809076) Show SMILES Cc1ccc(OC2CCN(CC2)c2cc(C)nc3ccc(F)cc23)cn1 Show InChI InChI=1S/C21H22FN3O/c1-14-3-5-18(13-23-14)26-17-7-9-25(10-8-17)21-11-15(2)24-20-6-4-16(22)12-19(20)21/h3-6,11-13,17H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174742 (CHEMBL3810071) Show SMILES Cc1ccn2nc(C)nc(N3CCC(CC3)Oc3ccc(C)nc3)c12 Show InChI InChI=1S/C19H23N5O/c1-13-6-11-24-18(13)19(21-15(3)22-24)23-9-7-16(8-10-23)25-17-5-4-14(2)20-12-17/h4-6,11-12,16H,7-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174737 (CHEMBL1357034) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)S(N)(=O)=O)c2c1C Show InChI InChI=1S/C20H23N5O3S2/c1-12-13(2)29-20-17(12)18(22-11-23-20)25-9-7-14(8-10-25)19(26)24-15-3-5-16(6-4-15)30(21,27)28/h3-6,11,14H,7-10H2,1-2H3,(H,24,26)(H2,21,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174740 (CHEMBL3810215) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(N)=O)c2c1C Show InChI InChI=1S/C14H18N4OS/c1-8-9(2)20-14-11(8)13(16-7-17-14)18-5-3-10(4-6-18)12(15)19/h7,10H,3-6H2,1-2H3,(H2,15,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174585 (CHEMBL3809384) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)NCc3ccc(cc3)S(N)(=O)=O)c2c1C Show InChI InChI=1S/C21H25N5O3S2/c1-13-14(2)30-21-18(13)19(24-12-25-21)26-9-7-16(8-10-26)20(27)23-11-15-3-5-17(6-4-15)31(22,28)29/h3-6,12,16H,7-11H2,1-2H3,(H,23,27)(H2,22,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174586 (CHEMBL3808920) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)C(N)=O)c2c1C Show InChI InChI=1S/C21H23N5O2S/c1-12-13(2)29-21-17(12)19(23-11-24-21)26-9-7-15(8-10-26)20(28)25-16-5-3-14(4-6-16)18(22)27/h3-6,11,15H,7-10H2,1-2H3,(H2,22,27)(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	389	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174587 (CHEMBL1455259) Show SMILES CNC(=O)c1ccc(NC(=O)C2CCN(CC2)c2ncnc3sc(C)c(C)c23)cc1 Show InChI InChI=1S/C22H25N5O2S/c1-13-14(2)30-22-18(13)19(24-12-25-22)27-10-8-16(9-11-27)21(29)26-17-6-4-15(5-7-17)20(28)23-3/h4-7,12,16H,8-11H2,1-3H3,(H,23,28)(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	575	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174588 (CHEMBL3808592) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)S(C)(=O)=O)c2c1C Show InChI InChI=1S/C21H24N4O3S2/c1-13-14(2)29-21-18(13)19(22-12-23-21)25-10-8-15(9-11-25)20(26)24-16-4-6-17(7-5-16)30(3,27)28/h4-7,12,15H,8-11H2,1-3H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	851	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174589 (CHEMBL3808847) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(cc3)N3CCNC3=O)c2c1C Show InChI InChI=1S/C23H26N6O2S/c1-14-15(2)32-22-19(14)20(25-13-26-22)28-10-7-16(8-11-28)21(30)27-17-3-5-18(6-4-17)29-12-9-24-23(29)31/h3-6,13,16H,7-12H2,1-2H3,(H,24,31)(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.17E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174590 (CHEMBL1603219) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3ccc(F)cc3Cl)c2c1C Show InChI InChI=1S/C20H20ClFN4OS/c1-11-12(2)28-20-17(11)18(23-10-24-20)26-7-5-13(6-8-26)19(27)25-16-4-3-14(22)9-15(16)21/h3-4,9-10,13H,5-8H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174723 (CHEMBL1314270) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)Nc3cc(Cl)ccc3Cl)c2c1C Show InChI InChI=1S/C20H20Cl2N4OS/c1-11-12(2)28-20-17(11)18(23-10-24-20)26-7-5-13(6-8-26)19(27)25-16-9-14(21)3-4-15(16)22/h3-4,9-10,13H,5-8H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174724 (CHEMBL3809603) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCCC3)c2c1C Show InChI InChI=1S/C18H24N4OS/c1-12-13(2)24-17-15(12)16(19-11-20-17)21-9-5-14(6-10-21)18(23)22-7-3-4-8-22/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174725 (CHEMBL3808983) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CC[C@H](F)C3)c2c1C |r| Show InChI InChI=1S/C18H23FN4OS/c1-11-12(2)25-17-15(11)16(20-10-21-17)22-6-3-13(4-7-22)18(24)23-8-5-14(19)9-23/h10,13-14H,3-9H2,1-2H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	977	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174726 (CHEMBL3808696) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCCC(F)(F)C3)c2c1C Show InChI InChI=1S/C19H24F2N4OS/c1-12-13(2)27-17-15(12)16(22-11-23-17)24-8-4-14(5-9-24)18(26)25-7-3-6-19(20,21)10-25/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174727 (CHEMBL3808425) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCOCC3)c2c1C Show InChI InChI=1S/C18H24N4O2S/c1-12-13(2)25-17-15(12)16(19-11-20-17)21-5-3-14(4-6-21)18(23)22-7-9-24-10-8-22/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174728 (CHEMBL3809482) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCSCC3)c2c1C Show InChI InChI=1S/C18H24N4OS2/c1-12-13(2)25-17-15(12)16(19-11-20-17)21-5-3-14(4-6-21)18(23)22-7-9-24-10-8-22/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	813	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174729 (CHEMBL3809378) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCCc4cc(ccc34)S(C)(=O)=O)c2c1C Show InChI InChI=1S/C24H28N4O3S2/c1-15-16(2)32-23-21(15)22(25-14-26-23)27-11-8-17(9-12-27)24(29)28-10-4-5-18-13-19(33(3,30)31)6-7-20(18)28/h6-7,13-14,17H,4-5,8-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	955	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174730 (CHEMBL3808442) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3cnc(C)nc3)c2c1C Show InChI InChI=1S/C18H21N5OS/c1-11-12(2)25-18-16(11)17(21-10-22-18)23-6-4-14(5-7-23)24-15-8-19-13(3)20-9-15/h8-10,14H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174731 (CHEMBL3809096) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3ccc(C)nc3)c2c1C Show InChI InChI=1S/C19H22N4OS/c1-12-4-5-16(10-20-12)24-15-6-8-23(9-7-15)18-17-13(2)14(3)25-19(17)22-11-21-18/h4-5,10-11,15H,6-9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	603	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174732 (CHEMBL3809693) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3ccc(F)nc3)c2c1C Show InChI InChI=1S/C18H19FN4OS/c1-11-12(2)25-18-16(11)17(21-10-22-18)23-7-5-13(6-8-23)24-14-3-4-15(19)20-9-14/h3-4,9-10,13H,5-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174733 (CHEMBL3810183) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3ccc(Cl)nc3)c2c1C Show InChI InChI=1S/C18H19ClN4OS/c1-11-12(2)25-18-16(11)17(21-10-22-18)23-7-5-13(6-8-23)24-14-3-4-15(19)20-9-14/h3-4,9-10,13H,5-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174734 (CHEMBL3810300) Show SMILES Cc1sc2ncnc(N3CCC(CC3)Oc3ccc4OCCc4c3)c2c1C Show InChI InChI=1S/C21H23N3O2S/c1-13-14(2)27-21-19(13)20(22-12-23-21)24-8-5-16(6-9-24)26-17-3-4-18-15(11-17)7-10-25-18/h3-4,11-12,16H,5-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174735 (CHEMBL3809292) Show SMILES Cc1ccc2ncnc(N3CCC(CC3)Oc3ccc(C)nc3)c2c1 Show InChI InChI=1S/C20H22N4O/c1-14-3-6-19-18(11-14)20(23-13-22-19)24-9-7-16(8-10-24)25-17-5-4-15(2)21-12-17/h3-6,11-13,16H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174736 (CHEMBL3808485) Show SMILES Cc1ccc(OC2CCN(CC2)c2ncnc3ccc(F)cc23)cn1 Show InChI InChI=1S/C19H19FN4O/c1-13-2-4-16(11-21-13)25-15-6-8-24(9-7-15)19-17-10-14(20)3-5-18(17)22-12-23-19/h2-5,10-12,15H,6-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	575	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174741 (CHEMBL3809076) Show SMILES Cc1ccc(OC2CCN(CC2)c2cc(C)nc3ccc(F)cc23)cn1 Show InChI InChI=1S/C21H22FN3O/c1-14-3-5-18(13-23-14)26-17-7-9-25(10-8-17)21-11-15(2)24-20-6-4-16(22)12-19(20)21/h3-6,11-13,17H,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	692	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 60 total )  |  Next  |  Last  >>

Jump to: