Found 72 hits Enz. Inhib. hit(s) with all data for entry = 50030272 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293496
(2-(3-((N-(4-tert-butylbenzyl)pyridine-3-sulfonamid...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(OCC(O)=O)c2)S(=O)(=O)c2cccnc2)cc1 Show InChI InChI=1S/C25H28N2O5S/c1-25(2,3)21-11-9-19(10-12-21)16-27(33(30,31)23-8-5-13-26-15-23)17-20-6-4-7-22(14-20)32-18-24(28)29/h4-15H,16-18H2,1-3H3,(H,28,29) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293493
(3-(3-((N-(4-tert-butylbenzyl)pyridine-2-sulfonamid...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C26H30N2O4S/c1-26(2,3)23-13-10-21(11-14-23)18-28(33(31,32)24-9-4-5-16-27-24)19-22-8-6-7-20(17-22)12-15-25(29)30/h4-11,13-14,16-17H,12,15,18-19H2,1-3H3,(H,29,30) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293495
(3-(3-((N-(4-tert-butylbenzyl)thiazole-2-sulfonamid...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(=O)(=O)c2nccs2)cc1 Show InChI InChI=1S/C24H28N2O4S2/c1-24(2,3)21-10-7-19(8-11-21)16-26(32(29,30)23-25-13-14-31-23)17-20-6-4-5-18(15-20)9-12-22(27)28/h4-8,10-11,13-15H,9,12,16-17H2,1-3H3,(H,27,28) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293498
(7-(N-(4-(1-hydroxyhexyl)benzyl)methylsulfonamido)h...)Show SMILES CCCCCC(O)c1ccc(CN(CCCCCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H35NO5S/c1-3-4-7-10-20(23)19-14-12-18(13-15-19)17-22(28(2,26)27)16-9-6-5-8-11-21(24)25/h12-15,20,23H,3-11,16-17H2,1-2H3,(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293502
(7-(N-(4-butylbenzyl)methylsulfonamido)heptanoic ac...)Show InChI InChI=1S/C19H31NO4S/c1-3-4-9-17-11-13-18(14-12-17)16-20(25(2,23)24)15-8-6-5-7-10-19(21)22/h11-14H,3-10,15-16H2,1-2H3,(H,21,22) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293497
(7-(N-(4-hydroxynonyl)methylsulfonamido)heptanoic a...)Show InChI InChI=1S/C17H35NO5S/c1-3-4-7-11-16(19)12-10-15-18(24(2,22)23)14-9-6-5-8-13-17(20)21/h16,19H,3-15H2,1-2H3,(H,20,21) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293490
(3-(3-((N-(4-butylbenzyl)methylsulfonamido)methyl)p...)Show SMILES CCCCc1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-3-4-6-18-9-11-20(12-10-18)16-23(28(2,26)27)17-21-8-5-7-19(15-21)13-14-22(24)25/h5,7-12,15H,3-4,6,13-14,16-17H2,1-2H3,(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293492
(3-(3-((N-(4-tert-butylbenzyl)phenylsulfonamido)met...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H31NO4S/c1-27(2,3)24-15-12-22(13-16-24)19-28(33(31,32)25-10-5-4-6-11-25)20-23-9-7-8-21(18-23)14-17-26(29)30/h4-13,15-16,18H,14,17,19-20H2,1-3H3,(H,29,30) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 278 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293503
(7-(N-(biphenyl-4-ylmethyl)methylsulfonamido)heptan...)Show SMILES CS(=O)(=O)N(CCCCCCC(O)=O)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H27NO4S/c1-27(25,26)22(16-8-3-2-7-11-21(23)24)17-18-12-14-20(15-13-18)19-9-5-4-6-10-19/h4-6,9-10,12-15H,2-3,7-8,11,16-17H2,1H3,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 289 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293494
(2-(3-((N-(4-tert-butylbenzyl)-1-(1-methyl-1H-imida...)Show SMILES Cn1ccnc1CS(=O)(=O)N(Cc1ccc(cc1)C(C)(C)C)Cc1cccc(OCC(O)=O)c1 Show InChI InChI=1S/C25H31N3O5S/c1-25(2,3)21-10-8-19(9-11-21)15-28(34(31,32)18-23-26-12-13-27(23)4)16-20-6-5-7-22(14-20)33-17-24(29)30/h5-14H,15-18H2,1-4H3,(H,29,30) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 326 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293491
(3-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-22(2,3)20-11-8-18(9-12-20)15-23(28(4,26)27)16-19-7-5-6-17(14-19)10-13-21(24)25/h5-9,11-12,14H,10,13,15-16H2,1-4H3,(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 379 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293509
(4-(2-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)Show SMILES CCCCc1ccc(CN(c2ccccc2CCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-3-4-8-18-13-15-19(16-14-18)17-23(28(2,26)27)21-11-6-5-9-20(21)10-7-12-22(24)25/h5-6,9,11,13-16H,3-4,7-8,10,12,17H2,1-2H3,(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 494 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293501
(7-(N-(4-(1-hydroxypentyl)benzyl)methylsulfonamido)...)Show SMILES CCCCC(O)c1ccc(CN(CCCCCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H33NO5S/c1-3-4-9-19(22)18-13-11-17(12-14-18)16-21(27(2,25)26)15-8-6-5-7-10-20(23)24/h11-14,19,22H,3-10,15-16H2,1-2H3,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 502 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293504
(7-(N-(4-tert-butylbenzyl)methylsulfonamido)heptano...)Show SMILES CC(C)(C)c1ccc(CN(CCCCCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H31NO4S/c1-19(2,3)17-12-10-16(11-13-17)15-20(25(4,23)24)14-8-6-5-7-9-18(21)22/h10-13H,5-9,14-15H2,1-4H3,(H,21,22) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293500
(7-(N-(4-hexanoylbenzyl)methylsulfonamido)heptanoic...)Show SMILES CCCCCC(=O)c1ccc(CN(CCCCCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H33NO5S/c1-3-4-7-10-20(23)19-14-12-18(13-15-19)17-22(28(2,26)27)16-9-6-5-8-11-21(24)25/h12-15H,3-11,16-17H2,1-2H3,(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 636 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293510
(4-(4-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)Show SMILES CCCCc1ccc(CN(c2ccc(CCCC(O)=O)cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-3-4-6-18-9-11-20(12-10-18)17-23(28(2,26)27)21-15-13-19(14-16-21)7-5-8-22(24)25/h9-16H,3-8,17H2,1-2H3,(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 654 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293505
(2-(4-(N-(4-butylbenzyl)methylsulfonamido)butoxy)ac...)Show InChI InChI=1S/C18H29NO5S/c1-3-4-7-16-8-10-17(11-9-16)14-19(25(2,22)23)12-5-6-13-24-15-18(20)21/h8-11H,3-7,12-15H2,1-2H3,(H,20,21) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 701 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293489
(2-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(OCC(O)=O)c2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H27NO5S/c1-21(2,3)18-10-8-16(9-11-18)13-22(28(4,25)26)14-17-6-5-7-19(12-17)27-15-20(23)24/h5-12H,13-15H2,1-4H3,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 792 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293507
(2-(4-(2-(N-(4-butylbenzyl)methylsulfonamido)ethyl)...)Show SMILES CCCCc1ccc(CN(CCc2ccc(CC(O)=O)cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-3-4-5-18-8-12-21(13-9-18)17-23(28(2,26)27)15-14-19-6-10-20(11-7-19)16-22(24)25/h6-13H,3-5,14-17H2,1-2H3,(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 833 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293488
(6-(N-(4-hydroxynonyl)methylsulfonamido)hexanoic ac...)Show InChI InChI=1S/C16H33NO5S/c1-3-4-6-10-15(18)11-9-14-17(23(2,21)22)13-8-5-7-12-16(19)20/h15,18H,3-14H2,1-2H3,(H,19,20) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293504
(7-(N-(4-tert-butylbenzyl)methylsulfonamido)heptano...)Show SMILES CC(C)(C)c1ccc(CN(CCCCCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H31NO4S/c1-19(2,3)17-12-10-16(11-13-17)15-20(25(4,23)24)14-8-6-5-7-9-18(21)22/h10-13H,5-9,14-15H2,1-4H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293499
(7-(N-(4-hydroxy-6-methylheptyl)methylsulfonamido)h...)Show InChI InChI=1S/C16H33NO5S/c1-14(2)13-15(18)9-8-12-17(23(3,21)22)11-7-5-4-6-10-16(19)20/h14-15,18H,4-13H2,1-3H3,(H,19,20) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293497
(7-(N-(4-hydroxynonyl)methylsulfonamido)heptanoic a...)Show InChI InChI=1S/C17H35NO5S/c1-3-4-7-11-16(19)12-10-15-18(24(2,22)23)14-9-6-5-8-13-17(20)21/h16,19H,3-15H2,1-2H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293506
(3-(3-(N-(4-butylbenzyl)methylsulfonamido)propoxy)b...)Show SMILES CCCCc1ccc(CN(CCCOc2cccc(c2)C(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO5S/c1-3-4-7-18-10-12-19(13-11-18)17-23(29(2,26)27)14-6-15-28-21-9-5-8-20(16-21)22(24)25/h5,8-13,16H,3-4,6-7,14-15,17H2,1-2H3,(H,24,25) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293498
(7-(N-(4-(1-hydroxyhexyl)benzyl)methylsulfonamido)h...)Show SMILES CCCCCC(O)c1ccc(CN(CCCCCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H35NO5S/c1-3-4-7-10-20(23)19-14-12-18(13-15-19)17-22(28(2,26)27)16-9-6-5-8-11-21(24)25/h12-15,20,23H,3-11,16-17H2,1-2H3,(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293499
(7-(N-(4-hydroxy-6-methylheptyl)methylsulfonamido)h...)Show InChI InChI=1S/C16H33NO5S/c1-14(2)13-15(18)9-8-12-17(23(3,21)22)11-7-5-4-6-10-16(19)20/h14-15,18H,4-13H2,1-3H3,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293500
(7-(N-(4-hexanoylbenzyl)methylsulfonamido)heptanoic...)Show SMILES CCCCCC(=O)c1ccc(CN(CCCCCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H33NO5S/c1-3-4-7-10-20(23)19-14-12-18(13-15-19)17-22(28(2,26)27)16-9-6-5-8-11-21(24)25/h12-15H,3-11,16-17H2,1-2H3,(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293501
(7-(N-(4-(1-hydroxypentyl)benzyl)methylsulfonamido)...)Show SMILES CCCCC(O)c1ccc(CN(CCCCCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H33NO5S/c1-3-4-9-19(22)18-13-11-17(12-14-18)16-21(27(2,25)26)15-8-6-5-7-10-20(23)24/h11-14,19,22H,3-10,15-16H2,1-2H3,(H,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293502
(7-(N-(4-butylbenzyl)methylsulfonamido)heptanoic ac...)Show InChI InChI=1S/C19H31NO4S/c1-3-4-9-17-11-13-18(14-12-17)16-20(25(2,23)24)15-8-6-5-7-10-19(21)22/h11-14H,3-10,15-16H2,1-2H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293503
(7-(N-(biphenyl-4-ylmethyl)methylsulfonamido)heptan...)Show SMILES CS(=O)(=O)N(CCCCCCC(O)=O)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H27NO4S/c1-27(25,26)22(16-8-3-2-7-11-21(23)24)17-18-12-14-20(15-13-18)19-9-5-4-6-10-19/h4-6,9-10,12-15H,2-3,7-8,11,16-17H2,1H3,(H,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293511
(3-(3-(N-(4-butylbenzyl)methylsulfonamido)phenyl)pr...)Show SMILES CCCCc1ccc(CN(c2cccc(CCC(O)=O)c2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H27NO4S/c1-3-4-6-17-9-11-19(12-10-17)16-22(27(2,25)26)20-8-5-7-18(15-20)13-14-21(23)24/h5,7-12,15H,3-4,6,13-14,16H2,1-2H3,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293506
(3-(3-(N-(4-butylbenzyl)methylsulfonamido)propoxy)b...)Show SMILES CCCCc1ccc(CN(CCCOc2cccc(c2)C(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO5S/c1-3-4-7-18-10-12-19(13-11-18)17-23(29(2,26)27)14-6-15-28-21-9-5-8-20(16-21)22(24)25/h5,8-13,16H,3-4,6-7,14-15,17H2,1-2H3,(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293507
(2-(4-(2-(N-(4-butylbenzyl)methylsulfonamido)ethyl)...)Show SMILES CCCCc1ccc(CN(CCc2ccc(CC(O)=O)cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-3-4-5-18-8-12-21(13-9-18)17-23(28(2,26)27)15-14-19-6-10-20(11-7-19)16-22(24)25/h6-13H,3-5,14-17H2,1-2H3,(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293508
(2-(2-((N-(4-butylbenzyl)methylsulfonamido)methyl)p...)Show SMILES CCCCc1ccc(CN(Cc2ccccc2OCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H27NO5S/c1-3-4-7-17-10-12-18(13-11-17)14-22(28(2,25)26)15-19-8-5-6-9-20(19)27-16-21(23)24/h5-6,8-13H,3-4,7,14-16H2,1-2H3,(H,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293509
(4-(2-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)Show SMILES CCCCc1ccc(CN(c2ccccc2CCCC(O)=O)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-3-4-8-18-13-15-19(16-14-18)17-23(28(2,26)27)21-11-6-5-9-20(21)10-7-12-22(24)25/h5-6,9,11,13-16H,3-4,7-8,10,12,17H2,1-2H3,(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293510
(4-(4-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)Show SMILES CCCCc1ccc(CN(c2ccc(CCCC(O)=O)cc2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-3-4-6-18-9-11-20(12-10-18)17-23(28(2,26)27)21-15-13-19(14-16-21)7-5-8-22(24)25/h9-16H,3-8,17H2,1-2H3,(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293511
(3-(3-(N-(4-butylbenzyl)methylsulfonamido)phenyl)pr...)Show SMILES CCCCc1ccc(CN(c2cccc(CCC(O)=O)c2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H27NO4S/c1-3-4-6-17-9-11-19(12-10-17)16-22(27(2,25)26)20-8-5-7-18(15-20)13-14-21(23)24/h5,7-12,15H,3-4,6,13-14,16H2,1-2H3,(H,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293489
(2-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(OCC(O)=O)c2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C21H27NO5S/c1-21(2,3)18-10-8-16(9-11-18)13-22(28(4,25)26)14-17-6-5-7-19(12-17)27-15-20(23)24/h5-12H,13-15H2,1-4H3,(H,23,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293490
(3-(3-((N-(4-butylbenzyl)methylsulfonamido)methyl)p...)Show SMILES CCCCc1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-3-4-6-18-9-11-20(12-10-18)16-23(28(2,26)27)17-21-8-5-7-19(15-21)13-14-22(24)25/h5,7-12,15H,3-4,6,13-14,16-17H2,1-2H3,(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293491
(3-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-22(2,3)20-11-8-18(9-12-20)15-23(28(4,26)27)16-19-7-5-6-17(14-19)10-13-21(24)25/h5-9,11-12,14H,10,13,15-16H2,1-4H3,(H,24,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293492
(3-(3-((N-(4-tert-butylbenzyl)phenylsulfonamido)met...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H31NO4S/c1-27(2,3)24-15-12-22(13-16-24)19-28(33(31,32)25-10-5-4-6-11-25)20-23-9-7-8-21(18-23)14-17-26(29)30/h4-13,15-16,18H,14,17,19-20H2,1-3H3,(H,29,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293493
(3-(3-((N-(4-tert-butylbenzyl)pyridine-2-sulfonamid...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(=O)(=O)c2ccccn2)cc1 Show InChI InChI=1S/C26H30N2O4S/c1-26(2,3)23-13-10-21(11-14-23)18-28(33(31,32)24-9-4-5-16-27-24)19-22-8-6-7-20(17-22)12-15-25(29)30/h4-11,13-14,16-17H,12,15,18-19H2,1-3H3,(H,29,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293494
(2-(3-((N-(4-tert-butylbenzyl)-1-(1-methyl-1H-imida...)Show SMILES Cn1ccnc1CS(=O)(=O)N(Cc1ccc(cc1)C(C)(C)C)Cc1cccc(OCC(O)=O)c1 Show InChI InChI=1S/C25H31N3O5S/c1-25(2,3)21-10-8-19(9-11-21)15-28(34(31,32)18-23-26-12-13-27(23)4)16-20-6-5-7-22(14-20)33-17-24(29)30/h5-14H,15-18H2,1-4H3,(H,29,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293512
(3-(3-((N-(4-tert-butylbenzyl)-4-chlorophenylsulfon...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(=O)(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C27H30ClNO4S/c1-27(2,3)23-10-7-21(8-11-23)18-29(34(32,33)25-14-12-24(28)13-15-25)19-22-6-4-5-20(17-22)9-16-26(30)31/h4-8,10-15,17H,9,16,18-19H2,1-3H3,(H,30,31) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293495
(3-(3-((N-(4-tert-butylbenzyl)thiazole-2-sulfonamid...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(=O)(=O)c2nccs2)cc1 Show InChI InChI=1S/C24H28N2O4S2/c1-24(2,3)21-10-7-19(8-11-21)16-26(32(29,30)23-25-13-14-31-23)17-20-6-4-5-18(15-20)9-12-22(27)28/h4-8,10-11,13-15H,9,12,16-17H2,1-3H3,(H,27,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293487
(5-(N-(4-hydroxynonyl)methylsulfonamido)pentanoic a...)Show InChI InChI=1S/C15H31NO5S/c1-3-4-5-9-14(17)10-8-13-16(22(2,20)21)12-7-6-11-15(18)19/h14,17H,3-13H2,1-2H3,(H,18,19) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Rattus norvegicus) | BDBM50293496
(2-(3-((N-(4-tert-butylbenzyl)pyridine-3-sulfonamid...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(OCC(O)=O)c2)S(=O)(=O)c2cccnc2)cc1 Show InChI InChI=1S/C25H28N2O5S/c1-25(2,3)21-11-9-19(10-12-21)16-27(33(30,31)23-8-5-13-26-15-23)17-20-6-4-7-22(14-20)32-18-24(28)29/h4-15H,16-18H2,1-3H3,(H,28,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP4 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Rattus norvegicus) | BDBM50293512
(3-(3-((N-(4-tert-butylbenzyl)-4-chlorophenylsulfon...)Show SMILES CC(C)(C)c1ccc(CN(Cc2cccc(CCC(O)=O)c2)S(=O)(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C27H30ClNO4S/c1-27(2,3)23-10-7-21(8-11-23)18-29(34(32,33)25-14-12-24(28)13-15-25)19-22-6-4-5-20(17-22)9-16-26(30)31/h4-8,10-15,17H,9,16,18-19H2,1-3H3,(H,30,31) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by ChEMBL
| Assay Description Inhibition of rat EP2 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 19: 2075-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.059 BindingDB Entry DOI: 10.7270/Q2PR7W18 |
More data for this Ligand-Target Pair | |