Compile Data Set for Download or QSAR

Found 49 hits Enz. Inhib. hit(s) with all data for entry = 50030557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50298032 ((S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)py...) Show SMILES Clc1ccccc1CN([C@H]1CCN(CC#N)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H18Cl2N4/c21-19-4-2-1-3-16(19)13-26(18-7-9-25(14-18)10-8-23)17-6-5-15(12-24)20(22)11-17/h1-6,11,18H,7,9-10,13-14H2/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298033 ((S)-ethyl 2-(3-((3-chloro-4-cyanophenyl)(2-chlorob...) Show SMILES CCOC(=O)CN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C22H23Cl2N3O2/c1-2-29-22(28)15-26-10-9-19(14-26)27(13-17-5-3-4-6-20(17)23)18-8-7-16(12-25)21(24)11-18/h3-8,11,19H,2,9-10,13-15H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298030 ((S)-2-chloro-4-((2-chlorobenzyl)(1-(3,3,3-trifluor...) Show SMILES FC(F)(F)CCN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C21H20Cl2F3N3/c22-19-4-2-1-3-16(19)13-29(17-6-5-15(12-27)20(23)11-17)18-7-9-28(14-18)10-8-21(24,25)26/h1-6,11,18H,7-10,13-14H2/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298028 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3/c1-26-9-8-17(13-26)27(16-7-6-14(11-25)19(21)10-16)12-15-4-2-3-5-18(15)20(22,23)24/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50298035 ((S)-2-chloro-4-((2-chlorobenzyl)(1-(pyridin-2-ylme...) Show SMILES Clc1ccccc1CN([C@H]1CCN(Cc2ccccn2)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C24H22Cl2N4/c25-23-7-2-1-5-19(23)15-30(21-9-8-18(14-27)24(26)13-21)22-10-12-29(17-22)16-20-6-3-4-11-28-20/h1-9,11,13,22H,10,12,15-17H2/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298043 ((S)-2-chloro-4-((2-chlorobenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H19Cl2N3/c1-23-9-8-17(13-23)24(12-15-4-2-3-5-18(15)20)16-7-6-14(11-22)19(21)10-16/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298029 ((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropylpyrrol...) Show SMILES CC(C)N1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C21H23Cl2N3/c1-15(2)25-10-9-19(14-25)26(13-17-5-3-4-6-20(17)22)18-8-7-16(12-24)21(23)11-18/h3-8,11,15,19H,9-10,13-14H2,1-2H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298031 ((S)-2-chloro-4-((2-chlorobenzyl)(1-(2-methoxyethyl...) Show SMILES COCCN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C21H23Cl2N3O/c1-27-11-10-25-9-8-19(15-25)26(14-17-4-2-3-5-20(17)22)18-7-6-16(13-24)21(23)12-18/h2-7,12,19H,8-11,14-15H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298041 ((S)-4-(benzyl(1-methylpyrrolidin-3-yl)amino)-2-chl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H20ClN3/c1-22-10-9-18(14-22)23(13-15-5-3-2-4-6-15)17-8-7-16(12-21)19(20)11-17/h2-8,11,18H,9-10,13-14H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298046 ((S)-2-chloro-4-((2,6-dichlorobenzyl)(1-methylpyrro...) Show SMILES CN1CC[C@@H](C1)N(Cc1c(Cl)cccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H18Cl3N3/c1-24-8-7-15(11-24)25(12-16-17(20)3-2-4-18(16)21)14-6-5-13(10-23)19(22)9-14/h2-6,9,15H,7-8,11-12H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298047 ((S)-2-chloro-4-((2-methylbenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H22ClN3/c1-15-5-3-4-6-17(15)13-24(19-9-10-23(2)14-19)18-8-7-16(12-22)20(21)11-18/h3-8,11,19H,9-10,13-14H2,1-2H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298034 ((S)-2-(3-((3-chloro-4-cyanophenyl)(2-chlorobenzyl)...) Show SMILES NC(=O)CN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H20Cl2N4O/c21-18-4-2-1-3-15(18)11-26(16-6-5-14(10-23)19(22)9-16)17-7-8-25(12-17)13-20(24)27/h1-6,9,17H,7-8,11-13H2,(H2,24,27)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298040 ((S)-2-chloro-4-((cyclohexylmethyl)(1-methylpyrroli...) Show SMILES CN1CC[C@@H](C1)N(CC1CCCCC1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H26ClN3/c1-22-10-9-18(14-22)23(13-15-5-3-2-4-6-15)17-8-7-16(12-21)19(20)11-17/h7-8,11,15,18H,2-6,9-10,13-14H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298036 (CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...) Show SMILES CC(N(CC(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(=O)N(C)C Show InChI InChI=1S/C15H15F6N3O/c1-9(13(25)23(2)3)24(8-14(16,17)18)11-5-4-10(7-22)12(6-11)15(19,20)21/h4-6,9H,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50298044 ((S)-2-chloro-4-((3-chlorobenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1cccc(Cl)c1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H19Cl2N3/c1-23-8-7-18(13-23)24(12-14-3-2-4-16(20)9-14)17-6-5-15(11-22)19(21)10-17/h2-6,9-10,18H,7-8,12-13H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50298028 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3/c1-26-9-8-17(13-26)27(16-7-6-14(11-25)19(21)10-16)12-15-4-2-3-5-18(15)20(22,23)24/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to AR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298039 ((S)-4-(butyl(1-methylpyrrolidin-3-yl)amino)-2-chlo...) Show SMILES CCCCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C16H22ClN3/c1-3-4-8-20(15-7-9-19(2)12-15)14-6-5-13(11-18)16(17)10-14/h5-6,10,15H,3-4,7-9,12H2,1-2H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298045 ((S)-2-chloro-4-((4-chlorobenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccc(Cl)cc1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H19Cl2N3/c1-23-9-8-18(13-23)24(12-14-2-5-16(20)6-3-14)17-7-4-15(11-22)19(21)10-17/h2-7,10,18H,8-9,12-13H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298038 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(propyl)a...) Show SMILES CCCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C15H20ClN3/c1-3-7-19(14-6-8-18(2)11-14)13-5-4-12(10-17)15(16)9-13/h4-5,9,14H,3,6-8,11H2,1-2H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298037 ((S)-2-chloro-4-(ethyl(1-methylpyrrolidin-3-yl)amin...) Show SMILES CCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C14H18ClN3/c1-3-18(13-6-7-17(2)10-13)12-5-4-11(9-16)14(15)8-12/h4-5,8,13H,3,6-7,10H2,1-2H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50298036 (CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...) Show SMILES CC(N(CC(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(=O)N(C)C Show InChI InChI=1S/C15H15F6N3O/c1-9(13(25)23(2)3)24(8-14(16,17)18)11-5-4-10(7-22)12(6-11)15(19,20)21/h4-6,9H,8H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to AR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298042 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(pyridin-...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccn1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C18H19ClN4/c1-22-9-7-17(13-22)23(12-15-4-2-3-8-21-15)16-6-5-14(11-20)18(19)10-16/h2-6,8,10,17H,7,9,12-13H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to PR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50298028 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3/c1-26-9-8-17(13-26)27(16-7-6-14(11-25)19(21)10-16)12-15-4-2-3-5-18(15)20(22,23)24/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to ERbeta by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50298036 (CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...) Show SMILES CC(N(CC(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(=O)N(C)C Show InChI InChI=1S/C15H15F6N3O/c1-9(13(25)23(2)3)24(8-14(16,17)18)11-5-4-10(7-22)12(6-11)15(19,20)21/h4-6,9H,8H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to ERbeta by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50298036 (CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...) Show SMILES CC(N(CC(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(=O)N(C)C Show InChI InChI=1S/C15H15F6N3O/c1-9(13(25)23(2)3)24(8-14(16,17)18)11-5-4-10(7-22)12(6-11)15(19,20)21/h4-6,9H,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to GR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50298036 (CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...) Show SMILES CC(N(CC(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(=O)N(C)C Show InChI InChI=1S/C15H15F6N3O/c1-9(13(25)23(2)3)24(8-14(16,17)18)11-5-4-10(7-22)12(6-11)15(19,20)21/h4-6,9H,8H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to MR by fluorescence polarization based competition binding assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50298028 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3/c1-26-9-8-17(13-26)27(16-7-6-14(11-25)19(21)10-16)12-15-4-2-3-5-18(15)20(22,23)24/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at GR expressed in human A549 cell line				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50298028 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3/c1-26-9-8-17(13-26)27(16-7-6-14(11-25)19(21)10-16)12-15-4-2-3-5-18(15)20(22,23)24/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at MR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298047 ((S)-2-chloro-4-((2-methylbenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H22ClN3/c1-15-5-3-4-6-17(15)13-24(19-9-10-23(2)14-19)18-8-7-16(12-22)20(21)11-18/h3-8,11,19H,9-10,13-14H2,1-2H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298046 ((S)-2-chloro-4-((2,6-dichlorobenzyl)(1-methylpyrro...) Show SMILES CN1CC[C@@H](C1)N(Cc1c(Cl)cccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H18Cl3N3/c1-24-8-7-15(11-24)25(12-16-17(20)3-2-4-18(16)21)14-6-5-13(10-23)19(22)9-14/h2-6,9,15H,7-8,11-12H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298045 ((S)-2-chloro-4-((4-chlorobenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccc(Cl)cc1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H19Cl2N3/c1-23-9-8-18(13-23)24(12-14-2-5-16(20)6-3-14)17-7-4-15(11-22)19(21)10-17/h2-7,10,18H,8-9,12-13H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298044 ((S)-2-chloro-4-((3-chlorobenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1cccc(Cl)c1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H19Cl2N3/c1-23-8-7-18(13-23)24(12-14-3-2-4-16(20)9-14)17-6-5-15(11-22)19(21)10-17/h2-6,9-10,18H,7-8,12-13H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298043 ((S)-2-chloro-4-((2-chlorobenzyl)(1-methylpyrrolidi...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H19Cl2N3/c1-23-9-8-17(13-23)24(12-15-4-2-3-5-18(15)20)16-7-6-14(11-22)19(21)10-16/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298042 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(pyridin-...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccn1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C18H19ClN4/c1-22-9-7-17(13-22)23(12-15-4-2-3-8-21-15)16-6-5-14(11-20)18(19)10-16/h2-6,8,10,17H,7,9,12-13H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298041 ((S)-4-(benzyl(1-methylpyrrolidin-3-yl)amino)-2-chl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H20ClN3/c1-22-10-9-18(14-22)23(13-15-5-3-2-4-6-15)17-8-7-16(12-21)19(20)11-17/h2-8,11,18H,9-10,13-14H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298040 ((S)-2-chloro-4-((cyclohexylmethyl)(1-methylpyrroli...) Show SMILES CN1CC[C@@H](C1)N(CC1CCCCC1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C19H26ClN3/c1-22-10-9-18(14-22)23(13-15-5-3-2-4-6-15)17-8-7-16(12-21)19(20)11-17/h7-8,11,15,18H,2-6,9-10,13-14H2,1H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298039 ((S)-4-(butyl(1-methylpyrrolidin-3-yl)amino)-2-chlo...) Show SMILES CCCCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C16H22ClN3/c1-3-4-8-20(15-7-9-19(2)12-15)14-6-5-13(11-18)16(17)10-14/h5-6,10,15H,3-4,7-9,12H2,1-2H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298038 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(propyl)a...) Show SMILES CCCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C15H20ClN3/c1-3-7-19(14-6-8-18(2)11-14)13-5-4-12(10-17)15(16)9-13/h4-5,9,14H,3,6-8,11H2,1-2H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298037 ((S)-2-chloro-4-(ethyl(1-methylpyrrolidin-3-yl)amin...) Show SMILES CCN([C@H]1CCN(C)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C14H18ClN3/c1-3-18(13-6-7-17(2)10-13)12-5-4-11(9-16)14(15)8-12/h4-5,8,13H,3,6-7,10H2,1-2H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298036 (CHEMBL549725 | rac 2-((4-cyano-3-(trifluoromethyl)...) Show SMILES CC(N(CC(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C(=O)N(C)C Show InChI InChI=1S/C15H15F6N3O/c1-9(13(25)23(2)3)24(8-14(16,17)18)11-5-4-10(7-22)12(6-11)15(19,20)21/h4-6,9H,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50298028 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3/c1-26-9-8-17(13-26)27(16-7-6-14(11-25)19(21)10-16)12-15-4-2-3-5-18(15)20(22,23)24/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in human T47D cells				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50298035 ((S)-2-chloro-4-((2-chlorobenzyl)(1-(pyridin-2-ylme...) Show SMILES Clc1ccccc1CN([C@H]1CCN(Cc2ccccn2)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C24H22Cl2N4/c25-23-7-2-1-5-19(23)15-30(21-9-8-18(14-27)24(26)13-21)22-10-12-29(17-22)16-20-6-3-4-11-28-20/h1-9,11,13,22H,10,12,15-17H2/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298034 ((S)-2-(3-((3-chloro-4-cyanophenyl)(2-chlorobenzyl)...) Show SMILES NC(=O)CN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H20Cl2N4O/c21-18-4-2-1-3-15(18)11-26(16-6-5-14(10-23)19(22)9-16)17-7-8-25(12-17)13-20(24)27/h1-6,9,17H,7-8,11-13H2,(H2,24,27)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298033 ((S)-ethyl 2-(3-((3-chloro-4-cyanophenyl)(2-chlorob...) Show SMILES CCOC(=O)CN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C22H23Cl2N3O2/c1-2-29-22(28)15-26-10-9-19(14-26)27(13-17-5-3-4-6-20(17)23)18-8-7-16(12-25)21(24)11-18/h3-8,11,19H,2,9-10,13-15H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298032 ((S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)py...) Show SMILES Clc1ccccc1CN([C@H]1CCN(CC#N)C1)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H18Cl2N4/c21-19-4-2-1-3-16(19)13-26(18-7-9-25(14-18)10-8-23)17-6-5-15(12-24)20(22)11-17/h1-6,11,18H,7,9-10,13-14H2/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298031 ((S)-2-chloro-4-((2-chlorobenzyl)(1-(2-methoxyethyl...) Show SMILES COCCN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C21H23Cl2N3O/c1-27-11-10-25-9-8-19(15-25)26(14-17-4-2-3-5-20(17)22)18-7-6-16(13-24)21(23)12-18/h2-7,12,19H,8-11,14-15H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298030 ((S)-2-chloro-4-((2-chlorobenzyl)(1-(3,3,3-trifluor...) Show SMILES FC(F)(F)CCN1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C21H20Cl2F3N3/c22-19-4-2-1-3-16(19)13-29(17-6-5-15(12-27)20(23)11-17)18-7-9-28(14-18)10-8-21(24,25)26/h1-6,11,18H,7-10,13-14H2/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298029 ((S)-2-chloro-4-((2-chlorobenzyl)(1-isopropylpyrrol...) Show SMILES CC(C)N1CC[C@@H](C1)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C21H23Cl2N3/c1-15(2)25-10-9-19(14-25)26(13-17-5-3-4-6-20(17)22)18-8-7-16(12-24)21(23)11-18/h3-8,11,15,19H,9-10,13-14H2,1-2H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50298028 ((S)-2-chloro-4-((1-methylpyrrolidin-3-yl)(2-(trifl...) Show SMILES CN1CC[C@@H](C1)N(Cc1ccccc1C(F)(F)F)c1ccc(C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClF3N3/c1-26-9-8-17(13-26)27(16-7-6-14(11-25)19(21)10-16)12-15-4-2-3-5-18(15)20(22,23)24/h2-7,10,17H,8-9,12-13H2,1H3/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assay				Bioorg Med Chem Lett 19: 4777-80 (2009) Article DOI: 10.1016/j.bmcl.2009.06.055 BindingDB Entry DOI: 10.7270/Q2TB16XG
					More data for this Ligand-Target Pair				3D Structure (crystal)