Compile Data Set for Download or QSAR

Found 38 hits Enz. Inhib. hit(s) with all data for entry = 50048111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204672 (CHEMBL3961059) Show SMILES CNCc1ccc(Cl)c(c1)-c1ccccc1OC Show InChI InChI=1S/C15H16ClNO/c1-17-10-11-7-8-14(16)13(9-11)12-5-3-4-6-15(12)18-2/h3-9,17H,10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204667 (CHEMBL3943658) Show SMILES CNCc1ccc(C)c(c1)-c1ccccc1OC Show InChI InChI=1S/C16H19NO/c1-12-8-9-13(11-17-2)10-15(12)14-6-4-5-7-16(14)18-3/h4-10,17H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204668 (CHEMBL3928716) Show SMILES COc1ccccc1N1CCN(Cc2cccc(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C25H28N2O2/c1-28-24-12-5-3-10-22(24)21-9-7-8-20(18-21)19-26-14-16-27(17-15-26)23-11-4-6-13-25(23)29-2/h3-13,18H,14-17,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in CHO-K1 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204678 (CHEMBL3931889) Show SMILES COc1ccccc1-c1cc(CN(C)C)ccc1Cl Show InChI InChI=1S/C16H18ClNO/c1-18(2)11-12-8-9-15(17)14(10-12)13-6-4-5-7-16(13)19-3/h4-10H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204674 (CHEMBL3892079) Show SMILES COc1ccccc1N1CCN(Cc2ccc(C)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H30N2O2/c1-20-12-13-21(18-23(20)22-8-4-6-10-25(22)29-2)19-27-14-16-28(17-15-27)24-9-5-7-11-26(24)30-3/h4-13,18H,14-17,19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204677 (CHEMBL3901042) Show SMILES COc1ccccc1-c1cc(CN(C)C)ccc1C Show InChI InChI=1S/C17H21NO/c1-13-9-10-14(12-18(2)3)11-16(13)15-7-5-6-8-17(15)19-4/h5-11H,12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204673 (CHEMBL3927929) Show SMILES COc1ccccc1N1CCN(Cc2cc3OCOc3c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H28N2O4/c1-29-23-9-5-3-7-20(23)21-15-19(16-25-26(21)32-18-31-25)17-27-11-13-28(14-12-27)22-8-4-6-10-24(22)30-2/h3-10,15-16H,11-14,17-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204666 (CHEMBL3984812) Show SMILES COc1ccccc1N1CCN(Cc2ccc(Cl)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C25H27ClN2O2/c1-29-24-9-5-3-7-20(24)21-17-19(11-12-22(21)26)18-27-13-15-28(16-14-27)23-8-4-6-10-25(23)30-2/h3-12,17H,13-16,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204671 (CHEMBL3973160) Show SMILES COc1ccccc1N1CCN(Cc2ccc(OC)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H30N2O3/c1-29-24-10-6-4-8-21(24)22-18-20(12-13-25(22)30-2)19-27-14-16-28(17-15-27)23-9-5-7-11-26(23)31-3/h4-13,18H,14-17,19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204670 (CHEMBL3918663) Show SMILES COc1ccccc1-c1cccc(CN(C)C)c1 Show InChI InChI=1S/C16H19NO/c1-17(2)12-13-7-6-8-14(11-13)15-9-4-5-10-16(15)18-3/h4-11H,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204679 (CHEMBL3952849) Show SMILES CNCc1cccc(c1)-c1ccccc1OC Show InChI InChI=1S/C15H17NO/c1-16-11-12-6-5-7-13(10-12)14-8-3-4-9-15(14)17-2/h3-10,16H,11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	226	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204682 (CHEMBL3959382) Show SMILES COc1ccccc1-c1cc(CN2CCC(C)CC2)ccc1Cl Show InChI InChI=1S/C20H24ClNO/c1-15-9-11-22(12-10-15)14-16-7-8-19(21)18(13-16)17-5-3-4-6-20(17)23-2/h3-8,13,15H,9-12,14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	389	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204664 (CHEMBL3899934) Show SMILES CNCc1ccc(OC)c(c1)-c1ccccc1OC Show InChI InChI=1S/C16H19NO2/c1-17-11-12-8-9-16(19-3)14(10-12)13-6-4-5-7-15(13)18-2/h4-10,17H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	648	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204681 (CHEMBL3967387) Show SMILES COc1ccccc1-c1cc(CN2CCC(C)CC2)cc2OCOc12 Show InChI InChI=1S/C21H25NO3/c1-15-7-9-22(10-8-15)13-16-11-18(21-20(12-16)24-14-25-21)17-5-3-4-6-19(17)23-2/h3-6,11-12,15H,7-10,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	691	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204683 (CHEMBL3937741) Show SMILES COc1ccccc1-c1cc(CN(C)C)cc2OCOc12 Show InChI InChI=1S/C17H19NO3/c1-18(2)10-12-8-14(17-16(9-12)20-11-21-17)13-6-4-5-7-15(13)19-3/h4-9H,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	772	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204676 (CHEMBL3948597) Show SMILES COc1ccccc1-c1cc(CN(C)C)ccc1OC Show InChI InChI=1S/C17H21NO2/c1-18(2)12-13-9-10-17(20-4)15(11-13)14-7-5-6-8-16(14)19-3/h5-11H,12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204680 (CHEMBL3906019) Show SMILES COc1ccccc1-c1cccc(CN2CCC(C)CC2)c1 Show InChI InChI=1S/C20H25NO/c1-16-10-12-21(13-11-16)15-17-6-5-7-18(14-17)19-8-3-4-9-20(19)22-2/h3-9,14,16H,10-13,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204665 (CHEMBL3972166) Show SMILES COc1ccccc1-c1cc(CN2CCC(C)CC2)ccc1C Show InChI InChI=1S/C21H27NO/c1-16-10-12-22(13-11-16)15-18-9-8-17(2)20(14-18)19-6-4-5-7-21(19)23-3/h4-9,14,16H,10-13,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204675 (CHEMBL3956286) Show SMILES CNCc1cc2OCOc2c(c1)-c1ccccc1OC Show InChI InChI=1S/C16H17NO3/c1-17-9-11-7-13(16-15(8-11)19-10-20-16)12-5-3-4-6-14(12)18-2/h3-8,17H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204669 (CHEMBL3952371) Show SMILES COc1ccccc1-c1cc(CN2CCC(C)CC2)ccc1OC Show InChI InChI=1S/C21H27NO2/c1-16-10-12-22(13-11-16)15-17-8-9-21(24-3)19(14-17)18-6-4-5-7-20(18)23-2/h4-9,14,16H,10-13,15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50098551 ((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...) Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204671 (CHEMBL3973160) Show SMILES COc1ccccc1N1CCN(Cc2ccc(OC)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H30N2O3/c1-29-24-10-6-4-8-21(24)22-18-20(12-13-25(22)30-2)19-27-14-16-28(17-15-27)23-9-5-7-11-26(23)31-3/h4-13,18H,14-17,19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204671 (CHEMBL3973160) Show SMILES COc1ccccc1N1CCN(Cc2ccc(OC)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H30N2O3/c1-29-24-10-6-4-8-21(24)22-18-20(12-13-25(22)30-2)19-27-14-16-28(17-15-27)23-9-5-7-11-26(23)31-3/h4-13,18H,14-17,19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204674 (CHEMBL3892079) Show SMILES COc1ccccc1N1CCN(Cc2ccc(C)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H30N2O2/c1-20-12-13-21(18-23(20)22-8-4-6-10-25(22)29-2)19-27-14-16-28(17-15-27)24-9-5-7-11-26(24)30-3/h4-13,18H,14-17,19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204674 (CHEMBL3892079) Show SMILES COc1ccccc1N1CCN(Cc2ccc(C)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H30N2O2/c1-20-12-13-21(18-23(20)22-8-4-6-10-25(22)29-2)19-27-14-16-28(17-15-27)24-9-5-7-11-26(24)30-3/h4-13,18H,14-17,19H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204673 (CHEMBL3927929) Show SMILES COc1ccccc1N1CCN(Cc2cc3OCOc3c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H28N2O4/c1-29-23-9-5-3-7-20(23)21-15-19(16-25-26(21)32-18-31-25)17-27-11-13-28(14-12-27)22-8-4-6-10-24(22)30-2/h3-10,15-16H,11-14,17-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204673 (CHEMBL3927929) Show SMILES COc1ccccc1N1CCN(Cc2cc3OCOc3c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C26H28N2O4/c1-29-23-9-5-3-7-20(23)21-15-19(16-25-26(21)32-18-31-25)17-27-11-13-28(14-12-27)22-8-4-6-10-24(22)30-2/h3-10,15-16H,11-14,17-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204666 (CHEMBL3984812) Show SMILES COc1ccccc1N1CCN(Cc2ccc(Cl)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C25H27ClN2O2/c1-29-24-9-5-3-7-20(24)21-17-19(11-12-22(21)26)18-27-13-15-28(16-14-27)23-8-4-6-10-25(23)30-2/h3-12,17H,13-16,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204666 (CHEMBL3984812) Show SMILES COc1ccccc1N1CCN(Cc2ccc(Cl)c(c2)-c2ccccc2OC)CC1 Show InChI InChI=1S/C25H27ClN2O2/c1-29-24-9-5-3-7-20(24)21-17-19(11-12-22(21)26)18-27-13-15-28(16-14-27)23-8-4-6-10-25(23)30-2/h3-12,17H,13-16,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT7R expressed in HEK293 cells assessed as inhibition of serotonin stimulated-cAMP levels preincubated for 10 mins fol...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204672 (CHEMBL3961059) Show SMILES CNCc1ccc(Cl)c(c1)-c1ccccc1OC Show InChI InChI=1S/C15H16ClNO/c1-17-10-11-7-8-14(16)13(9-11)12-5-3-4-6-15(12)18-2/h3-9,17H,10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204667 (CHEMBL3943658) Show SMILES CNCc1ccc(C)c(c1)-c1ccccc1OC Show InChI InChI=1S/C16H19NO/c1-12-8-9-13(11-17-2)10-15(12)14-6-4-5-7-16(14)18-3/h4-10,17H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204667 (CHEMBL3943658) Show SMILES CNCc1ccc(C)c(c1)-c1ccccc1OC Show InChI InChI=1S/C16H19NO/c1-12-8-9-13(11-17-2)10-15(12)14-6-4-5-7-16(14)18-3/h4-10,17H,11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204672 (CHEMBL3961059) Show SMILES CNCc1ccc(Cl)c(c1)-c1ccccc1OC Show InChI InChI=1S/C15H16ClNO/c1-17-10-11-7-8-14(16)13(9-11)12-5-3-4-6-15(12)18-2/h3-9,17H,10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair