Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase (Pseudomonas aeruginosa) | BDBM50336510 (7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-1,10-dihyd...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toho University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis | Antimicrob Agents Chemother 54: 3625-9 (2010) Article DOI: 10.1128/AAC.01397-09 BindingDB Entry DOI: 10.7270/Q29C6XQ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Pseudomonas aeruginosa) | BDBM50336511 ((4R,5S,6S)-3-(benzo[b]thiophen-2-ylthio)-6-((R)-1-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toho University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis | Antimicrob Agents Chemother 54: 3625-9 (2010) Article DOI: 10.1128/AAC.01397-09 BindingDB Entry DOI: 10.7270/Q29C6XQ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Pseudomonas aeruginosa) | BDBM50336509 (CHEMBL116455 | Mercapto-acetic acid | Mercaptoacet...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toho University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis | Antimicrob Agents Chemother 54: 3625-9 (2010) Article DOI: 10.1128/AAC.01397-09 BindingDB Entry DOI: 10.7270/Q29C6XQ2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-lactamase (Pseudomonas aeruginosa) | BDBM50121953 (2-mercaptoethanecarboxylic acid | 3-mercaptopropan...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toho University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis | Antimicrob Agents Chemother 54: 3625-9 (2010) Article DOI: 10.1128/AAC.01397-09 BindingDB Entry DOI: 10.7270/Q29C6XQ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (Pseudomonas aeruginosa) | BDBM50336508 (CHEMBL1673299 | sodium 2,3-diethylmaleate) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toho University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa beta-lactamase IMP-1 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis | Antimicrob Agents Chemother 54: 3625-9 (2010) Article DOI: 10.1128/AAC.01397-09 BindingDB Entry DOI: 10.7270/Q29C6XQ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metallo-beta-lactamase VIM-2 (Pseudomonas aeruginosa (g-Proteobacteria)) | BDBM50336508 (CHEMBL1673299 | sodium 2,3-diethylmaleate) | PDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Toho University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa beta-lactamase VIM-2 assessed as hydrolysis of nitrocefin by UV spectrophotometric analysis | Antimicrob Agents Chemother 54: 3625-9 (2010) Article DOI: 10.1128/AAC.01397-09 BindingDB Entry DOI: 10.7270/Q29C6XQ2 | |||||||||||
More data for this Ligand-Target Pair |