Found 37 hits Enz. Inhib. hit(s) with all data for entry = 50041164 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405789
(CHEMBL412984)Show SMILES CC(C)C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(C)=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](C)C(N)=O Show InChI InChI=1S/C69H92Cl2N18O13/c1-37(2)30-51(60(95)83-50(13-8-28-78-69(75)76)67(102)89-29-9-14-57(89)66(101)80-38(3)58(72)93)84-59(94)49(12-7-27-77-68(73)74)82-62(97)53(33-42-19-25-46(92)26-20-42)86-65(100)56(36-90)88-64(99)55(34-43-35-79-48-11-6-5-10-47(43)48)87-63(98)54(32-41-17-23-45(71)24-18-41)85-61(96)52(81-39(4)91)31-40-15-21-44(70)22-16-40/h5-6,10-11,15-26,35,37-38,49-57,79,90,92H,7-9,12-14,27-34,36H2,1-4H3,(H2,72,93)(H,80,101)(H,81,91)(H,82,97)(H,83,95)(H,84,94)(H,85,96)(H,86,100)(H,87,98)(H,88,99)(H4,73,74,77)(H4,75,76,78)/t38-,49-,50-,51+,52-,53+,54-,55-,56+,57-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0182 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405770
(CHEMBL216617)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1cccc2ccccc12 Show InChI InChI=1S/C57H72N10O9/c1-4-60-55(75)49-19-11-29-67(49)56(76)44(18-10-28-61-57(58)59)63-51(71)45(30-35(2)3)64-53(73)47(33-37-20-23-38-12-5-6-14-41(38)31-37)65-52(72)46(32-36-21-25-42(69)26-22-36)66-54(74)48(34-68)62-50(70)27-24-40-16-9-15-39-13-7-8-17-43(39)40/h5-9,12-17,20-23,25-26,31,35,44-49,68-69H,4,10-11,18-19,24,27-30,32-34H2,1-3H3,(H,60,75)(H,62,70)(H,63,71)(H,64,73)(H,65,72)(H,66,74)(H4,58,59,61)/t44-,45-,46-,47+,48-,49?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.282 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405767
(CHEMBL265413)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CC12CC3CC(CC(C3)C1)C2 |TLB:71:70:73:66.65.67,71:66:73:70.72.69,THB:69:68:65:70.72.71,69:70:65:68.73.67| Show InChI InChI=1S/C54H77N11O9/c1-4-57-51(73)45-12-8-18-65(45)52(74)40(11-7-17-58-53(55)56)61-47(69)41(19-31(2)3)62-49(71)43(24-36-29-59-39-10-6-5-9-38(36)39)64-48(70)42(23-32-13-15-37(67)16-14-32)63-50(72)44(30-66)60-46(68)28-54-25-33-20-34(26-54)22-35(21-33)27-54/h5-6,9-10,13-16,29,31,33-35,40-45,59,66-67H,4,7-8,11-12,17-28,30H2,1-3H3,(H,57,73)(H,60,68)(H,61,69)(H,62,71)(H,63,72)(H,64,70)(H4,55,56,58)/t33?,34?,35?,40-,41-,42-,43+,44-,45?,54?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.457 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405769
(CHEMBL275694)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1cccc2ccccc12 Show InChI InChI=1S/C55H71N11O9/c1-4-58-53(74)47-19-11-27-66(47)54(75)42(18-10-26-59-55(56)57)62-49(70)43(28-33(2)3)63-51(72)45(30-37-31-60-41-17-8-7-16-40(37)41)65-50(71)44(29-34-20-23-38(68)24-21-34)64-52(73)46(32-67)61-48(69)25-22-36-14-9-13-35-12-5-6-15-39(35)36/h5-9,12-17,20-21,23-24,31,33,42-47,60,67-68H,4,10-11,18-19,22,25-30,32H2,1-3H3,(H,58,74)(H,61,69)(H,62,70)(H,63,72)(H,64,73)(H,65,71)(H4,56,57,59)/t42-,43-,44-,45+,46-,47?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.525 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405764
(CHEMBL264298)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C61H75N11O9/c1-4-64-59(79)53-24-14-30-72(53)60(80)48(23-13-29-65-61(62)63)68-55(75)49(31-38(2)3)69-57(77)51(33-43-35-66-47-22-11-10-21-46(43)47)71-56(76)50(32-39-25-27-44(73)28-26-39)70-58(78)52(37-81-36-40-15-6-5-7-16-40)67-54(74)34-42-19-12-18-41-17-8-9-20-45(41)42/h5-12,15-22,25-28,35,38,48-53,66,73H,4,13-14,23-24,29-34,36-37H2,1-3H3,(H,64,79)(H,67,74)(H,68,75)(H,69,77)(H,70,78)(H,71,76)(H4,62,63,65)/t48-,49-,50-,51+,52-,53?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50422274
(GONADORELIN | Human gonadoliberin-i)Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O Show InChI InChI=1S/C55H75N17O13/c1-29(2)19-38(49(80)67-37(9-5-17-60-55(57)58)54(85)72-18-6-10-43(72)53(84)62-25-44(56)75)66-46(77)26-63-47(78)39(20-30-11-13-33(74)14-12-30)68-52(83)42(27-73)71-50(81)40(21-31-23-61-35-8-4-3-7-34(31)35)69-51(82)41(22-32-24-59-28-64-32)70-48(79)36-15-16-45(76)65-36/h3-4,7-8,11-14,23-24,28-29,36-43,61,73-74H,5-6,9-10,15-22,25-27H2,1-2H3,(H2,56,75)(H,59,64)(H,62,84)(H,63,78)(H,65,76)(H,66,77)(H,67,80)(H,68,83)(H,69,82)(H,70,79)(H,71,81)(H4,57,58,60)/t36-,37-,38-,39-,40-,41-,42-,43-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405772
(CHEMBL2369787)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)\C=C/c1ccc(OC)cc1 |wU:5.4,31.32,45.48,23.24,wD:57.61,12.13,(32.43,-18.06,;30.96,-17.65,;30.57,-16.16,;29.09,-15.76,;27.98,-16.85,;28.68,-14.27,;29.66,-13.08,;28.83,-11.78,;27.33,-12.17,;27.24,-13.7,;25.92,-12.93,;25.94,-11.4,;24.6,-13.7,;24.58,-15.24,;25.89,-16.05,;25.86,-17.57,;27.21,-18.35,;27.17,-19.89,;25.85,-20.65,;28.51,-20.68,;23.25,-12.92,;21.91,-13.7,;21.95,-15.24,;20.59,-12.96,;20.57,-11.4,;21.88,-10.63,;23.23,-11.38,;21.88,-9.09,;19.25,-13.74,;17.91,-12.97,;17.91,-11.43,;16.59,-13.76,;16.59,-15.3,;17.94,-16.05,;19.35,-15.43,;20.37,-16.56,;19.63,-17.89,;20.12,-19.37,;19.09,-20.5,;17.57,-20.21,;17.09,-18.74,;18.1,-17.58,;15.24,-13,;13.92,-13.77,;13.93,-15.31,;12.55,-13.02,;12.55,-11.46,;13.89,-10.69,;15.23,-11.45,;16.56,-10.66,;16.55,-9.12,;17.87,-8.35,;15.21,-8.37,;13.86,-9.15,;11.24,-13.8,;9.89,-13.03,;9.89,-11.49,;8.57,-13.83,;8.57,-15.36,;9.92,-16.11,;7.23,-13.06,;5.88,-13.83,;5.91,-15.39,;4.55,-13.08,;3.22,-13.86,;3.22,-15.4,;4.56,-16.14,;4.56,-17.68,;3.24,-18.47,;3.25,-19.99,;4.59,-20.76,;1.9,-17.71,;1.9,-16.17,)| Show InChI InChI=1S/C52H69N11O10/c1-5-55-50(71)44-13-9-25-63(44)51(72)39(12-8-24-56-52(53)54)59-46(67)40(26-31(2)3)60-48(69)42(28-34-29-57-38-11-7-6-10-37(34)38)62-47(68)41(27-33-14-19-35(65)20-15-33)61-49(70)43(30-64)58-45(66)23-18-32-16-21-36(73-4)22-17-32/h6-7,10-11,14-23,29,31,39-44,57,64-65H,5,8-9,12-13,24-28,30H2,1-4H3,(H,55,71)(H,58,66)(H,59,67)(H,60,69)(H,61,70)(H,62,68)(H4,53,54,56)/b23-18-/t39-,40-,41-,42+,43-,44-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405782
(CHEMBL413887)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C56H73N11O9/c1-4-59-54(75)48-18-11-27-67(48)55(76)43(17-10-26-60-56(57)58)63-50(71)44(28-34(2)3)64-52(73)46(31-36-20-23-37-12-5-6-13-38(37)29-36)65-51(72)45(30-35-21-24-40(69)25-22-35)66-53(74)47(33-68)62-49(70)19-9-14-39-32-61-42-16-8-7-15-41(39)42/h5-8,12-13,15-16,20-25,29,32,34,43-48,61,68-69H,4,9-11,14,17-19,26-28,30-31,33H2,1-3H3,(H,59,75)(H,62,70)(H,63,71)(H,64,73)(H,65,72)(H,66,74)(H4,57,58,60)/t43-,44-,45-,46+,47-,48?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405786
(CHEMBL429543)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1c[nH]c2ccccc12 Show InChI InChI=1S/C55H71N11O9/c1-4-58-53(74)47-16-10-26-66(47)54(75)42(15-9-25-59-55(56)57)62-49(70)43(27-33(2)3)63-51(72)45(30-35-17-20-36-11-5-6-12-37(36)28-35)64-50(71)44(29-34-18-22-39(68)23-19-34)65-52(73)46(32-67)61-48(69)24-21-38-31-60-41-14-8-7-13-40(38)41/h5-8,11-14,17-20,22-23,28,31,33,42-47,60,67-68H,4,9-10,15-16,21,24-27,29-30,32H2,1-3H3,(H,58,74)(H,61,69)(H,62,70)(H,63,72)(H,64,71)(H,65,73)(H4,56,57,59)/t42-,43-,44-,45+,46-,47?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405763
(CHEMBL412573)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)COc1cccc2ccccc12 Show InChI InChI=1S/C54H69N11O10/c1-4-57-52(73)45-18-11-25-65(45)53(74)40(17-10-24-58-54(55)56)61-48(69)41(26-32(2)3)62-50(71)43(28-35-29-59-39-16-8-7-14-37(35)39)64-49(70)42(27-33-20-22-36(67)23-21-33)63-51(72)44(30-66)60-47(68)31-75-46-19-9-13-34-12-5-6-15-38(34)46/h5-9,12-16,19-23,29,32,40-45,59,66-67H,4,10-11,17-18,24-28,30-31H2,1-3H3,(H,57,73)(H,60,68)(H,61,69)(H,62,71)(H,63,72)(H,64,70)(H4,55,56,58)/t40-,41-,42-,43+,44-,45?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405783
(CHEMBL2369807)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)Cc1cccc2ccccc12 |wU:5.4,31.32,45.48,23.24,wD:57.61,12.13,(27.95,-13.77,;26.48,-13.39,;26.09,-11.88,;24.61,-11.5,;23.49,-12.58,;24.2,-9.99,;25.18,-8.8,;24.35,-7.52,;22.85,-7.9,;22.76,-9.44,;21.44,-8.67,;21.46,-7.13,;20.11,-9.44,;20.09,-10.98,;21.41,-11.77,;21.4,-13.31,;22.72,-14.09,;22.69,-15.63,;21.37,-16.37,;24.03,-16.4,;18.77,-8.64,;17.43,-9.44,;17.46,-10.98,;16.1,-8.67,;16.08,-7.13,;17.4,-6.36,;18.75,-7.1,;17.4,-4.82,;14.77,-9.46,;13.42,-8.7,;13.42,-7.16,;12.1,-9.47,;12.1,-11.01,;13.45,-11.78,;14.86,-11.14,;15.89,-12.29,;15.14,-13.61,;15.63,-15.09,;14.61,-16.24,;13.09,-15.94,;12.61,-14.48,;13.61,-13.31,;10.76,-8.73,;9.43,-9.51,;9.44,-11.05,;8.06,-8.74,;8.06,-7.2,;9.4,-6.42,;9.38,-4.88,;10.73,-4.09,;12.06,-4.85,;13.39,-4.07,;12.07,-6.39,;10.75,-7.16,;6.75,-9.53,;5.4,-8.77,;5.4,-7.23,;4.09,-9.56,;4.09,-11.08,;5.43,-11.85,;2.74,-8.79,;1.39,-9.57,;1.42,-11.11,;.06,-8.8,;-1.27,-9.59,;-1.25,-11.11,;-2.59,-11.88,;-3.94,-11.13,;-3.94,-9.59,;-5.25,-8.83,;-5.28,-7.29,;-3.94,-6.52,;-2.62,-7.28,;-2.6,-8.82,)| Show InChI InChI=1S/C54H69N11O9/c1-4-57-52(73)46-19-11-25-65(46)53(74)41(18-10-24-58-54(55)56)61-48(69)42(26-32(2)3)62-50(71)44(28-36-30-59-40-17-8-7-16-39(36)40)64-49(70)43(27-33-20-22-37(67)23-21-33)63-51(72)45(31-66)60-47(68)29-35-14-9-13-34-12-5-6-15-38(34)35/h5-9,12-17,20-23,30,32,41-46,59,66-67H,4,10-11,18-19,24-29,31H2,1-3H3,(H,57,73)(H,60,68)(H,61,69)(H,62,71)(H,63,72)(H,64,70)(H4,55,56,58)/t41-,42-,43-,44+,45-,46-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405785
(CHEMBL275709)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C56H70N10O9/c1-4-59-54(74)48-19-11-27-66(48)55(75)43(18-10-26-60-56(57)58)62-50(70)44(28-34(2)3)63-52(72)46(31-36-20-23-37-12-5-6-14-39(37)29-36)64-51(71)45(30-35-21-24-41(68)25-22-35)65-53(73)47(33-67)61-49(69)32-40-16-9-15-38-13-7-8-17-42(38)40/h5-9,12-17,20-25,29,34,43-48,67-68H,4,10-11,18-19,26-28,30-33H2,1-3H3,(H,59,74)(H,61,69)(H,62,70)(H,63,72)(H,64,71)(H,65,73)(H4,57,58,60)/t43-,44-,45-,46+,47-,48?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405784
(CHEMBL415109)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C59H74N10O9/c1-4-62-57(76)51-25-15-31-69(51)58(77)46(24-14-30-63-59(60)61)65-53(72)47(32-38(2)3)66-54(73)48(33-39-16-7-5-8-17-39)67-55(74)49(34-40-26-28-44(70)29-27-40)68-56(75)50(37-78-36-41-18-9-6-10-19-41)64-52(71)35-43-22-13-21-42-20-11-12-23-45(42)43/h5-13,16-23,26-29,38,46-51,70H,4,14-15,24-25,30-37H2,1-3H3,(H,62,76)(H,64,71)(H,65,72)(H,66,73)(H,67,74)(H,68,75)(H4,60,61,63)/t46-,47-,48+,49-,50-,51?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405762
(CHEMBL2369798)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)Cc1ccc2ccccc2c1 |wU:5.4,31.32,45.48,23.24,wD:57.61,12.13,(28.66,-14.42,;27.18,-14.02,;26.8,-12.52,;25.31,-12.13,;24.2,-13.2,;24.91,-10.63,;25.87,-9.44,;25.06,-8.15,;23.56,-8.53,;23.46,-10.07,;22.15,-9.3,;22.17,-7.76,;20.82,-10.07,;20.8,-11.61,;22.12,-12.39,;22.1,-13.93,;23.43,-14.73,;23.4,-16.27,;22.07,-17.01,;24.74,-17.05,;19.47,-9.28,;18.14,-10.07,;18.17,-11.61,;16.81,-9.31,;16.79,-7.77,;18.11,-6.99,;19.45,-7.74,;18.11,-5.45,;15.47,-10.08,;14.13,-9.34,;14.13,-7.8,;12.81,-10.12,;12.81,-11.66,;14.16,-12.42,;15.57,-11.79,;16.6,-12.91,;15.85,-14.26,;16.34,-15.73,;15.31,-16.88,;13.8,-16.57,;13.31,-15.11,;14.32,-13.93,;11.46,-9.35,;10.14,-10.14,;10.15,-11.68,;8.77,-9.38,;8.77,-7.83,;10.11,-7.04,;11.45,-7.81,;12.78,-7.03,;12.77,-5.49,;14.1,-4.69,;11.43,-4.73,;10.08,-5.5,;7.45,-10.15,;6.11,-9.4,;6.11,-7.86,;4.79,-10.18,;4.79,-11.72,;6.14,-12.48,;3.44,-9.41,;2.1,-10.2,;2.13,-11.75,;.77,-9.44,;-.57,-10.21,;-.55,-11.75,;-1.88,-12.52,;-3.23,-11.75,;-4.54,-12.52,;-5.86,-11.77,;-5.87,-10.23,;-4.54,-9.46,;-3.23,-10.21,;-1.89,-9.44,)| Show InChI InChI=1S/C54H69N11O9/c1-4-57-52(73)46-16-10-24-65(46)53(74)41(15-9-23-58-54(55)56)61-48(69)42(25-32(2)3)62-50(71)44(29-37-30-59-40-14-8-7-13-39(37)40)64-49(70)43(27-33-18-21-38(67)22-19-33)63-51(72)45(31-66)60-47(68)28-34-17-20-35-11-5-6-12-36(35)26-34/h5-8,11-14,17-22,26,30,32,41-46,59,66-67H,4,9-10,15-16,23-25,27-29,31H2,1-3H3,(H,57,73)(H,60,68)(H,61,69)(H,62,71)(H,63,72)(H,64,70)(H4,55,56,58)/t41-,42-,43-,44+,45-,46-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50227959
(CHEMBL2369788)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1c[nH]c2ccccc12 |wU:5.4,31.32,45.48,23.24,wD:57.61,12.13,(27.82,-9.83,;26.35,-9.43,;25.96,-7.93,;24.48,-7.54,;23.37,-8.61,;24.07,-6.04,;25.05,-4.85,;24.22,-3.56,;22.72,-3.95,;22.63,-5.49,;21.31,-4.72,;21.33,-3.18,;19.99,-5.49,;19.96,-7.03,;21.28,-7.81,;21.27,-9.35,;22.6,-10.14,;22.56,-11.68,;21.24,-12.43,;23.9,-12.46,;18.64,-4.69,;17.3,-5.49,;17.33,-7.03,;15.98,-4.73,;15.95,-3.19,;17.27,-2.41,;17.27,-.87,;18.62,-3.15,;14.64,-5.5,;13.29,-4.75,;13.29,-3.21,;11.98,-5.53,;11.98,-7.07,;13.32,-7.83,;14.74,-7.2,;15.76,-8.32,;15.01,-9.67,;15.51,-11.14,;14.48,-12.29,;12.96,-11.98,;12.48,-10.52,;13.48,-9.35,;10.63,-4.76,;9.3,-5.55,;9.31,-7.09,;7.93,-4.79,;7.93,-3.24,;9.27,-2.45,;9.25,-.91,;10.6,-.14,;11.93,-.9,;13.26,-.11,;11.94,-2.44,;10.62,-3.22,;6.62,-5.56,;5.27,-4.81,;5.27,-3.27,;3.96,-5.59,;3.96,-7.13,;5.3,-7.89,;2.61,-4.82,;1.26,-5.61,;1.29,-7.16,;-.06,-4.85,;-.09,-3.32,;-1.41,-2.55,;-2.84,-3.19,;-3.87,-2.05,;-3.1,-.71,;-3.59,.76,;-2.57,1.91,;-1.06,1.6,;-.57,.15,;-1.59,-1.03,)| Show InChI InChI=1S/C53H70N12O9/c1-4-56-51(73)45-16-10-24-65(45)52(74)40(15-9-23-57-53(54)55)61-47(69)41(25-31(2)3)62-49(71)43(27-34-29-59-39-14-8-6-12-37(34)39)64-48(70)42(26-32-17-20-35(67)21-18-32)63-50(72)44(30-66)60-46(68)22-19-33-28-58-38-13-7-5-11-36(33)38/h5-8,11-14,17-18,20-21,28-29,31,40-45,58-59,66-67H,4,9-10,15-16,19,22-27,30H2,1-3H3,(H,56,73)(H,60,68)(H,61,69)(H,62,71)(H,63,72)(H,64,70)(H4,54,55,57)/t40-,41-,42-,43+,44-,45-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405781
(CHEMBL2369814)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12 |wU:5.4,31.32,63.68,45.48,23.24,wD:57.61,12.13,(30.12,-15.49,;28.62,-15.1,;28.24,-13.6,;26.76,-13.21,;25.66,-14.29,;26.37,-11.71,;27.34,-10.52,;26.51,-9.24,;25,-9.62,;24.93,-11.16,;23.61,-10.39,;23.62,-8.85,;22.28,-11.16,;22.25,-12.7,;23.58,-13.49,;23.56,-15.03,;24.87,-15.81,;24.86,-17.34,;23.53,-18.08,;26.19,-18.11,;20.93,-10.36,;19.61,-11.16,;19.62,-12.7,;18.27,-10.39,;18.24,-8.85,;19.58,-8.08,;19.56,-6.55,;20.92,-8.82,;16.95,-11.18,;15.6,-10.42,;15.58,-8.89,;14.27,-11.19,;14.29,-12.73,;15.61,-13.5,;17.02,-12.86,;18.07,-14,;17.31,-15.33,;17.79,-16.8,;16.77,-17.95,;15.26,-17.65,;14.78,-16.19,;15.8,-15.03,;12.92,-10.42,;11.61,-11.22,;11.61,-12.76,;10.25,-10.46,;10.25,-8.92,;11.58,-8.14,;11.57,-6.6,;12.89,-5.81,;14.24,-6.58,;15.55,-5.8,;14.26,-8.12,;12.92,-8.89,;8.94,-11.22,;7.59,-10.49,;7.57,-8.95,;6.26,-11.28,;6.26,-12.79,;7.6,-13.56,;4.93,-10.51,;3.59,-11.29,;3.6,-12.83,;2.25,-10.52,;.93,-11.31,;2.24,-8.98,;.91,-8.23,;-.51,-8.85,;-1.56,-7.73,;-.79,-6.39,;-1.27,-4.91,;-.25,-3.76,;1.26,-4.08,;1.74,-5.54,;.72,-6.71,)| Show InChI InChI=1S/C53H71N13O9/c1-4-57-51(74)45-16-10-22-66(45)52(75)40(15-9-21-58-53(55)56)61-47(70)41(23-30(2)3)62-49(72)43(26-33-28-60-39-14-8-6-12-36(33)39)64-48(71)42(24-31-17-19-34(68)20-18-31)63-50(73)44(29-67)65-46(69)37(54)25-32-27-59-38-13-7-5-11-35(32)38/h5-8,11-14,17-20,27-28,30,37,40-45,59-60,67-68H,4,9-10,15-16,21-26,29,54H2,1-3H3,(H,57,74)(H,61,70)(H,62,72)(H,63,73)(H,64,71)(H,65,69)(H4,55,56,58)/t37-,40-,41-,42-,43+,44-,45-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405766
(CHEMBL386525)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)CCc1cccc2ccccc12 Show InChI InChI=1S/C62H77N11O9/c1-4-65-60(80)54-24-14-32-73(54)61(81)49(23-13-31-66-62(63)64)69-56(76)50(33-39(2)3)70-58(78)52(35-44-36-67-48-22-11-10-21-47(44)48)72-57(77)51(34-40-25-28-45(74)29-26-40)71-59(79)53(38-82-37-41-15-6-5-7-16-41)68-55(75)30-27-43-19-12-18-42-17-8-9-20-46(42)43/h5-12,15-22,25-26,28-29,36,39,49-54,67,74H,4,13-14,23-24,27,30-35,37-38H2,1-3H3,(H,65,80)(H,68,75)(H,69,76)(H,70,78)(H,71,79)(H,72,77)(H4,63,64,66)/t49-,50-,51-,52+,53-,54?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405774
(CHEMBL2369800)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6]-c1cccc2ccccc12 Show InChI InChI=1S/C52H68N10O9/c1-4-55-50(70)44-20-12-26-62(44)51(71)39(19-11-25-56-52(53)54)58-46(66)40(27-32(2)3)59-47(67)41(28-33-13-6-5-7-14-33)60-48(68)42(29-34-21-23-37(64)24-22-34)61-49(69)43(31-63)57-45(65)30-36-17-10-16-35-15-8-9-18-38(35)36/h5-10,13-18,21-24,32,39-44,63-64H,4,11-12,19-20,25-31H2,1-3H3,(H,55,70)(H,57,65)(H,58,66)(H,59,67)(H,60,68)(H,61,69)(H4,53,54,56)/t39-,40-,41+,42-,43-,44-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vivo inhibition of leutenising hormone in rats. |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405775
(CHEMBL2369806)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1c[nH]c2ccccc12 |wU:5.4,42.44,31.32,23.24,wD:54.57,12.13,(27.82,-9.83,;26.35,-9.43,;25.96,-7.93,;24.48,-7.54,;23.37,-8.61,;24.07,-6.04,;25.05,-4.85,;24.22,-3.56,;22.72,-3.95,;22.63,-5.49,;21.31,-4.72,;21.33,-3.18,;19.99,-5.49,;19.96,-7.03,;21.28,-7.81,;21.27,-9.35,;22.6,-10.14,;22.56,-11.68,;21.24,-12.43,;23.9,-12.46,;18.64,-4.69,;17.3,-5.49,;17.33,-7.03,;15.98,-4.73,;15.95,-3.19,;17.27,-2.41,;17.27,-.87,;18.62,-3.15,;14.64,-5.5,;13.29,-4.75,;13.29,-3.21,;11.98,-5.53,;11.98,-7.07,;13.32,-7.83,;14.63,-7.04,;15.95,-7.8,;15.99,-9.34,;14.66,-10.12,;13.32,-9.35,;10.63,-4.76,;9.3,-5.55,;9.31,-7.09,;7.93,-4.79,;7.93,-3.24,;9.27,-2.45,;9.25,-.91,;10.6,-.14,;11.93,-.9,;13.26,-.11,;11.94,-2.44,;10.62,-3.22,;6.62,-5.56,;5.27,-4.81,;5.27,-3.27,;3.96,-5.59,;3.96,-7.13,;5.3,-7.89,;2.61,-4.82,;1.26,-5.61,;1.29,-7.16,;-.06,-4.85,;-.09,-3.32,;-1.41,-2.55,;-2.84,-3.19,;-3.87,-2.05,;-3.1,-.71,;-3.59,.76,;-2.57,1.91,;-1.06,1.6,;-.57,.15,;-1.59,-1.03,)| Show InChI InChI=1S/C51H69N11O9/c1-4-54-49(70)43-17-11-25-62(43)50(71)38(16-10-24-55-51(52)53)58-45(66)39(26-31(2)3)59-46(67)40(27-32-12-6-5-7-13-32)60-47(68)41(28-33-18-21-35(64)22-19-33)61-48(69)42(30-63)57-44(65)23-20-34-29-56-37-15-9-8-14-36(34)37/h5-9,12-15,18-19,21-22,29,31,38-43,56,63-64H,4,10-11,16-17,20,23-28,30H2,1-3H3,(H,54,70)(H,57,65)(H,58,66)(H,59,67)(H,60,68)(H,61,69)(H4,52,53,55)/t38-,39-,40+,41-,42-,43-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405779
(CHEMBL411175)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C56H76N10O9/c1-6-59-54(73)48-22-14-28-66(48)55(74)43(21-13-27-60-56(57)58)62-50(69)44(29-35(2)3)63-51(70)45(30-36(4)5)64-52(71)46(31-37-23-25-41(67)26-24-37)65-53(72)47(34-75-33-38-15-8-7-9-16-38)61-49(68)32-40-19-12-18-39-17-10-11-20-42(39)40/h7-12,15-20,23-26,35-36,43-48,67H,6,13-14,21-22,27-34H2,1-5H3,(H,59,73)(H,61,68)(H,62,69)(H,63,70)(H,64,71)(H,65,72)(H4,57,58,60)/t43-,44-,45+,46-,47-,48?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50227965
(CHEMBL414382)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8]-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#6]-c1cccc2ccccc12 Show InChI InChI=1S/C57H78N10O9/c1-6-60-55(74)49-22-14-30-67(49)56(75)44(21-13-29-61-57(58)59)63-51(70)45(31-36(2)3)64-52(71)46(32-37(4)5)65-53(72)47(33-38-23-26-42(68)27-24-38)66-54(73)48(35-76-34-39-15-8-7-9-16-39)62-50(69)28-25-41-19-12-18-40-17-10-11-20-43(40)41/h7-12,15-20,23-24,26-27,36-37,44-49,68H,6,13-14,21-22,25,28-35H2,1-5H3,(H,60,74)(H,62,69)(H,63,70)(H,64,71)(H,65,72)(H,66,73)(H4,58,59,61)/t44-,45-,46+,47-,48-,49?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405773
(CHEMBL2369813)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6]-[#6]-c1cccc2ccccc12 Show InChI InChI=1S/C50H72N10O9/c1-6-53-48(68)42-17-11-25-60(42)49(69)37(16-10-24-54-50(51)52)56-44(64)38(26-30(2)3)57-45(65)39(27-31(4)5)58-46(66)40(28-32-18-21-35(62)22-19-32)59-47(67)41(29-61)55-43(63)23-20-34-14-9-13-33-12-7-8-15-36(33)34/h7-9,12-15,18-19,21-22,30-31,37-42,61-62H,6,10-11,16-17,20,23-29H2,1-5H3,(H,53,68)(H,55,63)(H,56,64)(H,57,65)(H,58,66)(H,59,67)(H4,51,52,54)/t37-,38-,39+,40-,41-,42-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405778
(CHEMBL2369799)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6]-c1cccc2ccccc12 Show InChI InChI=1S/C52H74N10O9/c1-4-55-50(70)44-20-12-26-62(44)51(71)39(19-11-25-56-52(53)54)58-46(66)40(27-32(2)3)59-47(67)41(28-33-13-6-5-7-14-33)60-48(68)42(29-34-21-23-37(64)24-22-34)61-49(69)43(31-63)57-45(65)30-36-17-10-16-35-15-8-9-18-38(35)36/h8-10,15-18,21-24,32-33,39-44,63-64H,4-7,11-14,19-20,25-31H2,1-3H3,(H,55,70)(H,57,65)(H,58,66)(H,59,67)(H,60,68)(H,61,69)(H4,53,54,56)/t39-,40-,41+,42-,43-,44-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
Luteinising hormone inhibiting potency in rats is expressed as negative logarithm of the concentration (antagonist) |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405777
(CHEMBL274609)Show SMILES CCNC(=O)C1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](COCc1ccccc1)NC(=O)Cc1cccc2ccccc12 Show InChI InChI=1S/C63H76N10O9/c1-4-66-61(80)55-24-14-32-73(55)62(81)50(23-13-31-67-63(64)65)69-57(76)51(33-40(2)3)70-59(78)53(36-43-25-28-44-17-8-9-19-46(44)34-43)71-58(77)52(35-41-26-29-48(74)30-27-41)72-60(79)54(39-82-38-42-15-6-5-7-16-42)68-56(75)37-47-21-12-20-45-18-10-11-22-49(45)47/h5-12,15-22,25-30,34,40,50-55,74H,4,13-14,23-24,31-33,35-39H2,1-3H3,(H,66,80)(H,68,75)(H,69,76)(H,70,78)(H,71,77)(H,72,79)(H4,64,65,67)/t50-,51-,52-,53+,54-,55?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405787
(CHEMBL2369808)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC1CCCCC1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1c[nH]c2ccccc12 |wU:5.4,42.44,31.32,23.24,wD:54.57,12.13,(27.82,-9.83,;26.35,-9.43,;25.96,-7.93,;24.48,-7.54,;23.37,-8.61,;24.07,-6.04,;25.05,-4.85,;24.22,-3.56,;22.72,-3.95,;22.63,-5.49,;21.31,-4.72,;21.33,-3.18,;19.99,-5.49,;19.96,-7.03,;21.28,-7.81,;21.27,-9.35,;22.6,-10.14,;22.56,-11.68,;21.24,-12.43,;23.9,-12.46,;18.64,-4.69,;17.3,-5.49,;17.33,-7.03,;15.98,-4.73,;15.95,-3.19,;17.27,-2.41,;17.27,-.87,;18.62,-3.15,;14.64,-5.5,;13.29,-4.75,;13.29,-3.21,;11.98,-5.53,;11.98,-7.07,;13.32,-7.83,;14.63,-7.04,;15.95,-7.8,;15.99,-9.34,;14.66,-10.12,;13.32,-9.35,;10.63,-4.76,;9.3,-5.55,;9.31,-7.09,;7.93,-4.79,;7.93,-3.24,;9.27,-2.45,;9.25,-.91,;10.6,-.14,;11.93,-.9,;13.26,-.11,;11.94,-2.44,;10.62,-3.22,;6.62,-5.56,;5.27,-4.81,;5.27,-3.27,;3.96,-5.59,;3.96,-7.13,;5.3,-7.89,;2.61,-4.82,;1.26,-5.61,;1.29,-7.16,;-.06,-4.85,;-.09,-3.32,;-1.41,-2.55,;-2.84,-3.19,;-3.87,-2.05,;-3.1,-.71,;-3.59,.76,;-2.57,1.91,;-1.06,1.6,;-.57,.15,;-1.59,-1.03,)| Show InChI InChI=1S/C51H75N11O9/c1-4-54-49(70)43-17-11-25-62(43)50(71)38(16-10-24-55-51(52)53)58-45(66)39(26-31(2)3)59-46(67)40(27-32-12-6-5-7-13-32)60-47(68)41(28-33-18-21-35(64)22-19-33)61-48(69)42(30-63)57-44(65)23-20-34-29-56-37-15-9-8-14-36(34)37/h8-9,14-15,18-19,21-22,29,31-32,38-43,56,63-64H,4-7,10-13,16-17,20,23-28,30H2,1-3H3,(H,54,70)(H,57,65)(H,58,66)(H,59,67)(H,60,68)(H,61,69)(H4,52,53,55)/t38-,39-,40+,41-,42-,43-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Gonadotropin-releasing hormone receptor
(Rattus norvegicus) | BDBM50227960
(CHEMBL2369785)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1cccc2ccccc12 Show InChI InChI=1S/C50H73N11O9/c1-6-54-48(69)42-17-11-23-61(42)49(70)37(16-10-22-55-50(52)53)56-44(65)38(24-29(2)3)57-45(66)39(25-30(4)5)58-46(67)40(26-31-18-20-34(63)21-19-31)59-47(68)41(28-62)60-43(64)36(51)27-33-14-9-13-32-12-7-8-15-35(32)33/h7-9,12-15,18-21,29-30,36-42,62-63H,6,10-11,16-17,22-28,51H2,1-5H3,(H,54,69)(H,56,65)(H,57,66)(H,58,67)(H,59,68)(H,60,64)(H4,52,53,55)/t36-,37-,38-,39+,40-,41-,42-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards luteinizing hormone receptor from rat pituitary cells is expressed as negative logarithm of the equilibrium dissoci... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405771
(CHEMBL2369810)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)\[#6]=[#6]\c1cccc2ccccc12 Show InChI InChI=1S/C50H70N10O9/c1-6-53-48(68)42-17-11-25-60(42)49(69)37(16-10-24-54-50(51)52)56-44(64)38(26-30(2)3)57-45(65)39(27-31(4)5)58-46(66)40(28-32-18-21-35(62)22-19-32)59-47(67)41(29-61)55-43(63)23-20-34-14-9-13-33-12-7-8-15-36(33)34/h7-9,12-15,18-23,30-31,37-42,61-62H,6,10-11,16-17,24-29H2,1-5H3,(H,53,68)(H,55,63)(H,56,64)(H,57,65)(H,58,66)(H,59,67)(H4,51,52,54)/b23-20+/t37-,38-,39+,40-,41-,42-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50227966
(CHEMBL2369789)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6]-c1cccc2ccccc12 Show InChI InChI=1S/C49H70N10O9/c1-6-52-47(67)41-17-11-23-59(41)48(68)36(16-10-22-53-49(50)51)55-43(63)37(24-29(2)3)56-44(64)38(25-30(4)5)57-45(65)39(26-31-18-20-34(61)21-19-31)58-46(66)40(28-60)54-42(62)27-33-14-9-13-32-12-7-8-15-35(32)33/h7-9,12-15,18-21,29-30,36-41,60-61H,6,10-11,16-17,22-28H2,1-5H3,(H,52,67)(H,54,62)(H,55,63)(H,56,64)(H,57,65)(H,58,66)(H4,50,51,53)/t36-,37-,38+,39-,40-,41-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50452577
(CHEMBL2369794)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12 |wU:5.4,57.60,39.40,23.24,31.32,wD:51.53,12.13,(30.12,-15.49,;28.63,-15.1,;28.24,-13.6,;26.77,-13.21,;25.67,-14.29,;26.37,-11.71,;27.35,-10.52,;26.51,-9.24,;25.01,-9.62,;24.93,-11.16,;23.62,-10.39,;23.63,-8.86,;22.28,-11.16,;22.25,-12.7,;23.59,-13.49,;23.56,-15.03,;24.88,-15.81,;24.87,-17.35,;23.53,-18.08,;26.19,-18.12,;20.94,-10.36,;19.61,-11.16,;19.62,-12.7,;18.28,-10.39,;18.25,-8.86,;19.58,-8.09,;19.56,-6.55,;20.93,-8.82,;16.95,-11.18,;15.61,-10.43,;15.59,-8.89,;14.27,-11.19,;14.27,-12.73,;15.64,-13.5,;16.96,-12.72,;15.64,-15.04,;12.93,-10.43,;11.61,-11.23,;11.61,-12.77,;10.25,-10.46,;10.25,-8.92,;11.58,-8.14,;11.57,-6.6,;12.89,-5.81,;14.24,-6.58,;15.55,-5.8,;14.26,-8.12,;12.93,-8.89,;8.94,-11.23,;7.59,-10.49,;7.57,-8.95,;6.26,-11.28,;6.26,-12.8,;7.61,-13.57,;4.94,-10.51,;3.59,-11.29,;3.6,-12.83,;2.25,-10.52,;.93,-11.31,;2.24,-8.98,;.91,-8.24,;-.51,-8.86,;-1.56,-7.73,;-.79,-6.39,;-1.27,-4.91,;-.25,-3.76,;1.26,-4.08,;1.74,-5.54,;.72,-6.71,)| Show InChI InChI=1S/C48H72N12O9/c1-6-52-46(68)40-14-10-20-60(40)47(69)35(13-9-19-53-48(50)51)55-42(64)36(21-27(2)3)56-43(65)37(22-28(4)5)57-44(66)38(23-29-15-17-31(62)18-16-29)58-45(67)39(26-61)59-41(63)33(49)24-30-25-54-34-12-8-7-11-32(30)34/h7-8,11-12,15-18,25,27-28,33,35-40,54,61-62H,6,9-10,13-14,19-24,26,49H2,1-5H3,(H,52,68)(H,55,64)(H,56,65)(H,57,66)(H,58,67)(H,59,63)(H4,50,51,53)/t33-,35-,36-,37+,38-,39-,40-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50227964
(CHEMBL2369780)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCCc1c[nH]c2ccccc12 |wU:5.4,39.40,23.24,31.32,wD:51.53,12.13,(33.1,-17.97,;31.61,-17.59,;31.22,-16.08,;29.75,-15.7,;28.64,-16.78,;29.35,-14.19,;30.32,-13,;29.49,-11.72,;27.98,-12.1,;27.91,-13.64,;26.59,-12.87,;26.6,-11.33,;25.25,-13.64,;25.22,-15.18,;26.56,-15.97,;26.54,-17.51,;27.85,-18.29,;27.84,-19.83,;26.51,-20.57,;29.17,-20.6,;23.91,-12.84,;22.58,-13.64,;22.59,-15.18,;21.25,-12.87,;21.21,-11.33,;22.55,-10.56,;22.53,-9.02,;23.9,-11.3,;19.92,-13.66,;18.57,-12.91,;18.55,-11.37,;17.24,-13.68,;17.26,-15.22,;18.58,-15.98,;18.76,-17.51,;19.87,-15.12,;15.89,-12.93,;14.57,-13.71,;14.57,-15.25,;13.22,-12.94,;13.22,-11.4,;14.54,-10.6,;15.89,-11.37,;17.23,-10.6,;17.2,-9.06,;18.52,-8.28,;15.86,-8.29,;14.53,-9.08,;11.9,-13.73,;10.55,-12.97,;10.53,-11.43,;9.22,-13.76,;9.24,-15.28,;10.56,-16.05,;7.89,-12.99,;6.54,-13.77,;6.55,-15.31,;5.21,-13,;3.88,-13.79,;2.54,-13.03,;1.22,-13.8,;1.1,-15.34,;-.38,-15.73,;-1.21,-14.41,;-2.72,-14.16,;-3.23,-12.71,;-2.23,-11.53,;-.73,-11.8,;-.21,-13.25,)| Show InChI InChI=1S/C49H73N11O9/c1-6-52-47(68)41-16-11-23-60(41)48(69)36(15-10-22-53-49(50)51)56-43(64)37(24-29(2)3)57-44(65)38(25-30(4)5)58-45(66)39(26-31-18-20-33(62)21-19-31)59-46(67)40(28-61)55-42(63)17-9-12-32-27-54-35-14-8-7-13-34(32)35/h7-8,13-14,18-21,27,29-30,36-41,54,61-62H,6,9-12,15-17,22-26,28H2,1-5H3,(H,52,68)(H,55,63)(H,56,64)(H,57,65)(H,58,66)(H,59,67)(H4,50,51,53)/t36-,37-,38+,39-,40-,41-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Luteinizing hormone receptor from rat pituitary cells is expressed as negative logarithm of the equilibrium dissoci... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50452578
(CHEMBL2369793)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)\C=C\c1ccc(OC)cc1 |wU:5.4,31.32,45.48,23.24,wD:57.61,12.13,(32.42,-18.05,;30.95,-17.64,;30.56,-16.16,;29.08,-15.75,;27.97,-16.84,;28.67,-14.27,;29.66,-13.08,;28.82,-11.78,;27.33,-12.16,;27.23,-13.7,;25.91,-12.93,;25.94,-11.39,;24.59,-13.7,;24.57,-15.24,;25.88,-16.04,;25.85,-17.57,;27.2,-18.35,;27.17,-19.89,;25.84,-20.65,;28.5,-20.68,;23.24,-12.92,;21.91,-13.7,;21.94,-15.24,;20.58,-12.95,;20.56,-11.39,;21.88,-10.62,;23.22,-11.38,;21.88,-9.08,;19.25,-13.73,;17.9,-12.96,;17.9,-11.42,;16.59,-13.75,;16.59,-15.29,;17.93,-16.04,;19.34,-15.42,;20.37,-16.55,;19.62,-17.89,;20.11,-19.36,;19.09,-20.5,;17.57,-20.21,;17.09,-18.73,;18.09,-17.58,;15.24,-12.99,;13.91,-13.76,;13.92,-15.3,;12.55,-13.02,;12.55,-11.46,;13.88,-10.69,;15.23,-11.45,;16.55,-10.65,;16.54,-9.12,;17.87,-8.35,;15.21,-8.37,;13.86,-9.15,;11.23,-13.8,;9.89,-13.03,;9.89,-11.49,;8.57,-13.83,;8.57,-15.36,;9.92,-16.1,;7.22,-13.06,;5.88,-13.83,;5.91,-15.39,;4.55,-13.08,;3.22,-13.86,;1.89,-13.09,;.58,-13.86,;-.76,-13.11,;-.79,-11.55,;-2.11,-10.8,;-3.43,-11.58,;.56,-10.78,;1.89,-11.55,)| Show InChI InChI=1S/C52H69N11O10/c1-5-55-50(71)44-13-9-25-63(44)51(72)39(12-8-24-56-52(53)54)59-46(67)40(26-31(2)3)60-48(69)42(28-34-29-57-38-11-7-6-10-37(34)38)62-47(68)41(27-33-14-19-35(65)20-15-33)61-49(70)43(30-64)58-45(66)23-18-32-16-21-36(73-4)22-17-32/h6-7,10-11,14-23,29,31,39-44,57,64-65H,5,8-9,12-13,24-28,30H2,1-4H3,(H,55,71)(H,58,66)(H,59,67)(H,60,69)(H,61,70)(H,62,68)(H4,53,54,56)/b23-18+/t39-,40-,41-,42+,43-,44-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50227961
(CHEMBL2369784)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)CCc1c[nH]c2ccccc12 |wU:5.4,39.40,31.32,23.24,wD:51.53,12.13,(30.15,-15.5,;28.66,-15.12,;28.27,-13.61,;26.8,-13.23,;25.69,-14.31,;26.4,-11.72,;27.37,-10.53,;26.54,-9.25,;25.03,-9.63,;24.96,-11.17,;23.64,-10.4,;23.65,-8.86,;22.31,-11.17,;22.27,-12.71,;23.61,-13.5,;23.59,-15.04,;24.9,-15.83,;24.89,-17.37,;23.56,-18.1,;26.22,-18.14,;20.96,-10.37,;19.63,-11.17,;19.64,-12.71,;18.3,-10.4,;18.26,-8.86,;19.6,-8.09,;20.95,-8.83,;19.58,-6.55,;16.97,-11.2,;15.62,-10.44,;15.6,-8.9,;14.29,-11.21,;14.31,-12.75,;15.63,-13.52,;16.92,-12.65,;15.81,-15.04,;12.94,-10.44,;11.62,-11.24,;11.62,-12.78,;10.26,-10.47,;10.26,-8.93,;11.59,-8.15,;11.58,-6.61,;12.91,-5.82,;14.25,-6.59,;15.57,-5.81,;14.27,-8.13,;12.94,-8.9,;8.95,-11.24,;7.6,-10.5,;7.58,-8.96,;6.27,-11.29,;6.27,-12.81,;7.61,-13.58,;4.94,-10.52,;3.59,-11.3,;3.6,-12.84,;2.26,-10.53,;2.25,-8.99,;.91,-8.24,;-.5,-8.89,;-1.53,-7.74,;-.77,-6.39,;-1.25,-4.95,;-.25,-3.82,;1.26,-4.12,;1.74,-5.58,;.72,-6.72,)| Show InChI InChI=1S/C48H71N11O9/c1-6-51-46(67)40-14-10-22-59(40)47(68)35(13-9-21-52-48(49)50)55-42(63)36(23-28(2)3)56-43(64)37(24-29(4)5)57-44(65)38(25-30-15-18-32(61)19-16-30)58-45(66)39(27-60)54-41(62)20-17-31-26-53-34-12-8-7-11-33(31)34/h7-8,11-12,15-16,18-19,26,28-29,35-40,53,60-61H,6,9-10,13-14,17,20-25,27H2,1-5H3,(H,51,67)(H,54,62)(H,55,63)(H,56,64)(H,57,65)(H,58,66)(H4,49,50,52)/t35-,36-,37+,38-,39-,40-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 195 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405765
(CHEMBL2369791)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)c1c[nH]c2ccccc12 |wU:5.4,39.40,31.32,23.24,wD:51.53,12.13,(33.1,-17.97,;31.6,-17.59,;31.22,-16.08,;29.74,-15.69,;28.64,-16.77,;29.35,-14.19,;30.32,-13,;29.49,-11.72,;27.98,-12.1,;27.9,-13.64,;26.59,-12.87,;26.6,-11.33,;25.25,-13.64,;25.22,-15.18,;26.56,-15.97,;26.54,-17.51,;27.85,-18.29,;27.84,-19.83,;26.5,-20.57,;29.17,-20.6,;23.91,-12.84,;22.58,-13.64,;22.59,-15.18,;21.24,-12.87,;21.21,-11.33,;22.55,-10.56,;22.53,-9.02,;23.89,-11.3,;19.92,-13.66,;18.57,-12.9,;18.55,-11.36,;17.23,-13.67,;17.26,-15.21,;18.58,-15.98,;19.86,-15.12,;18.76,-17.51,;15.89,-12.93,;14.57,-13.71,;14.57,-15.25,;13.21,-12.94,;13.21,-11.4,;14.54,-10.59,;15.89,-11.36,;17.22,-10.59,;17.2,-9.06,;18.52,-8.27,;15.86,-8.29,;14.53,-9.08,;11.9,-13.73,;10.55,-12.97,;10.53,-11.43,;9.22,-13.76,;9.24,-15.28,;10.56,-16.05,;7.89,-12.99,;6.54,-13.77,;6.55,-15.31,;5.21,-13,;3.8,-13.64,;2.77,-12.52,;3.53,-11.17,;3.05,-9.73,;4.05,-8.57,;5.56,-8.9,;6.04,-10.36,;5.01,-11.49,)| Show InChI InChI=1S/C46H67N11O9/c1-6-49-44(65)38-14-10-20-57(38)45(66)33(13-9-19-50-46(47)48)52-40(61)34(21-26(2)3)53-41(62)35(22-27(4)5)54-42(63)36(23-28-15-17-29(59)18-16-28)55-43(64)37(25-58)56-39(60)31-24-51-32-12-8-7-11-30(31)32/h7-8,11-12,15-18,24,26-27,33-38,51,58-59H,6,9-10,13-14,19-23,25H2,1-5H3,(H,49,65)(H,52,61)(H,53,62)(H,54,63)(H,55,64)(H,56,60)(H4,47,48,50)/t33-,34-,35+,36-,37-,38-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 204 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50227963
(CHEMBL2369781)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-c1cccc2ccccc12 Show InChI InChI=1S/C48H68N10O9/c1-6-51-46(66)40-17-11-23-58(40)47(67)35(16-10-22-52-48(49)50)53-42(62)36(24-28(2)3)54-43(63)37(25-29(4)5)55-44(64)38(26-30-18-20-32(60)21-19-30)56-45(65)39(27-59)57-41(61)34-15-9-13-31-12-7-8-14-33(31)34/h7-9,12-15,18-21,28-29,35-40,59-60H,6,10-11,16-17,22-27H2,1-5H3,(H,51,66)(H,53,62)(H,54,63)(H,55,64)(H,56,65)(H,57,61)(H4,49,50,52)/t35-,36-,37+,38-,39-,40-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 759 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Luteinizing hormone receptor from rat pituitary cells is expressed as negative logarithm of the equilibrium dissoci... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405768
(CHEMBL2369790)Show SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)Cc1c[nH]c2ccccc12 |wU:5.4,39.40,23.24,31.32,wD:51.53,12.13,(33.09,-17.97,;31.6,-17.58,;31.21,-16.08,;29.74,-15.69,;28.64,-16.77,;29.34,-14.18,;30.31,-13,;29.48,-11.72,;27.97,-12.1,;27.9,-13.64,;26.58,-12.87,;26.59,-11.33,;25.25,-13.64,;25.22,-15.18,;26.55,-15.97,;26.53,-17.51,;27.84,-18.29,;27.83,-19.83,;26.5,-20.57,;29.16,-20.6,;23.9,-12.84,;22.58,-13.64,;22.59,-15.18,;21.24,-12.87,;21.21,-11.33,;22.54,-10.56,;23.89,-11.3,;22.52,-9.02,;19.91,-13.66,;18.57,-12.9,;18.55,-11.36,;17.23,-13.67,;17.25,-15.21,;18.58,-15.98,;19.86,-15.11,;18.76,-17.51,;15.88,-12.92,;14.57,-13.7,;14.57,-15.24,;13.21,-12.93,;13.21,-11.39,;14.54,-10.59,;14.53,-9.07,;15.85,-8.28,;17.2,-9.05,;18.51,-8.27,;17.22,-10.59,;15.88,-11.36,;11.9,-13.72,;10.55,-12.97,;10.53,-11.43,;9.21,-13.76,;9.24,-15.27,;10.56,-16.04,;7.89,-12.99,;6.54,-13.77,;6.55,-15.31,;5.21,-13,;3.88,-13.79,;3.76,-15.33,;2.29,-15.69,;1.45,-14.4,;-.03,-14.12,;-.57,-12.7,;.43,-11.51,;1.93,-11.78,;2.45,-13.22,)| Show InChI InChI=1S/C47H69N11O9/c1-6-50-45(66)39-14-10-20-58(39)46(67)34(13-9-19-51-47(48)49)54-41(62)35(21-27(2)3)55-42(63)36(22-28(4)5)56-43(64)37(23-29-15-17-31(60)18-16-29)57-44(65)38(26-59)53-40(61)24-30-25-52-33-12-8-7-11-32(30)33/h7-8,11-12,15-18,25,27-28,34-39,52,59-60H,6,9-10,13-14,19-24,26H2,1-5H3,(H,50,66)(H,53,61)(H,54,62)(H,55,63)(H,56,64)(H,57,65)(H4,48,49,51)/t34-,35-,36+,37-,38-,39-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50405780
(CHEMBL2369809)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)\[#6]=[#6]\c1cccnc1 Show InChI InChI=1S/C45H67N11O9/c1-6-49-43(64)37-12-9-21-56(37)44(65)32(11-8-20-50-45(46)47)52-39(60)33(22-27(2)3)53-40(61)34(23-28(4)5)54-41(62)35(24-29-13-16-31(58)17-14-29)55-42(63)36(26-57)51-38(59)18-15-30-10-7-19-48-25-30/h7,10,13-19,25,27-28,32-37,57-58H,6,8-9,11-12,20-24,26H2,1-5H3,(H,49,64)(H,51,59)(H,52,60)(H,53,61)(H,54,62)(H,55,63)(H4,46,47,50)/b18-15+/t32-,33-,34+,35-,36-,37-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity for Luteinizing hormone releasing hormone receptor from rat pituitary cells, expressed as negative logarithm of the equilib... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
Lutropin-choriogonadotropic hormone receptor
(Rattus norvegicus) | BDBM50227962
(CHEMBL2369783)Show SMILES [#6]-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6]-[#6]-c1cccnc1 Show InChI InChI=1S/C45H69N11O9/c1-6-49-43(64)37-12-9-21-56(37)44(65)32(11-8-20-50-45(46)47)52-39(60)33(22-27(2)3)53-40(61)34(23-28(4)5)54-41(62)35(24-29-13-16-31(58)17-14-29)55-42(63)36(26-57)51-38(59)18-15-30-10-7-19-48-25-30/h7,10,13-14,16-17,19,25,27-28,32-37,57-58H,6,8-9,11-12,15,18,20-24,26H2,1-5H3,(H,49,64)(H,51,59)(H,52,60)(H,53,61)(H,54,62)(H,55,63)(H4,46,47,50)/t32-,33-,34+,35-,36-,37-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratory
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Luteinizing hormone receptor from rat pituitary cells is expressed as negative logarithm of the equilibrium dissoci... |
J Med Chem 32: 2340-4 (1989)
BindingDB Entry DOI: 10.7270/Q2H70H1B |
More data for this
Ligand-Target Pair | |
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