Found 210 hits Enz. Inhib. hit(s) with all data for entry = 50038780 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276642
(CHEMBL460407 | trans-2-Aminomethyl-5-((2''-methoxy...)Show InChI InChI=1S/C15H22FNO2/c1-18-15-8-5-12(16)9-11(15)3-2-4-13-6-7-14(10-17)19-13/h5,8-9,13-14H,2-4,6-7,10,17H2,1H3/t13-,14+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM30132
(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)Show InChI InChI=1S/C16H24FNO2/c1-19-16-8-5-13(17)11-12(16)3-2-4-14-6-7-15(20-14)9-10-18/h5,8,11,14-15H,2-4,6-7,9-10,18H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM30132
(CHEMBL450907 | tetrahydrofuranyl ethylamine, 15)Show InChI InChI=1S/C16H24FNO2/c1-19-16-8-5-13(17)11-12(16)3-2-4-14-6-7-15(20-14)9-10-18/h5,8,11,14-15H,2-4,6-7,9-10,18H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276645
(2-Aminoethyl-5-(3'-(2''-methoxy-5''-fluorophenyl)-...)Show InChI InChI=1S/C17H26FNO2/c1-20-17-9-6-14(18)12-13(17)4-2-3-5-15-7-8-16(21-15)10-11-19/h6,9,12,15-16H,2-5,7-8,10-11,19H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276593
(CHEMBL462311 | trans-2-(Aminoethyl)-5-(2'-methoxy-...)Show InChI InChI=1S/C15H22FNO2/c1-18-15-7-3-12(16)10-11(15)2-4-13-5-6-14(19-13)8-9-17/h3,7,10,13-14H,2,4-6,8-9,17H2,1H3/t13-,14+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276643
(CHEMBL459367 | cis-2-Aminomethyl-5-((2''-methoxy-5...)Show InChI InChI=1S/C15H22FNO2/c1-18-15-8-5-12(16)9-11(15)3-2-4-13-6-7-14(10-17)19-13/h5,8-9,13-14H,2-4,6-7,10,17H2,1H3/t13-,14-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276591
(CHEMBL511500 | trans-2-(Aminomethyl)-5-(2'-methoxy...)Show InChI InChI=1S/C14H20FNO2/c1-17-14-7-3-11(15)8-10(14)2-4-12-5-6-13(9-16)18-12/h3,7-8,12-13H,2,4-6,9,16H2,1H3/t12-,13+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276644
(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)Show InChI InChI=1S/C16H24FNO2/c1-19-16-9-6-13(17)10-12(16)4-2-3-5-14-7-8-15(11-18)20-14/h6,9-10,14-15H,2-5,7-8,11,18H2,1H3/t14-,15+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276460
(2-(Aminomethyl)-5-(1'-naphthethyl)tetrahydrofuran ...)Show InChI InChI=1S/C17H21NO/c18-12-16-11-10-15(19-16)9-8-14-6-3-5-13-4-1-2-7-17(13)14/h1-7,15-16H,8-12,18H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276641
(CHEMBL460406 | cis-2-(Aminoethyl)-5-(2'-methoxy-5'...)Show InChI InChI=1S/C15H22FNO2/c1-18-15-7-3-12(16)10-11(15)2-4-13-5-6-14(19-13)8-9-17/h3,7,10,13-14H,2,4-6,8-9,17H2,1H3/t13-,14-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 19.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276589
(CHEMBL456222 | trans-2-Aminoethyl-5-(2'-methoxy-5'...)Show InChI InChI=1S/C14H20FNO2/c1-17-14-5-2-11(15)8-10(14)9-13-4-3-12(18-13)6-7-16/h2,5,8,12-13H,3-4,6-7,9,16H2,1H3/t12-,13-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276590
(CHEMBL450769 | cis-2-Aminoethyl-5-(2'-methoxy-5'-f...)Show InChI InChI=1S/C14H20FNO2/c1-17-14-5-2-11(15)8-10(14)9-13-4-3-12(18-13)6-7-16/h2,5,8,12-13H,3-4,6-7,9,16H2,1H3/t12-,13+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276592
(CHEMBL456223 | cis-2-(Aminomethyl)-5-(2'-methoxy-5...)Show InChI InChI=1S/C14H20FNO2/c1-17-14-7-3-11(15)8-10(14)2-4-12-5-6-13(9-16)18-12/h3,7-8,12-13H,2,4-6,9,16H2,1H3/t12-,13-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276420
(2-Aminomethyl-5-(phenyl)tetrahydrofuran | CHEMBL45...)Show InChI InChI=1S/C11H15NO/c12-8-10-6-7-11(13-10)9-4-2-1-3-5-9/h1-5,10-11H,6-8,12H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276457
(2-(Aminomethyl)-5-(2'-naphthyl)tetrahydrofuran | C...)Show InChI InChI=1S/C15H17NO/c16-10-14-7-8-15(17-14)13-6-5-11-3-1-2-4-12(11)9-13/h1-6,9,14-15H,7-8,10,16H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276459
(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)Show InChI InChI=1S/C13H19NO/c14-10-13-9-8-12(15-13)7-6-11-4-2-1-3-5-11/h1-5,12-13H,6-10,14H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276754
(2-Aminoethyl-5-(2'-methoxy-1'-naphthethyl)tetrahyd...)Show InChI InChI=1S/C19H25NO2/c1-21-19-11-6-14-4-2-3-5-17(14)18(19)10-9-15-7-8-16(22-15)12-13-20/h2-6,11,15-16H,7-10,12-13,20H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276753
(2-Aminoethyl-5-(4'-methoxy-1'-naphthethyl)tetrahyd...)Show InChI InChI=1S/C19H25NO2/c1-21-19-11-7-14(17-4-2-3-5-18(17)19)6-8-15-9-10-16(22-15)12-13-20/h2-5,7,11,15-16H,6,8-10,12-13,20H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276588
(CHEMBL450987 | cis-2-Aminomethyl-5-(2'-methoxy-5'-...)Show InChI InChI=1S/C13H18FNO2/c1-16-13-5-2-10(14)6-9(13)7-11-3-4-12(8-15)17-11/h2,5-6,11-12H,3-4,7-8,15H2,1H3/t11-,12+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 151 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276458
(2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran | C...)Show InChI InChI=1S/C15H17NO/c16-10-12-8-9-15(17-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,12,15H,8-10,16H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 174 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276587
(CHEMBL456221 | trans-2-Aminomethyl-5-(2'-methoxy-5...)Show InChI InChI=1S/C13H18FNO2/c1-16-13-5-2-10(14)6-9(13)7-11-3-4-12(8-15)17-11/h2,5-6,11-12H,3-4,7-8,15H2,1H3/t11-,12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 192 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50084717
((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 276 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50084717
((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 371 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human DAT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276590
(CHEMBL450769 | cis-2-Aminoethyl-5-(2'-methoxy-5'-f...)Show InChI InChI=1S/C14H20FNO2/c1-17-14-5-2-11(15)8-10(14)9-13-4-3-12(18-13)6-7-16/h2,5,8,12-13H,3-4,6-7,9,16H2,1H3/t12-,13+/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 455 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50276457
(2-(Aminomethyl)-5-(2'-naphthyl)tetrahydrofuran | C...)Show InChI InChI=1S/C15H17NO/c16-10-14-7-8-15(17-14)13-6-5-11-3-1-2-4-12(11)9-13/h1-6,9,14-15H,7-8,10,16H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 512 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human DAT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276461
(2-Aminomethyl-5-(pentafluorophenethyl)tetrahydrofu...)Show InChI InChI=1S/C13H14F5NO/c14-9-8(10(15)12(17)13(18)11(9)16)4-3-6-1-2-7(5-19)20-6/h6-7H,1-5,19H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 634 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276508
(2-Aminoethyl-5-(4'-fluoro-3'-methylphenethyl)tetra...)Show InChI InChI=1S/C15H22FNO/c1-11-10-12(3-7-15(11)16)2-4-13-5-6-14(18-13)8-9-17/h3,7,10,13-14H,2,4-6,8-9,17H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 688 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276508
(2-Aminoethyl-5-(4'-fluoro-3'-methylphenethyl)tetra...)Show InChI InChI=1S/C15H22FNO/c1-11-10-12(3-7-15(11)16)2-4-13-5-6-14(18-13)8-9-17/h3,7,10,13-14H,2,4-6,8-9,17H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 882 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50276420
(2-Aminomethyl-5-(phenyl)tetrahydrofuran | CHEMBL45...)Show InChI InChI=1S/C11H15NO/c12-8-10-6-7-11(13-10)9-4-2-1-3-5-9/h1-5,10-11H,6-8,12H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 916 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human DAT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276421
(2-Aminomethyl-5-(p-chlorophenyl)tetrahydrofuran | ...)Show InChI InChI=1S/C11H14ClNO/c12-9-3-1-8(2-4-9)11-6-5-10(7-13)14-11/h1-4,10-11H,5-7,13H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276421
(2-Aminomethyl-5-(p-chlorophenyl)tetrahydrofuran | ...)Show InChI InChI=1S/C11H14ClNO/c12-9-3-1-8(2-4-9)11-6-5-10(7-13)14-11/h1-4,10-11H,5-7,13H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276454
(2-Aminomethyl-5-(p-bromophenyl)tetrahydrofuran | C...)Show InChI InChI=1S/C11H14BrNO/c12-9-3-1-8(2-4-9)11-6-5-10(7-13)14-11/h1-4,10-11H,5-7,13H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50084717
((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)Show SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1C(=O)Oc1ccccc1)N2C |THB:2:4:20:6.7| Show InChI InChI=1S/C17H21NO4/c1-18-11-8-9-14(18)15(17(20)21-2)13(10-11)16(19)22-12-6-4-3-5-7-12/h3-7,11,13-15H,8-10H2,1-2H3/t11?,13-,14?,15-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276458
(2-(Aminomethyl)-5-(1'-naphthyl)tetrahydrofuran | C...)Show InChI InChI=1S/C15H17NO/c16-10-12-8-9-15(17-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,12,15H,8-10,16H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50276459
(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)Show InChI InChI=1S/C13H19NO/c14-10-13-9-8-12(15-13)7-6-11-4-2-1-3-5-11/h1-5,12-13H,6-10,14H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human DAT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276589
(CHEMBL456222 | trans-2-Aminoethyl-5-(2'-methoxy-5'...)Show InChI InChI=1S/C14H20FNO2/c1-17-14-5-2-11(15)8-10(14)9-13-4-3-12(18-13)6-7-16/h2,5,8,12-13H,3-4,6-7,9,16H2,1H3/t12-,13-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276513
(CHEMBL512736 | trans-2-Aminoethyl-5-(2'-methoxy-5'...)Show InChI InChI=1S/C13H18FNO2/c1-16-12-4-2-9(14)8-11(12)13-5-3-10(17-13)6-7-15/h2,4,8,10,13H,3,5-7,15H2,1H3/t10-,13-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276455
(2-Aminomethyl-5-(p-methoxyphenyl)tetrahydrofuran |...)Show InChI InChI=1S/C12H17NO2/c1-14-10-4-2-9(3-5-10)12-7-6-11(8-13)15-12/h2-5,11-12H,6-8,13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 2.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276461
(2-Aminomethyl-5-(pentafluorophenethyl)tetrahydrofu...)Show InChI InChI=1S/C13H14F5NO/c14-9-8(10(15)12(17)13(18)11(9)16)4-3-6-1-2-7(5-19)20-6/h6-7H,1-5,19H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276644
(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)Show InChI InChI=1S/C16H24FNO2/c1-19-16-9-6-13(17)10-12(16)4-2-3-5-14-7-8-15(11-18)20-14/h6,9-10,14-15H,2-5,7-8,11,18H2,1H3/t14-,15+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276593
(CHEMBL462311 | trans-2-(Aminoethyl)-5-(2'-methoxy-...)Show InChI InChI=1S/C15H22FNO2/c1-18-15-7-3-12(16)10-11(15)2-4-13-5-6-14(19-13)8-9-17/h3,7,10,13-14H,2,4-6,8-9,17H2,1H3/t13-,14+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276459
(2-(Aminomethyl)-5-phenethyltetrahydrofuran | CHEMB...)Show InChI InChI=1S/C13H19NO/c14-10-13-9-8-12(15-13)7-6-11-4-2-1-3-5-11/h1-5,12-13H,6-10,14H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276420
(2-Aminomethyl-5-(phenyl)tetrahydrofuran | CHEMBL45...)Show InChI InChI=1S/C11H15NO/c12-8-10-6-7-11(13-10)9-4-2-1-3-5-9/h1-5,10-11H,6-8,12H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50276645
(2-Aminoethyl-5-(3'-(2''-methoxy-5''-fluorophenyl)-...)Show InChI InChI=1S/C17H26FNO2/c1-20-17-9-6-14(18)12-13(17)4-2-3-5-15-7-8-16(21-15)10-11-19/h6,9,12,15-16H,2-5,7-8,10-11,19H2,1H3 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human DAT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276507
(2-(2'-Aminoethyl)-5-benzyltetrahydrofuran | CHEMBL...)Show InChI InChI=1S/C13H19NO/c14-9-8-12-6-7-13(15-12)10-11-4-2-1-3-5-11/h1-5,12-13H,6-10,14H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 3.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50276644
(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)Show InChI InChI=1S/C16H24FNO2/c1-19-16-9-6-13(17)10-12(16)4-2-3-5-14-7-8-15(11-18)20-14/h6,9-10,14-15H,2-5,7-8,11,18H2,1H3/t14-,15+/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human DAT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276645
(2-Aminoethyl-5-(3'-(2''-methoxy-5''-fluorophenyl)-...)Show InChI InChI=1S/C17H26FNO2/c1-20-17-9-6-14(18)12-13(17)4-2-3-5-15-7-8-16(21-15)10-11-19/h6,9,12,15-16H,2-5,7-8,10-11,19H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50276456
(2-Aminomethyl-5-(p-t-butylphenyl)tetrahydrofuran |...)Show InChI InChI=1S/C15H23NO/c1-15(2,3)12-6-4-11(5-7-12)14-9-8-13(10-16)17-14/h4-7,13-14H,8-10,16H2,1-3H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human NET expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50276506
(2-(Aminomethyl)-5-(3'-pyridinylethyl)tetrahydrofur...)Show InChI InChI=1S/C12H18N2O/c13-8-12-6-5-11(15-12)4-3-10-2-1-7-14-9-10/h1-2,7,9,11-12H,3-6,8,13H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 4.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human SERT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50276643
(CHEMBL459367 | cis-2-Aminomethyl-5-((2''-methoxy-5...)Show InChI InChI=1S/C15H22FNO2/c1-18-15-8-5-12(16)9-11(15)3-2-4-13-6-7-14(10-17)19-13/h5,8-9,13-14H,2-4,6-7,10,17H2,1H3/t13-,14-/m1/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Human BioMolecular Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]RTI55 from human DAT expressed in HEK cells |
Bioorg Med Chem 17: 2047-68 (2009)
Article DOI: 10.1016/j.bmc.2009.01.023 BindingDB Entry DOI: 10.7270/Q2057GV0 |
More data for this Ligand-Target Pair | |