Compile Data Set for Download or QSAR

Found 90 hits Enz. Inhib. hit(s) with all data for entry = 50039522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379402 (CHEMBL2012014) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)c1 Show InChI InChI=1S/C17H14ClN3O/c18-12-1-5-15(6-2-12)22-16-7-3-14(4-8-16)21-17-11-13(19)9-10-20-17/h1-11H,(H3,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379423 (CHEMBL2012038) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)26-14-7-5-13(6-8-14)25-12-3-1-11(2-4-12)23-16-22-10-9-15(21)24-16/h1-10H,(H3,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379401 (CHEMBL2011946) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)c1 Show InChI InChI=1S/C17H14ClN3O/c18-12-1-5-16(6-2-12)22-17-7-3-14(4-8-17)21-15-9-13(19)10-20-11-15/h1-11,21H,19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379398 (CHEMBL2011952) Show SMILES Nc1nccc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-15-9-10-19-16(18)21-15/h1-10H,(H3,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379396 (CHEMBL2011950) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-19-10-9-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379416 (CHEMBL2012030) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(cc3)C3CC3)cc2)n1 Show InChI InChI=1S/C19H18N4O/c20-18-11-12-21-19(23-18)22-15-5-9-17(10-6-15)24-16-7-3-14(4-8-16)13-1-2-13/h3-13H,1-2H2,(H3,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379410 (CHEMBL2012023) Show SMILES CN(c1ccc(Cl)cc1)c1ccc(Nc2nccc(N)n2)cc1 Show InChI InChI=1S/C17H16ClN5/c1-23(14-6-2-12(18)3-7-14)15-8-4-13(5-9-15)21-17-20-11-10-16(19)22-17/h2-11H,1H3,(H3,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379391 (CHEMBL2012037) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)n1 Show InChI InChI=1S/C17H13F3N4O/c18-17(19,20)11-1-5-13(6-2-11)25-14-7-3-12(4-8-14)23-16-22-10-9-15(21)24-16/h1-10H,(H3,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379425 (CHEMBL2012040) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1 Show InChI InChI=1S/C16H13FN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-10-19-9-15(18)21-16/h1-10H,(H3,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379415 (CHEMBL2012029) Show SMILES Cc1ccc(Oc2ccc(Nc3nccc(N)n3)cc2)cc1 Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-19-11-10-16(18)21-17/h2-11H,1H3,(H3,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379418 (CHEMBL2012032) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(cc3)C#N)cc2)n1 Show InChI InChI=1S/C17H13N5O/c18-11-12-1-5-14(6-2-12)23-15-7-3-13(4-8-15)21-17-20-10-9-16(19)22-17/h1-10H,(H3,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379413 (CHEMBL2012027) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccccc3Cl)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-13-3-1-2-4-14(13)22-12-7-5-11(6-8-12)20-16-19-10-9-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379414 (CHEMBL2012028) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1 Show InChI InChI=1S/C16H13FN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-19-10-9-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379426 (CHEMBL2012041) Show SMILES Cc1ccc(Oc2ccc(Nc3cncc(N)n3)cc2)cc1 Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-11-19-10-16(18)21-17/h2-11H,1H3,(H3,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379393 (CHEMBL2011947) Show SMILES Nc1ncnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C15H12ClN5O/c16-10-1-5-12(6-2-10)22-13-7-3-11(4-8-13)20-15-19-9-18-14(17)21-15/h1-9H,(H3,17,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379427 (CHEMBL2012044) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)n1 Show InChI InChI=1S/C17H13F3N4O/c18-17(19,20)11-1-5-13(6-2-11)25-14-7-3-12(4-8-14)23-16-10-22-9-15(21)24-16/h1-10H,(H3,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379405 (CHEMBL2012017) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-10-19-9-15(18)21-16/h1-10H,(H3,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of dofetilide from human ERG				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379393 (CHEMBL2011947) Show SMILES Nc1ncnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C15H12ClN5O/c16-10-1-5-12(6-2-10)22-13-7-3-11(4-8-13)20-15-19-9-18-14(17)21-15/h1-9H,(H3,17,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by manual whole cell patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379389 (CHEMBL2010816) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)26-14-7-5-13(6-8-14)25-12-3-1-11(2-4-12)23-16-10-22-9-15(21)24-16/h1-10H,(H3,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379423 (CHEMBL2012038) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)26-14-7-5-13(6-8-14)25-12-3-1-11(2-4-12)23-16-22-10-9-15(21)24-16/h1-10H,(H3,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379427 (CHEMBL2012044) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)n1 Show InChI InChI=1S/C17H13F3N4O/c18-17(19,20)11-1-5-13(6-2-11)25-14-7-3-12(4-8-14)23-16-10-22-9-15(21)24-16/h1-10H,(H3,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379393 (CHEMBL2011947) Show SMILES Nc1ncnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C15H12ClN5O/c16-10-1-5-12(6-2-10)22-13-7-3-11(4-8-13)20-15-19-9-18-14(17)21-15/h1-9H,(H3,17,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by manual whole cell patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379413 (CHEMBL2012027) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccccc3Cl)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-13-3-1-2-4-14(13)22-12-7-5-11(6-8-12)20-16-19-10-9-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379426 (CHEMBL2012041) Show SMILES Cc1ccc(Oc2ccc(Nc3cncc(N)n3)cc2)cc1 Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-11-19-10-16(18)21-17/h2-11H,1H3,(H3,18,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379425 (CHEMBL2012040) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1 Show InChI InChI=1S/C16H13FN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-10-19-9-15(18)21-16/h1-10H,(H3,18,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379396 (CHEMBL2011950) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-19-10-9-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379427 (CHEMBL2012044) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)n1 Show InChI InChI=1S/C17H13F3N4O/c18-17(19,20)11-1-5-13(6-2-11)25-14-7-3-12(4-8-14)23-16-10-22-9-15(21)24-16/h1-10H,(H3,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379425 (CHEMBL2012040) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1 Show InChI InChI=1S/C16H13FN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-10-19-9-15(18)21-16/h1-10H,(H3,18,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379396 (CHEMBL2011950) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-19-10-9-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379428 (CHEMBL2012039) Show SMILES Nc1cncc(Nc2ccc(Oc3ccccc3)cc2)n1 Show InChI InChI=1S/C16H14N4O/c17-15-10-18-11-16(20-15)19-12-6-8-14(9-7-12)21-13-4-2-1-3-5-13/h1-11H,(H3,17,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379415 (CHEMBL2012029) Show SMILES Cc1ccc(Oc2ccc(Nc3nccc(N)n3)cc2)cc1 Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-19-11-10-16(18)21-17/h2-11H,1H3,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379405 (CHEMBL2012017) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-10-19-9-15(18)21-16/h1-10H,(H3,18,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379405 (CHEMBL2012017) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-10-19-9-15(18)21-16/h1-10H,(H3,18,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379414 (CHEMBL2012028) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1 Show InChI InChI=1S/C16H13FN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-19-10-9-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379389 (CHEMBL2010816) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)26-14-7-5-13(6-8-14)25-12-3-1-11(2-4-12)23-16-10-22-9-15(21)24-16/h1-10H,(H3,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by manual whole cell patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379426 (CHEMBL2012041) Show SMILES Cc1ccc(Oc2ccc(Nc3cncc(N)n3)cc2)cc1 Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-11-19-10-16(18)21-17/h2-11H,1H3,(H3,18,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379423 (CHEMBL2012038) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)26-14-7-5-13(6-8-14)25-12-3-1-11(2-4-12)23-16-22-10-9-15(21)24-16/h1-10H,(H3,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379414 (CHEMBL2012028) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1 Show InChI InChI=1S/C16H13FN4O/c17-11-1-5-13(6-2-11)22-14-7-3-12(4-8-14)20-16-19-10-9-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379418 (CHEMBL2012032) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(cc3)C#N)cc2)n1 Show InChI InChI=1S/C17H13N5O/c18-11-12-1-5-14(6-2-12)23-15-7-3-13(4-8-15)21-17-20-10-9-16(19)22-17/h1-10H,(H3,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379389 (CHEMBL2010816) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)26-14-7-5-13(6-8-14)25-12-3-1-11(2-4-12)23-16-10-22-9-15(21)24-16/h1-10H,(H3,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379391 (CHEMBL2012037) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)n1 Show InChI InChI=1S/C17H13F3N4O/c18-17(19,20)11-1-5-13(6-2-11)25-14-7-3-12(4-8-14)23-16-22-10-9-15(21)24-16/h1-10H,(H3,21,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379390 (CHEMBL2012042) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(cc3)C3CC3)cc2)n1 Show InChI InChI=1S/C19H18N4O/c20-18-11-21-12-19(23-18)22-15-5-9-17(10-6-15)24-16-7-3-14(4-8-16)13-1-2-13/h3-13H,1-2H2,(H3,20,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379402 (CHEMBL2012014) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)c1 Show InChI InChI=1S/C17H14ClN3O/c18-12-1-5-15(6-2-12)22-16-7-3-14(4-8-16)21-17-11-13(19)9-10-20-17/h1-11H,(H3,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379416 (CHEMBL2012030) Show SMILES Nc1ccnc(Nc2ccc(Oc3ccc(cc3)C3CC3)cc2)n1 Show InChI InChI=1S/C19H18N4O/c20-18-11-12-21-19(23-18)22-15-5-9-17(10-6-15)24-16-7-3-14(4-8-16)13-1-2-13/h3-13H,1-2H2,(H3,20,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50379393 (CHEMBL2011947) Show SMILES Nc1ncnc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1 Show InChI InChI=1S/C15H12ClN5O/c16-10-1-5-12(6-2-10)22-13-7-3-11(4-8-13)20-15-19-9-18-14(17)21-15/h1-9H,(H3,17,18,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG by PatchXpress volatage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379389 (CHEMBL2010816) Show SMILES Nc1cncc(Nc2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 Show InChI InChI=1S/C17H13F3N4O2/c18-17(19,20)26-14-7-5-13(6-8-14)25-12-3-1-11(2-4-12)23-16-10-22-9-15(21)24-16/h1-10H,(H3,21,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by manual whole cell patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379415 (CHEMBL2012029) Show SMILES Cc1ccc(Oc2ccc(Nc3nccc(N)n3)cc2)cc1 Show InChI InChI=1S/C17H16N4O/c1-12-2-6-14(7-3-12)22-15-8-4-13(5-9-15)20-17-19-11-10-16(18)21-17/h2-11H,1H3,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379412 (CHEMBL2012026) Show SMILES Nc1ccnc(Nc2ccc(Oc3cccc(Cl)c3)cc2)n1 Show InChI InChI=1S/C16H13ClN4O/c17-11-2-1-3-14(10-11)22-13-6-4-12(5-7-13)20-16-19-9-8-15(18)21-16/h1-10H,(H3,18,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50379428 (CHEMBL2012039) Show SMILES Nc1cncc(Nc2ccc(Oc3ccccc3)cc2)n1 Show InChI InChI=1S/C16H14N4O/c17-15-10-18-11-16(20-15)19-12-6-8-14(9-7-12)21-13-4-2-1-3-5-13/h1-11H,(H3,17,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.5 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50379410 (CHEMBL2012023) Show SMILES CN(c1ccc(Cl)cc1)c1ccc(Nc2nccc(N)n2)cc1 Show InChI InChI=1S/C17H16ClN5/c1-23(14-6-2-12(18)3-7-14)15-8-4-13(5-9-15)21-17-20-11-10-16(19)22-17/h2-11H,1H3,(H3,19,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human partially inactivated NaV 1.7 channel expressed in HEK293 cells by PatchXpress voltage patch clamp assay				Bioorg Med Chem Lett 22: 2033-42 (2012) Article DOI: 10.1016/j.bmcl.2012.01.023 BindingDB Entry DOI: 10.7270/Q2S183H3
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 90 total )  |  Next  |  Last  >>

Jump to: