Found 23 hits Enz. Inhib. hit(s) with all data for entry = 50041827 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50416474
(CHEMBL1209710)Show SMILES C[C@H]1CN(CCN1C)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-16-13-25(12-11-24(16)2)23(27)19-14-26-20(17-7-4-3-5-8-17)15-28-21-10-6-9-18(19)22(21)26/h6,9-10,14,16-17,20H,3-5,7-8,11-13,15H2,1-2H3/t16-,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human cannabinoid CB2 receptor expressed in insect Sf9 cells |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416474
(CHEMBL1209710)Show SMILES C[C@H]1CN(CCN1C)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-16-13-25(12-11-24(16)2)23(27)19-14-26-20(17-7-4-3-5-8-17)15-28-21-10-6-9-18(19)22(21)26/h6,9-10,14,16-17,20H,3-5,7-8,11-13,15H2,1-2H3/t16-,20-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human cannabinoid CB1 receptor expressed in insect Sf9 cells |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(Homo sapiens (Human)) | BDBM50416463
(CHEMBL1209573)Show SMILES CCN1CCN(CC1)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-2-24-11-13-25(14-12-24)23(27)19-15-26-20(17-7-4-3-5-8-17)16-28-21-10-6-9-18(19)22(21)26/h6,9-10,15,17,20H,2-5,7-8,11-14,16H2,1H3/t20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.98 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human cannabinoid CB2 receptor expressed in insect Sf9 cells |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416463
(CHEMBL1209573)Show SMILES CCN1CCN(CC1)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-2-24-11-13-25(14-12-24)23(27)19-15-26-20(17-7-4-3-5-8-17)16-28-21-10-6-9-18(19)22(21)26/h6,9-10,15,17,20H,2-5,7-8,11-14,16H2,1H3/t20-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [3H]CP-55940 from human cannabinoid CB1 receptor expressed in insect Sf9 cells |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416466
(CHEMBL1209576)Show SMILES CN1CCN(CC1)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C22H29N3O2/c1-23-10-12-24(13-11-23)22(26)18-14-25-19(16-6-3-2-4-7-16)15-27-20-9-5-8-17(18)21(20)25/h5,8-9,14,16,19H,2-4,6-7,10-13,15H2,1H3/t19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416467
(CHEMBL1209643)Show SMILES O=C(N1CCNCC1)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C21H27N3O2/c25-21(23-11-9-22-10-12-23)17-13-24-18(15-5-2-1-3-6-15)14-26-19-8-4-7-16(17)20(19)24/h4,7-8,13,15,18,22H,1-3,5-6,9-12,14H2/t18-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416468
(CHEMBL1209644)Show SMILES CCN1[C@@H](C)CN(C[C@H]1C)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C25H35N3O2/c1-4-27-17(2)13-26(14-18(27)3)25(29)21-15-28-22(19-9-6-5-7-10-19)16-30-23-12-8-11-20(21)24(23)28/h8,11-12,15,17-19,22H,4-7,9-10,13-14,16H2,1-3H3/t17-,18+,22-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 3.98 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416469
(CHEMBL1209645)Show SMILES C[C@H]1CN(C[C@@H](C)N1C)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C24H33N3O2/c1-16-12-26(13-17(2)25(16)3)24(28)20-14-27-21(18-8-5-4-6-9-18)15-29-22-11-7-10-19(20)23(22)27/h7,10-11,14,16-18,21H,4-6,8-9,12-13,15H2,1-3H3/t16-,17+,21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.31 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416470
(CHEMBL1209646)Show SMILES C[C@H]1CN(C[C@@H](C)N1)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-15-11-25(12-16(2)24-15)23(27)19-13-26-20(17-7-4-3-5-8-17)14-28-21-10-6-9-18(19)22(21)26/h6,9-10,13,15-17,20,24H,3-5,7-8,11-12,14H2,1-2H3/t15-,16+,20-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416471
(CHEMBL1209647)Show SMILES CCN1[C@@H](C)CN(C[C@H]1C)C(=O)c1cn(CC2CCCCC2)c2c(OC)cccc12 |r| Show InChI InChI=1S/C25H37N3O2/c1-5-28-18(2)14-27(15-19(28)3)25(29)22-17-26(16-20-10-7-6-8-11-20)24-21(22)12-9-13-23(24)30-4/h9,12-13,17-20H,5-8,10-11,14-16H2,1-4H3/t18-,19+ | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416472
(CHEMBL1209708)Show SMILES COc1cccc2c(cn(CC3CCCCC3)c12)C(=O)N1C[C@H](C)N(C)[C@H](C)C1 |r| Show InChI InChI=1S/C24H35N3O2/c1-17-13-27(14-18(2)25(17)3)24(28)21-16-26(15-19-9-6-5-7-10-19)23-20(21)11-8-12-22(23)29-4/h8,11-12,16-19H,5-7,9-10,13-15H2,1-4H3/t17-,18+ | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 25.1 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416473
(CHEMBL1209709)Show SMILES COc1cccc2c(cn(CC3CCCCC3)c12)C(=O)N1CCN(C)[C@@H](C)C1 |r| Show InChI InChI=1S/C23H33N3O2/c1-17-14-25(13-12-24(17)2)23(27)20-16-26(15-18-8-5-4-6-9-18)22-19(20)10-7-11-21(22)28-3/h7,10-11,16-18H,4-6,8-9,12-15H2,1-3H3/t17-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 25.1 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416474
(CHEMBL1209710)Show SMILES C[C@H]1CN(CCN1C)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-16-13-25(12-11-24(16)2)23(27)19-14-26-20(17-7-4-3-5-8-17)15-28-21-10-6-9-18(19)22(21)26/h6,9-10,14,16-17,20H,3-5,7-8,11-13,15H2,1-2H3/t16-,20-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 15.8 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416475
(CHEMBL1209807)Show SMILES COCCN1[C@@H](C)CN(C[C@H]1C)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C26H37N3O3/c1-18-14-27(15-19(2)28(18)12-13-31-3)26(30)22-16-29-23(20-8-5-4-6-9-20)17-32-24-11-7-10-21(22)25(24)29/h7,10-11,16,18-20,23H,4-6,8-9,12-15,17H2,1-3H3/t18-,19+,23-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416476
(CHEMBL1209806)Show SMILES C[C@H]1CN(C[C@@H](C)N1CCO)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C25H35N3O3/c1-17-13-26(14-18(2)27(17)11-12-29)25(30)21-15-28-22(19-7-4-3-5-8-19)16-31-23-10-6-9-20(21)24(23)28/h6,9-10,15,17-19,22,29H,3-5,7-8,11-14,16H2,1-2H3/t17-,18+,22-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6.31 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416477
(CHEMBL1209805)Show SMILES C[C@H]1CNC[C@@H](C)N1C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-15-11-24-12-16(2)26(15)23(27)19-13-25-20(17-7-4-3-5-8-17)14-28-21-10-6-9-18(19)22(21)25/h6,9-10,13,15-17,20,24H,3-5,7-8,11-12,14H2,1-2H3/t15-,16+,20-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 794 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416478
(CHEMBL1209712)Show SMILES C[C@H]1CN(C)C[C@@H](C)N1C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C24H33N3O2/c1-16-12-25(3)13-17(2)27(16)24(28)20-14-26-21(18-8-5-4-6-9-18)15-29-22-11-7-10-19(20)23(22)26/h7,10-11,14,16-18,21H,4-6,8-9,12-13,15H2,1-3H3/t16-,17+,21-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 63.1 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416479
(CHEMBL1209711)Show SMILES C[C@H]1CN(CCN1)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C22H29N3O2/c1-15-12-24(11-10-23-15)22(26)18-13-25-19(16-6-3-2-4-7-16)14-27-20-9-5-8-17(18)21(20)25/h5,8-9,13,15-16,19,23H,2-4,6-7,10-12,14H2,1H3/t15-,19-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416465
(CHEMBL1209575)Show SMILES CCN1CCN(CC1)C(=O)c1cn(CC2CCCCC2)c2c(OC)cccc12 Show InChI InChI=1S/C23H33N3O2/c1-3-24-12-14-25(15-13-24)23(27)20-17-26(16-18-8-5-4-6-9-18)22-19(20)10-7-11-21(22)28-2/h7,10-11,17-18H,3-6,8-9,12-16H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416464
(CHEMBL1209574)Show SMILES CCN1CCN(CC1)C(=O)c1cn2[C@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-2-24-11-13-25(14-12-24)23(27)19-15-26-20(17-7-4-3-5-8-17)16-28-21-10-6-9-18(19)22(21)26/h6,9-10,15,17,20H,2-5,7-8,11-14,16H2,1H3/t20-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416463
(CHEMBL1209573)Show SMILES CCN1CCN(CC1)C(=O)c1cn2[C@@H](COc3cccc1c23)C1CCCCC1 |r| Show InChI InChI=1S/C23H31N3O2/c1-2-24-11-13-25(14-12-24)23(27)19-15-26-20(17-7-4-3-5-8-17)16-28-21-10-6-9-18(19)22(21)26/h6,9-10,15,17,20H,2-5,7-8,11-14,16H2,1H3/t20-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 31.6 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416461
(CHEMBL1209502)Show SMILES CCN1CCN(CC1)C(=O)c1cn2C(COc3cccc1c23)C1CCCCC1 Show InChI InChI=1S/C23H31N3O2/c1-2-24-11-13-25(14-12-24)23(27)19-15-26-20(17-7-4-3-5-8-17)16-28-21-10-6-9-18(19)22(21)26/h6,9-10,15,17,20H,2-5,7-8,11-14,16H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 31.6 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50416462
(CHEMBL1209572)Show SMILES CCN1CCN(CC1)C(=O)c1cn2C(CCc3cccc1c23)C1CCCCC1 Show InChI InChI=1S/C24H33N3O/c1-2-25-13-15-26(16-14-25)24(28)21-17-27-22(18-7-4-3-5-8-18)12-11-19-9-6-10-20(21)23(19)27/h6,9-10,17-18,22H,2-5,7-8,11-16H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 25.1 | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells after 5 hrs by luciferase reporter gene assay |
Bioorg Med Chem Lett 20: 4918-21 (2010)
Article DOI: 10.1016/j.bmcl.2010.06.067
BindingDB Entry DOI: 10.7270/Q21R6RS6 |
More data for this
Ligand-Target Pair | |
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