Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50041891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417934 (CHEMBL1668590 | US8829009, 1.1(7)) Show SMILES CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H15ClN4O2S/c1-9-7-10(2)20-15(18-9)13(14(17-3)19-20)23(21,22)12-6-4-5-11(16)8-12/h4-8H,1-3H3,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417915 (CHEMBL1668586 | US8618114, 1.2.3(1)) Show SMILES CNc1nn2c(C)ccnc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H14N4O2S/c1-10-8-9-16-14-12(13(15-2)17-18(10)14)21(19,20)11-6-4-3-5-7-11/h3-9H,1-2H3,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50340725 (CHEMBL1668584 | N,5,7-trimethyl-3-(phenylsulfonyl)...) Show SMILES CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H16N4O2S/c1-10-9-11(2)19-15(17-10)13(14(16-3)18-19)22(20,21)12-7-5-4-6-8-12/h4-9H,1-3H3,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417916 (CHEMBL1668564 | US8618114, 1.2.5(1)) Show SMILES CNc1nn2c(C)cc(COC)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C16H18N4O3S/c1-11-9-12(10-23-3)18-16-14(15(17-2)19-20(11)16)24(21,22)13-7-5-4-6-8-13/h4-9H,10H2,1-3H3,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.269	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417917 (CHEMBL1668565 | US8618114, 1.2.6(1)) Show SMILES CNc1nn2c(CO)cc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H16N4O3S/c1-10-8-11(9-20)19-15(17-10)13(14(16-2)18-19)23(21,22)12-6-4-3-5-7-12/h3-8,20H,9H2,1-2H3,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417920 (CHEMBL1668592 | US8829009, 1.1(3)) Show SMILES CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C15H15FN4O2S/c1-9-8-10(2)20-15(18-9)13(14(17-3)19-20)23(21,22)12-6-4-11(16)5-7-12/h4-8H,1-3H3,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417933 (CHEMBL1668588 | US8618114, 1.2.7(1)) Show SMILES CNc1nn2c(C)cc(CO)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H16N4O3S/c1-10-8-11(9-20)17-15-13(14(16-2)18-19(10)15)23(21,22)12-6-4-3-5-7-12/h3-8,20H,9H2,1-2H3,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417919 (CHEMBL1668591 | US8829009, 1.1(5)) Show SMILES CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C15H15FN4O2S/c1-9-7-10(2)20-15(18-9)13(14(17-3)19-20)23(21,22)12-6-4-5-11(16)8-12/h4-8H,1-3H3,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417904 (CHEMBL1668568 | US8618114, 1.1.6(1)) Show SMILES CSc1nn2c(CO)cc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H15N3O3S2/c1-10-8-11(9-19)18-14(16-10)13(15(17-18)22-2)23(20,21)12-6-4-3-5-7-12/h3-8,19H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417936 (CHEMBL1668596 | US8829009, 1.1(9)) Show SMILES CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C15H14ClFN4O2S/c1-8-6-9(2)21-15(19-8)13(14(18-3)20-21)24(22,23)10-4-5-12(17)11(16)7-10/h4-7H,1-3H3,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.603	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417906 (CHEMBL1668571 | US8552005, 1.1(11)) Show SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H14ClN3O2S2/c1-9-7-10(2)19-14(17-9)13(15(18-19)22-3)23(20,21)12-6-4-5-11(16)8-12/h4-8H,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.759	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417907 (CHEMBL1668572 | US8552005, 1.1(9)) Show SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C15H14FN3O2S2/c1-9-7-10(2)19-14(17-9)13(15(18-19)22-3)23(20,21)12-6-4-5-11(16)8-12/h4-8H,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417918 (CHEMBL1668589 | US8618114, 1.2.1(4)) Show SMILES CNc1nn2cccnc2c1S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C13H11ClN4O2S/c1-15-12-11(13-16-6-3-7-18(13)17-12)21(19,20)10-5-2-4-9(14)8-10/h2-8H,1H3,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50340726 (5,7-dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyra...) Show SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H15N3O2S2/c1-10-9-11(2)18-14(16-10)13(15(17-18)21-3)22(19,20)12-7-5-4-6-8-12/h4-9H,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417914 (CHEMBL1668585 | US8618114, 1.2.2(1)) Show SMILES CNc1nn2ccc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H14N4O2S/c1-10-8-9-18-14(16-10)12(13(15-2)17-18)21(19,20)11-6-4-3-5-7-11/h3-9H,1-2H3,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417937 (CHEMBL1668594) Show SMILES CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(O)cc1 Show InChI InChI=1S/C15H16N4O3S/c1-9-8-10(2)19-15(17-9)13(14(16-3)18-19)23(21,22)12-6-4-11(20)5-7-12/h4-8,20H,1-3H3,(H,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417905 (CHEMBL1668569 | US8618114, 1.1.7(1)) Show SMILES CSc1nn2c(C)cc(CO)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H15N3O3S2/c1-10-8-11(9-19)16-14-13(15(22-2)17-18(10)14)23(20,21)12-6-4-3-5-7-12/h3-8,19H,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417928 (CHEMBL1668573 | US8552005, 1.1(16)) Show SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C15H14ClN3O2S2/c1-9-8-10(2)19-14(17-9)13(15(18-19)22-3)23(20,21)12-6-4-11(16)5-7-12/h4-8H,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417926 (CHEMBL1668567 | US8618114, 1.1.5(1)) Show SMILES COCc1cc(C)n2nc(SC)c(c2n1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C16H17N3O3S2/c1-11-9-12(10-22-2)17-15-14(16(23-3)18-19(11)15)24(20,21)13-7-5-4-6-8-13/h4-9H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417912 (CHEMBL1668580 | US8552005, 1.1(20)) Show SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C15H13ClFN3O2S2/c1-8-6-9(2)20-14(18-8)13(15(19-20)23-3)24(21,22)10-4-5-12(17)11(16)7-10/h4-7H,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417913 (CHEMBL1668583 | US8618114, 1.2.1(1)) Show SMILES CNc1nn2cccnc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C13H12N4O2S/c1-14-12-11(13-15-8-5-9-17(13)16-12)20(18,19)10-6-3-2-4-7-10/h2-9H,1H3,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417909 (CHEMBL1668576) Show SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(O)cc1 Show InChI InChI=1S/C15H15N3O3S2/c1-9-8-10(2)18-14(16-9)13(15(17-18)22-3)23(20,21)12-6-4-11(19)5-7-12/h4-8,19H,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417908 (CHEMBL1668574 | US8552005, 1.1(7)) Show SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C15H14FN3O2S2/c1-9-8-10(2)19-14(17-9)13(15(18-19)22-3)23(20,21)12-6-4-11(16)5-7-12/h4-8H,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417932 (CHEMBL1668587 | US8618114, 1.2.4(1)) Show SMILES CNc1nn2c(COC)cc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C16H18N4O3S/c1-11-9-12(10-23-3)20-16(18-11)14(15(17-2)19-20)24(21,22)13-7-5-4-6-8-13/h4-9H,10H2,1-3H3,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417931 (CHEMBL1668581 | US8618114, 1.1.2(5)) Show SMILES CSc1nn2ccc(C)nc2c1S(=O)(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H11ClFN3O2S2/c1-8-5-6-19-13(17-8)12(14(18-19)22-2)23(20,21)9-3-4-11(16)10(15)7-9/h3-7H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417921 (CHEMBL1668595) Show SMILES CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(OC)cc1 Show InChI InChI=1S/C16H18N4O3S/c1-10-9-11(2)20-16(18-10)14(15(17-3)19-20)24(21,22)13-7-5-12(23-4)6-8-13/h5-9H,1-4H3,(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417935 (CHEMBL1668593 | US8618114, 1.2.1(2)) Show SMILES CNc1nn2cccnc2c1S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C13H11FN4O2S/c1-15-12-11(13-16-7-2-8-18(13)17-12)21(19,20)10-5-3-9(14)4-6-10/h2-8H,1H3,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417927 (CHEMBL1668570 | US8618114, 1.1.1(3)) Show SMILES CSc1nn2cccnc2c1S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C13H10ClN3O2S2/c1-20-13-11(12-15-6-3-7-17(12)16-13)21(18,19)10-5-2-4-9(14)8-10/h2-8H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417923 (CHEMBL1668501 | US8618114, 1.1.2(1)) Show SMILES CSc1nn2ccc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H13N3O2S2/c1-10-8-9-17-13(15-10)12(14(16-17)20-2)21(18,19)11-6-4-3-5-7-11/h3-9H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417924 (CHEMBL1668502 | US8618114, 1.1.3(1)) Show SMILES CSc1nn2c(C)ccnc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H13N3O2S2/c1-10-8-9-15-13-12(14(20-2)16-17(10)13)21(18,19)11-6-4-3-5-7-11/h3-9H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417910 (CHEMBL1668577 | US8552005, 1.1(17)) Show SMILES COc1ccc(cc1)S(=O)(=O)c1c(SC)nn2c(C)cc(C)nc12 Show InChI InChI=1S/C16H17N3O3S2/c1-10-9-11(2)19-15(17-10)14(16(18-19)23-4)24(20,21)13-7-5-12(22-3)6-8-13/h5-9H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417930 (CHEMBL1668578) Show SMILES CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(cc1)N(C)C Show InChI InChI=1S/C17H20N4O2S2/c1-11-10-12(2)21-16(18-11)15(17(19-21)24-5)25(22,23)14-8-6-13(7-9-14)20(3)4/h6-10H,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417911 (CHEMBL1668579 | US8618114, 1.1.1(4)) Show SMILES CSc1nn2cccnc2c1S(=O)(=O)c1ccc(F)c(Cl)c1 Show InChI InChI=1S/C13H9ClFN3O2S2/c1-21-13-11(12-16-5-2-6-18(12)17-13)22(19,20)8-3-4-10(15)9(14)7-8/h2-7H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417922 (CHEMBL1668499 | US8618114, 1.1.1(1)) Show SMILES CSc1nn2cccnc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C13H11N3O2S2/c1-19-13-11(12-14-8-5-9-16(12)15-13)20(17,18)10-6-3-2-4-7-10/h2-9H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417929 (CHEMBL1668575 | US8618114, 1.1.1(7)) Show SMILES CSc1nn2cccnc2c1S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C13H10FN3O2S2/c1-20-13-11(12-15-7-2-8-17(12)16-13)21(18,19)10-5-3-9(14)4-6-10/h2-8H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417925 (CHEMBL1668566) Show SMILES COCc1cc(C)nc2c(c(SC)nn12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C16H17N3O3S2/c1-11-9-12(10-22-2)19-15(17-11)14(16(18-19)23-3)24(20,21)13-7-5-4-6-8-13/h4-9H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair