Compile Data Set for Download or QSAR

Found 178 hits Enz. Inhib. hit(s) with all data for entry = 969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301008 (4-[5-(4-methylphenyl)-1-[[(3R)- pyrrolidin-3-yl]me...) Show SMILES Cc1ccc(cc1)-c1nc2ccn(C[C@@H]3CCNC3)c2cc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H24N4/c1-18-2-6-22(7-3-18)26-23(21-8-4-19(15-27)5-9-21)14-25-24(29-26)11-13-30(25)17-20-10-12-28-16-20/h2-9,11,13-14,20,28H,10,12,16-17H2,1H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301010 (4-[5-(4-methylphenyl)-1-[[(3S)- pyrrolidin-3-yl]me...) Show SMILES Cc1ccc(cc1)-c1nc2ccn(C[C@H]3CCNC3)c2cc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H24N4/c1-18-2-6-22(7-3-18)26-23(21-8-4-19(15-27)5-9-21)14-25-24(29-26)11-13-30(25)17-20-10-12-28-16-20/h2-9,11,13-14,20,28H,10,12,16-17H2,1H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301012 (4-[5-(4-fluorophenyl)-1-[[(3S)- pyrrolidin-3-yl]me...) Show SMILES Fc1ccc(cc1)-c1nc2ccn(C[C@H]3CCNC3)c2cc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C25H21FN4/c26-21-7-5-20(6-8-21)25-22(19-3-1-17(14-27)2-4-19)13-24-23(29-25)10-12-30(24)16-18-9-11-28-15-18/h1-8,10,12-13,18,28H,9,11,15-16H2/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301014 (4-[5-morpholin-4-yl-1-[[(3S)- pyrrolidin-3-yl]meth...) Show SMILES N#Cc1ccc(cc1)-c1cc2n(C[C@H]3CCNC3)ccc2nc1N1CCOCC1 |r| Show InChI InChI=1S/C23H25N5O/c24-14-17-1-3-19(4-2-17)20-13-22-21(26-23(20)27-9-11-29-12-10-27)6-8-28(22)16-18-5-7-25-15-18/h1-4,6,8,13,18,25H,5,7,9-12,15-16H2/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301016 (4-[1-[(3-fluoropyrrolidin-3-yl)methyl]- 5-(4-methy...) Show SMILES Cc1ccc(cc1)-c1nc2ccn(CC3(F)CCNC3)c2cc1-c1ccc(cc1)C#N Show InChI InChI=1S/C26H23FN4/c1-18-2-6-21(7-3-18)25-22(20-8-4-19(15-28)5-9-20)14-24-23(30-25)10-13-31(24)17-26(27)11-12-29-16-26/h2-10,13-14,29H,11-12,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301017 (4-[5-(4-methylphenyl)-1-[[(2R)- morpholin-2-yl]met...) Show SMILES Cc1ccc(cc1)-c1nc2ccn(C[C@H]3CNCCO3)c2cc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H24N4O/c1-18-2-6-21(7-3-18)26-23(20-8-4-19(15-27)5-9-20)14-25-24(29-26)10-12-30(25)17-22-16-28-11-13-31-22/h2-10,12,14,22,28H,11,13,16-17H2,1H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301018 (4-[5-(4-fluorophenyl)-1-[[(2R)- morpholin-2-yl]met...) Show SMILES Fc1ccc(cc1)-c1nc2ccn(C[C@H]3CNCCO3)c2cc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C25H21FN4O/c26-20-7-5-19(6-8-20)25-22(18-3-1-17(14-27)2-4-18)13-24-23(29-25)9-11-30(24)16-21-15-28-10-12-31-21/h1-9,11,13,21,28H,10,12,15-16H2/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301019 (4-[1-(3-aminopropyl)-5-(4- methylphenyl)pyrrolo[3,...) Show SMILES Cc1ccc(cc1)-c1nc2ccn(CCCN)c2cc1-c1ccc(cc1)C#N Show InChI InChI=1S/C24H22N4/c1-17-3-7-20(8-4-17)24-21(19-9-5-18(16-26)6-10-19)15-23-22(27-24)11-14-28(23)13-2-12-25/h3-11,14-15H,2,12-13,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301020 (4-[5-(4-methylphenyl)-1-(pyrrolidin-3- ylmethyl)py...) Show SMILES Cc1ccc(cc1)-c1nc2cnn(CC3CCNC3)c2cc1-c1ccc(cc1)C#N Show InChI InChI=1S/C25H23N5/c1-17-2-6-21(7-3-17)25-22(20-8-4-18(13-26)5-9-20)12-24-23(29-25)15-28-30(24)16-19-10-11-27-14-19/h2-9,12,15,19,27H,10-11,14,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301021 (4-[5-(4-methylphenyl)-1-(piperidin-4- ylmethyl)pyr...) Show SMILES Cc1ccc(cc1)-c1nc2cnn(CC3CCNCC3)c2cc1-c1ccc(cc1)C#N Show InChI InChI=1S/C26H25N5/c1-18-2-6-22(7-3-18)26-23(21-8-4-19(15-27)5-9-21)14-25-24(30-26)16-29-31(25)17-20-10-12-28-13-11-20/h2-9,14,16,20,28H,10-13,17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301022 (4-[1-[[(1S,5R)-3- azabicyclo[3.1.0]hexan-6-yl]meth...) Show SMILES Cc1ccc(cc1)-c1nc2cnn(C[C@H]3[C@@H]4CNC[C@H]34)c2cc1-c1ccc(cc1)[N+]#[C-] |r| Show InChI InChI=1S/C26H23N5/c1-16-3-5-18(6-4-16)26-20(17-7-9-19(27-2)10-8-17)11-25-24(30-26)14-29-31(25)15-23-21-12-28-13-22(21)23/h3-11,14,21-23,28H,12-13,15H2,1H3/t21-,22+,23+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50158880 (CHEMBL3785783 | US10131664, Example 16 | US1054319...) Show SMILES Cc1ccc(cc1)-c1cnc(NC[C@H]2CCNC2)nc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C23H23N5/c1-16-2-6-19(7-3-16)21-15-27-23(26-14-18-10-11-25-13-18)28-22(21)20-8-4-17(12-24)5-9-20/h2-9,15,18,25H,10-11,13-14H2,1H3,(H,26,27,28)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301025 (4-[5-(4-fluorophenyl)-2-{[(3S)- pyrrolidin-3- ylme...) Show SMILES Fc1ccc(cc1)-c1cnc(NC[C@H]2CCNC2)nc1-c1ccc(cc1)C#N |r,$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C22H20FN5/c23-19-7-5-17(6-8-19)20-14-27-22(26-13-16-9-10-25-12-16)28-21(20)18-3-1-15(11-24)2-4-18/h1-8,14,16,25H,9-10,12-13H2,(H,26,27,28)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301026 (4-[5-(4-chlorophenyl)-2-{[(3S)- pyrrolidin-3- ylme...) Show SMILES Clc1ccc(cc1)-c1cnc(NC[C@H]2CCNC2)nc1-c1ccc(cc1)C#N |r,$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C22H20ClN5/c23-19-7-5-17(6-8-19)20-14-27-22(26-13-16-9-10-25-12-16)28-21(20)18-3-1-15(11-24)2-4-18/h1-8,14,16,25H,9-10,12-13H2,(H,26,27,28)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301027 (4-[5-(4-methylphenyl)-2-[(3R)- pyrrolidin-3-ylmeth...) Show SMILES Cc1ccc(cc1)-c1cnc(OC[C@@H]2CCNC2)nc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C23H22N4O/c1-16-2-6-19(7-3-16)21-14-26-23(28-15-18-10-11-25-13-18)27-22(21)20-8-4-17(12-24)5-9-20/h2-9,14,18,25H,10-11,13,15H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301028 (4-{2-[(3aR,6aS)-octahydropyrrolo[3,4- c]pyrrol-2-y...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1C[C@@H]2CNC[C@@H]2C1 |r| Show InChI InChI=1S/C24H23N5/c1-16-2-6-18(7-3-16)22-13-27-24(29-14-20-11-26-12-21(20)15-29)28-23(22)19-8-4-17(10-25)5-9-19/h2-9,13,20-21,26H,11-12,14-15H2,1H3/t20-,21+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301029 (4-[5-(4-methylphenyl)-2-{octahydro- 1H-pyrrolo[3,4...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC2CNCC2C1 Show InChI InChI=1S/C25H25N5/c1-17-2-6-19(7-3-17)23-15-28-25(30-11-10-21-13-27-14-22(21)16-30)29-24(23)20-8-4-18(12-26)5-9-20/h2-9,15,21-22,27H,10-11,13-14,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301030 (4-{2-[(3aR,8aS)-decahydropyrrolo[3,4- d]azepin-6-y...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CC[C@@H]2CNC[C@@H]2CC1 |r| Show InChI InChI=1S/C26H27N5/c1-18-2-6-20(7-3-18)24-17-29-26(30-25(24)21-8-4-19(14-27)5-9-21)31-12-10-22-15-28-16-23(22)11-13-31/h2-9,17,22-23,28H,10-13,15-16H2,1H3/t22-,23+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301031 (4-{2-[(3aR,8aS)-decahydropyrrolo[3,4- d]azepin-6-y...) Show SMILES Fc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CC[C@@H]2CNC[C@@H]2CC1 |r| Show InChI InChI=1S/C25H24FN5/c26-22-7-5-18(6-8-22)23-16-29-25(30-24(23)19-3-1-17(13-27)2-4-19)31-11-9-20-14-28-15-21(20)10-12-31/h1-8,16,20-21,28H,9-12,14-15H2/t20-,21+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301032 (4-(2-{[(3S)-pyrrolidin-3- ylmethyl]amino}-5-[4- (t...) Show SMILES FC(F)(F)c1ccc(cc1)-c1cnc(NC[C@H]2CCNC2)nc1-c1ccc(cc1)C#N |r,$;;;;;;;;;;;;;;HN;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H20F3N5/c24-23(25,26)19-7-5-17(6-8-19)20-14-30-22(29-13-16-9-10-28-12-16)31-21(20)18-3-1-15(11-27)2-4-18/h1-8,14,16,28H,9-10,12-13H2,(H,29,30,31)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301033 (4-[5-(2-cyclopropylethynyl)-2-{[(3S)- pyrrolidin-3...) Show SMILES N#Cc1ccc(cc1)-c1nc(NC[C@H]2CCNC2)ncc1C#CC1CC1 |r,$;;;;;;;;;;;HN;;;;;;;;;;;;;;$| Show InChI InChI=1S/C21H21N5/c22-11-16-4-6-18(7-5-16)20-19(8-3-15-1-2-15)14-25-21(26-20)24-13-17-9-10-23-12-17/h4-7,14-15,17,23H,1-2,9-10,12-13H2,(H,24,25,26)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301035 ((+-)-4-(2-{[(3-fluoropyrrolidin-3- yl)methyl]amino...) Show SMILES Cc1ccc(cc1)-c1cnc(NCC2(F)CCNC2)nc1-c1ccc(cc1)C#N |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H22FN5/c1-16-2-6-18(7-3-16)20-13-27-22(28-15-23(24)10-11-26-14-23)29-21(20)19-8-4-17(12-25)5-9-19/h2-9,13,26H,10-11,14-15H2,1H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301036 ((+-)-4-[5-(4-methylphenyl)-2- [(piperidin-3-yl)ami...) Show SMILES Cc1ccc(cc1)-c1cnc(NC2CCCNC2)nc1-c1ccc(cc1)C#N |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H23N5/c1-16-4-8-18(9-5-16)21-15-26-23(27-20-3-2-12-25-14-20)28-22(21)19-10-6-17(13-24)7-11-19/h4-11,15,20,25H,2-3,12,14H2,1H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301037 (4-[5-(4-methylphenyl)-2-[(piperidin-4- yl)amino]py...) Show SMILES Cc1ccc(cc1)-c1cnc(NC2CCNCC2)nc1-c1ccc(cc1)C#N |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H23N5/c1-16-2-6-18(7-3-16)21-15-26-23(27-20-10-12-25-13-11-20)28-22(21)19-8-4-17(14-24)5-9-19/h2-9,15,20,25H,10-13H2,1H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301038 ((+-)-4-[5-(4-methylphenyl)-2- [(piperidin-3- ylmet...) Show SMILES Cc1ccc(cc1)-c1cnc(NCC2CCCNC2)nc1-c1ccc(cc1)C#N |$;;;;;;;;;;;HN;;;;;;HN;;;;;;;;;;;$| Show InChI InChI=1S/C24H25N5/c1-17-4-8-20(9-5-17)22-16-28-24(27-15-19-3-2-12-26-14-19)29-23(22)21-10-6-18(13-25)7-11-21/h4-11,16,19,26H,2-3,12,14-15H2,1H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301039 (4-[5-(4-methylphenyl)-2-[(piperidin-4- ylmethyl)am...) Show SMILES Cc1ccc(cc1)-c1cnc(NCC2CCNCC2)nc1-c1ccc(cc1)C#N |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C24H25N5/c1-17-2-6-20(7-3-17)22-16-28-24(27-15-19-10-12-26-13-11-19)29-23(22)21-8-4-18(14-25)5-9-21/h2-9,16,19,26H,10-13,15H2,1H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301040 ((+-)-4-[5-(4-methylphenyl)-2- [(morpholin-2- ylmet...) Show SMILES Cc1ccc(cc1)-c1cnc(NCC2CNCCO2)nc1-c1ccc(cc1)C#N |$;;;;;;;;;;;HN;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C23H23N5O/c1-16-2-6-18(7-3-16)21-15-27-23(26-14-20-13-25-10-11-29-20)28-22(21)19-8-4-17(12-24)5-9-19/h2-9,15,20,25H,10-11,13-14H2,1H3,(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301042 (4-(2-{2,7-diazaspiro[4.4]nonan-2-yl}- 5-(4-methylp...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC2(CCNC2)C1 Show InChI InChI=1S/C25H25N5/c1-18-2-6-20(7-3-18)22-15-28-24(30-13-11-25(17-30)10-12-27-16-25)29-23(22)21-8-4-19(14-26)5-9-21/h2-9,15,27H,10-13,16-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301043 (4-(2-{2,8-diazaspiro[4.5]decan-2-yl}- 5-(4-methylp...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC2(C1)CCNCC2 Show InChI InChI=1S/C26H27N5/c1-19-2-6-21(7-3-19)23-17-29-25(30-24(23)22-8-4-20(16-27)5-9-22)31-15-12-26(18-31)10-13-28-14-11-26/h2-9,17,28H,10-15,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301044 (4-[5-(4-methylphenyl)-2-{octahydro- 1H-pyrrolo[3,4...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CC2CCNCC2C1 Show InChI InChI=1S/C25H25N5/c1-17-2-6-19(7-3-17)23-14-28-25(30-15-21-10-11-27-13-22(21)16-30)29-24(23)20-8-4-18(12-26)5-9-20/h2-9,14,21-22,27H,10-11,13,15-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301045 (4-[5-(4-methylphenyl)-2-{octahydro- 1H-pyrrolo[3,2...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC2NCCC2C1 |$;;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;$| Show InChI InChI=1S/C25H25N5/c1-17-2-6-19(7-3-17)22-15-28-25(30-13-11-23-21(16-30)10-12-27-23)29-24(22)20-8-4-18(14-26)5-9-20/h2-9,15,21,23,27H,10-13,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301046 (4-(2-{2,8-diazaspiro[4.5]decan-8-yl}- 5-(4-methylp...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC2(CCNC2)CC1 Show InChI InChI=1S/C26H27N5/c1-19-2-6-21(7-3-19)23-17-29-25(30-24(23)22-8-4-20(16-27)5-9-22)31-14-11-26(12-15-31)10-13-28-18-26/h2-9,17,28H,10-15,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301047 (4-(2-{1,8-diazaspiro[4.5]decan-8-yl}- 5-(4-methylp...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC2(CCCN2)CC1 Show InChI InChI=1S/C26H27N5/c1-19-3-7-21(8-4-19)23-18-28-25(30-24(23)22-9-5-20(17-27)6-10-22)31-15-12-26(13-16-31)11-2-14-29-26/h3-10,18,29H,2,11-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301050 (4-[5-(4-methylphenyl)-3-(pyrrolidin-3- ylmethylami...) Show SMILES Cc1ccc(cc1)-c1cc(NCC2CCNC2)nn1-c1ccc(cc1)C#N Show InChI InChI=1S/C22H23N5/c1-16-2-6-19(7-3-16)21-12-22(25-15-18-10-11-24-14-18)26-27(21)20-8-4-17(13-23)5-9-20/h2-9,12,18,24H,10-11,14-15H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301051 (4-[5-(4-methylphenyl)-3-[[(3S)- pyrrolidin-3-yl]me...) Show SMILES Cc1ccc(cc1)-c1cc(NC[C@H]2CCNC2)nn1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H23N5/c1-16-2-6-19(7-3-16)21-12-22(25-15-18-10-11-24-14-18)26-27(21)20-8-4-17(13-23)5-9-20/h2-9,12,18,24H,10-11,14-15H2,1H3,(H,25,26)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301052 (4-[5-(4-methylphenyl)-3-[[(3R)- pyrrolidin-3-yl]me...) Show SMILES Cc1ccc(cc1)-c1cc(NC[C@@H]2CCNC2)nn1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H23N5/c1-16-2-6-19(7-3-16)21-12-22(25-15-18-10-11-24-14-18)26-27(21)20-8-4-17(13-23)5-9-20/h2-9,12,18,24H,10-11,14-15H2,1H3,(H,25,26)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301053 (4-[5-(4-methylphenyl)-3-(piperidin-4- ylmethylamin...) Show SMILES Cc1ccc(cc1)-c1cc(NCC2CCNCC2)nn1-c1ccc(cc1)C#N Show InChI InChI=1S/C23H25N5/c1-17-2-6-20(7-3-17)22-14-23(26-16-19-10-12-25-13-11-19)27-28(22)21-8-4-18(15-24)5-9-21/h2-9,14,19,25H,10-13,16H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301054 (4-[3-[[(1S,5R)-3- azabicyclo[3.1.0]hexan-6- yl]met...) Show SMILES Cc1ccc(cc1)-c1cc(NC[C@H]2[C@@H]3CNC[C@H]23)nn1-c1ccc(cc1)[N+]#[C-] |r| Show InChI InChI=1S/C23H23N5/c1-15-3-5-16(6-4-15)22-11-23(26-14-21-19-12-25-13-20(19)21)27-28(22)18-9-7-17(24-2)8-10-18/h3-11,19-21,25H,12-14H2,1H3,(H,26,27)/t19-,20+,21+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301056 (4-{1-[((3R)pyrrolidin-3-yl)methyl]-5- (4-methoxyph...) Show SMILES COc1ccc(cc1)-c1nc2ccn(C[C@@H]3CCNC3)c2cc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H24N4O/c1-31-22-8-6-21(7-9-22)26-23(20-4-2-18(15-27)3-5-20)14-25-24(29-26)11-13-30(25)17-19-10-12-28-16-19/h2-9,11,13-14,19,28H,10,12,16-17H2,1H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301057 (4-{1-[((3R)pyrrolidin-3-yl)methyl]-5- (3-fluoro-4-...) Show SMILES COc1ccc(cc1F)-c1nc2ccn(C[C@@H]3CCNC3)c2cc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H23FN4O/c1-32-25-7-6-20(12-22(25)27)26-21(19-4-2-17(14-28)3-5-19)13-24-23(30-26)9-11-31(24)16-18-8-10-29-15-18/h2-7,9,11-13,18,29H,8,10,15-16H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301058 (4-{1-[((3S)pyrrolidin-3-yl)methyl]-5- (3-fluoro-4-...) Show SMILES COc1ccc(cc1F)-c1nc2ccn(C[C@H]3CCNC3)c2cc1-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H23FN4O/c1-32-25-7-6-20(12-22(25)27)26-21(19-4-2-17(14-28)3-5-19)13-24-23(30-26)9-11-31(24)16-18-8-10-29-15-18/h2-7,9,11-13,18,29H,8,10,15-16H2,1H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301059 (4-{1-[((3R)pyrrolidin-3-yl)methyl]-5- (4-methoxyph...) Show SMILES COc1ccc(cc1)-c1nc2ccn(C[C@@H]3CCNC3)c2cc1-c1ccc(C#N)c(F)c1 |r| Show InChI InChI=1S/C26H23FN4O/c1-32-21-6-4-18(5-7-21)26-22(19-2-3-20(14-28)23(27)12-19)13-25-24(30-26)9-11-31(25)16-17-8-10-29-15-17/h2-7,9,11-13,17,29H,8,10,15-16H2,1H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301060 (4-{1-[((3R)pyrrolidin-3-yl)methyl]-5- (3-fluoro-4-...) Show SMILES COc1ccc(cc1F)-c1nc2ccn(C[C@@H]3CCNC3)c2cc1-c1ccc(C#N)c(F)c1 |r| Show InChI InChI=1S/C26H22F2N4O/c1-33-25-5-4-18(11-22(25)28)26-20(17-2-3-19(13-29)21(27)10-17)12-24-23(31-26)7-9-32(24)15-16-6-8-30-14-16/h2-5,7,9-12,16,30H,6,8,14-15H2,1H3/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301061 (4-[5-morpholin-4-yl-1-[[(3R)- pyrrolidin-3-yl]meth...) Show SMILES COc1ccc(cc1)-c1nc2ccn(C[C@H]3CCNC3)c2cc1-c1ccc(C#N)c(F)c1 |r| Show InChI InChI=1S/C26H23FN4O/c1-32-21-6-4-18(5-7-21)26-22(19-2-3-20(14-28)23(27)12-19)13-25-24(30-26)9-11-31(25)16-17-8-10-29-15-17/h2-7,9,11-13,17,29H,8,10,15-16H2,1H3/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301062 (4-{1-[((3R)pyrrolidin-3-yl)methyl]-5- (3-fluoro-4-...) Show SMILES COc1ccc(cc1F)-c1nc2ccn(C[C@H]3CCNC3)c2cc1-c1ccc(C#N)c(F)c1 |r| Show InChI InChI=1S/C26H22F2N4O/c1-33-25-5-4-18(11-22(25)28)26-20(17-2-3-19(13-29)21(27)10-17)12-24-23(31-26)7-9-32(24)15-16-6-8-30-14-16/h2-5,7,9-12,16,30H,6,8,14-15H2,1H3/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301063 (4-{3-[((3R)-3- aminopiperidyl)carbonyl]-5-(2- pyri...) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OCc2ccccn2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H22N6O2/c23-13-16-6-8-19(9-7-16)28-21(30-15-18-5-1-2-10-25-18)12-20(26-28)22(29)27-11-3-4-17(24)14-27/h1-2,5-10,12,17H,3-4,11,14-15,24H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301064 (4-{3-[((3R)-3-aminopiperidyl) carbonyl]-5-(3-pyrid...) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OCc2cccnc2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H22N6O2/c23-12-16-5-7-19(8-6-16)28-21(30-15-17-3-1-9-25-13-17)11-20(26-28)22(29)27-10-2-4-18(24)14-27/h1,3,5-9,11,13,18H,2,4,10,14-15,24H2/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301065 (4-{3-[((3R)-3-aminopiperidyl) carbonyl]-5-(4-pyrid...) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OCc2ccncc2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H22N6O2/c23-13-16-3-5-19(6-4-16)28-21(30-15-17-7-9-25-10-8-17)12-20(26-28)22(29)27-11-1-2-18(24)14-27/h3-10,12,18H,1-2,11,14-15,24H2/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301066 (4-[2-(4-aminopiperidin-1-yl)-5-(2- methylindazol-5...) Show SMILES Cn1cc2cc(ccc2n1)-c1cnc(nc1-c1ccc(C#N)c(F)c1)N1CCC(N)CC1 Show InChI InChI=1S/C24H22FN7/c1-31-14-18-10-15(4-5-22(18)30-31)20-13-28-24(32-8-6-19(27)7-9-32)29-23(20)16-2-3-17(12-26)21(25)11-16/h2-5,10-11,13-14,19H,6-9,27H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301067 (4-[2-(1,2,3,3a,4,6,7,7a- octahydropyrrolo[3,2-c]py...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC2NCCC2C1 Show InChI InChI=1S/C25H25N5/c1-17-2-6-19(7-3-17)22-15-28-25(30-13-11-23-21(16-30)10-12-27-23)29-24(22)20-8-4-18(14-26)5-9-20/h2-9,15,21,23,27H,10-13,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...				US Patent US10131664 (2018) BindingDB Entry DOI: 10.7270/Q2JD4ZV1
					More data for this Ligand-Target Pair

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