Compile Data Set for Download or QSAR

Found 159 hits Enz. Inhib. hit(s) with all data for entry = 1002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302404 (US9598416, Example 50) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCN(C)CC2)cn2ncnc(N)c12 Show InChI InChI=1S/C22H26N6OS/c1-14-8-15-10-18(30-21(15)17(9-14)29-3)19-16(11-27-6-4-26(2)5-7-27)12-28-20(19)22(23)24-13-25-28/h8-10,12-13H,4-7,11H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302362 (6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCCN)cn2ncnc(N)c12 Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-15(27-18(12)14(6-11)25-2)16-13(9-26-4-3-20)8-24-17(16)19(21)22-10-23-24/h5-8,10H,3-4,9,20H2,1-2H3,(H2,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302363 (N-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC(C)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C19H19N5O2S/c1-10-4-12-6-15(27-18(12)14(5-10)26-3)16-13(7-21-11(2)25)8-24-17(16)19(20)22-9-23-24/h4-6,8-9H,7H2,1-3H3,(H,21,25)(H2,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302362 (6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCCN)cn2ncnc(N)c12 Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-15(27-18(12)14(6-11)25-2)16-13(9-26-4-3-20)8-24-17(16)19(21)22-10-23-24/h5-8,10H,3-4,9,20H2,1-2H3,(H2,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302404 (US9598416, Example 50) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCN(C)CC2)cn2ncnc(N)c12 Show InChI InChI=1S/C22H26N6OS/c1-14-8-15-10-18(30-21(15)17(9-14)29-3)19-16(11-27-6-4-26(2)5-7-27)12-28-20(19)22(23)24-13-25-28/h8-10,12-13H,4-7,11H2,1-3H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302385 (4-{[4-Amino-5-(5-chloro-7-methoxy-1-benzothiophen-...) Show SMILES COc1cc(Cl)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C20H19ClN6O2S/c1-29-14-6-13(21)4-11-5-15(30-19(11)14)17-12(7-26-3-2-23-16(28)9-26)8-27-18(17)20(22)24-10-25-27/h4-6,8,10H,2-3,7,9H2,1H3,(H,23,28)(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302379 (5-(7-Methoxy-5-methyl-1-benzothiophen-2-yl)-6-(pip...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H24N6OS/c1-13-7-14-9-17(29-20(14)16(8-13)28-2)18-15(10-26-5-3-23-4-6-26)11-27-19(18)21(22)24-12-25-27/h7-9,11-12,23H,3-6,10H2,1-2H3,(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302365 (4-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H22N6O2S/c1-12-5-13-7-16(30-20(13)15(6-12)29-2)18-14(8-26-4-3-23-17(28)10-26)9-27-19(18)21(22)24-11-25-27/h5-7,9,11H,3-4,8,10H2,1-2H3,(H,23,28)(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302420 (US9598416, Example 66) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CC[C@@H](C2)N(C)C)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-19(31-22(15)18(8-14)30-4)20-16(10-28-6-5-17(12-28)27(2)3)11-29-21(20)23(24)25-13-26-29/h7-9,11,13,17H,5-6,10,12H2,1-4H3,(H2,24,25,26)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302381 ((3S)-3-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothi...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN[C@H]2CCNC2=O)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C21H22N6O2S/c1-11-5-12-7-16(30-19(12)15(6-11)29-2)17-13(8-24-14-3-4-23-21(14)28)9-27-18(17)20(22)25-10-26-27/h5-7,9-10,14,24H,3-4,8H2,1-2H3,(H,23,28)(H2,22,25,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302379 (5-(7-Methoxy-5-methyl-1-benzothiophen-2-yl)-6-(pip...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H24N6OS/c1-13-7-14-9-17(29-20(14)16(8-13)28-2)18-15(10-26-5-3-23-4-6-26)11-27-19(18)21(22)24-12-25-27/h7-9,11-12,23H,3-6,10H2,1-2H3,(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302419 (US9598416, Example 65) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CC[C@H](C2)N(C)C)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-19(31-22(15)18(8-14)30-4)20-16(10-28-6-5-17(12-28)27(2)3)11-29-21(20)23(24)25-13-26-29/h7-9,11,13,17H,5-6,10,12H2,1-4H3,(H2,24,25,26)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302421 (US9598416, Example 67) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCC(C2)N(C)C)cn2ncnc(N)c12 Show InChI InChI=1S/C24H30N6OS/c1-15-8-16-10-20(32-23(16)19(9-15)31-4)21-17(12-30-22(21)24(25)26-14-27-30)11-29-7-5-6-18(13-29)28(2)3/h8-10,12,14,18H,5-7,11,13H2,1-4H3,(H2,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302385 (4-{[4-Amino-5-(5-chloro-7-methoxy-1-benzothiophen-...) Show SMILES COc1cc(Cl)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C20H19ClN6O2S/c1-29-14-6-13(21)4-11-5-15(30-19(11)14)17-12(7-26-3-2-23-16(28)9-26)8-27-18(17)20(22)24-10-25-27/h4-6,8,10H,2-3,7,9H2,1H3,(H,23,28)(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302405 (US9598416, Example 51) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C22H25N5OS/c1-14-8-15-10-18(29-21(15)17(9-14)28-2)19-16(11-26-6-4-3-5-7-26)12-27-20(19)22(23)24-13-25-27/h8-10,12-13H,3-7,11H2,1-2H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302419 (US9598416, Example 65) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CC[C@H](C2)N(C)C)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-19(31-22(15)18(8-14)30-4)20-16(10-28-6-5-17(12-28)27(2)3)11-29-21(20)23(24)25-13-26-29/h7-9,11,13,17H,5-6,10,12H2,1-4H3,(H2,24,25,26)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302363 (N-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC(C)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C19H19N5O2S/c1-10-4-12-6-15(27-18(12)14(5-10)26-3)16-13(7-21-11(2)25)8-24-17(16)19(20)22-9-23-24/h4-6,8-9H,7H2,1-3H3,(H,21,25)(H2,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302368 (N2-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN(C)CC(N)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C20H22N6O2S/c1-11-4-12-6-15(29-19(12)14(5-11)28-3)17-13(7-25(2)9-16(21)27)8-26-18(17)20(22)23-10-24-26/h4-6,8,10H,7,9H2,1-3H3,(H2,21,27)(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302422 (US9598416, Example 68) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCN(C)CC2)cn2ncnc(N)c12 Show InChI InChI=1S/C23H28N6OS/c1-15-9-16-11-19(31-22(16)18(10-15)30-3)20-17(12-28-6-4-5-27(2)7-8-28)13-29-21(20)23(24)25-14-26-29/h9-11,13-14H,4-8,12H2,1-3H3,(H2,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302381 ((3S)-3-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothi...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN[C@H]2CCNC2=O)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C21H22N6O2S/c1-11-5-12-7-16(30-19(12)15(6-11)29-2)17-13(8-24-14-3-4-23-21(14)28)9-27-18(17)20(22)25-10-26-27/h5-7,9-10,14,24H,3-4,8H2,1-2H3,(H,23,28)(H2,22,25,26)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302421 (US9598416, Example 67) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCC(C2)N(C)C)cn2ncnc(N)c12 Show InChI InChI=1S/C24H30N6OS/c1-15-8-16-10-20(32-23(16)19(9-15)31-4)21-17(12-30-22(21)24(25)26-14-27-30)11-29-7-5-6-18(13-29)28(2)3/h8-10,12,14,18H,5-7,11,13H2,1-4H3,(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302420 (US9598416, Example 66) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CC[C@@H](C2)N(C)C)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C23H28N6OS/c1-14-7-15-9-19(31-22(15)18(8-14)30-4)20-16(10-28-6-5-17(12-28)27(2)3)11-29-21(20)23(24)25-13-26-29/h7-9,11,13,17H,5-6,10,12H2,1-4H3,(H2,24,25,26)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302401 (US9598416, Example 47) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H23N5OS/c1-13-7-14-9-17(28-20(14)16(8-13)27-2)18-15(10-25-5-3-4-6-25)11-26-19(18)21(22)23-12-24-26/h7-9,11-12H,3-6,10H2,1-2H3,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302364 (2-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCCO)cn2ncnc(N)c12 Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-15(27-18(12)14(6-11)26-2)16-13(8-21-3-4-25)9-24-17(16)19(20)22-10-23-24/h5-7,9-10,21,25H,3-4,8H2,1-2H3,(H2,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302418 (US9598416, Example 64) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCC(CC2)C(N)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C23H26N6O2S/c1-13-7-15-9-18(32-21(15)17(8-13)31-2)19-16(11-29-20(19)22(24)26-12-27-29)10-28-5-3-14(4-6-28)23(25)30/h7-9,11-12,14H,3-6,10H2,1-2H3,(H2,25,30)(H2,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302365 (4-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H22N6O2S/c1-12-5-13-7-16(30-20(13)15(6-12)29-2)18-14(8-26-4-3-23-17(28)10-26)9-27-19(18)21(22)24-11-25-27/h5-7,9,11H,3-4,8,10H2,1-2H3,(H,23,28)(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302400 (US9598416, Example 46) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN(C)CCC#N)cn2ncnc(N)c12 Show InChI InChI=1S/C21H22N6OS/c1-13-7-14-9-17(29-20(14)16(8-13)28-3)18-15(10-26(2)6-4-5-22)11-27-19(18)21(23)24-12-25-27/h7-9,11-12H,4,6,10H2,1-3H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302356 ((2S)-1-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothio...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COC[C@H](C)O)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C20H22N4O3S/c1-11-4-13-6-16(28-19(13)15(5-11)26-3)17-14(9-27-8-12(2)25)7-24-18(17)20(21)22-10-23-24/h4-7,10,12,25H,8-9H2,1-3H3,(H2,21,22,23)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302372 (US9598416, Example 18 | rac-1-{[4-Amino-5-(7-metho...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCC(O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H23N5O2S/c1-12-5-13-7-17(29-20(13)16(6-12)28-2)18-14(8-25-4-3-15(27)10-25)9-26-19(18)21(22)23-11-24-26/h5-7,9,11,15,27H,3-4,8,10H2,1-2H3,(H2,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302409 (US9598416, Example 55) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2C)cn2ncnc(N)c12 Show InChI InChI=1S/C22H24N6O2S/c1-12-6-14-8-17(31-20(14)16(7-12)30-3)18-15(9-27-5-4-24-22(29)13(27)2)10-28-19(18)21(23)25-11-26-28/h6-8,10-11,13H,4-5,9H2,1-3H3,(H,24,29)(H2,23,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302364 (2-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCCO)cn2ncnc(N)c12 Show InChI InChI=1S/C19H21N5O2S/c1-11-5-12-7-15(27-18(12)14(6-11)26-2)16-13(8-21-3-4-25)9-24-17(16)19(20)22-10-23-24/h5-7,9-10,21,25H,3-4,8H2,1-2H3,(H2,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302405 (US9598416, Example 51) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C22H25N5OS/c1-14-8-15-10-18(29-21(15)17(9-14)28-2)19-16(11-26-6-4-3-5-7-26)12-27-20(19)22(23)24-13-25-27/h8-10,12-13H,3-7,11H2,1-2H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302422 (US9598416, Example 68) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCN(C)CC2)cn2ncnc(N)c12 Show InChI InChI=1S/C23H28N6OS/c1-15-9-16-11-19(31-22(16)18(10-15)30-3)20-17(12-28-6-4-5-27(2)7-8-28)13-29-21(20)23(24)25-14-26-29/h9-11,13-14H,4-8,12H2,1-3H3,(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302418 (US9598416, Example 64) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCC(CC2)C(N)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C23H26N6O2S/c1-13-7-15-9-18(32-21(15)17(8-13)31-2)19-16(11-29-20(19)22(24)26-12-27-29)10-28-5-3-14(4-6-28)23(25)30/h7-9,11-12,14H,3-6,10H2,1-2H3,(H2,25,30)(H2,24,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302372 (US9598416, Example 18 | rac-1-{[4-Amino-5-(7-metho...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCC(O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H23N5O2S/c1-12-5-13-7-17(29-20(13)16(6-12)28-2)18-14(8-25-4-3-15(27)10-25)9-26-19(18)21(22)23-11-24-26/h5-7,9,11,15,27H,3-4,8,10H2,1-2H3,(H2,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302401 (US9598416, Example 47) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H23N5OS/c1-13-7-14-9-17(28-20(14)16(8-13)27-2)18-15(10-25-5-3-4-6-25)11-26-19(18)21(22)23-12-24-26/h7-9,11-12H,3-6,10H2,1-2H3,(H2,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302387 (4-{[4-Amino-5-(5,7-dimethoxy-1-benzothiophen-2-yl)...) Show SMILES COc1cc(OC)c2sc(cc2c1)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H22N6O3S/c1-29-14-5-12-6-16(31-20(12)15(7-14)30-2)18-13(8-26-4-3-23-17(28)10-26)9-27-19(18)21(22)24-11-25-27/h5-7,9,11H,3-4,8,10H2,1-2H3,(H,23,28)(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302371 (1-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCC(C)(C)O)cn2ncnc(N)c12 Show InChI InChI=1S/C21H25N5O2S/c1-12-5-13-7-16(29-19(13)15(6-12)28-4)17-14(8-23-10-21(2,3)27)9-26-18(17)20(22)24-11-25-26/h5-7,9,11,23,27H,8,10H2,1-4H3,(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302357 ((2S)-2-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothio...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CO[C@@H](C)CO)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C20H22N4O3S/c1-11-4-13-6-16(28-19(13)15(5-11)26-3)17-14(9-27-12(2)8-25)7-24-18(17)20(21)22-10-23-24/h4-7,10,12,25H,8-9H2,1-3H3,(H2,21,22,23)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302371 (1-({[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCC(C)(C)O)cn2ncnc(N)c12 Show InChI InChI=1S/C21H25N5O2S/c1-12-5-13-7-16(29-19(13)15(6-12)28-4)17-14(8-23-10-21(2,3)27)9-26-18(17)20(22)24-11-25-26/h5-7,9,11,23,27H,8,10H2,1-4H3,(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302380 (US9598416, Example 26 | rac-1-({[4-Amino-5-(7-meth...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCC(C)O)cn2ncnc(N)c12 Show InChI InChI=1S/C20H23N5O2S/c1-11-4-13-6-16(28-19(13)15(5-11)27-3)17-14(8-22-7-12(2)26)9-25-18(17)20(21)23-10-24-25/h4-6,9-10,12,22,26H,7-8H2,1-3H3,(H2,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302380 (US9598416, Example 26 | rac-1-({[4-Amino-5-(7-meth...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCC(C)O)cn2ncnc(N)c12 Show InChI InChI=1S/C20H23N5O2S/c1-11-4-13-6-16(28-19(13)15(5-11)27-3)17-14(8-22-7-12(2)26)9-25-18(17)20(21)23-10-24-25/h4-6,9-10,12,22,26H,7-8H2,1-3H3,(H2,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302356 ((2S)-1-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothio...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COC[C@H](C)O)cn2ncnc(N)c12 |r| Show InChI InChI=1S/C20H22N4O3S/c1-11-4-13-6-16(28-19(13)15(5-11)26-3)17-14(9-27-8-12(2)25)7-24-18(17)20(21)22-10-23-24/h4-7,10,12,25H,8-9H2,1-3H3,(H2,21,22,23)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302368 (N2-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN(C)CC(N)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C20H22N6O2S/c1-11-4-12-6-15(29-19(12)14(5-11)28-3)17-13(7-25(2)9-16(21)27)8-26-18(17)20(22)23-10-24-26/h4-6,8,10H,7,9H2,1-3H3,(H2,21,27)(H2,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302370 (N2-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen...) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCC(N)=O)cn2ncnc(N)c12 Show InChI InChI=1S/C19H20N6O2S/c1-10-3-11-5-14(28-18(11)13(4-10)27-2)16-12(6-22-7-15(20)26)8-25-17(16)19(21)23-9-24-25/h3-5,8-9,22H,6-7H2,1-2H3,(H2,20,26)(H2,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302427 (US9598416, Example 73) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC2CCOC2)cn2ncnc(N)c12 Show InChI InChI=1S/C21H23N5O2S/c1-12-5-13-7-17(29-20(13)16(6-12)27-2)18-14(8-23-15-3-4-28-10-15)9-26-19(18)21(22)24-11-25-26/h5-7,9,11,15,23H,3-4,8,10H2,1-2H3,(H2,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302408 (US9598416, Example 54) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCCOCC2)cn2ncnc(N)c12 Show InChI InChI=1S/C22H25N5O2S/c1-14-8-15-10-18(30-21(15)17(9-14)28-2)19-16(11-26-4-3-6-29-7-5-26)12-27-20(19)22(23)24-13-25-27/h8-10,12-13H,3-7,11H2,1-2H3,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM302400 (US9598416, Example 46) Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN(C)CCC#N)cn2ncnc(N)c12 Show InChI InChI=1S/C21H22N6OS/c1-13-7-14-9-17(29-20(14)16(8-13)28-3)18-15(10-26(2)6-4-5-22)11-27-19(18)21(23)24-12-25-27/h7-9,11-12H,4,6,10H2,1-3H3,(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...				US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302425 (US9598416, Example 71) Show SMILES COC(C)CCN(C)Cc1cn2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1 Show InChI InChI=1S/C23H29N5O2S/c1-14-8-16-10-19(31-22(16)18(9-14)30-5)20-17(11-27(3)7-6-15(2)29-4)12-28-21(20)23(24)25-13-26-28/h8-10,12-13,15H,6-7,11H2,1-5H3,(H2,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM302416 (US9598416, Example 62) Show SMILES COC1CCCN(Cc2cn3ncnc(N)c3c2-c2cc3cc(C)cc(OC)c3s2)C1 Show InChI InChI=1S/C23H27N5O2S/c1-14-7-15-9-19(31-22(15)18(8-14)30-3)20-16(10-27-6-4-5-17(12-27)29-2)11-28-21(20)23(24)25-13-26-28/h7-9,11,13,17H,4-6,10,12H2,1-3H3,(H2,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent									US Patent US9598416 (2017) BindingDB Entry DOI: 10.7270/Q2Q2428R
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 159 total )  |  Next  |  Last  >>

Jump to: