Compile Data Set for Download or QSAR

Found 207 hits Enz. Inhib. hit(s) with all data for entry = 1897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346341 (US10202377, Compound 367) Show SMILES Cc1ccc(s1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(N)c1 Show InChI InChI=1S/C23H17N7S/c1-12-5-6-20(31-12)15-3-2-4-17-21(15)28-23(27-17)22-16-8-18(26-11-19(16)29-30-22)13-7-14(24)10-25-9-13/h2-11H,24H2,1H3,(H,27,28)(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346315 (US10202377, Compound 269) Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccsc1 Show InChI InChI=1S/C26H21N7OS/c1-14(2)26(34)29-17-8-16(10-27-11-17)21-9-19-22(12-28-21)32-33-24(19)25-30-20-5-3-4-18(23(20)31-25)15-6-7-35-13-15/h3-14H,1-2H3,(H,29,34)(H,30,31)(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346283 (US10202377, Compound 82) Show SMILES c1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccnc1 Show InChI InChI=1S/C23H15N7/c1-6-16(14-4-2-8-24-11-14)21-18(7-1)27-23(28-21)22-17-10-19(15-5-3-9-25-12-15)26-13-20(17)29-30-22/h1-13H,(H,27,28)(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346318 (US10202377, Compound 280) Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccsc1)C1CCC1 Show InChI InChI=1S/C27H21N7OS/c35-27(15-3-1-4-15)30-18-9-17(11-28-12-18)22-10-20-23(13-29-22)33-34-25(20)26-31-21-6-2-5-19(24(21)32-26)16-7-8-36-14-16/h2,5-15H,1,3-4H2,(H,30,35)(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346320 (US10202377, Compound 288) Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccoc1 Show InChI InChI=1S/C27H23N7O2/c1-15(2)8-24(35)30-18-9-17(11-28-12-18)22-10-20-23(13-29-22)33-34-26(20)27-31-21-5-3-4-19(25(21)32-27)16-6-7-36-14-16/h3-7,9-15H,8H2,1-2H3,(H,30,35)(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346309 (US10202377, Compound 238) Show SMILES c1ccc2[nH]c(nc2c1)-c1n[nH]c2cnc(cc12)-c1cccnc1 Show InChI InChI=1S/C18H12N6/c1-2-6-14-13(5-1)21-18(22-14)17-12-8-15(11-4-3-7-19-9-11)20-10-16(12)23-24-17/h1-10H,(H,21,22)(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346351 (US10202377, Compound 421) Show SMILES Cc1ccncc1-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cc(F)cc(CNS(C)(=O)=O)c1 Show InChI InChI=1S/C27H22FN7O2S/c1-15-6-7-29-13-21(15)23-11-20-24(14-30-23)34-35-26(20)27-32-22-5-3-4-19(25(22)33-27)17-8-16(9-18(28)10-17)12-31-38(2,36)37/h3-11,13-14,31H,12H2,1-2H3,(H,32,33)(H,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346339 (US10202377, Compound 358) Show SMILES Fc1ccc(s1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CCC2)c1 Show InChI InChI=1S/C27H20FN7OS/c28-23-8-7-22(37-23)17-5-2-6-19-24(17)33-26(32-19)25-18-10-20(30-13-21(18)34-35-25)15-9-16(12-29-11-15)31-27(36)14-3-1-4-14/h2,5-14H,1,3-4H2,(H,31,36)(H,32,33)(H,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346324 (US10202377, Compound 298) Show SMILES CC(C)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccoc1 Show InChI InChI=1S/C25H21N7O/c1-14(2)28-17-8-16(10-26-11-17)21-9-19-22(12-27-21)31-32-24(19)25-29-20-5-3-4-18(23(20)30-25)15-6-7-33-13-15/h3-14,28H,1-2H3,(H,29,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.9	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346285 (US10202377, Compound 90) Show SMILES CC(C)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccnc1 Show InChI InChI=1S/C26H22N8/c1-15(2)30-18-9-17(12-28-13-18)22-10-20-23(14-29-22)33-34-25(20)26-31-21-7-3-6-19(24(21)32-26)16-5-4-8-27-11-16/h3-15,30H,1-2H3,(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346332 (US10202377, Compound 321) Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccs1 Show InChI InChI=1S/C26H21N7OS/c1-14(2)26(34)29-16-9-15(11-27-12-16)20-10-18-21(13-28-20)32-33-24(18)25-30-19-6-3-5-17(23(19)31-25)22-7-4-8-35-22/h3-14H,1-2H3,(H,29,34)(H,30,31)(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.3	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346326 (US10202377, Compound 306) Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccoc1)C1CCC1 Show InChI InChI=1S/C27H21N7O2/c35-27(15-3-1-4-15)30-18-9-17(11-28-12-18)22-10-20-23(13-29-22)33-34-25(20)26-31-21-6-2-5-19(24(21)32-26)16-7-8-36-14-16/h2,5-15H,1,3-4H2,(H,30,35)(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.8	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346335 (US10202377, Compound 331) Show SMILES O=C(Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccs1)C1CC1 Show InChI InChI=1S/C26H19N7OS/c34-26(14-6-7-14)29-16-9-15(11-27-12-16)20-10-18-21(13-28-20)32-33-24(18)25-30-19-4-1-3-17(23(19)31-25)22-5-2-8-35-22/h1-5,8-14H,6-7H2,(H,29,34)(H,30,31)(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.2	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346337 (US10202377, Compound 340) Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccc(F)s1 Show InChI InChI=1S/C27H22FN7OS/c1-14(2)8-24(36)31-16-9-15(11-29-12-16)20-10-18-21(13-30-20)34-35-26(18)27-32-19-5-3-4-17(25(19)33-27)22-6-7-23(28)37-22/h3-7,9-14H,8H2,1-2H3,(H,31,36)(H,32,33)(H,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.3	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346271 (US10202377, Compound 13) Show SMILES CN(C)Cc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccc(F)c1 Show InChI InChI=1S/C27H22FN7/c1-35(2)15-16-9-18(13-29-12-16)23-11-21-24(14-30-23)33-34-26(21)27-31-22-8-4-7-20(25(22)32-27)17-5-3-6-19(28)10-17/h3-14H,15H2,1-2H3,(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.1	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346313 (US10202377, Compound 265) Show SMILES Cc1ccncc1-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccsc1 Show InChI InChI=1S/C23H16N6S/c1-13-5-7-24-10-17(13)19-9-16-20(11-25-19)28-29-22(16)23-26-18-4-2-3-15(21(18)27-23)14-6-8-30-12-14/h2-12H,1H3,(H,26,27)(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.4	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346279 (US10202377, Compound 55) Show SMILES Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccccc1F Show InChI InChI=1S/C24H16FN7/c25-18-6-2-1-4-15(18)16-5-3-7-19-22(16)30-24(29-19)23-17-9-20(28-12-21(17)31-32-23)13-8-14(26)11-27-10-13/h1-12H,26H2,(H,29,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.5	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346352 (US10202377, Compound 424) Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cc(F)cc(CNS(C)(=O)=O)c1 Show InChI InChI=1S/C31H29FN8O3S/c1-31(2,3)30(41)36-21-11-19(14-33-15-21)25-12-23-26(16-34-25)39-40-28(23)29-37-24-7-5-6-22(27(24)38-29)18-8-17(9-20(32)10-18)13-35-44(4,42)43/h5-12,14-16,35H,13H2,1-4H3,(H,36,41)(H,37,38)(H,39,40)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346344 (US10202377, Compound 381) Show SMILES CCCC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccc(C)s1 Show InChI InChI=1S/C27H23N7OS/c1-3-5-24(35)30-17-10-16(12-28-13-17)21-11-19-22(14-29-21)33-34-26(19)27-31-20-7-4-6-18(25(20)32-27)23-9-8-15(2)36-23/h4,6-14H,3,5H2,1-2H3,(H,30,35)(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.5	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346365 (US10202377, Compound 939) Show SMILES Fc1cccc(c1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C22H14FN7/c23-14-4-1-3-12(7-14)15-5-2-6-17-20(15)28-22(27-17)21-16-8-18(13-9-25-26-10-13)24-11-19(16)29-30-21/h1-11H,(H,25,26)(H,27,28)(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346355 (US10202377, Compound 436) Show SMILES CS(=O)(=O)NCc1cc(F)cc(c1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CCC2)c1 Show InChI InChI=1S/C31H27FN8O3S/c1-44(42,43)35-13-17-8-19(10-21(32)9-17)23-6-3-7-25-28(23)38-30(37-25)29-24-12-26(34-16-27(24)39-40-29)20-11-22(15-33-14-20)36-31(41)18-4-2-5-18/h3,6-12,14-16,18,35H,2,4-5,13H2,1H3,(H,36,41)(H,37,38)(H,39,40)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25.8	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346357 (US10202377, Compound 442) Show SMILES CS(=O)(=O)NCc1cc(F)cc(c1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncnc1 Show InChI InChI=1S/C25H19FN8O2S/c1-37(35,36)30-9-14-5-15(7-17(26)6-14)18-3-2-4-20-23(18)32-25(31-20)24-19-8-21(16-10-27-13-28-11-16)29-12-22(19)33-34-24/h2-8,10-13,30H,9H2,1H3,(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346333 (US10202377, Compound 325) Show SMILES CN(C)Cc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccs1 Show InChI InChI=1S/C25H21N7S/c1-32(2)14-15-9-16(12-26-11-15)20-10-18-21(13-27-20)30-31-24(18)25-28-19-6-3-5-17(23(19)29-25)22-7-4-8-33-22/h3-13H,14H2,1-2H3,(H,28,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.7	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346296 (US10202377, Compound 169) Show SMILES CN(C)Cc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)N1CCCCC1 Show InChI InChI=1S/C26H28N8/c1-33(2)16-17-11-18(14-27-13-17)21-12-19-22(15-28-21)31-32-24(19)26-29-20-7-6-8-23(25(20)30-26)34-9-4-3-5-10-34/h6-8,11-15H,3-5,9-10,16H2,1-2H3,(H,29,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.3	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346354 (US10202377, Compound 433) Show SMILES CCCC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cc(F)cc(CNS(C)(=O)=O)c1 Show InChI InChI=1S/C30H27FN8O3S/c1-3-5-27(40)35-21-11-19(14-32-15-21)25-12-23-26(16-33-25)38-39-29(23)30-36-24-7-4-6-22(28(24)37-30)18-8-17(9-20(31)10-18)13-34-43(2,41)42/h4,6-12,14-16,34H,3,5,13H2,1-2H3,(H,35,40)(H,36,37)(H,38,39)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.5	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346375 (US10202377, Compound 949) Show SMILES Oc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccc(F)c1 Show InChI InChI=1S/C24H15FN6O/c25-15-4-1-3-13(7-15)17-5-2-6-19-22(17)29-24(28-19)23-18-9-20(27-12-21(18)30-31-23)14-8-16(32)11-26-10-14/h1-12,32H,(H,28,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346321 (US10202377, Compound 292) Show SMILES CCNCc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccoc1 Show InChI InChI=1S/C25H21N7O/c1-2-26-10-15-8-17(12-27-11-15)21-9-19-22(13-28-21)31-32-24(19)25-29-20-5-3-4-18(23(20)30-25)16-6-7-33-14-16/h3-9,11-14,26H,2,10H2,1H3,(H,29,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.6	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346338 (US10202377, Compound 352) Show SMILES Fc1ccc(s1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(CN2CCCC2)c1 Show InChI InChI=1S/C27H22FN7S/c28-24-7-6-23(36-24)18-4-3-5-20-25(18)32-27(31-20)26-19-11-21(30-14-22(19)33-34-26)17-10-16(12-29-13-17)15-35-8-1-2-9-35/h3-7,10-14H,1-2,8-9,15H2,(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.5	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346319 (US10202377, Compound 283) Show SMILES C(NCc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccsc1)c1ccccc1 Show InChI InChI=1S/C30H23N7S/c1-2-5-19(6-3-1)13-31-14-20-11-22(16-32-15-20)26-12-24-27(17-33-26)36-37-29(24)30-34-25-8-4-7-23(28(25)35-30)21-9-10-38-18-21/h1-12,15-18,31H,13-14H2,(H,34,35)(H,36,37)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.9	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346340 (US10202377, Compound 366) Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccc(C)s1 Show InChI InChI=1S/C28H25N7OS/c1-15(2)9-25(36)31-18-10-17(12-29-13-18)22-11-20-23(14-30-22)34-35-27(20)28-32-21-6-4-5-19(26(21)33-28)24-8-7-16(3)37-24/h4-8,10-15H,9H2,1-3H3,(H,31,36)(H,32,33)(H,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.1	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346275 (US10202377, Compound 34) Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C29H24FN7O/c1-29(2,3)28(38)33-19-11-17(13-31-14-19)23-12-21-24(15-32-23)36-37-26(21)27-34-22-6-4-5-20(25(22)35-27)16-7-9-18(30)10-8-16/h4-15H,1-3H3,(H,33,38)(H,34,35)(H,36,37)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.2	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346346 (US10202377, Compound 392) Show SMILES CC(C)CC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccc(s1)C(C)=O Show InChI InChI=1S/C29H25N7O2S/c1-15(2)9-26(38)32-18-10-17(12-30-13-18)22-11-20-23(14-31-22)35-36-28(20)29-33-21-6-4-5-19(27(21)34-29)25-8-7-24(39-25)16(3)37/h4-8,10-15H,9H2,1-3H3,(H,32,38)(H,33,34)(H,35,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.1	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346342 (US10202377, Compound 373) Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccc(C)s1 Show InChI InChI=1S/C27H23N7OS/c1-14(2)27(35)30-17-9-16(11-28-12-17)21-10-19-22(13-29-21)33-34-25(19)26-31-20-6-4-5-18(24(20)32-26)23-8-7-15(3)36-23/h4-14H,1-3H3,(H,30,35)(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.6	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346374 (US10202377, Compound 948) Show SMILES COc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccc(F)c1 Show InChI InChI=1S/C25H17FN6O/c1-33-17-9-15(11-27-12-17)21-10-19-22(13-28-21)31-32-24(19)25-29-20-7-3-6-18(23(20)30-25)14-4-2-5-16(26)8-14/h2-13H,1H3,(H,29,30)(H,31,32)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346345 (US10202377, Compound 385) Show SMILES Cc1ccc(s1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CCCC2)c1 Show InChI InChI=1S/C29H25N7OS/c1-16-9-10-25(38-16)20-7-4-8-22-26(20)34-28(33-22)27-21-12-23(31-15-24(21)35-36-27)18-11-19(14-30-13-18)32-29(37)17-5-2-3-6-17/h4,7-15,17H,2-3,5-6H2,1H3,(H,32,37)(H,33,34)(H,35,36)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.1	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346323 (US10202377, Compound 295) Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccoc1 Show InChI InChI=1S/C26H21N7O2/c1-14(2)26(34)29-17-8-16(10-27-11-17)21-9-19-22(12-28-21)32-33-24(19)25-30-20-5-3-4-18(23(20)31-25)15-6-7-35-13-15/h3-14H,1-2H3,(H,29,34)(H,30,31)(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.3	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346356 (US10202377, Compound 439) Show SMILES CS(=O)(=O)NCc1cc(F)cc(c1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(CNCc2ccccc2)c1 Show InChI InChI=1S/C34H29FN8O2S/c1-46(44,45)39-18-22-10-24(13-26(35)12-22)27-8-5-9-29-32(27)41-34(40-29)33-28-14-30(38-20-31(28)42-43-33)25-11-23(17-37-19-25)16-36-15-21-6-3-2-4-7-21/h2-14,17,19-20,36,39H,15-16,18H2,1H3,(H,40,41)(H,42,43)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40.1	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346348 (US10202377, Compound 400) Show SMILES CC(=O)c1ccc(s1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)Cc2ccccc2)c1 Show InChI InChI=1S/C32H23N7O2S/c1-18(40)27-10-11-28(42-27)22-8-5-9-24-30(22)37-32(36-24)31-23-14-25(34-17-26(23)38-39-31)20-13-21(16-33-15-20)35-29(41)12-19-6-3-2-4-7-19/h2-11,13-17H,12H2,1H3,(H,35,41)(H,36,37)(H,38,39)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.3	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346270 (US10202377, Compound 7) Show SMILES CN(C)c1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccc(F)c1 Show InChI InChI=1S/C26H20FN7/c1-34(2)18-10-16(12-28-13-18)22-11-20-23(14-29-22)32-33-25(20)26-30-21-8-4-7-19(24(21)31-26)15-5-3-6-17(27)9-15/h3-14H,1-2H3,(H,30,31)(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.4	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346288 (US10202377, Compound 109) Show SMILES Cc1ccncc1-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccncc1 Show InChI InChI=1S/C24H17N7/c1-14-5-8-26-12-18(14)20-11-17-21(13-27-20)30-31-23(17)24-28-19-4-2-3-16(22(19)29-24)15-6-9-25-10-7-15/h2-13H,1H3,(H,28,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.5	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346317 (US10202377, Compound 277) Show SMILES CCCC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccsc1 Show InChI InChI=1S/C26H21N7OS/c1-2-4-23(34)29-17-9-16(11-27-12-17)21-10-19-22(13-28-21)32-33-25(19)26-30-20-6-3-5-18(24(20)31-26)15-7-8-35-14-15/h3,5-14H,2,4H2,1H3,(H,29,34)(H,30,31)(H,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43.5	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346269 (US10202377, Compound 1) Show SMILES CCC(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccc(F)c1 Show InChI InChI=1S/C27H20FN7O/c1-2-24(36)31-18-10-16(12-29-13-18)22-11-20-23(14-30-22)34-35-26(20)27-32-21-8-4-7-19(25(21)33-27)15-5-3-6-17(28)9-15/h3-14H,2H2,1H3,(H,31,36)(H,32,33)(H,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43.9	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346347 (US10202377, Compound 394) Show SMILES CC(=O)c1ccc(s1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cccnc1 Show InChI InChI=1S/C24H16N6OS/c1-13(31)20-7-8-21(32-20)15-5-2-6-17-22(15)28-24(27-17)23-16-10-18(14-4-3-9-25-11-14)26-12-19(16)29-30-23/h2-12H,1H3,(H,27,28)(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44.3	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346380 (US10202377, Compound 954) Show SMILES Fc1cccc(c1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cnccn1 Show InChI InChI=1S/C23H14FN7/c24-14-4-1-3-13(9-14)15-5-2-6-17-21(15)29-23(28-17)22-16-10-18(20-11-25-7-8-26-20)27-12-19(16)30-31-22/h1-12H,(H,28,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346284 (US10202377, Compound 87) Show SMILES CC(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccnc1 Show InChI InChI=1S/C27H22N8O/c1-15(2)27(36)31-18-9-17(12-29-13-18)22-10-20-23(14-30-22)34-35-25(20)26-32-21-7-3-6-19(24(21)33-26)16-5-4-8-28-11-16/h3-15H,1-2H3,(H,31,36)(H,32,33)(H,34,35)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45.4	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346366 (US10202377, Compound 940) Show SMILES Cn1cc(cn1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cccc(F)c1 Show InChI InChI=1S/C23H16FN7/c1-31-12-14(10-26-31)19-9-17-20(11-25-19)29-30-22(17)23-27-18-7-3-6-16(21(18)28-23)13-4-2-5-15(24)8-13/h2-12H,1H3,(H,27,28)(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346322 (US10202377, Compound 294) Show SMILES CC(C)(C)C(=O)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1ccoc1 Show InChI InChI=1S/C27H23N7O2/c1-27(2,3)26(35)30-17-9-16(11-28-12-17)21-10-19-22(13-29-21)33-34-24(19)25-31-20-6-4-5-18(23(20)32-25)15-7-8-36-14-15/h4-14H,1-3H3,(H,30,35)(H,31,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48.6	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346277 (US10202377, Compound 46) Show SMILES Fc1ccc(cc1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1cncc(NC(=O)C2CCC2)c1 Show InChI InChI=1S/C29H22FN7O/c30-19-9-7-16(8-10-19)21-5-2-6-23-26(21)35-28(34-23)27-22-12-24(32-15-25(22)36-37-27)18-11-20(14-31-13-18)33-29(38)17-3-1-4-17/h2,5-15,17H,1,3-4H2,(H,33,38)(H,34,35)(H,36,37)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48.9	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346360 (US10202377, Compound 454) Show SMILES CC(C)Nc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1nc2c(cccc2[nH]1)-c1cc(F)cc(NCCN(C)C)c1 Show InChI InChI=1S/C31H32FN9/c1-18(2)36-23-12-20(15-33-16-23)27-14-25-28(17-35-27)39-40-30(25)31-37-26-7-5-6-24(29(26)38-31)19-10-21(32)13-22(11-19)34-8-9-41(3)4/h5-7,10-18,34,36H,8-9H2,1-4H3,(H,37,38)(H,39,40)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51.6	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM346378 (US10202377, Compound 952) Show SMILES Fc1cccc(c1)-c1cccc2[nH]c(nc12)-c1n[nH]c2cnc(cc12)-c1ccncc1 Show InChI InChI=1S/C24H15FN6/c25-16-4-1-3-15(11-16)17-5-2-6-19-22(17)29-24(28-19)23-18-12-20(14-7-9-26-10-8-14)27-13-21(18)30-31-23/h1-13H,(H,28,29)(H,30,31)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...				US Patent US10202377 (2019) BindingDB Entry DOI: 10.7270/Q2639RV7
					More data for this Ligand-Target Pair

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