BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Cell division control protein 28'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae)	BDBM27216 ((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cdc28				Science 281: 533-538 (1998) BindingDB Entry DOI: 10.7270/Q28G8MMG
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae)	BDBM7478 (2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cdc28				Science 281: 533-538 (1998) BindingDB Entry DOI: 10.7270/Q28G8MMG
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae)	BDBM7377 (4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol \| ...) Show SMILES CCCCc1c([nH]c2nccnc12)-c1ccc(O)cc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS USR-3151 Curated by ChEMBL					Assay Description Inhibition of hemagglutinin-tagged Saccharomyces cerevisiae MNY629 Cdc28/Clb2				Bioorg Med Chem 17: 5572-82 (2009) Article DOI: 10.1016/j.bmc.2009.06.024 BindingDB Entry DOI: 10.7270/Q22J6BWT
CNRS USR-3151 Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae)	BDBM50113707 (2,6,9-Trisubstitute purine, 2 \| 2-(2-hydroxyethyla...) Show SMILES CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NCCO)nc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation counting				Science 281: 533-538 (1998) BindingDB Entry DOI: 10.7270/Q28G8MMG
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cell division control protein 28, putative (Cryptosporidium parvum (strain Iowa II))	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum Iowa II cell division control protein 28				Bioorg Med Chem 25: 1672-1680 (2017) Article DOI: 10.1016/j.bmc.2017.01.036 BindingDB Entry DOI: 10.7270/Q2PV6NXP
University of Toronto Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae)	BDBM50129555 ((1R,2R)-2-((4E,6Z)-(2S,8R,9S,11R,13S,15S,16S)-7-cy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boston University Curated by ChEMBL					Assay Description Inhibition of cyclin-dependent kinase activity of Cdc28p/CDK2p in S. cerevisiae				Bioorg Med Chem Lett 13: 2235-7 (2003) BindingDB Entry DOI: 10.7270/Q20Z72N8
Boston University Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae)	BDBM50295351 (CHEMBL560452 \| N-methyl-aloisine A) Show SMILES CCCCc1c(-c2ccc(O)cc2)n(C)c2nccnc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS USR-3151 Curated by ChEMBL					Assay Description Inhibition of hemagglutinin-tagged Saccharomyces cerevisiae MNY629 Cdc28/Clb2				Bioorg Med Chem 17: 5572-82 (2009) Article DOI: 10.1016/j.bmc.2009.06.024 BindingDB Entry DOI: 10.7270/Q22J6BWT
CNRS USR-3151 Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Saccharomyces cerevisiae)	BDBM50267719 (2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation counting				Science 281: 533-538 (1998) BindingDB Entry DOI: 10.7270/Q28G8MMG
University of California Curated by ChEMBL					More data for this Ligand-Target Pair