Found 152 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599596
(CHEMBL5191668)Show SMILES CC(=O)Nc1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599618
(CHEMBL5182242)Show SMILES OCC(=O)Nc1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599603
(CHEMBL5194835)Show SMILES CNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599620
(CHEMBL5195505)Show SMILES CS(=O)(=O)Nc1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599612
(CHEMBL5173406)Show SMILES NC(=O)CNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599624
(CHEMBL5208791)Show SMILES CNc1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599613
(CHEMBL5202114)Show SMILES O=C(Nc1cc(ccn1)-c1cc(Nc2ccccc2)cc(c1)C(=O)NCC1OCCO1)C1CC1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599594
(CHEMBL5171272)Show SMILES CNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599614
(CHEMBL5171867)Show SMILES CN(C)CCNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599606
(CHEMBL5195735)Show SMILES CNC(=O)c1cc(Nc2ccc(F)cc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599604
(CHEMBL5208569)Show SMILES CNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(C)=O)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599615
(CHEMBL5203228)Show SMILES CN(C)CCCNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599622
(CHEMBL5208135)Show SMILES CN(C)CCOc1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599623
(CHEMBL5171431)Show SMILES CN1CCN(Cc2cc(Nc3ccccc3)cc(c2)-c2ccnc(NC(=O)C3CCOCC3)c2)CC1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599621
(CHEMBL5191055)Show SMILES CNS(=O)(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599617
(CHEMBL5198244)Show SMILES CNC(=O)c1cc(Nc2ccc(F)cc2)cc(c1)-c1cc(NC(=O)C2CCOCC2)ncn1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599595
(CHEMBL5206569)Show SMILES CN(CC1OCCO1)C(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599602
(CHEMBL5203889)Show SMILES CNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599593
(CHEMBL4303547) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599607
(CHEMBL5186780)Show SMILES CNC(=O)c1cc(Nc2cccc(F)c2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599619
(CHEMBL5200538)Show SMILES CN(C(C)=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599608
(CHEMBL5170319)Show SMILES CNC(=O)c1cc(Nc2ccccc2F)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599616
(CHEMBL5201959)Show SMILES CNC(=O)c1cc(Nc2ccc(F)cc2)cc(c1)-c1cc(NC(=O)C2CCOCC2)ncc1Cl | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599609
(CHEMBL5200552)Show SMILES CNC(=O)c1cc(Nc2ccc(OC)cc2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50178832
(CHEMBL203535 | N-(2'-(phenylamino)-4,4'-bipyridin-...)Show SMILES O=C(Nc1cc(ccn1)-c1ccnc(Nc2ccccc2)c1)C1CCOC1 Show InChI InChI=1S/C21H20N4O2/c26-21(17-8-11-27-14-17)25-20-13-16(7-10-23-20)15-6-9-22-19(12-15)24-18-4-2-1-3-5-18/h1-7,9-10,12-13,17H,8,11,14H2,(H,22,24)(H,23,25,26) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599610
(CHEMBL5180360)Show SMILES CNC(=O)c1cc(Nc2ccn(C)n2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599605
(CHEMBL5188672)Show SMILES CNC(=O)c1cc(Nc2ccccc2)cc(c1)-c1ccnc(NC(=O)C2CCN(C)CC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599597
(CHEMBL5204220)Show SMILES O=C(Nc1cc(ccn1)-c1cccc(Nc2ccccc2)c1)C1CCOC1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50333221
(6-(pyridin-4-yl)benzo[d]thiazol-2-amine | CHEMBL16...)Show InChI InChI=1S/C12H9N3S/c13-12-15-10-2-1-9(7-11(10)16-12)8-3-5-14-6-4-8/h1-7H,(H2,13,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599611
(CHEMBL5178010)Show SMILES CNC(=O)c1cc(NC2CCOCC2)cc(c1)-c1ccnc(NC(=O)C2CCOCC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50545576
(CHEMBL4640712 | US11530193, Example 50)Show SMILES CC(C)(C#N)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(c1)C(C)(C)C#N |r| Show InChI InChI=1S/C24H30N8O/c1-23(2,13-25)15-8-16(24(3,4)14-26)10-18(9-15)30-21-19(20(28)33)11-29-22(31-21)32-7-5-6-17(27)12-32/h8-11,17H,5-7,12,27H2,1-4H3,(H2,28,33)(H,29,30,31)/t17-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 7.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Inhibition of human PIP5K1C using PI(4)P:PS as substrate by hotspot kinase assay |
J Med Chem 63: 6784-6801 (2020)
Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50614174
(CHEMBL5267348) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| UniChem
| | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107268
(CHEMBL3600693)Show InChI InChI=1S/C13H11N3O2S2/c1-20(17,18)12-5-3-9(7-15-12)8-2-4-10-11(6-8)19-13(14)16-10/h2-7H,1H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50545573
(CHEMBL4635883 | US11530193, Example 54)Show SMILES CC(C)c1cc(Nc2nc(ncc2C(N)=O)N2CCC[C@H](N)C2)cc(n1)C(C)C |r| Show InChI InChI=1S/C21H31N7O/c1-12(2)17-8-15(9-18(26-17)13(3)4)25-20-16(19(23)29)10-24-21(27-20)28-7-5-6-14(22)11-28/h8-10,12-14H,5-7,11,22H2,1-4H3,(H2,23,29)(H,24,25,26,27)/t14-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Inhibition of human PIP5K1C using PI(4)P:PS as substrate by hotspot kinase assay |
J Med Chem 63: 6784-6801 (2020)
Article DOI: 10.1021/acs.jmedchem.9b01803 BindingDB Entry DOI: 10.7270/Q2QF8XG3 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106970
(CHEMBL3600767)Show InChI InChI=1S/C12H9N3OS/c13-12-15-9-2-1-7(5-10(9)17-12)8-3-4-14-11(16)6-8/h1-6H,(H2,13,15)(H,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599600
(CHEMBL5178781) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599599
(CHEMBL5190001)Show SMILES CNS(=O)(=O)c1cccc(c1)-c1ccnc(NC(=O)C2CCOC2)c1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50599601
(CHEMBL5205058) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2021.116557 BindingDB Entry DOI: 10.7270/Q23J3J18 |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107255
(CHEMBL3600783)Show SMILES C[C@H](Nc1nc2ccc(cc2s1)-c1ccn(CC2CC2)c(=O)c1)C1CCOCC1 |r| Show InChI InChI=1S/C23H27N3O2S/c1-15(17-7-10-28-11-8-17)24-23-25-20-5-4-18(12-21(20)29-23)19-6-9-26(22(27)13-19)14-16-2-3-16/h4-6,9,12-13,15-17H,2-3,7-8,10-11,14H2,1H3,(H,24,25)/t15-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107015
(CHEMBL3600772)Show InChI InChI=1S/C13H14N4S/c1-2-5-17-8-10(7-15-17)9-3-4-11-12(6-9)18-13(14)16-11/h3-4,6-8H,2,5H2,1H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50333219
(6-(6-methoxypyridin-3-yl)benzo[d]thiazol-2-amine |...)Show InChI InChI=1S/C13H11N3OS/c1-17-12-5-3-9(7-15-12)8-2-4-10-11(6-8)18-13(14)16-10/h2-7H,1H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106927
(CHEMBL3600702)Show InChI InChI=1S/C11H8N4S/c12-11-15-8-3-2-7(6-9(8)16-11)10-13-4-1-5-14-10/h1-6H,(H2,12,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107276
(CHEMBL3600696)Show InChI InChI=1S/C14H12N4OS/c1-16-13(19)11-5-3-9(7-17-11)8-2-4-10-12(6-8)20-14(15)18-10/h2-7H,1H3,(H2,15,18)(H,16,19) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107272
(CHEMBL3600698)Show InChI InChI=1S/C15H15N3OS/c1-9(2)19-12-5-11(7-17-8-12)10-3-4-13-14(6-10)20-15(16)18-13/h3-9H,1-2H3,(H2,16,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106926
(CHEMBL3600701)Show InChI InChI=1S/C12H9N3S/c13-12-15-10-4-3-8(6-11(10)16-12)9-2-1-5-14-7-9/h1-7H,(H2,13,15) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107264
(CHEMBL3600688)Show InChI InChI=1S/C14H14N4S/c1-2-16-13-6-4-10(8-17-13)9-3-5-11-12(7-9)19-14(15)18-11/h3-8H,2H2,1H3,(H2,15,18)(H,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50106969
(CHEMBL3600766)Show InChI InChI=1S/C12H9N3OS/c13-12-15-9-3-1-7(5-10(9)17-12)8-2-4-11(16)14-6-8/h1-6H,(H2,13,15)(H,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107011
(CHEMBL3600768)Show InChI InChI=1S/C11H10N4S/c1-15-5-4-8(14-15)7-2-3-9-10(6-7)16-11(12)13-9/h2-6H,1H3,(H2,12,13) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107016
(CHEMBL3600773)Show InChI InChI=1S/C13H14N4S/c1-8(2)17-7-10(6-15-17)9-3-4-11-12(5-9)18-13(14)16-11/h3-8H,1-2H3,(H2,14,16) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
(Homo sapiens (Human)) | BDBM50107243
(CHEMBL3600779)Show InChI InChI=1S/C16H15N3OS/c17-16-18-13-4-3-11(7-14(13)21-16)12-5-6-19(15(20)8-12)9-10-1-2-10/h3-8,10H,1-2,9H2,(H2,17,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | <7.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay |
Bioorg Med Chem Lett 25: 3189-93 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR |
More data for this Ligand-Target Pair | |