Compile Data Set for Download or QSAR

Found 27 hits Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase type I-alpha regulatory subunit'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM50011236 (CHEMBL344314 | Isoquinoline-5-sulfonic acid (2-ami...) Show SMILES NCCNS(=O)(=O)c1cccc2cnccc12 Show InChI InChI=1S/C11H13N3O2S/c12-5-7-14-17(15,16)11-3-1-2-9-8-13-6-4-10(9)11/h1-4,6,8,14H,5,7,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	7.4	30
Nagoya University School of Medicine					Assay Description Casein kinase activities were determined under the conditions as described by Huang et al (1982).				J Biol Chem 264: 4924-7 (1989) BindingDB Entry DOI: 10.7270/Q2K072VK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM92674 (Isoquinolinesulfonamide, CKI-7) Show SMILES NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12 Show InChI InChI=1S/C11H12ClN3O2S/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10/h1-3,5,7,15H,4,6,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	5.50E+5	n/a	n/a	n/a	n/a	7.4	30
Nagoya University School of Medicine					Assay Description Casein kinase activities were determined under the conditions as described by Huang et al (1982).				J Biol Chem 264: 4924-7 (1989) BindingDB Entry DOI: 10.7270/Q2K072VK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM92673 (Isoquinolinesulfonamide, CKI-6) Show SMILES NCCNS(=O)(=O)c1cccc2ccncc12 Show InChI InChI=1S/C11H13N3O2S/c12-5-7-14-17(15,16)11-3-1-2-9-4-6-13-8-10(9)11/h1-4,6,8,14H,5,7,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	7.4	30
Nagoya University School of Medicine					Assay Description Casein kinase activities were determined under the conditions as described by Huang et al (1982).				J Biol Chem 264: 4924-7 (1989) BindingDB Entry DOI: 10.7270/Q2K072VK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81290 (MLS001148197 | N6,2'-O-DIBUTYRYLADENOSINE-3...) Show SMILES CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1OC(=O)CCC Show InChI InChI=1S/C18H24N5O8P/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/p-1/t10-,14-,15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.48E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Q81BJK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81291 (8-(4-Chlorophenylthio)adenosine 3',5'-cycl...) Show SMILES Nc1ncnc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Sc3ccc(Cl)cc3)nc12 Show InChI InChI=1S/C16H15ClN5O6PS/c17-7-1-3-8(4-2-7)30-16-21-10-13(18)19-6-20-14(10)22(16)15-11(23)12-9(27-15)5-26-29(24,25)28-12/h1-4,6,9,11-12,15,23H,5H2,(H,24,25)(H2,18,19,20)/p-1/t9-,11-,12-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	32.7	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Q81BJK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81292 (8-Bromoadenosine 3',5'-cyclic monophosphat...) Show SMILES Nc1ncnc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Br)nc12 Show InChI InChI=1S/C10H11BrN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14)/p-1/t3-,5-,6-,9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	34.4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Q81BJK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM66980 (Bucladesine sodium salt | MLS002154012 | SMR001233...) Show SMILES CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2OP([O-])(=O)OC[C@H]2[C@H]1OC(=O)CCC Show InChI InChI=1S/C18H24N5O8P/c1-3-5-11(24)22-15-13-16(20-8-19-15)23(9-21-13)17-14(29-12(25)6-4-2)10-7-28-32(26,27)31-18(10)30-17/h8-10,14,17-18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/p-1/t10-,14+,17+,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Q81BJK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81290 (MLS001148197 | N6,2'-O-DIBUTYRYLADENOSINE-3...) Show SMILES CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1OC(=O)CCC Show InChI InChI=1S/C18H24N5O8P/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/p-1/t10-,14-,15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Q81BJK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81294 (3-[(2,4-dichlorobenzyl)sulfanyl]-2-thiophenecarbox...) Show SMILES OC(=O)c1sccc1SCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C12H8Cl2O2S2/c13-8-2-1-7(9(14)5-8)6-18-10-3-4-17-11(10)12(15)16/h1-5H,6H2,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.14E+5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81295 (4-{(E)-[4-(dimethylamino)-1-naphthyl]diazenyl}benz...) Show SMILES CN(C)c1ccc(\N=N\c2ccc(cc2)S([O-])(=O)=O)c2ccccc12 Show InChI InChI=1S/C18H17N3O3S/c1-21(2)18-12-11-17(15-5-3-4-6-16(15)18)20-19-13-7-9-14(10-8-13)25(22,23)24/h3-12H,1-2H3,(H,22,23,24)/p-1/b20-19+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.14E+5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81287 (6-(6-aminopurin-9-yl)-2-ethoxy-2-oxidanylidene-4a,...) Show SMILES CCOP1(=O)OCC2OC(C(O)C2O1)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H16N5O6P/c1-2-20-24(19)21-3-6-9(23-24)8(18)12(22-6)17-5-16-7-10(13)14-4-15-11(7)17/h4-6,8-9,12,18H,2-3H2,1H3,(H2,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81288 (8-Bromoguanosine 3',5'-cyclic monophosphat...) Show SMILES Nc1nc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Br)nc2c(=O)[nH]1 Show InChI InChI=1S/C10H11BrN5O7P/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18)/p-1/t2-,4-,5-,8-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	7.83E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM51788 (5-[(2E)-2-(8-oxidanylidenequinolin-5-ylidene)hydra...) Show SMILES Oc1ccc(N=Nc2cccc3c(cccc23)S(O)(=O)=O)c2cccnc12 |w:6.6| Show InChI InChI=1S/C19H13N3O4S/c23-17-10-9-16(14-6-3-11-20-19(14)17)22-21-15-7-1-5-13-12(15)4-2-8-18(13)27(24,25)26/h1-11,23H,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.14E+5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81289 (Adenosine 3',5'-cyclic monophosphate sodiu...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1O Show InChI InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/p-1/t4-,6-,7-,10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	68.0	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81290 (MLS001148197 | N6,2'-O-DIBUTYRYLADENOSINE-3...) Show SMILES CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1OC(=O)CCC Show InChI InChI=1S/C18H24N5O8P/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/p-1/t10-,14-,15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.48E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81291 (8-(4-Chlorophenylthio)adenosine 3',5'-cycl...) Show SMILES Nc1ncnc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Sc3ccc(Cl)cc3)nc12 Show InChI InChI=1S/C16H15ClN5O6PS/c17-7-1-3-8(4-2-7)30-16-21-10-13(18)19-6-20-14(10)22(16)15-11(23)12-9(27-15)5-26-29(24,25)28-12/h1-4,6,9,11-12,15,23H,5H2,(H,24,25)(H2,18,19,20)/p-1/t9-,11-,12-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	32.7	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81292 (8-Bromoadenosine 3',5'-cyclic monophosphat...) Show SMILES Nc1ncnc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Br)nc12 Show InChI InChI=1S/C10H11BrN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14)/p-1/t3-,5-,6-,9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	34.4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM66980 (Bucladesine sodium salt | MLS002154012 | SMR001233...) Show SMILES CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2OP([O-])(=O)OC[C@H]2[C@H]1OC(=O)CCC Show InChI InChI=1S/C18H24N5O8P/c1-3-5-11(24)22-15-13-16(20-8-19-15)23(9-21-13)17-14(29-12(25)6-4-2)10-7-28-32(26,27)31-18(10)30-17/h8-10,14,17-18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/p-1/t10-,14+,17+,18+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81290 (MLS001148197 | N6,2'-O-DIBUTYRYLADENOSINE-3...) Show SMILES CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1OC(=O)CCC Show InChI InChI=1S/C18H24N5O8P/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24)/p-1/t10-,14-,15-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29Z93B6
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Homo sapiens (Human))	BDBM218808 (8-[Fluo]-cAMP) Show SMILES Nc1ncnc2n(C3OC4COP([O-])(=O)OC4C3O)c(SCCNC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)nc12 |(-9.02,-3.05,;-9.02,-4.59,;-10.36,-5.36,;-10.36,-6.9,;-9.02,-7.67,;-7.69,-6.9,;-6.23,-7.38,;-6.23,-8.92,;-7.56,-8.15,;-8.89,-8.92,;-10.38,-8.52,;-11.47,-9.61,;-12.96,-10.01,;-13.73,-8.67,;-13.73,-11.34,;-11.47,-10.41,;-10.38,-9.32,;-7.32,-10.01,;-7.32,-11.55,;-5.32,-6.13,;-3.78,-6.13,;-3.01,-4.8,;-2.24,-6.13,;-.91,-5.36,;.43,-4.59,;.43,-3.05,;1.76,-5.36,;3.3,-5.36,;4.07,-4.03,;5.61,-4.03,;6.38,-5.36,;5.61,-6.7,;4.07,-6.7,;6.01,-8.18,;4.92,-9.27,;7.5,-8.58,;7.92,-5.36,;8.69,-6.7,;7.92,-8.03,;8.69,-9.36,;10.23,-9.36,;11,-10.7,;11,-8.03,;10.23,-6.7,;11,-5.36,;10.23,-4.03,;11,-2.7,;10.23,-1.36,;11,-.03,;8.69,-1.36,;7.92,-2.69,;8.69,-4.03,;-6.23,-4.89,;-7.69,-5.36,)| Show InChI InChI=1S/C33H28N7O11PS2/c34-28-25-29(37-13-36-28)40(30-26(43)27-23(50-30)12-48-52(46,47)51-27)33(39-25)54-8-7-35-32(53)38-14-1-4-17(20(9-14)31(44)45)24-18-5-2-15(41)10-21(18)49-22-11-16(42)3-6-19(22)24/h1-6,9-11,13,23,26-27,30,41,43H,7-8,12H2,(H,44,45)(H,46,47)(H2,34,36,37)(H2,35,38,53)/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a
University of California, San Diego					Assay Description The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...				Biochemistry 56: 1536-1545 (2017) Article DOI: 10.1021/acs.biochem.6b01152 BindingDB Entry DOI: 10.7270/Q2DJ5DHF
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit [R241A] (Homo sapiens (Human))	BDBM218808 (8-[Fluo]-cAMP) Show SMILES Nc1ncnc2n(C3OC4COP([O-])(=O)OC4C3O)c(SCCNC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)nc12 |(-9.02,-3.05,;-9.02,-4.59,;-10.36,-5.36,;-10.36,-6.9,;-9.02,-7.67,;-7.69,-6.9,;-6.23,-7.38,;-6.23,-8.92,;-7.56,-8.15,;-8.89,-8.92,;-10.38,-8.52,;-11.47,-9.61,;-12.96,-10.01,;-13.73,-8.67,;-13.73,-11.34,;-11.47,-10.41,;-10.38,-9.32,;-7.32,-10.01,;-7.32,-11.55,;-5.32,-6.13,;-3.78,-6.13,;-3.01,-4.8,;-2.24,-6.13,;-.91,-5.36,;.43,-4.59,;.43,-3.05,;1.76,-5.36,;3.3,-5.36,;4.07,-4.03,;5.61,-4.03,;6.38,-5.36,;5.61,-6.7,;4.07,-6.7,;6.01,-8.18,;4.92,-9.27,;7.5,-8.58,;7.92,-5.36,;8.69,-6.7,;7.92,-8.03,;8.69,-9.36,;10.23,-9.36,;11,-10.7,;11,-8.03,;10.23,-6.7,;11,-5.36,;10.23,-4.03,;11,-2.7,;10.23,-1.36,;11,-.03,;8.69,-1.36,;7.92,-2.69,;8.69,-4.03,;-6.23,-4.89,;-7.69,-5.36,)| Show InChI InChI=1S/C33H28N7O11PS2/c34-28-25-29(37-13-36-28)40(30-26(43)27-23(50-30)12-48-52(46,47)51-27)33(39-25)54-8-7-35-32(53)38-14-1-4-17(20(9-14)31(44)45)24-18-5-2-15(41)10-21(18)49-22-11-16(42)3-6-19(22)24/h1-6,9-11,13,23,26-27,30,41,43H,7-8,12H2,(H,44,45)(H,46,47)(H2,34,36,37)(H2,35,38,53)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.72	n/a	n/a	n/a	n/a	n/a
University of California, San Diego					Assay Description The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...				Biochemistry 56: 1536-1545 (2017) Article DOI: 10.1021/acs.biochem.6b01152 BindingDB Entry DOI: 10.7270/Q2DJ5DHF
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit [K242A] (Homo sapiens (Human))	BDBM218808 (8-[Fluo]-cAMP) Show SMILES Nc1ncnc2n(C3OC4COP([O-])(=O)OC4C3O)c(SCCNC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)nc12 |(-9.02,-3.05,;-9.02,-4.59,;-10.36,-5.36,;-10.36,-6.9,;-9.02,-7.67,;-7.69,-6.9,;-6.23,-7.38,;-6.23,-8.92,;-7.56,-8.15,;-8.89,-8.92,;-10.38,-8.52,;-11.47,-9.61,;-12.96,-10.01,;-13.73,-8.67,;-13.73,-11.34,;-11.47,-10.41,;-10.38,-9.32,;-7.32,-10.01,;-7.32,-11.55,;-5.32,-6.13,;-3.78,-6.13,;-3.01,-4.8,;-2.24,-6.13,;-.91,-5.36,;.43,-4.59,;.43,-3.05,;1.76,-5.36,;3.3,-5.36,;4.07,-4.03,;5.61,-4.03,;6.38,-5.36,;5.61,-6.7,;4.07,-6.7,;6.01,-8.18,;4.92,-9.27,;7.5,-8.58,;7.92,-5.36,;8.69,-6.7,;7.92,-8.03,;8.69,-9.36,;10.23,-9.36,;11,-10.7,;11,-8.03,;10.23,-6.7,;11,-5.36,;10.23,-4.03,;11,-2.7,;10.23,-1.36,;11,-.03,;8.69,-1.36,;7.92,-2.69,;8.69,-4.03,;-6.23,-4.89,;-7.69,-5.36,)| Show InChI InChI=1S/C33H28N7O11PS2/c34-28-25-29(37-13-36-28)40(30-26(43)27-23(50-30)12-48-52(46,47)51-27)33(39-25)54-8-7-35-32(53)38-14-1-4-17(20(9-14)31(44)45)24-18-5-2-15(41)10-21(18)49-22-11-16(42)3-6-19(22)24/h1-6,9-11,13,23,26-27,30,41,43H,7-8,12H2,(H,44,45)(H,46,47)(H2,34,36,37)(H2,35,38,53)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.32	n/a	n/a	n/a	n/a	n/a
University of California, San Diego					Assay Description The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...				Biochemistry 56: 1536-1545 (2017) Article DOI: 10.1021/acs.biochem.6b01152 BindingDB Entry DOI: 10.7270/Q2DJ5DHF
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit [R243A] (Homo sapiens (Human))	BDBM218808 (8-[Fluo]-cAMP) Show SMILES Nc1ncnc2n(C3OC4COP([O-])(=O)OC4C3O)c(SCCNC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)nc12 |(-9.02,-3.05,;-9.02,-4.59,;-10.36,-5.36,;-10.36,-6.9,;-9.02,-7.67,;-7.69,-6.9,;-6.23,-7.38,;-6.23,-8.92,;-7.56,-8.15,;-8.89,-8.92,;-10.38,-8.52,;-11.47,-9.61,;-12.96,-10.01,;-13.73,-8.67,;-13.73,-11.34,;-11.47,-10.41,;-10.38,-9.32,;-7.32,-10.01,;-7.32,-11.55,;-5.32,-6.13,;-3.78,-6.13,;-3.01,-4.8,;-2.24,-6.13,;-.91,-5.36,;.43,-4.59,;.43,-3.05,;1.76,-5.36,;3.3,-5.36,;4.07,-4.03,;5.61,-4.03,;6.38,-5.36,;5.61,-6.7,;4.07,-6.7,;6.01,-8.18,;4.92,-9.27,;7.5,-8.58,;7.92,-5.36,;8.69,-6.7,;7.92,-8.03,;8.69,-9.36,;10.23,-9.36,;11,-10.7,;11,-8.03,;10.23,-6.7,;11,-5.36,;10.23,-4.03,;11,-2.7,;10.23,-1.36,;11,-.03,;8.69,-1.36,;7.92,-2.69,;8.69,-4.03,;-6.23,-4.89,;-7.69,-5.36,)| Show InChI InChI=1S/C33H28N7O11PS2/c34-28-25-29(37-13-36-28)40(30-26(43)27-23(50-30)12-48-52(46,47)51-27)33(39-25)54-8-7-35-32(53)38-14-1-4-17(20(9-14)31(44)45)24-18-5-2-15(41)10-21(18)49-22-11-16(42)3-6-19(22)24/h1-6,9-11,13,23,26-27,30,41,43H,7-8,12H2,(H,44,45)(H,46,47)(H2,34,36,37)(H2,35,38,53)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.29	n/a	n/a	n/a	n/a	n/a
University of California, San Diego					Assay Description The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...				Biochemistry 56: 1536-1545 (2017) Article DOI: 10.1021/acs.biochem.6b01152 BindingDB Entry DOI: 10.7270/Q2DJ5DHF
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81289 (Adenosine 3',5'-cyclic monophosphate sodiu...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1O Show InChI InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/p-1/t4-,6-,7-,10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	68.0	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Q81BJK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit [K244A] (Homo sapiens (Human))	BDBM218808 (8-[Fluo]-cAMP) Show SMILES Nc1ncnc2n(C3OC4COP([O-])(=O)OC4C3O)c(SCCNC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)nc12 |(-9.02,-3.05,;-9.02,-4.59,;-10.36,-5.36,;-10.36,-6.9,;-9.02,-7.67,;-7.69,-6.9,;-6.23,-7.38,;-6.23,-8.92,;-7.56,-8.15,;-8.89,-8.92,;-10.38,-8.52,;-11.47,-9.61,;-12.96,-10.01,;-13.73,-8.67,;-13.73,-11.34,;-11.47,-10.41,;-10.38,-9.32,;-7.32,-10.01,;-7.32,-11.55,;-5.32,-6.13,;-3.78,-6.13,;-3.01,-4.8,;-2.24,-6.13,;-.91,-5.36,;.43,-4.59,;.43,-3.05,;1.76,-5.36,;3.3,-5.36,;4.07,-4.03,;5.61,-4.03,;6.38,-5.36,;5.61,-6.7,;4.07,-6.7,;6.01,-8.18,;4.92,-9.27,;7.5,-8.58,;7.92,-5.36,;8.69,-6.7,;7.92,-8.03,;8.69,-9.36,;10.23,-9.36,;11,-10.7,;11,-8.03,;10.23,-6.7,;11,-5.36,;10.23,-4.03,;11,-2.7,;10.23,-1.36,;11,-.03,;8.69,-1.36,;7.92,-2.69,;8.69,-4.03,;-6.23,-4.89,;-7.69,-5.36,)| Show InChI InChI=1S/C33H28N7O11PS2/c34-28-25-29(37-13-36-28)40(30-26(43)27-23(50-30)12-48-52(46,47)51-27)33(39-25)54-8-7-35-32(53)38-14-1-4-17(20(9-14)31(44)45)24-18-5-2-15(41)10-21(18)49-22-11-16(42)3-6-19(22)24/h1-6,9-11,13,23,26-27,30,41,43H,7-8,12H2,(H,44,45)(H,46,47)(H2,34,36,37)(H2,35,38,53)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.71	n/a	n/a	n/a	n/a	n/a
University of California, San Diego					Assay Description The ability of the R subunit basic patch mutants to bind cAMP in the absence of the C subunit was tested using the fluorescent cAMP analogue, 8-[fluo...				Biochemistry 56: 1536-1545 (2017) Article DOI: 10.1021/acs.biochem.6b01152 BindingDB Entry DOI: 10.7270/Q2DJ5DHF
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81287 (6-(6-aminopurin-9-yl)-2-ethoxy-2-oxidanylidene-4a,...) Show SMILES CCOP1(=O)OCC2OC(C(O)C2O1)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H16N5O6P/c1-2-20-24(19)21-3-6-9(23-24)8(18)12(22-6)17-5-16-7-10(13)14-4-15-11(7)17/h4-6,8-9,12,18H,2-3H2,1H3,(H2,13,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Q81BJK
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase type I-alpha regulatory subunit (Bos taurus)	BDBM81288 (8-Bromoguanosine 3',5'-cyclic monophosphat...) Show SMILES Nc1nc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Br)nc2c(=O)[nH]1 Show InChI InChI=1S/C10H11BrN5O7P/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18)/p-1/t2-,4-,5-,8-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	7.83E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Q81BJK
					More data for this Ligand-Target Pair