Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161472 (US9108978, 2.02) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 30 | -44.7 | 203 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161468 (US9108978, 6.09) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB US Patent | 90 | -41.8 | 530 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161472 (US9108978, 2.02) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 225 | -39.5 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161472 (US9108978, 2.02) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 420 | -37.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161470 (US9108978, 4.01) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | 660 | -36.7 | 4.00E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161469 (US9108978, 6.07) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.17E+3 | -35.2 | 7.00E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161467 (US9108978, 3.25) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.83E+3 | -34.1 | 1.16E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161471 (US9108978, 6.34) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >1.00E+4 | >-29.7 | >5.00E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161468 (US9108978, 6.09) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | US Patent | >3.00E+4 | >-26.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161470 (US9108978, 4.01) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | US Patent | >3.00E+4 | >-26.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161470 (US9108978, 4.01) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | US Patent | >3.00E+4 | >-26.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161469 (US9108978, 6.07) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >3.00E+4 | >-26.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161467 (US9108978, 3.25) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >3.00E+4 | >-26.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161469 (US9108978, 6.07) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >3.00E+4 | >-26.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161467 (US9108978, 3.25) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >3.00E+4 | >-26.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Escherichia coli) | BDBM161468 (US9108978, 6.09) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | US Patent | >3.00E+4 | >-26.9 | n/a | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair |