Affinity Data by Patent

Patent code US9018213

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM155943 (US9018213, 14) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.1	n/a	n/a	n/a	n/a	7.4	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description Competitive binding test for receptors: 20 μl of each of the test compounds and 20 μl of the radioactive ligand together with 160 μl o...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM155943 (US9018213, 14) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description (1) The prepared membrane was first applied with appropriate amount of homogenized liquid, and homogenizer was used for evenly dispersing. 15 tubes w...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM155947 (US9018213, 19) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description (1) The prepared membrane was first applied with appropriate amount of homogenized liquid, and homogenizer was used for evenly dispersing. 15 tubes w...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM155935 (US9018213, 5) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.90	n/a	n/a	n/a	n/a	7.4	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description Competitive binding test for receptors: 20 μl of each of the test compounds and 20 μl of the radioactive ligand together with 160 μl o...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50448210 (CHEMBL3120697 \| US9018213, 15) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	7.4	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description Competitive binding test for receptors: 20 μl of each of the test compounds and 20 μl of the radioactive ligand together with 160 μl o...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50448210 (CHEMBL3120697 \| US9018213, 15) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description (1) The prepared membrane was first applied with appropriate amount of homogenized liquid, and homogenizer was used for evenly dispersing. 15 tubes w...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM155935 (US9018213, 5) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description (1) The prepared membrane was first applied with appropriate amount of homogenized liquid, and homogenizer was used for evenly dispersing. 15 tubes w...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM155937 (US9018213, 7) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description (1) The prepared membrane was first applied with appropriate amount of homogenized liquid, and homogenizer was used for evenly dispersing. 15 tubes w...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	25.7	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description (1) The prepared membrane was first applied with appropriate amount of homogenized liquid, and homogenizer was used for evenly dispersing. 15 tubes w...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM155937 (US9018213, 7) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.40	n/a	n/a	n/a	n/a	7.4	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description Competitive binding test for receptors: 20 μl of each of the test compounds and 20 μl of the radioactive ligand together with 160 μl o...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50130293 (7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	37.9	n/a	n/a	n/a	n/a	7.4	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description Competitive binding test for receptors: 20 μl of each of the test compounds and 20 μl of the radioactive ligand together with 160 μl o...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM155947 (US9018213, 19) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13.2	n/a	n/a	n/a	n/a	7.4	n/a
Huazhong University of Science & Technology; NHWA Pharma. Corporation US Patent					Assay Description Competitive binding test for receptors: 20 μl of each of the test compounds and 20 μl of the radioactive ligand together with 160 μl o...				US Patent US9018213 (2015) BindingDB Entry DOI: 10.7270/Q27M06N0
					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%