Affinity Data by Patent

Patent code US9187474

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM192504 (US9187474, 76) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM192503 (US9187474, 18) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM192504 (US9187474, 76) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase A-Raf (Homo sapiens (Human))	BDBM192503 (US9187474, 18) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM192503 (US9187474, 18) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM192503 (US9187474, 18) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase A-Raf (Homo sapiens (Human))	BDBM192504 (US9187474, 76) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM192504 (US9187474, 76) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Deciphera Pharmaceuticals, LLC; Eli Lilly and Company US Patent					Assay Description Sample preparation: A375 cells from ATCC are lysed by sonication in commercially available lysis buffer, cleared by centrifugation, and the resulting...				US Patent US9187474 (2015) BindingDB Entry DOI: 10.7270/Q2HH6HWK
					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%